Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02588:Nlrp4g'

299597

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Nlrp4g

Ensembl Gene

ENSMUSG00000079741

Gene Name

NLR family, pyrin domain containing 4G

Synonyms

nalp4g

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.074) question?

Stock #

IGL02588

Quality Score

Status

Chromosome

Chromosomal Location

124117991-124126089 bp(-) (GRCm39)

Type of Mutation

unclassified

DNA Base Change (assembly)

T to C at 124348843 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Gene Model

predicted gene model for transcript(s):

AlphaFold

no structure available at present

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000067621

SMART Domains

Protein: ENSMUSP00000065508
Gene: ENSMUSG00000079741

Domain	Start	End	E-Value	Type
Pfam:NACHT	69	238	1.5e-39	PFAM
Blast:LRR	555	582	9e-10	BLAST
Blast:LRR	610	637	7e-10	BLAST

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000214229

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000215276

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000215602

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000216416

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000217178

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000217183

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 46 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Akap6	G	A	12: 52,933,282 (GRCm39)	W258*	probably null	Het
Ankmy2	T	C	12: 36,226,685 (GRCm39)		probably benign	Het
Arhgap26	G	T	18: 38,734,670 (GRCm39)		probably benign	Het
Aspscr1	A	G	11: 120,568,357 (GRCm39)	D60G	possibly damaging	Het
Cdh15	C	A	8: 123,583,291 (GRCm39)	Y31*	probably null	Het
Cnih3	A	G	1: 181,237,269 (GRCm39)	R76G	probably benign	Het
Cplx1	C	A	5: 108,673,289 (GRCm39)	R44L	possibly damaging	Het
Dhx57	T	A	17: 80,576,300 (GRCm39)	I597F	probably damaging	Het
Dnah17	G	T	11: 117,916,479 (GRCm39)	F4231L	possibly damaging	Het
Dst	T	G	1: 34,156,565 (GRCm39)	L173R	probably damaging	Het
Fezf2	A	T	14: 12,343,687 (GRCm38)	Y353N	probably damaging	Het
Ghrhr	T	A	6: 55,360,395 (GRCm39)	L247Q	probably damaging	Het
Gm10912	C	T	2: 103,897,197 (GRCm39)		probably benign	Het
Gpcpd1	A	T	2: 132,376,673 (GRCm39)	L541H	probably damaging	Het
Gpld1	C	T	13: 25,127,682 (GRCm39)	T28I	probably damaging	Het
Lmf2	A	T	15: 89,239,609 (GRCm39)		probably null	Het
Lratd2	T	C	15: 60,694,999 (GRCm39)	D249G	probably damaging	Het
Mex3c	A	G	18: 73,723,116 (GRCm39)	N403S	probably damaging	Het
Nlrp1b	A	T	11: 71,073,105 (GRCm39)	L246*	probably null	Het
Nlrp2	A	T	7: 5,330,551 (GRCm39)	L615*	probably null	Het
Nlrp4c	A	T	7: 6,087,647 (GRCm39)	D760V	probably benign	Het
Nr2f1	C	A	13: 78,343,275 (GRCm39)		probably benign	Het
Nuggc	T	A	14: 65,855,226 (GRCm39)		probably benign	Het
Or4c122	T	C	2: 89,080,042 (GRCm39)		probably benign	Het
Or52d1	C	T	7: 103,756,260 (GRCm39)	T258I	possibly damaging	Het
Papolg	T	A	11: 23,840,252 (GRCm39)	I75F	probably damaging	Het
Pcdhgc5	A	G	18: 37,955,003 (GRCm39)	Y759C	probably damaging	Het
Pdp2	A	G	8: 105,321,536 (GRCm39)	K462E	possibly damaging	Het
Plod1	A	T	4: 147,997,747 (GRCm39)	L654*	probably null	Het
Ppp4r3b	G	T	11: 29,148,853 (GRCm39)	G25*	probably null	Het
Ptch1	T	C	13: 63,659,732 (GRCm39)	D1307G	probably benign	Het
Ranbp17	A	G	11: 33,167,361 (GRCm39)	V1034A	probably benign	Het
Rbl2	T	A	8: 91,813,712 (GRCm39)	L319Q	probably damaging	Het
Retnlg	A	G	16: 48,693,255 (GRCm39)	T11A	probably benign	Het
Rfc3	A	T	5: 151,566,381 (GRCm39)	F356Y	possibly damaging	Het
Rnf213	G	T	11: 119,307,362 (GRCm39)	C674F	probably benign	Het
Shcbp1l	A	G	1: 153,304,411 (GRCm39)	K157E	probably benign	Het
Slc22a17	A	G	14: 55,145,451 (GRCm39)	C233R	probably damaging	Het
Slc38a9	A	G	13: 112,834,511 (GRCm39)		probably null	Het
Srrm1	G	A	4: 135,052,415 (GRCm39)	P658L	unknown	Het
St14	C	A	9: 31,001,329 (GRCm39)		probably benign	Het
Sympk	G	A	7: 18,776,550 (GRCm39)	V481M	probably benign	Het
Timeless	T	A	10: 128,079,203 (GRCm39)	L350Q	probably damaging	Het
Tnfrsf1a	A	G	6: 125,337,729 (GRCm39)	I229V	probably benign	Het
Ugt3a1	A	T	15: 9,361,542 (GRCm39)	H106L	probably benign	Het
Zbtb45	A	T	7: 12,740,204 (GRCm39)	C470*	probably null	Het

