Incidental Mutation 'IGL02551:Vmn2r62'
ID298099
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Vmn2r62
Ensembl Gene ENSMUSG00000091926
Gene Namevomeronasal 2, receptor 62
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.103) question?
Stock #IGL02551
Quality Score
Status
Chromosome7
Chromosomal Location42764438-42793496 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) T to C at 42788506 bp
ZygosityHeterozygous
Amino Acid Change Threonine to Alanine at position 185 (T185A)
Ref Sequence ENSEMBL: ENSMUSP00000130557 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000169130]
Predicted Effect probably benign
Transcript: ENSMUST00000169130
AA Change: T185A

PolyPhen 2 Score 0.017 (Sensitivity: 0.95; Specificity: 0.80)
SMART Domains Protein: ENSMUSP00000130557
Gene: ENSMUSG00000091926
AA Change: T185A

DomainStartEndE-ValueType
signal peptide 1 18 N/A INTRINSIC
Pfam:ANF_receptor 77 471 2.1e-43 PFAM
Pfam:NCD3G 514 567 2.7e-23 PFAM
Pfam:7tm_3 600 835 6e-52 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 57 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
1600012P17Rik G A 1: 158,969,048 noncoding transcript Het
Abca8a T C 11: 110,084,242 I109V probably benign Het
Acsm2 C T 7: 119,573,284 P117S probably damaging Het
Adamts18 C A 8: 113,699,072 C1186F probably damaging Het
Adamts5 A T 16: 85,870,038 V522E possibly damaging Het
Adcy10 A G 1: 165,543,233 T694A probably damaging Het
Adgra2 G A 8: 27,119,222 V609I probably benign Het
Agbl3 A G 6: 34,823,071 K638R possibly damaging Het
Alpk2 T A 18: 65,372,751 N66I probably damaging Het
Ap3b1 T A 13: 94,418,091 I245N probably damaging Het
Aqp9 A G 9: 71,132,640 V120A probably damaging Het
Arhgef17 T C 7: 100,930,346 E465G probably damaging Het
Btrc G T 19: 45,423,134 C31F possibly damaging Het
Calhm2 G A 19: 47,133,100 S210L probably damaging Het
Cnksr3 C A 10: 7,152,912 K153N probably damaging Het
Cnr1 T C 4: 33,943,686 S25P probably benign Het
Dnajc6 T A 4: 101,639,353 W838R probably damaging Het
Fam78a T A 2: 32,069,556 T181S probably damaging Het
Fat1 A G 8: 45,051,398 T4600A probably damaging Het
Fbxo31 A T 8: 121,566,344 Y101N probably damaging Het
Glmp A G 3: 88,325,082 M1V probably null Het
Gsdmc T A 15: 63,801,933 T168S probably benign Het
Has1 C T 17: 17,848,298 V265I probably damaging Het
Hmcn2 A G 2: 31,454,811 D4670G possibly damaging Het
Kcnj4 C T 15: 79,484,902 M292I probably benign Het
Kmo A T 1: 175,637,919 S80C probably damaging Het
Lrrc8d C T 5: 105,813,548 T608I possibly damaging Het
Mical2 A T 7: 112,323,990 N635I probably benign Het
Nags T C 11: 102,147,941 S403P probably damaging Het
Nalcn T A 14: 123,323,338 I776F probably benign Het
Ncan A T 8: 70,102,462 N1018K probably damaging Het
Notch3 T A 17: 32,154,731 probably benign Het
Nup93 C T 8: 94,227,833 Q53* probably null Het
Pdk2 T A 11: 95,028,586 M288L probably benign Het
Pkd1 A G 17: 24,573,815 Y1492C probably damaging Het
Pla2g12b T A 10: 59,403,870 W34R probably damaging Het
Pla2g6 T A 15: 79,299,094 D511V possibly damaging Het
Plin2 C A 4: 86,658,692 M265I probably benign Het
Ppp6c A T 2: 39,206,657 F78I probably damaging Het
Prop1 A T 11: 50,950,946 M211K possibly damaging Het
Prr14l T A 5: 32,831,484 E222D probably damaging Het
Rtkn A T 6: 83,151,924 I454F probably damaging Het
Serinc2 T C 4: 130,260,774 I226V probably benign Het
Sh3bp1 T A 15: 78,904,338 H229Q probably benign Het
Slc13a3 G T 2: 165,424,573 F348L probably damaging Het
Slc6a15 T A 10: 103,404,275 probably benign Het
Spg7 G A 8: 123,076,978 G249E probably damaging Het
Tbc1d2 T C 4: 46,649,916 D40G probably benign Het
Tmcc2 A G 1: 132,357,579 L683P probably damaging Het
Triobp T C 15: 78,973,489 S1097P probably benign Het
Tspan9 T C 6: 127,965,763 D167G probably null Het
Ttll6 T C 11: 96,154,700 I581T probably benign Het
Usp29 A G 7: 6,963,353 probably null Het
Vgll4 A G 6: 114,862,293 W246R probably damaging Het
Vmn2r26 T C 6: 124,026,141 V170A probably benign Het
Vwce A G 19: 10,645,036 H234R possibly damaging Het
Zfp292 T C 4: 34,806,462 E2194G possibly damaging Het
Other mutations in Vmn2r62
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01726:Vmn2r62 APN 7 42765102 missense probably damaging 1.00
IGL01900:Vmn2r62 APN 7 42789071 missense probably benign 0.01
IGL02799:Vmn2r62 UTSW 7 42787972 missense possibly damaging 0.65
R0144:Vmn2r62 UTSW 7 42789016 missense probably damaging 1.00
R1396:Vmn2r62 UTSW 7 42764837 missense probably damaging 0.99
R1846:Vmn2r62 UTSW 7 42789122 missense probably damaging 0.97
R3738:Vmn2r62 UTSW 7 42787887 missense probably benign 0.00
R4519:Vmn2r62 UTSW 7 42764533 missense probably damaging 1.00
R5138:Vmn2r62 UTSW 7 42764816 missense possibly damaging 0.90
R5381:Vmn2r62 UTSW 7 42787795 missense probably benign 0.43
R6855:Vmn2r62 UTSW 7 42788988 missense probably benign 0.00
R6872:Vmn2r62 UTSW 7 42788988 missense probably benign 0.00
R6968:Vmn2r62 UTSW 7 42788442 missense probably benign 0.18
R7030:Vmn2r62 UTSW 7 42789049 missense possibly damaging 0.82
R7067:Vmn2r62 UTSW 7 42764878 missense probably benign 0.44
R7148:Vmn2r62 UTSW 7 42765216 missense probably benign 0.02
R7305:Vmn2r62 UTSW 7 42764811 missense possibly damaging 0.76
R7493:Vmn2r62 UTSW 7 42787892 missense possibly damaging 0.81
R7583:Vmn2r62 UTSW 7 42788042 missense possibly damaging 0.76
R7593:Vmn2r62 UTSW 7 42787789 missense possibly damaging 0.55
R7851:Vmn2r62 UTSW 7 42789115 missense probably benign 0.00
R7974:Vmn2r62 UTSW 7 42764607 missense probably damaging 0.98
R7974:Vmn2r62 UTSW 7 42787857 missense probably damaging 1.00
R8085:Vmn2r62 UTSW 7 42787846 missense probably damaging 0.99
R8514:Vmn2r62 UTSW 7 42764568 missense probably benign 0.00
Posted On2015-04-16