Incidental Mutation 'IGL02636:Vmn1r20'
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ID301525
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Vmn1r20
Ensembl Gene ENSMUSG00000115253
Gene Namevomeronasal 1 receptor 20
SynonymsGm5569
Accession Numbers
Is this an essential gene? Possibly non essential (E-score: 0.487) question?
Stock #IGL02636
Quality Score
Status
Chromosome6
Chromosomal Location57428930-57435261 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) G to T at 57431761 bp
ZygosityHeterozygous
Amino Acid Change Cysteine to Phenylalanine at position 24 (C24F)
Ref Sequence ENSEMBL: ENSMUSP00000153815 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000176085] [ENSMUST00000226808] [ENSMUST00000227909]
Predicted Effect probably benign
Transcript: ENSMUST00000176085
AA Change: C24F

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
SMART Domains Protein: ENSMUSP00000134973
Gene: ENSMUSG00000093679
AA Change: C24F

DomainStartEndE-ValueType
Pfam:V1R 28 293 2.3e-51 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000226808
AA Change: C24F

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
Predicted Effect probably benign
Transcript: ENSMUST00000227909
AA Change: C24F

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 32 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Alms1 C A 6: 85,628,654 Q1960K probably benign Het
Arhgef40 T A 14: 51,997,408 V1056E probably damaging Het
Cdh26 T A 2: 178,449,962 F105I probably damaging Het
Cep162 A T 9: 87,248,379 D59E possibly damaging Het
Cngb3 A T 4: 19,396,690 T348S probably damaging Het
Eci3 A T 13: 34,946,980 probably null Het
Gapvd1 A G 2: 34,725,404 I409T probably benign Het
Golga2 T C 2: 32,296,723 probably null Het
Hoxd3 G A 2: 74,746,954 A393T probably benign Het
Htr5a T C 5: 27,842,660 F71S probably damaging Het
Hyou1 T C 9: 44,381,410 probably null Het
Igsf6 C A 7: 121,067,280 probably benign Het
Klrb1c C A 6: 128,788,552 C25F probably benign Het
Lrguk C A 6: 34,090,188 T483K probably damaging Het
Lrpprc A T 17: 84,753,104 probably benign Het
Lrrk1 A T 7: 66,308,659 probably null Het
Megf8 G A 7: 25,358,432 G2098D probably damaging Het
Nfkbia T C 12: 55,491,173 Q165R possibly damaging Het
Nipsnap2 A G 5: 129,745,290 probably benign Het
Phykpl C T 11: 51,598,713 T382I probably damaging Het
Prdm10 A G 9: 31,329,681 D206G possibly damaging Het
Rab26 T C 17: 24,533,559 S9G probably benign Het
Sema3e C A 5: 14,225,656 N258K probably benign Het
Slfn10-ps T A 11: 83,030,145 noncoding transcript Het
Tgm5 A T 2: 121,076,796 C149S probably damaging Het
Timp4 C T 6: 115,249,824 probably null Het
Traf7 T C 17: 24,512,990 K251E probably benign Het
Ugcg G T 4: 59,207,763 R34L possibly damaging Het
Unc13d T C 11: 116,073,618 H300R probably damaging Het
Vmn2r13 T C 5: 109,192,017 R31G probably damaging Het
Vsig10l A G 7: 43,463,578 T87A possibly damaging Het
Zfp353-ps T A 8: 42,082,440 noncoding transcript Het
Other mutations in Vmn1r20
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01761:Vmn1r20 APN 6 57431740 missense probably damaging 1.00
IGL02622:Vmn1r20 APN 6 57432598 missense probably damaging 0.99
R0006:Vmn1r20 UTSW 6 57432305 missense probably damaging 0.99
R0079:Vmn1r20 UTSW 6 57431792 missense possibly damaging 0.70
R0200:Vmn1r20 UTSW 6 57432099 missense probably damaging 0.96
R1675:Vmn1r20 UTSW 6 57431952 missense probably benign 0.00
R1734:Vmn1r20 UTSW 6 57432300 missense probably damaging 1.00
R1883:Vmn1r20 UTSW 6 57432321 missense probably benign 0.14
R2049:Vmn1r20 UTSW 6 57431958 missense probably damaging 1.00
R2307:Vmn1r20 UTSW 6 57432136 missense probably benign 0.03
R2346:Vmn1r20 UTSW 6 57431946 missense possibly damaging 0.83
R4405:Vmn1r20 UTSW 6 57432057 missense probably benign 0.02
R4946:Vmn1r20 UTSW 6 57432174 missense probably damaging 0.98
R5259:Vmn1r20 UTSW 6 57432065 nonsense probably null
R5321:Vmn1r20 UTSW 6 57432442 missense probably benign 0.21
R5911:Vmn1r20 UTSW 6 57431789 missense probably benign 0.16
R6042:Vmn1r20 UTSW 6 57432406 missense possibly damaging 0.90
R6298:Vmn1r20 UTSW 6 57432127 missense probably benign
R6314:Vmn1r20 UTSW 6 57432057 missense probably benign 0.00
R6331:Vmn1r20 UTSW 6 57431670 unclassified probably null
R6482:Vmn1r20 UTSW 6 57432108 missense probably benign 0.01
Posted On2015-04-16