Incidental Mutation 'IGL02603:Gm5286'
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm5286
Ensembl Gene ENSMUSG00000090268
Gene Namepredicted gene 5286
Accession Numbers
Is this an essential gene? Not available question?
Stock #IGL02603
Quality Score
Chromosomal Location94196714-94199802 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to T at 94198437 bp
Amino Acid Change Threonine to Serine at position 21 (T21S)
Ref Sequence ENSEMBL: ENSMUSP00000125267 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000159524]
Predicted Effect noncoding transcript
Transcript: ENSMUST00000159267
Predicted Effect possibly damaging
Transcript: ENSMUST00000159524
AA Change: T21S

PolyPhen 2 Score 0.532 (Sensitivity: 0.88; Specificity: 0.90)
SMART Domains Protein: ENSMUSP00000125267
Gene: ENSMUSG00000090268
AA Change: T21S

MATH 17 126 7.18e-6 SMART
BTB 184 283 8.21e-26 SMART
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 20 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Adgrv1 A G 13: 81,488,952 S3457P possibly damaging Het
Aipl1 A G 11: 72,036,700 I63T possibly damaging Het
Atp7b C T 8: 21,994,776 V1307M possibly damaging Het
Cdc20b T C 13: 113,078,755 S286P possibly damaging Het
Eif2ak4 G A 2: 118,450,326 R946H probably damaging Het
Fam98c A G 7: 29,154,448 S232P probably damaging Het
Glt1d1 G T 5: 127,632,345 R21L probably damaging Het
Gm5422 A G 10: 31,249,440 noncoding transcript Het
Haao T A 17: 83,835,541 D125V probably benign Het
Hipk1 A G 3: 103,750,272 V832A probably damaging Het
Lrrtm4 C A 6: 80,022,984 Q460K possibly damaging Het
Lyar A G 5: 38,234,061 N368S probably damaging Het
Lyst G A 13: 13,660,956 C1741Y probably benign Het
Lztr1 C A 16: 17,509,686 N84K possibly damaging Het
Ndufa8 C A 2: 36,044,458 C36F probably damaging Het
Olfr136 T A 17: 38,335,513 S119T probably damaging Het
Olfr739 T A 14: 50,425,200 V227E probably damaging Het
Psg19 A G 7: 18,792,768 S146P probably benign Het
Rbm12 C T 2: 156,095,560 probably benign Het
Rnf123 G A 9: 108,068,302 R390* probably null Het
Other mutations in Gm5286
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01590:Gm5286 APN 3 94198367 utr 5 prime probably benign
R7130:Gm5286 UTSW 3 94198527 missense probably damaging 1.00
R7209:Gm5286 UTSW 3 94198705 missense probably benign
R7595:Gm5286 UTSW 3 94198417 missense probably benign 0.15
R7661:Gm5286 UTSW 3 94198402 missense probably damaging 0.98
Posted On2015-04-16