Incidental Mutation 'IGL02627:Vmn1r30'
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ID301150
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Vmn1r30
Ensembl Gene ENSMUSG00000095670
Gene Namevomeronasal 1 receptor 30
SynonymsV1rc9, V1rc22
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.090) question?
Stock #IGL02627
Quality Score
Status
Chromosome6
Chromosomal Location58434159-58443385 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) T to A at 58435761 bp
ZygosityHeterozygous
Amino Acid Change Threonine to Serine at position 29 (T29S)
Ref Sequence ENSEMBL: ENSMUSP00000154098 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000078890] [ENSMUST00000226334] [ENSMUST00000227466] [ENSMUST00000228577] [ENSMUST00000228635]
Predicted Effect probably benign
Transcript: ENSMUST00000078890
AA Change: T29S

PolyPhen 2 Score 0.082 (Sensitivity: 0.93; Specificity: 0.85)
SMART Domains Protein: ENSMUSP00000087336
Gene: ENSMUSG00000095670
AA Change: T29S

DomainStartEndE-ValueType
Pfam:V1R 29 293 4.8e-53 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000203463
Predicted Effect probably benign
Transcript: ENSMUST00000226334
AA Change: T29S

PolyPhen 2 Score 0.082 (Sensitivity: 0.93; Specificity: 0.85)
Predicted Effect probably benign
Transcript: ENSMUST00000227466
AA Change: T29S

PolyPhen 2 Score 0.082 (Sensitivity: 0.93; Specificity: 0.85)
Predicted Effect probably benign
Transcript: ENSMUST00000228577
AA Change: T29S

PolyPhen 2 Score 0.082 (Sensitivity: 0.93; Specificity: 0.85)
Predicted Effect probably benign
Transcript: ENSMUST00000228635
AA Change: T29S

PolyPhen 2 Score 0.082 (Sensitivity: 0.93; Specificity: 0.85)
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 28 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
1700001O22Rik T A 2: 30,795,765 K353M probably damaging Het
2610301B20Rik G A 4: 10,898,039 C207Y probably damaging Het
Arhgap32 T C 9: 32,246,006 Y100H probably damaging Het
Cdc45 C T 16: 18,798,729 M200I probably benign Het
Ckap5 A T 2: 91,576,021 N752I probably damaging Het
Dgkz T A 2: 91,938,710 probably benign Het
Egfr T A 11: 16,869,346 V292E probably damaging Het
Gnb3 T C 6: 124,834,715 T329A probably damaging Het
Igkv3-2 A T 6: 70,698,826 T40S probably damaging Het
Kcnq2 T C 2: 181,082,327 probably benign Het
Mbip T C 12: 56,335,805 Q292R probably benign Het
Mgat5b T C 11: 116,983,616 Y625H probably damaging Het
Ms4a4d A T 19: 11,548,623 E40D probably damaging Het
Naip1 T C 13: 100,425,648 E1003G possibly damaging Het
Ncf2 G A 1: 152,811,008 probably benign Het
Nfkbiz A G 16: 55,816,351 V529A probably damaging Het
Osr2 A G 15: 35,300,454 N52S possibly damaging Het
Prag1 A G 8: 36,139,439 D778G possibly damaging Het
Rsl1d1 G T 16: 11,194,551 A337E possibly damaging Het
Sall3 A T 18: 80,972,361 L784Q possibly damaging Het
Spen A G 4: 141,473,015 I2744T probably damaging Het
Tfip11 A C 5: 112,329,813 S145R possibly damaging Het
Tonsl T C 15: 76,634,095 D559G probably damaging Het
Trmt5 A T 12: 73,281,455 S325T probably damaging Het
Ubr1 A T 2: 120,940,991 V472D probably damaging Het
Vps29 T C 5: 122,362,845 S158P probably benign Het
Wdr82 T C 9: 106,176,687 V79A possibly damaging Het
Wfdc16 T A 2: 164,638,463 E37D possibly damaging Het
Other mutations in Vmn1r30
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01657:Vmn1r30 APN 6 58435634 missense probably benign 0.01
IGL02432:Vmn1r30 APN 6 58435670 missense probably benign 0.04
IGL02870:Vmn1r30 APN 6 58435370 missense probably benign 0.01
R0360:Vmn1r30 UTSW 6 58435277 missense probably benign 0.03
R1071:Vmn1r30 UTSW 6 58435828 missense possibly damaging 0.93
R1335:Vmn1r30 UTSW 6 58435095 missense probably damaging 1.00
R1888:Vmn1r30 UTSW 6 58435490 missense possibly damaging 0.93
R1888:Vmn1r30 UTSW 6 58435490 missense possibly damaging 0.93
R2483:Vmn1r30 UTSW 6 58435452 missense probably benign 0.02
R3622:Vmn1r30 UTSW 6 58435452 missense probably benign 0.02
R3623:Vmn1r30 UTSW 6 58435452 missense probably benign 0.02
R3624:Vmn1r30 UTSW 6 58435452 missense probably benign 0.02
R3744:Vmn1r30 UTSW 6 58435819 nonsense probably null
R3762:Vmn1r30 UTSW 6 58435293 missense probably benign 0.20
R4483:Vmn1r30 UTSW 6 58435133 missense probably damaging 1.00
R4484:Vmn1r30 UTSW 6 58435133 missense probably damaging 1.00
R5160:Vmn1r30 UTSW 6 58435383 missense probably benign 0.03
R5408:Vmn1r30 UTSW 6 58435044 missense probably benign 0.03
R5461:Vmn1r30 UTSW 6 58435774 nonsense probably null
R5888:Vmn1r30 UTSW 6 58435565 missense possibly damaging 0.94
R7068:Vmn1r30 UTSW 6 58435010 missense possibly damaging 0.94
R7490:Vmn1r30 UTSW 6 58435229 missense possibly damaging 0.80
R7680:Vmn1r30 UTSW 6 58435299 nonsense probably null
R7751:Vmn1r30 UTSW 6 58435412 missense probably benign 0.03
R8516:Vmn1r30 UTSW 6 58435124 missense probably damaging 0.96
Posted On2015-04-16