Incidental Mutation 'IGL02630:Ube2dnl1'
ID301237
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Ube2dnl1
Ensembl Gene ENSMUSG00000050435
Gene Nameubiquitin-conjugating enzyme E2D N-terminal like 1
SynonymsEG237009, Ube2dnl
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.101) question?
Stock #IGL02630
Quality Score
Status
ChromosomeX
Chromosomal Location114905012-114905941 bp(+) (GRCm38)
Type of Mutationnonsense
DNA Base Change (assembly) T to A at 114905786 bp
ZygosityHeterozygous
Amino Acid Change Cysteine to Stop codon at position 119 (C119*)
Ref Sequence ENSEMBL: ENSMUSP00000060423 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000059509] [ENSMUST00000062695]
Predicted Effect probably null
Transcript: ENSMUST00000059509
AA Change: C119*
SMART Domains Protein: ENSMUSP00000060423
Gene: ENSMUSG00000050435
AA Change: C119*

DomainStartEndE-ValueType
UBCc 12 155 7.29e-71 SMART
Predicted Effect probably benign
Transcript: ENSMUST00000062695
SMART Domains Protein: ENSMUSP00000059077
Gene: ENSMUSG00000047079

DomainStartEndE-ValueType
UBCc 12 155 8.06e-73 SMART
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 48 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Ahnak T A 19: 9,012,077 V3575E probably damaging Het
Arfgef3 G A 10: 18,661,392 probably benign Het
Arhgap23 A G 11: 97,454,297 T631A probably benign Het
Chka T A 19: 3,892,112 H355Q possibly damaging Het
Ctsj C T 13: 61,001,400 A277T probably damaging Het
Ddx49 T C 8: 70,301,018 D67G probably damaging Het
Dennd4b T C 3: 90,272,977 S716P probably benign Het
Enpp5 G T 17: 44,082,875 D321Y probably damaging Het
Espl1 A G 15: 102,296,818 E17G probably benign Het
Fam161b G A 12: 84,353,914 P428L probably benign Het
Fbxw7 T C 3: 84,965,279 L256S probably damaging Het
Fgfr2 G T 7: 130,228,795 probably null Het
Foxred2 C T 15: 77,947,162 V484I probably benign Het
Gm4744 T A 6: 40,950,469 probably benign Het
Gm5724 T C 6: 141,723,110 Y532C probably damaging Het
Hipk2 T C 6: 38,818,521 N271S possibly damaging Het
Hist1h3a C T 13: 23,762,248 V36M probably benign Het
Ifna1 A G 4: 88,850,259 D58G possibly damaging Het
Igkv4-80 A T 6: 69,016,696 Y70* probably null Het
Ivns1abp G A 1: 151,359,635 R218H probably damaging Het
Kng1 A T 16: 23,079,845 probably benign Het
Lars T C 18: 42,257,169 D11G probably damaging Het
Lgals12 T C 19: 7,601,242 probably benign Het
Lpar4 T A X: 106,931,211 F334I probably benign Het
Muc5b G A 7: 141,863,231 G3305S probably benign Het
Nalcn T C 14: 123,317,879 D864G probably benign Het
Ndor1 T C 2: 25,255,287 E22G probably damaging Het
Nt5c2 T A 19: 46,924,310 M69L probably benign Het
Olfr1054 T C 2: 86,332,868 I163V probably benign Het
Olfr599 A C 7: 103,338,429 Y125S probably damaging Het
Pde12 A T 14: 26,666,397 H455Q probably damaging Het
Pdia6 A G 12: 17,274,421 H91R probably benign Het
Pdk4 A T 6: 5,491,671 I179K possibly damaging Het
Prl2c1 T C 13: 27,857,497 probably benign Het
Rasgrf2 C T 13: 92,131,392 E35K probably damaging Het
Rnf123 G A 9: 108,068,302 R390* probably null Het
Sash1 T A 10: 8,744,535 M454L probably benign Het
Secisbp2 C A 13: 51,678,906 T608K possibly damaging Het
Slmap A G 14: 26,422,431 V750A possibly damaging Het
Spaca6 T A 17: 17,831,089 L9Q probably damaging Het
Sycp1 T C 3: 102,878,764 probably benign Het
Sycp2 A T 2: 178,401,919 D131E probably damaging Het
Tc2n A T 12: 101,693,145 D176E probably damaging Het
Thoc7 T C 14: 13,953,154 I83V probably damaging Het
Trank1 T C 9: 111,373,075 V1590A possibly damaging Het
Tyrp1 T C 4: 80,840,757 V289A possibly damaging Het
Vmn1r191 T A 13: 22,179,261 I108F possibly damaging Het
Zfp710 T A 7: 80,082,041 I322N probably damaging Het
Other mutations in Ube2dnl1
AlleleSourceChrCoordTypePredicted EffectPPH Score
R4795:Ube2dnl1 UTSW X 114905785 missense possibly damaging 0.62
Z1177:Ube2dnl1 UTSW X 114905449 missense probably benign 0.21
Z1177:Ube2dnl1 UTSW X 114905452 missense probably benign
Posted On2015-04-16