Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02631:V1rd19'

301284

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

V1rd19

Ensembl Gene

ENSMUSG00000092456

Gene Name

vomeronasal 1 receptor, D19

Synonyms

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.063) question?

Stock #

IGL02631

Quality Score

Status

Chromosome

Chromosomal Location

23702536-23703453 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 23702825 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Leucine to Proline at position 97 (L97P)

Ref Sequence

ENSEMBL: ENSMUSP00000133284 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000173571]

AlphaFold

Q3KNP5

Predicted Effect

probably damaging
Transcript: ENSMUST00000173571
AA Change: L97P

PolyPhen 2 Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)

SMART Domains

Protein: ENSMUSP00000133284
Gene: ENSMUSG00000092456
AA Change: L97P

Domain	Start	End	E-Value	Type
Pfam:TAS2R	8	296	1e-9	PFAM
Pfam:V1R	42	295	5.9e-13	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 43 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Atp2b2	A	G	6: 113,725,506 (GRCm39)	S1242P	probably damaging	Het
Bglap	A	T	3: 88,290,987 (GRCm39)	Y81*	probably null	Het
Ccdc83	T	C	7: 89,893,277 (GRCm39)	D160G	possibly damaging	Het
Cep97	A	T	16: 55,742,541 (GRCm39)	C135*	probably null	Het
Cog1	C	T	11: 113,547,304 (GRCm39)	Q633*	probably null	Het
Cyp4f40	A	T	17: 32,894,609 (GRCm39)		probably benign	Het
Dennd2c	T	A	3: 103,063,387 (GRCm39)	M608K	possibly damaging	Het
Enpp1	A	G	10: 24,517,859 (GRCm39)	S855P	probably damaging	Het
Eprs1	T	C	1: 185,160,095 (GRCm39)	I1457T	probably damaging	Het
Fam149b	G	A	14: 20,425,614 (GRCm39)	V300M	probably damaging	Het
Fcgbp	T	A	7: 27,784,723 (GRCm39)	L261Q	probably damaging	Het
Flt1	G	T	5: 147,610,384 (GRCm39)	S413*	probably null	Het
Flt3	T	G	5: 147,281,362 (GRCm39)	D790A	probably damaging	Het
Gpat2	A	G	2: 127,276,152 (GRCm39)		probably benign	Het
Gpr151	T	C	18: 42,711,835 (GRCm39)	K281R	probably benign	Het
Hoxa5	G	A	6: 52,180,790 (GRCm39)	R181C	probably damaging	Het
Irx4	C	T	13: 73,416,596 (GRCm39)	R331W	probably damaging	Het
Lmo2	T	C	2: 103,811,432 (GRCm39)	I155T	probably benign	Het
Nbeal2	G	A	9: 110,459,276 (GRCm39)	R1944C	probably damaging	Het
Obp2b	A	G	2: 25,629,255 (GRCm39)	N141S	probably damaging	Het
Or4c10b	T	A	2: 89,711,599 (GRCm39)	V143E	possibly damaging	Het
Or4c3d	T	A	2: 89,881,786 (GRCm39)	N294I	probably damaging	Het
Papss2	T	A	19: 32,611,404 (GRCm39)		probably benign	Het
Rapgef2	A	T	3: 78,990,533 (GRCm39)	M915K	possibly damaging	Het
Raver2	A	C	4: 100,953,499 (GRCm39)	D89A	probably damaging	Het
Rnf123	G	A	9: 107,945,501 (GRCm39)	R390*	probably null	Het
Setd2	A	G	9: 110,379,644 (GRCm39)	D1153G	possibly damaging	Het
Slc25a12	C	T	2: 71,127,086 (GRCm39)	G365E	possibly damaging	Het
Slc35e4	A	C	11: 3,857,729 (GRCm39)	V292G	probably damaging	Het
Slc36a4	T	C	9: 15,638,237 (GRCm39)	V221A	probably damaging	Het
Slc7a14	C	A	3: 31,292,827 (GRCm39)	A153S	probably damaging	Het
Smc1b	T	C	15: 84,991,204 (GRCm39)	D658G	probably damaging	Het
Srrm1	G	A	4: 135,052,415 (GRCm39)	P658L	unknown	Het
Tab3	A	G	X: 84,658,139 (GRCm39)	N222S	probably benign	Het
Tdrd6	T	A	17: 43,937,110 (GRCm39)	T1313S	probably damaging	Het
Tnfrsf1b	A	T	4: 144,951,398 (GRCm39)	C181S	probably damaging	Het
Trdn	A	T	10: 33,239,972 (GRCm39)		probably null	Het
Trip12	A	T	1: 84,743,729 (GRCm39)	V526E	possibly damaging	Het
Trps1	T	C	15: 50,709,417 (GRCm39)	D311G	probably damaging	Het
Ttf1	A	G	2: 28,959,912 (GRCm39)	I507V	probably damaging	Het
Unc80	A	C	1: 66,569,222 (GRCm39)	D959A	probably damaging	Het
Unc93b1	T	C	19: 3,992,026 (GRCm39)		probably benign	Het
Utrn	A	G	10: 12,585,807 (GRCm39)	F990S	probably benign	Het

