Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02586:Gm10250'

299551

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Gm10250

Ensembl Gene

ENSMUSG00000068706

Gene Name

predicted pseudogene 10250

Synonyms

Accession Numbers

Essential gene?

Probably essential (E-score: 0.789) question?

Stock #

IGL02586

Quality Score

Status

Chromosome

Chromosomal Location

5150136-5150617 bp(-) (GRCm39)

Type of Mutation

unclassified

DNA Base Change (assembly)

T to A at 5150412 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000046506 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000045356] [ENSMUST00000090488]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000045356

SMART Domains

Protein: ENSMUSP00000046506
Gene: ENSMUSG00000041841

Domain	Start	End	E-Value	Type
Pfam:Ribosomal_L37e	2	54	3.9e-30	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000090488

SMART Domains

Protein: ENSMUSP00000087974
Gene: ENSMUSG00000068706

Domain	Start	End	E-Value	Type
Pfam:Mt_ATP-synt_D	3	159	8.7e-70	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000104549

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000226758

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000227111

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000227463

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000227635

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000227674

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 38 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abca13	A	G	11: 9,243,983 (GRCm39)	I1949V	possibly damaging	Het
Anapc2	T	A	2: 25,175,108 (GRCm39)	M742K	probably benign	Het
Arhgef12	T	A	9: 42,917,200 (GRCm39)	K380*	probably null	Het
Armc1	G	T	3: 19,188,192 (GRCm39)		probably benign	Het
Bltp1	G	A	3: 37,098,757 (GRCm39)	W4626*	probably null	Het
Diaph3	A	T	14: 87,223,512 (GRCm39)	L323*	probably null	Het
Fbxo11	C	T	17: 88,318,711 (GRCm39)		probably benign	Het
Flywch1	C	T	17: 23,974,676 (GRCm39)	A655T	probably benign	Het
Frmpd1	A	G	4: 45,285,160 (GRCm39)	D1327G	probably damaging	Het
Ggact	G	A	14: 123,128,942 (GRCm39)	T91I	possibly damaging	Het
Gsdmc4	T	C	15: 63,765,641 (GRCm39)	S303G	probably damaging	Het
Helt	T	C	8: 46,746,276 (GRCm39)	E15G	probably damaging	Het
Kcnf1	T	A	12: 17,226,144 (GRCm39)	S26C	probably benign	Het
Lilra6	T	C	7: 3,911,819 (GRCm39)	T280A	probably benign	Het
Lipo3	A	T	19: 33,559,539 (GRCm39)	D110E	possibly damaging	Het
Mepe	C	A	5: 104,485,316 (GRCm39)	T152N	probably benign	Het
Nr2f1	C	A	13: 78,343,275 (GRCm39)		probably benign	Het
Or5ak24	T	C	2: 85,260,810 (GRCm39)	D121G	possibly damaging	Het
Or6c214	A	G	10: 129,590,524 (GRCm39)	I265T	possibly damaging	Het
Peg3	T	C	7: 6,713,068 (GRCm39)	D718G	probably benign	Het
Phf2	A	T	13: 48,967,334 (GRCm39)		probably benign	Het
Pigc	A	T	1: 161,798,503 (GRCm39)	I162F	probably benign	Het
Raf1	A	G	6: 115,597,267 (GRCm39)	L11P	probably damaging	Het
Rlf	T	C	4: 121,007,261 (GRCm39)	Y573C	probably damaging	Het
Rnf123	G	A	9: 107,945,501 (GRCm39)	R390*	probably null	Het
Rnf149	T	G	1: 39,604,296 (GRCm39)	Q189P	probably benign	Het
Slc11a1	T	C	1: 74,424,291 (GRCm39)		probably benign	Het
Slc22a12	C	T	19: 6,590,487 (GRCm39)	M234I	probably benign	Het
Slc28a1	A	T	7: 80,814,167 (GRCm39)	I455F	probably benign	Het
Slc35f5	T	G	1: 125,512,273 (GRCm39)	L358V	probably damaging	Het
Slc47a1	A	T	11: 61,235,147 (GRCm39)	V562D	probably benign	Het
Srrm1	G	A	4: 135,052,415 (GRCm39)	P658L	unknown	Het
Ushbp1	T	C	8: 71,841,394 (GRCm39)		probably benign	Het
Vmn1r88	T	A	7: 12,911,735 (GRCm39)	Y30*	probably null	Het
Vmn2r27	A	T	6: 124,201,434 (GRCm39)	Y174*	probably null	Het
Wwox	T	C	8: 115,438,947 (GRCm39)	Y338H	possibly damaging	Het
Zfp518a	G	A	19: 40,903,061 (GRCm39)	G997R	probably damaging	Het
Zup1	A	T	10: 33,811,261 (GRCm39)		probably benign	Het

Other mutations in Gm10250

Allele	Source	Chr	Coord	Type	Predicted Effect
R0130:Gm10250	UTSW	15	5,150,473 (GRCm39)	splice site	probably null
R1758:Gm10250	UTSW	15	5,150,509 (GRCm39)	unclassified	probably benign
R2098:Gm10250	UTSW	15	5,150,296 (GRCm39)	unclassified	probably benign
R4782:Gm10250	UTSW	15	5,150,578 (GRCm39)	unclassified	probably benign

Posted On

2015-04-16