Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02629:Tas2r113'

301208

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Tas2r113

Ensembl Gene

ENSMUSG00000056926

Gene Name

taste receptor, type 2, member 113

Synonyms

T2R13, mGR13, Tas2r13, mt2r58

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.051) question?

Stock #

IGL02629

Quality Score

Status

Chromosome

Chromosomal Location

132869974-132870903 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 132870299 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Leucine to Proline at position 109 (L109P)

Ref Sequence

ENSEMBL: ENSMUSP00000078044 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000079035]

AlphaFold

Q7M711

Predicted Effect

probably damaging
Transcript: ENSMUST00000079035
AA Change: L109P

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000078044
Gene: ENSMUSG00000056926
AA Change: L109P

Domain	Start	End	E-Value	Type
Pfam:TAS2R	1	301	9.4e-78	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 50 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700017N19Rik	T	C	10: 100,445,006 (GRCm39)		probably benign	Het
Aadacl3	A	G	4: 144,190,199 (GRCm39)	I34T	possibly damaging	Het
Acan	T	A	7: 78,761,727 (GRCm39)	I1979N	possibly damaging	Het
Ankrd27	A	G	7: 35,325,121 (GRCm39)	D701G	probably benign	Het
Arhgap31	C	T	16: 38,429,526 (GRCm39)	G450S	probably benign	Het
Braf	T	C	6: 39,665,233 (GRCm39)	E45G	possibly damaging	Het
Btnl6	C	T	17: 34,733,442 (GRCm39)	V178M	probably damaging	Het
Capg	A	T	6: 72,532,737 (GRCm39)	Q67L	probably benign	Het
Carmil3	A	G	14: 55,736,525 (GRCm39)	N663S	probably damaging	Het
Casz1	T	A	4: 149,028,848 (GRCm39)	S1098T	probably benign	Het
Cd55b	A	T	1: 130,347,535 (GRCm39)		probably benign	Het
Cdc45	C	T	16: 18,617,479 (GRCm39)	M200I	probably benign	Het
Cenpf	A	G	1: 189,384,531 (GRCm39)	L2583P	probably damaging	Het
Clec4a1	A	C	6: 122,909,106 (GRCm39)		probably null	Het
Corin	T	C	5: 72,490,016 (GRCm39)	N653S	probably damaging	Het
Dhx36	T	C	3: 62,414,155 (GRCm39)	E69G	probably benign	Het
Dpy19l1	C	A	9: 24,350,009 (GRCm39)		probably benign	Het
Fam184a	T	C	10: 53,574,907 (GRCm39)	N234S	possibly damaging	Het
Foxg1	A	G	12: 49,432,331 (GRCm39)	S355G	probably benign	Het
Fsd1l	T	C	4: 53,686,417 (GRCm39)	S277P	probably damaging	Het
Hadh	T	A	3: 131,029,284 (GRCm39)	D245V	probably damaging	Het
Jag2	G	A	12: 112,878,134 (GRCm39)		probably benign	Het
Klhl18	A	T	9: 110,259,006 (GRCm39)		probably benign	Het
Lmx1a	G	T	1: 167,672,192 (GRCm39)		probably benign	Het
Mcoln2	A	G	3: 145,875,799 (GRCm39)	Y89C	probably benign	Het
Mug1	A	T	6: 121,817,024 (GRCm39)	Y31F	possibly damaging	Het
Ndufb5	A	G	3: 32,791,348 (GRCm39)	T32A	probably benign	Het
Nub1	C	T	5: 24,908,462 (GRCm39)	H404Y	possibly damaging	Het
Nudt6	A	G	3: 37,459,320 (GRCm39)	Y222H	probably benign	Het
Or4x6	A	T	2: 89,949,201 (GRCm39)	L247*	probably null	Het
Pla2g4c	A	T	7: 13,069,302 (GRCm39)	R159*	probably null	Het
Pnpla7	A	G	2: 24,940,957 (GRCm39)	D1103G	probably damaging	Het
Pof1b	T	G	X: 111,554,934 (GRCm39)		probably benign	Het
Prrg2	C	T	7: 44,706,166 (GRCm39)		probably null	Het
Rab3gap1	A	G	1: 127,837,600 (GRCm39)	T221A	probably benign	Het
Rfx7	A	G	9: 72,526,541 (GRCm39)	N1244D	probably damaging	Het
Rnf123	G	A	9: 107,945,501 (GRCm39)	R390*	probably null	Het
Rnf123	A	T	9: 107,947,988 (GRCm39)		probably benign	Het
Rnf44	T	G	13: 54,830,875 (GRCm39)	Q207P	possibly damaging	Het
Serpina3g	A	G	12: 104,207,437 (GRCm39)	D200G	probably damaging	Het
Slc5a4a	T	A	10: 75,983,413 (GRCm39)	S17T	unknown	Het
Smc4	G	T	3: 68,933,206 (GRCm39)	C609F	probably damaging	Het
Sync	T	C	4: 129,187,744 (GRCm39)	F259L	probably damaging	Het
Tjp2	C	A	19: 24,099,743 (GRCm39)		probably benign	Het
Tmem30a	C	A	9: 79,683,531 (GRCm39)		probably benign	Het
Unc80	T	C	1: 66,522,476 (GRCm39)	V226A	possibly damaging	Het
Upk2	A	T	9: 44,365,436 (GRCm39)	L44Q	probably damaging	Het
Usp42	T	C	5: 143,708,909 (GRCm39)	Y203C	possibly damaging	Het
Vmn1r28	A	T	6: 58,242,801 (GRCm39)	I215F	probably benign	Het
Zswim2	A	G	2: 83,755,553 (GRCm39)	V116A	possibly damaging	Het

