Incidental Mutation 'IGL02621:Vmn1r168'
ID300853
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Vmn1r168
Ensembl Gene ENSMUSG00000074291
Gene Namevomeronasal 1 receptor 168
SynonymsGm10659
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.112) question?
Stock #IGL02621
Quality Score
Status
Chromosome7
Chromosomal Location23540720-23541649 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to T at 23541355 bp
ZygosityHeterozygous
Amino Acid Change Arginine to Serine at position 212 (R212S)
Ref Sequence ENSEMBL: ENSMUSP00000096301 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000098704]
Predicted Effect probably damaging
Transcript: ENSMUST00000098704
AA Change: R212S

PolyPhen 2 Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
SMART Domains Protein: ENSMUSP00000096301
Gene: ENSMUSG00000074291
AA Change: R212S

DomainStartEndE-ValueType
Pfam:TAS2R 8 296 1.1e-12 PFAM
Pfam:V1R 41 295 2.5e-14 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 32 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
1110002L01Rik C A 12: 3,426,688 probably benign Het
2210408I21Rik T C 13: 77,260,031 I159T possibly damaging Het
4932438A13Rik T A 3: 37,041,484 probably benign Het
Agpat3 T A 10: 78,285,066 I93F probably damaging Het
AI481877 A T 4: 59,062,668 W863R probably damaging Het
Armc8 T C 9: 99,527,069 probably benign Het
Atr G A 9: 95,908,400 A1598T probably benign Het
Clk1 T C 1: 58,414,455 D324G probably damaging Het
Cntnap4 A T 8: 112,810,723 D742V probably damaging Het
Esrrb A G 12: 86,421,961 N16S probably benign Het
Grm1 A T 10: 10,689,011 Y1184* probably null Het
Hint1 G T 11: 54,870,185 probably benign Het
Itch A T 2: 155,172,584 probably null Het
Lmod3 T C 6: 97,238,835 probably benign Het
Map3k4 C A 17: 12,264,013 A606S probably damaging Het
Mapk4 A T 18: 73,970,275 S54R probably damaging Het
Megf11 A G 9: 64,693,932 D807G probably benign Het
Mgat5 A G 1: 127,397,589 T398A possibly damaging Het
Nme8 T G 13: 19,675,648 K28N probably damaging Het
Pamr1 A G 2: 102,634,343 N279S probably benign Het
Pcca A T 14: 122,684,979 D384V probably damaging Het
Prkag1 A T 15: 98,814,028 I239N probably damaging Het
Psme4 A G 11: 30,848,131 T1375A probably benign Het
Ptk2 A C 15: 73,206,145 L1024R probably damaging Het
Rere G A 4: 150,613,812 probably benign Het
Scn2a A G 2: 65,748,879 probably benign Het
Sema5a T A 15: 32,538,656 probably benign Het
Slc9a1 T A 4: 133,370,568 W9R probably benign Het
Slco1a5 T A 6: 142,242,015 M533L probably benign Het
Ttll4 T A 1: 74,687,484 S720T probably damaging Het
Vmn2r114 T C 17: 23,310,520 I203V probably damaging Het
Wdr38 A T 2: 38,998,412 N7I probably damaging Het
Other mutations in Vmn1r168
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01761:Vmn1r168 APN 7 23541645 missense possibly damaging 0.73
IGL02650:Vmn1r168 APN 7 23541491 missense probably benign 0.13
PIT4466001:Vmn1r168 UTSW 7 23540996 missense probably damaging 1.00
R0320:Vmn1r168 UTSW 7 23541342 missense probably benign 0.12
R1595:Vmn1r168 UTSW 7 23541195 missense probably damaging 1.00
R1618:Vmn1r168 UTSW 7 23541300 missense probably benign 0.02
R1808:Vmn1r168 UTSW 7 23540759 missense probably benign 0.05
R2418:Vmn1r168 UTSW 7 23541399 missense probably benign 0.05
R2419:Vmn1r168 UTSW 7 23541399 missense probably benign 0.05
R4846:Vmn1r168 UTSW 7 23541065 missense probably damaging 1.00
R4864:Vmn1r168 UTSW 7 23541482 missense probably damaging 0.98
R5269:Vmn1r168 UTSW 7 23541414 missense probably benign 0.40
R6265:Vmn1r168 UTSW 7 23541536 missense probably benign
R6353:Vmn1r168 UTSW 7 23541519 missense probably benign 0.02
R6768:Vmn1r168 UTSW 7 23541035 missense probably damaging 1.00
R6921:Vmn1r168 UTSW 7 23540898 missense probably damaging 1.00
R8247:Vmn1r168 UTSW 7 23541062 missense possibly damaging 0.61
Posted On2015-04-16