Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02582:Nlrp4g'

299367

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Nlrp4g

Ensembl Gene

ENSMUSG00000079741

Gene Name

NLR family, pyrin domain containing 4G

Synonyms

nalp4g

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.078) question?

Stock #

IGL02582

Quality Score

Status

Chromosome

Chromosomal Location

124117991-124126089 bp(-) (GRCm39)

Type of Mutation

unclassified

DNA Base Change (assembly)

A to C at 124349764 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Gene Model

predicted gene model for transcript(s):

AlphaFold

no structure available at present

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000067621

SMART Domains

Protein: ENSMUSP00000065508
Gene: ENSMUSG00000079741

Domain	Start	End	E-Value	Type
Pfam:NACHT	69	238	1.5e-39	PFAM
Blast:LRR	555	582	9e-10	BLAST
Blast:LRR	610	637	7e-10	BLAST

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000214229

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000215276

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000215602

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000216416

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000217178

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000217183

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 46 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Acat1	T	A	9: 53,506,045 (GRCm39)	I92F	probably benign	Het
Actr3b	A	G	5: 26,037,411 (GRCm39)	I208V	probably benign	Het
Car12	T	C	9: 66,621,159 (GRCm39)	V10A	probably benign	Het
Ccdc171	C	A	4: 83,661,255 (GRCm39)	R1122S	probably damaging	Het
Cep97	A	G	16: 55,742,539 (GRCm39)	V136A	probably damaging	Het
Cilp2	G	T	8: 70,333,936 (GRCm39)	Q1021K	probably damaging	Het
Col24a1	C	A	3: 145,020,247 (GRCm39)	T206N	probably damaging	Het
Crebbp	A	T	16: 3,902,141 (GRCm39)	I2328K	possibly damaging	Het
Ctns	A	G	11: 73,087,478 (GRCm39)	F16S	probably benign	Het
Dbf4	T	C	5: 8,453,172 (GRCm39)	K276E	probably benign	Het
Dnase2b	T	A	3: 146,294,840 (GRCm39)	Q118L	probably benign	Het
Elf1	T	C	14: 79,773,819 (GRCm39)	L10P	probably damaging	Het
Exosc5	T	C	7: 25,364,988 (GRCm39)		probably null	Het
Fam163b	C	T	2: 27,003,570 (GRCm39)	C28Y	probably damaging	Het
Fam180a	G	T	6: 35,290,647 (GRCm39)	A112E	possibly damaging	Het
Fam3b	A	T	16: 97,272,391 (GRCm39)	Y89*	probably null	Het
Gcg	C	T	2: 62,308,922 (GRCm39)	W77*	probably null	Het
Gm17472	G	A	6: 42,957,832 (GRCm39)	V34I	possibly damaging	Het
Klhl23	T	A	2: 69,654,582 (GRCm39)	C151S	probably damaging	Het
Mdh1b	T	A	1: 63,758,756 (GRCm39)	I279F	probably benign	Het
Mfsd11	T	A	11: 116,764,701 (GRCm39)	I375N	probably damaging	Het
Mroh2b	T	A	15: 4,937,997 (GRCm39)	I206N	probably damaging	Het
Myo1b	T	C	1: 51,821,133 (GRCm39)	E456G	possibly damaging	Het
Nat8	G	A	6: 85,807,783 (GRCm39)	Q117*	probably null	Het
Nmt1	G	T	11: 102,955,625 (GRCm39)	G468C	possibly damaging	Het
Nobox	G	T	6: 43,281,973 (GRCm39)	Q367K	possibly damaging	Het
Nusap1	A	G	2: 119,479,470 (GRCm39)	*428W	probably null	Het
Or12j4	T	C	7: 140,046,560 (GRCm39)	F149L	probably benign	Het
Or4c126	G	A	2: 89,824,656 (GRCm39)	M306I	probably benign	Het
Pbp2	T	C	6: 135,287,147 (GRCm39)	I67V	probably benign	Het
Pcdhb8	T	G	18: 37,488,427 (GRCm39)	M35R	possibly damaging	Het
Pkp1	T	C	1: 135,817,664 (GRCm39)	E157G	probably damaging	Het
Pomgnt1	C	T	4: 116,015,747 (GRCm39)	L560F	probably damaging	Het
Prkcz	T	C	4: 155,355,713 (GRCm39)	T227A	probably damaging	Het
Ptprd	T	A	4: 75,865,361 (GRCm39)	R1446S	probably damaging	Het
Ptprq	T	C	10: 107,479,860 (GRCm39)	T1137A	probably benign	Het
Sec22c	T	C	9: 121,514,630 (GRCm39)	I153V	probably benign	Het
Slc30a5	C	T	13: 100,949,155 (GRCm39)		probably null	Het
Smcr8	T	C	11: 60,669,721 (GRCm39)	S290P	probably benign	Het
Stambpl1	T	G	19: 34,212,612 (GRCm39)	L261V	probably benign	Het
Stk38l	T	C	6: 146,668,321 (GRCm39)		probably null	Het
Themis	T	C	10: 28,637,543 (GRCm39)	F216L	probably benign	Het
Trmt1l	T	C	1: 151,309,536 (GRCm39)		probably benign	Het
Usp17lb	C	A	7: 104,489,937 (GRCm39)	C330F	probably damaging	Het
Vmn2r120	A	T	17: 57,831,724 (GRCm39)	L355H	probably damaging	Het
Zc3h7b	T	A	15: 81,653,341 (GRCm39)	C82S	probably benign	Het

