Incidental Mutation 'IGL02602:Vmn1r191'
ID300106
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Vmn1r191
Ensembl Gene ENSMUSG00000095916
Gene Namevomeronasal 1 receptor 191
SynonymsV1rh15
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.108) question?
Stock #IGL02602
Quality Score
Status
Chromosome13
Chromosomal Location22178686-22179582 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) T to C at 22179465 bp
ZygosityHeterozygous
Amino Acid Change Lysine to Glutamic Acid at position 40 (K40E)
Ref Sequence ENSEMBL: ENSMUSP00000072206 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000072369]
Predicted Effect probably damaging
Transcript: ENSMUST00000072369
AA Change: K40E

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
SMART Domains Protein: ENSMUSP00000072206
Gene: ENSMUSG00000095916
AA Change: K40E

DomainStartEndE-ValueType
transmembrane domain 12 34 N/A INTRINSIC
Pfam:V1R 35 291 4.4e-33 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000120067
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 33 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Acsf2 A G 11: 94,570,465 probably benign Het
Arhgap20 A T 9: 51,825,843 I148F probably damaging Het
Arhgef10 C T 8: 14,930,198 A146V probably benign Het
Cdk13 A G 13: 17,727,160 F997L probably damaging Het
Cep162 G A 9: 87,246,153 H170Y probably benign Het
Clasp1 T C 1: 118,471,785 F220L probably damaging Het
Clock C A 5: 76,254,426 G129V probably null Het
Clock C T 5: 76,254,427 G129R probably damaging Het
Cybrd1 T C 2: 71,118,148 L10P probably damaging Het
Cyp7a1 A G 4: 6,272,871 I114T possibly damaging Het
Epha7 T A 4: 28,871,877 V402D possibly damaging Het
Fam228a G A 12: 4,732,808 T95I probably benign Het
Gm7589 C T 9: 59,146,158 noncoding transcript Het
Klf4 C A 4: 55,530,595 R172L probably damaging Het
Macf1 A G 4: 123,355,163 S7190P probably damaging Het
Mga A G 2: 119,931,884 T1119A possibly damaging Het
Nmur2 T A 11: 56,027,063 T367S probably benign Het
Ogfr A G 2: 180,595,437 D605G possibly damaging Het
Olfr1314 A G 2: 112,092,561 F47L probably benign Het
Pcdhb1 A T 18: 37,266,796 N600I probably damaging Het
Pkhd1l1 T C 15: 44,557,931 S3032P probably damaging Het
Ppp2r5e A G 12: 75,493,439 L144P probably damaging Het
Rnf123 G A 9: 108,068,302 R390* probably null Het
Ryr2 T C 13: 11,554,511 probably benign Het
Scarb2 A G 5: 92,448,556 Y410H probably benign Het
Slc12a1 A G 2: 125,154,242 Y105C probably damaging Het
Srrm1 G A 4: 135,325,104 P658L unknown Het
Stt3b A T 9: 115,276,778 S210T probably damaging Het
Sulf2 T C 2: 166,081,300 H635R probably benign Het
Tmem167 C A 13: 90,104,380 R52S probably damaging Het
Tsga13 G A 6: 30,902,277 T167I possibly damaging Het
Txk T C 5: 72,707,720 R271G possibly damaging Het
Vmn1r69 T A 7: 10,579,974 N277Y probably benign Het
Other mutations in Vmn1r191
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00233:Vmn1r191 APN 13 22178720 missense probably damaging 1.00
IGL01645:Vmn1r191 APN 13 22179444 missense probably benign 0.03
IGL02224:Vmn1r191 APN 13 22178898 missense probably damaging 1.00
IGL02321:Vmn1r191 APN 13 22178898 nonsense probably null
IGL02516:Vmn1r191 APN 13 22179540 missense probably benign 0.38
IGL02630:Vmn1r191 APN 13 22179261 missense possibly damaging 0.95
IGL03077:Vmn1r191 APN 13 22179146 missense probably benign 0.07
IGL03380:Vmn1r191 APN 13 22178885 missense probably damaging 0.99
R0571:Vmn1r191 UTSW 13 22179047 missense probably damaging 0.96
R0981:Vmn1r191 UTSW 13 22179219 missense probably benign 0.00
R1672:Vmn1r191 UTSW 13 22179092 missense probably benign 0.01
R1955:Vmn1r191 UTSW 13 22178815 missense possibly damaging 0.79
R1969:Vmn1r191 UTSW 13 22178782 missense possibly damaging 0.71
R5059:Vmn1r191 UTSW 13 22178993 missense probably damaging 1.00
R6484:Vmn1r191 UTSW 13 22178748 missense probably benign 0.00
R6736:Vmn1r191 UTSW 13 22179550 missense probably benign 0.14
R7063:Vmn1r191 UTSW 13 22178694 missense probably benign 0.08
R7475:Vmn1r191 UTSW 13 22178772 missense probably benign 0.00
Posted On2015-04-16