Mutagenetix > Incidental Mutations

Incidental Mutation 'IGL02605:Lrrc8d'

300214

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Lrrc8d

Ensembl Gene

ENSMUSG00000046079

Gene Name

leucine rich repeat containing 8D

Synonyms

Lrrc5, 2810473G09Rik, 4930525N13Rik

Accession Numbers

Is this an essential gene?

Non essential (E-score: 0.000) question?

Stock #

IGL02605

Quality Score

Status

Chromosome

Chromosomal Location

105699969-105832436 bp(+) (GRCm38)

Type of Mutation

intron

DNA Base Change (assembly)

A to T at 105826817 bp

Zygosity

Heterozygous

Amino Acid Change

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000134605

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000140081

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 40 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abtb2	A	T	2: 103,717,257	Y992F	probably benign	Het
Adgrg6	T	A	10: 14,467,232	N324Y	probably damaging	Het
Ampd3	T	C	7: 110,795,758	F305L	probably benign	Het
Ankrd35	A	G	3: 96,681,072		probably null	Het
Api5	A	G	2: 94,429,719	I64T	possibly damaging	Het
Arhgap21	A	G	2: 20,855,588	I1165T	probably damaging	Het
Bdp1	T	C	13: 100,078,115		probably null	Het
Capn3	T	A	2: 120,496,037	I570N	probably damaging	Het
Catsperg2	T	C	7: 29,719,565	H232R	possibly damaging	Het
Clcn7	T	C	17: 25,146,818	L156P	possibly damaging	Het
Cpa3	C	A	3: 20,222,212	V286F	probably benign	Het
Csrnp3	G	A	2: 66,022,809	C527Y	probably damaging	Het
Dock5	A	T	14: 67,828,438	V372E	probably benign	Het
Elmo1	T	C	13: 20,605,202	L696P	probably damaging	Het
Fam91a1	T	C	15: 58,431,196		probably benign	Het
Gm12695	T	A	4: 96,762,751	D155V	probably null	Het
Hspa4l	A	G	3: 40,781,623	I559V	probably benign	Het
Kdm1a	G	T	4: 136,551,037		probably benign	Het
Minpp1	A	T	19: 32,498,415	Y316F	possibly damaging	Het
Neto2	T	C	8: 85,663,435		probably benign	Het
Nrxn2	T	A	19: 6,450,580	D277E	probably benign	Het
Ola1	A	G	2: 73,142,300		probably benign	Het
Olfr1298	A	G	2: 111,645,505	V164A	probably benign	Het
Olfr550	T	C	7: 102,579,395	I300T	probably damaging	Het
Olfr893	T	A	9: 38,209,236	M61K	probably damaging	Het
Pam	A	G	1: 97,840,339	V722A	possibly damaging	Het
Pfdn6	T	C	17: 33,939,103	Y90C	probably benign	Het
Pkhd1	T	A	1: 20,550,902	H844L	possibly damaging	Het
Plk5	G	A	10: 80,363,062	V422M	probably damaging	Het
Psmc1	G	T	12: 100,119,127	R249L	probably damaging	Het
Ptpro	C	T	6: 137,380,318	P269L	probably benign	Het
Ralgapa1	G	T	12: 55,712,665	H1480Q	possibly damaging	Het
Rars	G	A	11: 35,824,526		probably benign	Het
Rbm48	G	A	5: 3,590,600	R260C	possibly damaging	Het
Smarcc1	C	T	9: 110,222,000	H963Y	possibly damaging	Het
Spef2	T	C	15: 9,725,152	E230G	probably damaging	Het
Spg11	A	G	2: 122,092,260	S903P	probably benign	Het
Tas2r122	T	C	6: 132,711,609	Y107C	probably damaging	Het
Tpm3	C	A	3: 90,088,446	N204K	probably benign	Het
Wdr36	T	C	18: 32,851,991	I450T	possibly damaging	Het

Other mutations in Lrrc8d

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00765:Lrrc8d	APN	5	105811952	missense	possibly damaging	0.60
IGL01327:Lrrc8d	APN	5	105812265	missense	probably damaging	1.00
IGL02148:Lrrc8d	APN	5	105812387	missense	possibly damaging	0.92
IGL02228:Lrrc8d	APN	5	105811864	missense	probably benign	0.44
IGL02551:Lrrc8d	APN	5	105813548	missense	possibly damaging	0.78
BB009:Lrrc8d	UTSW	5	105813025	missense	probably damaging	1.00
BB019:Lrrc8d	UTSW	5	105813025	missense	probably damaging	1.00
R0415:Lrrc8d	UTSW	5	105811865	missense	probably damaging	1.00
R1424:Lrrc8d	UTSW	5	105826916	missense	unknown
R1754:Lrrc8d	UTSW	5	105812657	missense	probably benign
R3411:Lrrc8d	UTSW	5	105826706	intron	noncoding transcript
R3605:Lrrc8d	UTSW	5	105827007	missense	unknown
R3705:Lrrc8d	UTSW	5	105813475	missense	probably damaging	1.00
R3798:Lrrc8d	UTSW	5	105812489	missense	probably benign	0.12
R3951:Lrrc8d	UTSW	5	105814276	missense	probably benign	0.00
R4300:Lrrc8d	UTSW	5	105813740	missense	probably damaging	0.99
R4953:Lrrc8d	UTSW	5	105813368	missense	probably damaging	1.00
R5211:Lrrc8d	UTSW	5	105813740	missense	probably damaging	0.99
R5436:Lrrc8d	UTSW	5	105812552	missense	probably damaging	0.98
R5512:Lrrc8d	UTSW	5	105812784	missense	probably damaging	1.00
R5512:Lrrc8d	UTSW	5	105812785	missense	probably benign	0.00
R5514:Lrrc8d	UTSW	5	105812784	missense	probably damaging	1.00
R5514:Lrrc8d	UTSW	5	105812785	missense	probably benign	0.00
R5531:Lrrc8d	UTSW	5	105797670	intron	probably benign
R5929:Lrrc8d	UTSW	5	105812606	missense	probably damaging	0.98
R6063:Lrrc8d	UTSW	5	105812126	missense	probably benign	0.01
R6379:Lrrc8d	UTSW	5	105812809	missense	probably benign	0.08
R6431:Lrrc8d	UTSW	5	105811760	missense	probably damaging	1.00
R7127:Lrrc8d	UTSW	5	105812963	missense	probably damaging	1.00
R7682:Lrrc8d	UTSW	5	105812791	missense	probably damaging	1.00
R7821:Lrrc8d	UTSW	5	105812344	missense	probably damaging	1.00
R7932:Lrrc8d	UTSW	5	105813025	missense	probably damaging	1.00
R8528:Lrrc8d	UTSW	5	105812486
RF003:Lrrc8d	UTSW	5	105812641	missense	probably damaging	1.00
X0024:Lrrc8d	UTSW	5	105811745	missense	probably damaging	0.99

Posted On

2015-04-16