Incidental Mutation 'IGL02587:Zfp955b'
| ID |
299586 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Zfp955b
|
| Ensembl Gene |
ENSMUSG00000096910 |
| Gene Name |
zinc finger protein 955B |
| Synonyms |
C430039G02Rik, A430003O12Rik, Gm4455 |
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.065)
|
| Stock # |
IGL02587
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
17 |
| Chromosomal Location |
33508518-33526215 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to A
at 33519624 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamine to Lysine
at position 31
(Q31K)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000097011
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000099414]
|
| AlphaFold |
L7N232 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000099414
AA Change: Q31K
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000097011
Gene: ENSMUSG00000096910
AA Change: Q31K
| Domain | Start | End | E-Value | Type |
|---|
|
KRAB
|
10 |
70 |
3.04e-14 |
SMART |
|
ZnF_C2H2
|
230 |
252 |
7.68e0 |
SMART |
|
ZnF_C2H2
|
258 |
280 |
5.72e-1 |
SMART |
|
ZnF_C2H2
|
290 |
312 |
6.75e0 |
SMART |
|
ZnF_C2H2
|
318 |
340 |
5.81e-2 |
SMART |
|
ZnF_C2H2
|
346 |
368 |
3.16e-3 |
SMART |
|
ZnF_C2H2
|
374 |
396 |
1.18e-2 |
SMART |
|
ZnF_C2H2
|
402 |
424 |
7.78e-3 |
SMART |
|
ZnF_C2H2
|
430 |
452 |
3.16e-3 |
SMART |
|
ZnF_C2H2
|
458 |
480 |
1.1e-2 |
SMART |
|
ZnF_C2H2
|
486 |
508 |
2.09e-3 |
SMART |
|
ZnF_C2H2
|
514 |
536 |
6.67e-2 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000182230
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 25 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| AAdacl4fm3 |
G |
A |
4: 144,429,969 (GRCm39) |
T340I |
possibly damaging |
Het |
| Acot10 |
A |
T |
15: 20,665,883 (GRCm39) |
V286E |
possibly damaging |
Het |
| Bpifa6 |
T |
C |
2: 153,831,130 (GRCm39) |
L232P |
probably damaging |
Het |
| Calr4 |
A |
G |
4: 109,096,134 (GRCm39) |
N104S |
possibly damaging |
Het |
| Cdc42bpa |
A |
G |
1: 179,921,510 (GRCm39) |
E550G |
possibly damaging |
Het |
| Cfhr4 |
G |
A |
1: 139,629,668 (GRCm39) |
T712I |
probably damaging |
Het |
| D3Ertd751e |
T |
A |
3: 41,708,287 (GRCm39) |
N141K |
probably benign |
Het |
| Emilin2 |
A |
G |
17: 71,587,851 (GRCm39) |
|
probably benign |
Het |
| Eml6 |
T |
C |
11: 29,734,236 (GRCm39) |
E1168G |
possibly damaging |
Het |
| Fbxo48 |
T |
C |
11: 16,903,659 (GRCm39) |
I95T |
probably benign |
Het |
| Fpr3 |
A |
T |
17: 18,190,953 (GRCm39) |
T75S |
probably benign |
Het |
| Gm5145 |
A |
G |
17: 20,791,452 (GRCm39) |
K277E |
probably damaging |
Het |
| Gnao1 |
A |
G |
8: 94,677,067 (GRCm39) |
|
probably benign |
Het |
| Krt8 |
G |
A |
15: 101,907,367 (GRCm39) |
R239C |
probably benign |
Het |
| Lrrc17 |
A |
T |
5: 21,766,078 (GRCm39) |
N187Y |
probably damaging |
Het |
| Neil1 |
C |
T |
9: 57,052,263 (GRCm39) |
R195H |
probably damaging |
Het |
| Nr2f1 |
C |
A |
13: 78,343,275 (GRCm39) |
|
probably benign |
Het |
| Pi4ka |
C |
A |
16: 17,135,217 (GRCm39) |
G946W |
probably damaging |
Het |
| Plcg2 |
A |
T |
