Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02614:Vmn2r92'

300610

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn2r92

Ensembl Gene

ENSMUSG00000091350

Gene Name

vomeronasal 2, receptor 92

Synonyms

EG627111

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.101) question?

Stock #

IGL02614

Quality Score

Status

Chromosome

Chromosomal Location

18372192-18405440 bp(+) (GRCm39)

Type of Mutation

splice site

DNA Base Change (assembly)

T to C at 18387503 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000128685 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000169686]

AlphaFold

L7N2A4

Predicted Effect

probably benign
Transcript: ENSMUST00000169686

SMART Domains

Protein: ENSMUSP00000128685
Gene: ENSMUSG00000091350

Domain	Start	End	E-Value	Type
signal peptide	1	20	N/A	INTRINSIC
Pfam:ANF_receptor	83	463	4.7e-38	PFAM
Pfam:NCD3G	510	564	2.5e-19	PFAM
Pfam:7tm_3	597	832	1.1e-52	PFAM
low complexity region	843	855	N/A	INTRINSIC

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 35 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Aasdh	A	T	5: 77,044,215 (GRCm39)		probably benign	Het
Acadsb	A	G	7: 131,026,357 (GRCm39)	T67A	probably benign	Het
Aff2	A	G	X: 68,907,693 (GRCm39)	D1225G	possibly damaging	Het
Atp2a2	T	C	5: 122,627,366 (GRCm39)	D133G	probably benign	Het
Cacul1	A	T	19: 60,551,661 (GRCm39)	M187K	possibly damaging	Het
Celf4	A	G	18: 25,637,207 (GRCm39)	Y263H	probably damaging	Het
Cmbl	G	T	15: 31,589,830 (GRCm39)	V187F	probably damaging	Het
Epha1	T	C	6: 42,337,491 (GRCm39)	N896S	probably benign	Het
Fbxo27	G	A	7: 28,396,201 (GRCm39)		probably null	Het
Galnt16	T	C	12: 80,623,337 (GRCm39)	S166P	probably damaging	Het
Gm1110	A	G	9: 26,832,010 (GRCm39)	V47A	probably benign	Het
Gmnn	A	G	13: 24,944,137 (GRCm39)		probably benign	Het
Gpbp1	T	C	13: 111,573,007 (GRCm39)	I382V	probably benign	Het
Gpr87	C	A	3: 59,086,738 (GRCm39)	V256L	probably damaging	Het
Il4ra	C	A	7: 125,174,962 (GRCm39)	S390*	probably null	Het
Itprid1	A	T	6: 55,945,262 (GRCm39)	D661V	probably damaging	Het
Lrrc47	T	C	4: 154,103,392 (GRCm39)		probably null	Het
Lrriq4	A	T	3: 30,709,788 (GRCm39)	L362F	probably damaging	Het
Lrrtm4	A	T	6: 79,998,827 (GRCm39)	N79Y	probably benign	Het
Nr1i2	T	A	16: 38,074,118 (GRCm39)	H165L	probably damaging	Het
Or10g1b	T	C	14: 52,627,627 (GRCm39)	E201G	probably damaging	Het
Phf11a	T	A	14: 59,516,817 (GRCm39)	T214S	possibly damaging	Het
Prr14l	A	T	5: 32,987,887 (GRCm39)	I536K	possibly damaging	Het
Rpn1	T	A	6: 88,079,087 (GRCm39)	I510N	probably benign	Het
Sall4	A	T	2: 168,597,805 (GRCm39)	L20Q	probably null	Het
Sema3f	T	C	9: 107,559,710 (GRCm39)	E759G	probably benign	Het
Slc5a1	T	C	5: 33,311,945 (GRCm39)	S446P	probably benign	Het
Srrm1	G	A	4: 135,052,415 (GRCm39)	P658L	unknown	Het
Tcn2	C	A	11: 3,876,158 (GRCm39)	S90I	possibly damaging	Het
Ttn	T	C	2: 76,542,331 (GRCm39)	T31806A	possibly damaging	Het
Ubr1	T	C	2: 120,701,460 (GRCm39)		probably benign	Het
Vac14	T	G	8: 111,361,750 (GRCm39)	L214R	probably damaging	Het
Vmn2r58	T	C	7: 41,486,553 (GRCm39)	K781E	probably damaging	Het
Zfp518a	G	A	19: 40,903,061 (GRCm39)	G997R	probably damaging	Het
Zfp609	G	A	9: 65,610,072 (GRCm39)	P964S	probably damaging	Het

