Incidental Mutation 'IGL02636:Eci3'
List |< first << previous [record 6 of 33] next >> last >|
ID301523
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Eci3
Ensembl Gene ENSMUSG00000021416
Gene Nameenoyl-Coenzyme A delta isomerase 3
Synonyms
Accession Numbers
Is this an essential gene? Non essential (E-score: 0.000) question?
Stock #IGL02636
Quality Score
Status
Chromosome13
Chromosomal Location34946614-34963810 bp(-) (GRCm38)
Type of Mutationunclassified (1104 bp from exon)
DNA Base Change (assembly) A to T at 34946980 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000132701 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000021853] [ENSMUST00000160279] [ENSMUST00000160905] [ENSMUST00000164155]
Predicted Effect probably null
Transcript: ENSMUST00000021853
AA Change: Y301*
SMART Domains Protein: ENSMUSP00000021853
Gene: ENSMUSG00000021416
AA Change: Y301*

DomainStartEndE-ValueType
Pfam:ACBP 1 42 3.4e-10 PFAM
Pfam:ECH_1 67 314 4.7e-41 PFAM
Pfam:ECH_2 72 316 1e-21 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000160279
SMART Domains Protein: ENSMUSP00000125324
Gene: ENSMUSG00000021415

DomainStartEndE-ValueType
Pfam:DUF4523 34 199 1.1e-89 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000160905
SMART Domains Protein: ENSMUSP00000125206
Gene: ENSMUSG00000021415

DomainStartEndE-ValueType
Pfam:DUF4523 34 199 9.5e-102 PFAM
Predicted Effect probably null
Transcript: ENSMUST00000164155
SMART Domains Protein: ENSMUSP00000132701
Gene: ENSMUSG00000021416

DomainStartEndE-ValueType
Pfam:ACBP 1 45 4.4e-10 PFAM
Pfam:ECH 65 260 5.4e-36 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 32 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Alms1 C A 6: 85,628,654 Q1960K probably benign Het
Arhgef40 T A 14: 51,997,408 V1056E probably damaging Het
Cdh26 T A 2: 178,449,962 F105I probably damaging Het
Cep162 A T 9: 87,248,379 D59E possibly damaging Het
Cngb3 A T 4: 19,396,690 T348S probably damaging Het
Gapvd1 A G 2: 34,725,404 I409T probably benign Het
Golga2 T C 2: 32,296,723 probably null Het
Hoxd3 G A 2: 74,746,954 A393T probably benign Het
Htr5a T C 5: 27,842,660 F71S probably damaging Het
Hyou1 T C 9: 44,381,410 probably null Het
Igsf6 C A 7: 121,067,280 probably benign Het
Klrb1c C A 6: 128,788,552 C25F probably benign Het
Lrguk C A 6: 34,090,188 T483K probably damaging Het
Lrpprc A T 17: 84,753,104 probably benign Het
Lrrk1 A T 7: 66,308,659 probably null Het
Megf8 G A 7: 25,358,432 G2098D probably damaging Het
Nfkbia T C 12: 55,491,173 Q165R possibly damaging Het
Nipsnap2 A G 5: 129,745,290 probably benign Het
Phykpl C T 11: 51,598,713 T382I probably damaging Het
Prdm10 A G 9: 31,329,681 D206G possibly damaging Het
Rab26 T C 17: 24,533,559 S9G probably benign Het
Sema3e C A 5: 14,225,656 N258K probably benign Het
Slfn10-ps T A 11: 83,030,145 noncoding transcript Het
Tgm5 A T 2: 121,076,796 C149S probably damaging Het
Timp4 C T 6: 115,249,824 probably null Het
Traf7 T C 17: 24,512,990 K251E probably benign Het
Ugcg G T 4: 59,207,763 R34L possibly damaging Het
Unc13d T C 11: 116,073,618 H300R probably damaging Het
Vmn1r20 G T 6: 57,431,761 C24F probably benign Het
Vmn2r13 T C 5: 109,192,017 R31G probably damaging Het
Vsig10l A G 7: 43,463,578 T87A possibly damaging Het
Zfp353-ps T A 8: 42,082,440 noncoding transcript Het
Other mutations in Eci3
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01933:Eci3 APN 13 34948789 missense probably damaging 0.99
R0217:Eci3 UTSW 13 34948089 missense probably benign 0.01
R0627:Eci3 UTSW 13 34948143 missense possibly damaging 0.78
R1529:Eci3 UTSW 13 34956920 missense probably benign 0.00
R1840:Eci3 UTSW 13 34960041 missense probably benign 0.38
R1856:Eci3 UTSW 13 34953028 missense possibly damaging 0.56
R4620:Eci3 UTSW 13 34948758 missense probably damaging 1.00
R5186:Eci3 UTSW 13 34946978 missense possibly damaging 0.53
R5427:Eci3 UTSW 13 34959948 missense possibly damaging 0.81
R7400:Eci3 UTSW 13 34959977 missense probably benign
R8083:Eci3 UTSW 13 34956890 missense probably benign 0.00
Posted On2015-04-16