Other mutations in Tas2r113

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00858:Tas2r113	APN	6	132,870,115 (GRCm39)	missense	probably benign	0.01
IGL01118:Tas2r113	APN	6	132,870,278 (GRCm39)	missense	probably benign	0.00
IGL01366:Tas2r113	APN	6	132,870,760 (GRCm39)	missense	probably benign	0.06
IGL01955:Tas2r113	APN	6	132,870,817 (GRCm39)	missense	probably benign
IGL02681:Tas2r113	APN	6	132,870,330 (GRCm39)	missense	probably damaging	1.00
IGL02883:Tas2r113	APN	6	132,870,382 (GRCm39)	missense	probably damaging	1.00
R0002:Tas2r113	UTSW	6	132,870,742 (GRCm39)	missense	probably benign	0.21
R0309:Tas2r113	UTSW	6	132,870,341 (GRCm39)	missense	probably damaging	1.00
R1700:Tas2r113	UTSW	6	132,870,755 (GRCm39)	missense	possibly damaging	0.92
R1748:Tas2r113	UTSW	6	132,870,695 (GRCm39)	missense	probably damaging	0.98
R1854:Tas2r113	UTSW	6	132,870,292 (GRCm39)	missense	probably damaging	1.00
R1974:Tas2r113	UTSW	6	132,870,796 (GRCm39)	missense	probably benign	0.00
R4697:Tas2r113	UTSW	6	132,870,479 (GRCm39)	missense	probably benign	0.04
R4798:Tas2r113	UTSW	6	132,870,670 (GRCm39)	missense	possibly damaging	0.69
R4816:Tas2r113	UTSW	6	132,870,745 (GRCm39)	missense	probably benign	0.09
R4906:Tas2r113	UTSW	6	132,870,521 (GRCm39)	missense	possibly damaging	0.69
R6005:Tas2r113	UTSW	6	132,870,659 (GRCm39)	missense	probably benign	0.02
R6012:Tas2r113	UTSW	6	132,870,644 (GRCm39)	missense	probably damaging	1.00
R6107:Tas2r113	UTSW	6	132,869,977 (GRCm39)	missense	probably damaging	1.00
R6603:Tas2r113	UTSW	6	132,870,421 (GRCm39)	missense	probably benign	0.01
R7263:Tas2r113	UTSW	6	132,870,539 (GRCm39)	missense	possibly damaging	0.90
R7434:Tas2r113	UTSW	6	132,870,272 (GRCm39)	missense	probably benign	0.03
R7759:Tas2r113	UTSW	6	132,870,890 (GRCm39)	missense	possibly damaging	0.85
R8803:Tas2r113	UTSW	6	132,870,104 (GRCm39)	missense	possibly damaging	0.79
R9104:Tas2r113	UTSW	6	132,870,116 (GRCm39)	missense	probably benign	0.08
X0022:Tas2r113	UTSW	6	132,870,259 (GRCm39)	missense	probably damaging	0.98

Posted On

2015-04-16