Other mutations in Nlrp4g

Allele	Source	Chr	Coord	Type	Predicted Effect
IGL01066:Nlrp4g	APN	9	124,349,526 (GRCm38)	unclassified	noncoding transcript
IGL01087:Nlrp4g	APN	9	124,353,858 (GRCm38)	critical splice acceptor site	noncoding transcript
IGL01106:Nlrp4g	APN	9	124,350,452 (GRCm38)	unclassified	noncoding transcript
IGL01938:Nlrp4g	APN	9	124,349,068 (GRCm38)	unclassified	noncoding transcript
IGL02088:Nlrp4g	APN	9	124,350,453 (GRCm38)	unclassified	noncoding transcript
IGL02170:Nlrp4g	APN	9	124,348,980 (GRCm38)	unclassified	noncoding transcript
IGL02588:Nlrp4g	APN	9	124,348,843 (GRCm38)	unclassified	noncoding transcript
IGL02931:Nlrp4g	APN	9	124,348,940 (GRCm38)	unclassified	noncoding transcript
IGL03111:Nlrp4g	APN	9	124,353,978 (GRCm38)	exon	noncoding transcript
IGL03373:Nlrp4g	APN	9	124,349,853 (GRCm38)	unclassified	noncoding transcript
R0617:Nlrp4g	UTSW	9	124,349,540 (GRCm38)	unclassified	noncoding transcript
R1419:Nlrp4g	UTSW	9	124,349,434 (GRCm38)	unclassified	noncoding transcript
R2060:Nlrp4g	UTSW	9	124,349,693 (GRCm38)	unclassified	noncoding transcript
R2152:Nlrp4g	UTSW	9	124,353,339 (GRCm38)	exon	noncoding transcript
R2356:Nlrp4g	UTSW	9	124,349,306 (GRCm38)	unclassified	noncoding transcript
R2384:Nlrp4g	UTSW	9	124,349,707 (GRCm38)	unclassified	noncoding transcript
R2698:Nlrp4g	UTSW	9	124,349,630 (GRCm38)	unclassified	noncoding transcript
R3878:Nlrp4g	UTSW	9	124,349,362 (GRCm38)	unclassified	noncoding transcript
R4640:Nlrp4g	UTSW	9	124,349,153 (GRCm38)	unclassified	noncoding transcript
R4745:Nlrp4g	UTSW	9	124,349,515 (GRCm38)	unclassified	noncoding transcript
R4754:Nlrp4g	UTSW	9	124,349,788 (GRCm38)	unclassified	noncoding transcript
R4937:Nlrp4g	UTSW	9	124,354,005 (GRCm38)	exon	noncoding transcript
R5024:Nlrp4g	UTSW	9	124,350,155 (GRCm38)	unclassified	noncoding transcript
R5162:Nlrp4g	UTSW	9	124,350,394 (GRCm38)	unclassified	noncoding transcript
R5407:Nlrp4g	UTSW	9	124,349,930 (GRCm38)	unclassified	noncoding transcript
R5521:Nlrp4g	UTSW	9	124,350,020 (GRCm38)	unclassified	noncoding transcript
R8224:Nlrp4g	UTSW	9	124,353,374 (GRCm38)	missense	noncoding transcript
R8259:Nlrp4g	UTSW	9	124,353,392 (GRCm38)	missense	noncoding transcript
Z1088:Nlrp4g	UTSW	9	124,349,201 (GRCm38)	unclassified	noncoding transcript

Posted On

2015-04-16