Incidental Mutation 'IGL02611:Psg29'
ID300479
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Psg29
Ensembl Gene ENSMUSG00000023159
Gene Namepregnancy-specific glycoprotein 29
Synonymscea17
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.054) question?
Stock #IGL02611
Quality Score
Status
Chromosome7
Chromosomal Location17203477-17215760 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) G to A at 17208791 bp
ZygosityHeterozygous
Amino Acid Change Arginine to Glutamine at position 239 (R239Q)
Ref Sequence ENSEMBL: ENSMUSP00000075320 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000075934]
Predicted Effect probably benign
Transcript: ENSMUST00000075934
AA Change: R239Q

PolyPhen 2 Score 0.147 (Sensitivity: 0.92; Specificity: 0.87)
SMART Domains Protein: ENSMUSP00000075320
Gene: ENSMUSG00000023159
AA Change: R239Q

DomainStartEndE-ValueType
IG 40 137 7.77e-1 SMART
IG 156 257 8.72e-4 SMART
IG 276 377 2.44e0 SMART
IGc2 393 457 3.06e-8 SMART
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 20 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Chac1 T A 2: 119,353,453 Y179N probably damaging Het
Cyp2c37 T G 19: 39,993,865 F103L probably benign Het
Dmp1 A T 5: 104,212,514 D352V probably damaging Het
Dpp8 T C 9: 65,055,793 I443T probably benign Het
Furin G A 7: 80,391,778 A544V probably benign Het
Galntl6 A G 8: 57,958,416 M260T probably damaging Het
Gm17654 G A 14: 43,579,005 T47I possibly damaging Het
Hadha A G 5: 30,128,943 probably benign Het
Itfg2 T A 6: 128,424,725 N30I probably damaging Het
Kntc1 T A 5: 123,812,065 L1977H probably damaging Het
Lats1 T C 10: 7,705,787 F779L possibly damaging Het
Ltbp4 T C 7: 27,310,655 Y1160C probably damaging Het
Mcm7 C A 5: 138,167,439 S401I probably damaging Het
Olfr659 A T 7: 104,671,407 D235V possibly damaging Het
Olfr694 G T 7: 106,688,789 T314K probably benign Het
Pcdh8 C T 14: 79,767,667 V876I probably benign Het
Pfpl T C 19: 12,430,283 S633P probably benign Het
St18 T A 1: 6,768,890 probably benign Het
Syt2 G A 1: 134,741,882 C87Y possibly damaging Het
Unc79 A G 12: 103,165,708 T2300A probably damaging Het
Other mutations in Psg29
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01020:Psg29 APN 7 17208732 missense probably benign 0.42
IGL01107:Psg29 APN 7 17204925 missense probably benign 0.01
IGL01348:Psg29 APN 7 17210673 missense probably benign 0.09
IGL01353:Psg29 APN 7 17205013 missense possibly damaging 0.54
IGL02546:Psg29 APN 7 17208782 missense probably damaging 1.00
IGL02982:Psg29 APN 7 17211707 missense probably damaging 0.98
IGL03072:Psg29 APN 7 17208794 missense probably benign 0.06
macular UTSW 7 17210535 missense probably benign 0.23
papular UTSW 7 17211912 makesense probably null
R1744:Psg29 UTSW 7 17210353 missense probably damaging 1.00
R2272:Psg29 UTSW 7 17210696 missense probably benign 0.19
R3054:Psg29 UTSW 7 17208802 missense probably benign 0.29
R3790:Psg29 UTSW 7 17205025 missense possibly damaging 0.71
R3963:Psg29 UTSW 7 17208585 missense probably benign 0.01
R4464:Psg29 UTSW 7 17210650 missense possibly damaging 0.61
R4740:Psg29 UTSW 7 17208533 missense probably benign 0.00
R4774:Psg29 UTSW 7 17210535 missense probably benign 0.23
R4902:Psg29 UTSW 7 17211912 makesense probably null
R4977:Psg29 UTSW 7 17208631 missense probably damaging 1.00
R5071:Psg29 UTSW 7 17211838 missense probably damaging 1.00
R5072:Psg29 UTSW 7 17211838 missense probably damaging 1.00
R5074:Psg29 UTSW 7 17211838 missense probably damaging 1.00
R5169:Psg29 UTSW 7 17211653 missense probably damaging 1.00
R5415:Psg29 UTSW 7 17211636 splice site probably null
R5729:Psg29 UTSW 7 17210534 missense probably damaging 0.98
R6023:Psg29 UTSW 7 17210512 missense possibly damaging 0.82
R6127:Psg29 UTSW 7 17211746 missense probably benign 0.00
R6900:Psg29 UTSW 7 17204932 nonsense probably null
R7142:Psg29 UTSW 7 17210621 missense probably damaging 1.00
R7297:Psg29 UTSW 7 17210691 nonsense probably null
R7448:Psg29 UTSW 7 17211723 missense possibly damaging 0.90
R7973:Psg29 UTSW 7 17210537 missense probably benign 0.03
R8027:Psg29 UTSW 7 17208640 missense possibly damaging 0.69
X0017:Psg29 UTSW 7 17210661 nonsense probably null
Posted On2015-04-16