Other mutations in Vmn2r92

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01591:Vmn2r92	APN	17	18,405,423 (GRCm39)	missense	unknown
IGL01758:Vmn2r92	APN	17	18,372,275 (GRCm39)	nonsense	probably null
IGL03095:Vmn2r92	APN	17	18,386,972 (GRCm39)	missense	possibly damaging	0.55
IGL03403:Vmn2r92	APN	17	18,387,114 (GRCm39)	missense	probably damaging	0.98
R0133:Vmn2r92	UTSW	17	18,388,219 (GRCm39)	missense	probably damaging	1.00
R0225:Vmn2r92	UTSW	17	18,388,219 (GRCm39)	missense	probably damaging	1.00
R0227:Vmn2r92	UTSW	17	18,388,219 (GRCm39)	missense	probably damaging	1.00
R0265:Vmn2r92	UTSW	17	18,388,219 (GRCm39)	missense	probably damaging	1.00
R0266:Vmn2r92	UTSW	17	18,388,219 (GRCm39)	missense	probably damaging	1.00
R0267:Vmn2r92	UTSW	17	18,388,219 (GRCm39)	missense	probably damaging	1.00
R0420:Vmn2r92	UTSW	17	18,389,183 (GRCm39)	missense	probably benign	0.01
R0426:Vmn2r92	UTSW	17	18,388,219 (GRCm39)	missense	probably damaging	1.00
R0494:Vmn2r92	UTSW	17	18,388,219 (GRCm39)	missense	probably damaging	1.00
R1253:Vmn2r92	UTSW	17	18,387,028 (GRCm39)	missense	probably benign	0.08
R1497:Vmn2r92	UTSW	17	18,387,625 (GRCm39)	missense	probably benign	0.02
R1571:Vmn2r92	UTSW	17	18,372,352 (GRCm39)	missense	probably damaging	0.96
R1656:Vmn2r92	UTSW	17	18,372,198 (GRCm39)	missense	probably benign
R1816:Vmn2r92	UTSW	17	18,386,939 (GRCm39)	missense	probably damaging	0.98
R2229:Vmn2r92	UTSW	17	18,387,654 (GRCm39)	missense	probably benign	0.01
R2909:Vmn2r92	UTSW	17	18,405,377 (GRCm39)	missense	possibly damaging	0.89
R3694:Vmn2r92	UTSW	17	18,372,205 (GRCm39)	nonsense	probably null
R4207:Vmn2r92	UTSW	17	18,404,523 (GRCm39)	missense	possibly damaging	0.62
R4548:Vmn2r92	UTSW	17	18,391,578 (GRCm39)	missense	probably benign
R4612:Vmn2r92	UTSW	17	18,387,132 (GRCm39)	missense	probably benign	0.25
R4742:Vmn2r92	UTSW	17	18,387,119 (GRCm39)	missense	probably benign	0.06
R4824:Vmn2r92	UTSW	17	18,372,183 (GRCm39)	utr 5 prime	probably benign
R4865:Vmn2r92	UTSW	17	18,387,634 (GRCm39)	missense	probably benign	0.16
R4900:Vmn2r92	UTSW	17	18,404,605 (GRCm39)	missense	probably benign	0.27
R5084:Vmn2r92	UTSW	17	18,405,439 (GRCm39)	makesense	probably null
R5140:Vmn2r92	UTSW	17	18,372,312 (GRCm39)	missense	probably benign	0.07
R5995:Vmn2r92	UTSW	17	18,389,213 (GRCm39)	critical splice donor site	probably null
R6045:Vmn2r92	UTSW	17	18,388,305 (GRCm39)	critical splice donor site	probably null
R6269:Vmn2r92	UTSW	17	18,387,036 (GRCm39)	missense	probably benign	0.01
R6877:Vmn2r92	UTSW	17	18,389,084 (GRCm39)	missense	probably damaging	1.00
R7151:Vmn2r92	UTSW	17	18,387,005 (GRCm39)	missense	probably benign	0.01
R7260:Vmn2r92	UTSW	17	18,387,138 (GRCm39)	missense	probably damaging	1.00
R7344:Vmn2r92	UTSW	17	18,387,513 (GRCm39)	missense	probably benign	0.01
R7514:Vmn2r92	UTSW	17	18,391,533 (GRCm39)	missense	probably damaging	1.00
R7576:Vmn2r92	UTSW	17	18,387,621 (GRCm39)	missense	probably benign	0.01
R7584:Vmn2r92	UTSW	17	18,387,028 (GRCm39)	missense	probably benign	0.08
R7912:Vmn2r92	UTSW	17	18,404,970 (GRCm39)	missense	possibly damaging	0.91
R7941:Vmn2r92	UTSW	17	18,405,099 (GRCm39)	missense	possibly damaging	0.89
R8178:Vmn2r92	UTSW	17	18,386,988 (GRCm39)	missense	possibly damaging	0.69
R8238:Vmn2r92	UTSW	17	18,405,278 (GRCm39)	missense	probably benign	0.00
R8239:Vmn2r92	UTSW	17	18,405,278 (GRCm39)	missense	probably benign	0.00
R8252:Vmn2r92	UTSW	17	18,387,134 (GRCm39)	missense	probably damaging	1.00
R8322:Vmn2r92	UTSW	17	18,386,886 (GRCm39)	missense	probably damaging	0.99
R8355:Vmn2r92	UTSW	17	18,405,061 (GRCm39)	missense	probably damaging	0.99
R9399:Vmn2r92	UTSW	17	18,389,137 (GRCm39)	missense	probably benign	0.29
R9639:Vmn2r92	UTSW	17	18,372,352 (GRCm39)	missense	probably damaging	0.96
R9747:Vmn2r92	UTSW	17	18,405,201 (GRCm39)	missense	possibly damaging	0.66
R9773:Vmn2r92	UTSW	17	18,386,949 (GRCm39)	missense	probably damaging	1.00
X0066:Vmn2r92	UTSW	17	18,405,157 (GRCm39)	missense	probably damaging	1.00
Z1177:Vmn2r92	UTSW	17	18,404,795 (GRCm39)	missense	probably damaging	0.96

Posted On

2015-04-16