Incidental Mutation 'IGL02576:Tex16'
ID299201
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Tex16
Ensembl Gene ENSMUSG00000034555
Gene Nametestis expressed gene 16
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.092) question?
Stock #IGL02576
Quality Score
Status
ChromosomeX
Chromosomal Location112011007-112127326 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) T to A at 112118956 bp
ZygosityHeterozygous
Amino Acid Change Leucine to Glutamine at position 384 (L384Q)
Ref Sequence ENSEMBL: ENSMUSP00000118847 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000038546] [ENSMUST00000130247] [ENSMUST00000207962]
Predicted Effect probably benign
Transcript: ENSMUST00000038546
AA Change: L373Q

PolyPhen 2 Score 0.072 (Sensitivity: 0.94; Specificity: 0.84)
SMART Domains Protein: ENSMUSP00000048187
Gene: ENSMUSG00000034555
AA Change: L373Q

DomainStartEndE-ValueType
low complexity region 1 12 N/A INTRINSIC
low complexity region 110 122 N/A INTRINSIC
low complexity region 616 669 N/A INTRINSIC
low complexity region 674 699 N/A INTRINSIC
low complexity region 811 824 N/A INTRINSIC
low complexity region 833 850 N/A INTRINSIC
Predicted Effect probably benign
Transcript: ENSMUST00000130247
AA Change: L384Q

PolyPhen 2 Score 0.072 (Sensitivity: 0.94; Specificity: 0.84)
SMART Domains Protein: ENSMUSP00000118847
Gene: ENSMUSG00000034555
AA Change: L384Q

DomainStartEndE-ValueType
low complexity region 10 24 N/A INTRINSIC
low complexity region 121 133 N/A INTRINSIC
low complexity region 627 680 N/A INTRINSIC
low complexity region 685 710 N/A INTRINSIC
low complexity region 822 835 N/A INTRINSIC
low complexity region 844 861 N/A INTRINSIC
Predicted Effect probably benign
Transcript: ENSMUST00000207962
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 48 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Abca16 A G 7: 120,433,455 I232M probably benign Het
Ace G A 11: 105,974,111 V537M probably damaging Het
Alg1 A G 16: 5,244,529 E425G possibly damaging Het
Cacng3 G A 7: 122,671,910 S46N probably benign Het
Cdc45 C T 16: 18,798,729 M200I probably benign Het
Cfap65 A G 1: 74,903,458 S1646P probably damaging Het
Col20a1 C T 2: 181,013,405 Q1152* probably null Het
D130043K22Rik A C 13: 24,856,870 T92P possibly damaging Het
Drc3 T C 11: 60,370,551 M176T probably benign Het
Esyt3 T C 9: 99,315,225 R851G probably benign Het
Fbxo43 A G 15: 36,152,175 V496A probably benign Het
Fut4 T A 9: 14,751,405 M198L probably damaging Het
Galt C T 4: 41,755,953 probably benign Het
Glipr1l1 A G 10: 112,060,319 K4E possibly damaging Het
Gm9945 A G 11: 53,480,351 probably benign Het
Hspa12a A C 19: 58,799,410 I660R possibly damaging Het
Htr3b T C 9: 48,945,504 I225V possibly damaging Het
Igf2r T C 17: 12,748,763 D23G possibly damaging Het
Igsf5 A G 16: 96,386,581 I158V probably benign Het
Itgae A G 11: 73,118,505 Y505C possibly damaging Het
Kif16b A G 2: 142,862,545 probably benign Het
Kif26b T C 1: 178,916,347 V1336A probably benign Het
Kmt2d A G 15: 98,864,120 S450P unknown Het
Lexm T C 4: 106,591,628 D411G possibly damaging Het
Lhfpl2 G A 13: 94,174,226 M1I probably null Het
Lig4 A G 8: 9,971,116 I888T probably damaging Het
Msh4 G A 3: 153,867,746 T563M probably damaging Het
Muc5ac C T 7: 141,817,044 A3238V probably benign Het
Myo15b A G 11: 115,890,053 S1246G probably null Het
Olfr193 T C 16: 59,109,771 I280V probably benign Het
Pecam1 G A 11: 106,671,774 T599M probably damaging Het
Phf3 G A 1: 30,830,036 P644S probably benign Het
Pkd1l1 A C 11: 8,844,560 F2317C possibly damaging Het
Prdm4 A G 10: 85,900,937 M613T possibly damaging Het
Prim2 A T 1: 33,484,717 I371N probably damaging Het
Ptprs T C 17: 56,414,958 D1316G probably damaging Het
Rnf19b C T 4: 129,073,522 R285* probably null Het
Secisbp2 A G 13: 51,670,858 N381D possibly damaging Het
Slc28a2 T C 2: 122,458,171 I586T probably damaging Het
Spef1 T C 2: 131,174,642 H11R possibly damaging Het
Taar4 T C 10: 23,961,011 L173S probably damaging Het
Tas2r123 T C 6: 132,847,740 F200S possibly damaging Het
Tox2 A G 2: 163,276,180 Q168R probably damaging Het
Trim5 T A 7: 104,278,417 E172V probably damaging Het
Txndc11 G A 16: 11,075,017 probably benign Het
Vmn1r232 T A 17: 20,913,913 I142F probably benign Het
Zdhhc25 A T 15: 88,601,269 H269L probably benign Het
Znrf4 T C 17: 56,512,199 D36G probably damaging Het
Other mutations in Tex16
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01712:Tex16 APN X 112093754 missense probably damaging 1.00
IGL03261:Tex16 APN X 112118855 missense possibly damaging 0.90
R2274:Tex16 UTSW X 112121141 missense probably damaging 0.98
R3607:Tex16 UTSW X 112093970 missense probably damaging 1.00
R4209:Tex16 UTSW X 112120943 missense probably benign 0.01
R4210:Tex16 UTSW X 112120943 missense probably benign 0.01
U24488:Tex16 UTSW X 112119118 missense probably benign 0.05
Posted On2015-04-16