Other mutations in Nlrp4g

Allele	Source	Chr	Coord	Type	Predicted Effect
IGL01066:Nlrp4g	APN	9	124,349,526 (GRCm38)	unclassified	noncoding transcript
IGL01087:Nlrp4g	APN	9	124,353,858 (GRCm38)	critical splice acceptor site	noncoding transcript
IGL01106:Nlrp4g	APN	9	124,350,452 (GRCm38)	unclassified	noncoding transcript
IGL01938:Nlrp4g	APN	9	124,349,068 (GRCm38)	unclassified	noncoding transcript
IGL02088:Nlrp4g	APN	9	124,350,453 (GRCm38)	unclassified	noncoding transcript
IGL02170:Nlrp4g	APN	9	124,348,980 (GRCm38)	unclassified	noncoding transcript
IGL02582:Nlrp4g	APN	9	124,349,764 (GRCm38)	unclassified	noncoding transcript
IGL02931:Nlrp4g	APN	9	124,348,940 (GRCm38)	unclassified	noncoding transcript
IGL03111:Nlrp4g	APN	9	124,353,978 (GRCm38)	exon	noncoding transcript
IGL03373:Nlrp4g	APN	9	124,349,853 (GRCm38)	unclassified	noncoding transcript
R0617:Nlrp4g	UTSW	9	124,349,540 (GRCm38)	unclassified	noncoding transcript
R1419:Nlrp4g	UTSW	9	124,349,434 (GRCm38)	unclassified	noncoding transcript
R2060:Nlrp4g	UTSW	9	124,349,693 (GRCm38)	unclassified	noncoding transcript
R2152:Nlrp4g	UTSW	9	124,353,339 (GRCm38)	exon	noncoding transcript
R2356:Nlrp4g	UTSW	9	124,349,306 (GRCm38)	unclassified	noncoding transcript
R2384:Nlrp4g	UTSW	9	124,349,707 (GRCm38)	unclassified	noncoding transcript
R2698:Nlrp4g	UTSW	9	124,349,630 (GRCm38)	unclassified	noncoding transcript
R3878:Nlrp4g	UTSW	9	124,349,362 (GRCm38)	unclassified	noncoding transcript
R4640:Nlrp4g	UTSW	9	124,349,153 (GRCm38)	unclassified	noncoding transcript
R4745:Nlrp4g	UTSW	9	124,349,515 (GRCm38)	unclassified	noncoding transcript
R4754:Nlrp4g	UTSW	9	124,349,788 (GRCm38)	unclassified	noncoding transcript
R4937:Nlrp4g	UTSW	9	124,354,005 (GRCm38)	exon	noncoding transcript
R5024:Nlrp4g	UTSW	9	124,350,155 (GRCm38)	unclassified	noncoding transcript
R5162:Nlrp4g	UTSW	9	124,350,394 (GRCm38)	unclassified	noncoding transcript
R5407:Nlrp4g	UTSW	9	124,349,930 (GRCm38)	unclassified	noncoding transcript
R5521:Nlrp4g	UTSW	9	124,350,020 (GRCm38)	unclassified	noncoding transcript
R8224:Nlrp4g	UTSW	9	124,353,374 (GRCm38)	missense	noncoding transcript
R8259:Nlrp4g	UTSW	9	124,353,392 (GRCm38)	missense	noncoding transcript
Z1088:Nlrp4g	UTSW	9	124,349,201 (GRCm38)	unclassified	noncoding transcript

Posted On

2015-04-16