Other mutations in V1rd19

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL02898:V1rd19	APN	7	23,702,854 (GRCm39)	missense	probably damaging	1.00
IGL03231:V1rd19	APN	7	23,703,328 (GRCm39)	missense	probably benign	0.00
R0021:V1rd19	UTSW	7	23,703,029 (GRCm39)	missense	probably damaging	0.98
R0184:V1rd19	UTSW	7	23,702,632 (GRCm39)	missense	probably benign	0.06
R0391:V1rd19	UTSW	7	23,703,010 (GRCm39)	missense	probably damaging	0.98
R1520:V1rd19	UTSW	7	23,702,623 (GRCm39)	missense	probably damaging	0.99
R1635:V1rd19	UTSW	7	23,702,812 (GRCm39)	missense	probably benign	0.30
R1861:V1rd19	UTSW	7	23,703,149 (GRCm39)	missense	probably damaging	1.00
R1889:V1rd19	UTSW	7	23,702,632 (GRCm39)	missense	probably benign	0.06
R2008:V1rd19	UTSW	7	23,702,726 (GRCm39)	nonsense	probably null
R2059:V1rd19	UTSW	7	23,703,259 (GRCm39)	missense	probably benign	0.01
R2098:V1rd19	UTSW	7	23,703,160 (GRCm39)	missense	probably damaging	1.00
R3001:V1rd19	UTSW	7	23,703,310 (GRCm39)	missense	probably benign	0.00
R3002:V1rd19	UTSW	7	23,703,310 (GRCm39)	missense	probably benign	0.00
R4271:V1rd19	UTSW	7	23,702,839 (GRCm39)	missense	probably benign	0.36
R5130:V1rd19	UTSW	7	23,702,537 (GRCm39)	start codon destroyed	probably null	1.00
R5169:V1rd19	UTSW	7	23,703,209 (GRCm39)	missense	possibly damaging	0.75
R5297:V1rd19	UTSW	7	23,702,714 (GRCm39)	missense	probably damaging	0.99
R5924:V1rd19	UTSW	7	23,703,374 (GRCm39)	missense	probably benign
R6181:V1rd19	UTSW	7	23,702,640 (GRCm39)	missense	possibly damaging	0.46
R6540:V1rd19	UTSW	7	23,703,056 (GRCm39)	nonsense	probably null
R7331:V1rd19	UTSW	7	23,703,308 (GRCm39)	missense	probably damaging	0.97
R7332:V1rd19	UTSW	7	23,702,743 (GRCm39)	missense	probably benign	0.09
R8338:V1rd19	UTSW	7	23,702,674 (GRCm39)	nonsense	probably null
R8398:V1rd19	UTSW	7	23,703,374 (GRCm39)	nonsense	probably null
R8881:V1rd19	UTSW	7	23,703,081 (GRCm39)	missense	possibly damaging	0.95
R9536:V1rd19	UTSW	7	23,703,253 (GRCm39)	missense	probably damaging	1.00
X0065:V1rd19	UTSW	7	23,702,761 (GRCm39)	missense	probably benign	0.08

Posted On

2015-04-16