Incidental Mutation 'IGL02602:Tsga13'
ID300133
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Tsga13
Ensembl Gene ENSMUSG00000039032
Gene Nametestis specific gene A13
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.147) question?
Stock #IGL02602
Quality Score
Status
Chromosome6
Chromosomal Location30896981-30915573 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) G to A at 30902277 bp
ZygosityHeterozygous
Amino Acid Change Threonine to Isoleucine at position 167 (T167I)
Ref Sequence ENSEMBL: ENSMUSP00000040894 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000048580]
Predicted Effect possibly damaging
Transcript: ENSMUST00000048580
AA Change: T167I

PolyPhen 2 Score 0.920 (Sensitivity: 0.81; Specificity: 0.94)
SMART Domains Protein: ENSMUSP00000040894
Gene: ENSMUSG00000039032
AA Change: T167I

DomainStartEndE-ValueType
Pfam:TSGA13 3 271 9.5e-125 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000139006
Predicted Effect noncoding transcript
Transcript: ENSMUST00000201230
Predicted Effect noncoding transcript
Transcript: ENSMUST00000202703
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 33 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Acsf2 A G 11: 94,570,465 probably benign Het
Arhgap20 A T 9: 51,825,843 I148F probably damaging Het
Arhgef10 C T 8: 14,930,198 A146V probably benign Het
Cdk13 A G 13: 17,727,160 F997L probably damaging Het
Cep162 G A 9: 87,246,153 H170Y probably benign Het
Clasp1 T C 1: 118,471,785 F220L probably damaging Het
Clock C A 5: 76,254,426 G129V probably null Het
Clock C T 5: 76,254,427 G129R probably damaging Het
Cybrd1 T C 2: 71,118,148 L10P probably damaging Het
Cyp7a1 A G 4: 6,272,871 I114T possibly damaging Het
Epha7 T A 4: 28,871,877 V402D possibly damaging Het
Fam228a G A 12: 4,732,808 T95I probably benign Het
Gm7589 C T 9: 59,146,158 noncoding transcript Het
Klf4 C A 4: 55,530,595 R172L probably damaging Het
Macf1 A G 4: 123,355,163 S7190P probably damaging Het
Mga A G 2: 119,931,884 T1119A possibly damaging Het
Nmur2 T A 11: 56,027,063 T367S probably benign Het
Ogfr A G 2: 180,595,437 D605G possibly damaging Het
Olfr1314 A G 2: 112,092,561 F47L probably benign Het
Pcdhb1 A T 18: 37,266,796 N600I probably damaging Het
Pkhd1l1 T C 15: 44,557,931 S3032P probably damaging Het
Ppp2r5e A G 12: 75,493,439 L144P probably damaging Het
Rnf123 G A 9: 108,068,302 R390* probably null Het
Ryr2 T C 13: 11,554,511 probably benign Het
Scarb2 A G 5: 92,448,556 Y410H probably benign Het
Slc12a1 A G 2: 125,154,242 Y105C probably damaging Het
Srrm1 G A 4: 135,325,104 P658L unknown Het
Stt3b A T 9: 115,276,778 S210T probably damaging Het
Sulf2 T C 2: 166,081,300 H635R probably benign Het
Tmem167 C A 13: 90,104,380 R52S probably damaging Het
Txk T C 5: 72,707,720 R271G possibly damaging Het
Vmn1r191 T C 13: 22,179,465 K40E probably damaging Het
Vmn1r69 T A 7: 10,579,974 N277Y probably benign Het
Other mutations in Tsga13
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01631:Tsga13 APN 6 30913566 missense possibly damaging 0.47
IGL02487:Tsga13 APN 6 30907427 missense probably damaging 1.00
R3894:Tsga13 UTSW 6 30912263 missense probably benign
R4335:Tsga13 UTSW 6 30900045 missense probably damaging 0.97
R4582:Tsga13 UTSW 6 30902363 missense probably benign 0.04
R5705:Tsga13 UTSW 6 30900016 missense probably damaging 1.00
R6248:Tsga13 UTSW 6 30897204 missense probably benign 0.01
R7470:Tsga13 UTSW 6 30900046 missense possibly damaging 0.70
Posted On2015-04-16