8: 118,284,852 (GRCm39) |
N159I |
possibly damaging |
Het |
| Rad54l |
A |
G |
4: 115,962,994 (GRCm39) |
Y335H |
probably damaging |
Het |
| Rgsl1 |
C |
T |
1: 153,675,684 (GRCm39) |
R159H |
probably damaging |
Het |
| Scn11a |
T |
C |
9: 119,634,750 (GRCm39) |
D357G |
probably damaging |
Het |
| Srrm1 |
G |
A |
4: 135,052,415 (GRCm39) |
P658L |
unknown |
Het |
| Timeless |
A |
G |
10: 128,075,785 (GRCm39) |
M6V |
probably damaging |
Het |
| Vps16 |
T |
C |
2: 130,281,636 (GRCm39) |
|
probably null |
Het |
|
| Other mutations in Zfp955b |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00537:Zfp955b
|
APN |
17 |
33,521,847 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02073:Zfp955b
|
APN |
17 |
33,519,564 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
IGL02126:Zfp955b
|
APN |
17 |
33,521,238 (GRCm39) |
nonsense |
probably null |
|
|
IGL02237:Zfp955b
|
APN |
17 |
33,520,893 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02971:Zfp955b
|
APN |
17 |
33,519,940 (GRCm39) |
missense |
probably benign |
0.11 |
|
IGL03034:Zfp955b
|
APN |
17 |
33,521,142 (GRCm39) |
missense |
probably benign |
0.22 |
|
IGL03493:Zfp955b
|
APN |
17 |
33,521,519 (GRCm39) |
missense |
probably benign |
0.35 |
|
R0269:Zfp955b
|
UTSW |
17 |
33,524,437 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0373:Zfp955b
|
UTSW |
17 |
33,521,496 (GRCm39) |
missense |
probably benign |
|
|
R0617:Zfp955b
|
UTSW |
17 |
33,524,437 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0684:Zfp955b
|
UTSW |
17 |
33,521,947 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1778:Zfp955b
|
UTSW |
17 |
33,521,788 (GRCm39) |
missense |
probably benign |
0.07 |
|
R1874:Zfp955b
|
UTSW |
17 |
33,524,427 (GRCm39) |
missense |
probably benign |
0.10 |
|
R3893:Zfp955b
|
UTSW |
17 |
33,521,968 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3938:Zfp955b
|
UTSW |
17 |
33,524,390 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4082:Zfp955b
|
UTSW |
17 |
33,521,129 (GRCm39) |
missense |
probably benign |
0.08 |
|
R4672:Zfp955b
|
UTSW |
17 |
33,524,233 (GRCm39) |
unclassified |
probably benign |
|
|
R4956:Zfp955b
|
UTSW |
17 |
33,524,209 (GRCm39) |
unclassified |
probably benign |
|
|
R4998:Zfp955b
|
UTSW |
17 |
33,524,125 (GRCm39) |
unclassified |
probably benign |
|
|
R5276:Zfp955b
|
UTSW |
17 |
33,522,031 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5341:Zfp955b
|
UTSW |
17 |
33,524,095 (GRCm39) |
unclassified |
probably benign |
|
|
R5558:Zfp955b
|
UTSW |
17 |
33,521,161 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R6086:Zfp955b
|
UTSW |
17 |
33,521,478 (GRCm39) |
missense |
probably benign |
|
|
R6170:Zfp955b
|
UTSW |
17 |
33,521,084 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6306:Zfp955b
|
UTSW |
17 |
33,522,160 (GRCm39) |
missense |
probably benign |
0.07 |
|
R6519:Zfp955b
|
UTSW |
17 |
33,521,051 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R9286:Zfp955b
|
UTSW |
17 |
33,521,683 (GRCm39) |
missense |
probably benign |
0.04 |
|
| Posted On |
2015-04-16 |
Incidental Mutation