Incidental Mutation 'IGL02639:Gm2035'
ID301641
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm2035
Ensembl Gene ENSMUSG00000096619
Gene Namepredicted pseudogene 2035
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.232) question?
Stock #IGL02639
Quality Score
Status
Chromosome12
Chromosomal Location87919423-87919857 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) G to T at 87919499 bp
ZygosityHeterozygous
Amino Acid Change Threonine to Lysine at position 120 (T120K)
Ref Sequence ENSEMBL: ENSMUSP00000137146 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000180053]
Predicted Effect probably benign
Transcript: ENSMUST00000180053
AA Change: T120K

PolyPhen 2 Score 0.043 (Sensitivity: 0.94; Specificity: 0.83)
SMART Domains Protein: ENSMUSP00000137146
Gene: ENSMUSG00000096619
AA Change: T120K

DomainStartEndE-ValueType
low complexity region 3 25 N/A INTRINSIC
eIF1a 28 110 4.13e-45 SMART
low complexity region 125 144 N/A INTRINSIC
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 39 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
4930447A16Rik C T 15: 37,429,804 R71* probably null Het
Abca5 A T 11: 110,288,073 I1140N possibly damaging Het
Atp6v0a1 T A 11: 101,055,518 I773N possibly damaging Het
Atp9a A G 2: 168,649,620 M675T probably damaging Het
Baz1a A G 12: 54,896,025 probably benign Het
Cd5l T C 3: 87,368,506 V261A probably damaging Het
Copb1 A G 7: 114,226,595 probably benign Het
Cul5 T C 9: 53,655,342 D130G possibly damaging Het
Cyp2j5 T A 4: 96,658,749 Q176L probably benign Het
D430042O09Rik A G 7: 125,872,792 I1518V probably damaging Het
Ddo A G 10: 40,647,737 D241G probably damaging Het
Defa29 A G 8: 21,326,121 C77R possibly damaging Het
Dpp4 T C 2: 62,352,240 N566D probably benign Het
Emilin2 T C 17: 71,274,549 D394G probably benign Het
Fbf1 T C 11: 116,152,600 E461G probably benign Het
Fgfr2 A G 7: 130,228,802 probably benign Het
Fibcd1 G A 2: 31,817,150 T365M probably damaging Het
Fndc3a A C 14: 72,574,357 H344Q probably benign Het
Fnip1 T A 11: 54,475,640 C52* probably null Het
Fto T A 8: 91,409,528 N143K probably damaging Het
Hells G T 19: 38,938,429 L84F probably damaging Het
Hydin G A 8: 110,538,449 V2755I probably benign Het
Irgq C A 7: 24,531,462 A26E probably damaging Het
Klhl29 A T 12: 5,137,453 Y304N probably damaging Het
Muc6 T C 7: 141,649,578 probably benign Het
Myo15 T C 11: 60,478,621 F736L probably benign Het
Nynrin G T 14: 55,870,655 W1073L probably damaging Het
Olfr116 A T 17: 37,623,987 I216N probably benign Het
Olfr1490 A T 19: 13,654,596 T51S possibly damaging Het
Olfr310 A T 7: 86,269,720 I23N probably damaging Het
Olfr389 A T 11: 73,776,545 C261S probably benign Het
Olfr63 G A 17: 33,269,395 V224M possibly damaging Het
Olfr642 C A 7: 104,049,781 C191F probably damaging Het
Olfr675 T A 7: 105,024,222 I253F probably damaging Het
Pdzd2 T A 15: 12,592,243 K105M probably damaging Het
Pip5k1c C A 10: 81,317,321 probably null Het
Pola2 A G 19: 5,953,774 V191A probably benign Het
Slc22a8 A T 19: 8,593,959 Y18F probably benign Het
Slc26a5 C T 5: 21,819,767 V440M probably damaging Het
Other mutations in Gm2035
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02314:Gm2035 APN 12 87919607 missense probably benign 0.00
IGL02347:Gm2035 APN 12 87919589 missense probably damaging 1.00
R4230:Gm2035 UTSW 12 87919797 missense unknown
R5969:Gm2035 UTSW 12 87919478 missense unknown
R6159:Gm2035 UTSW 12 87919751 missense probably damaging 1.00
R6359:Gm2035 UTSW 12 87919505 missense probably benign 0.09
R7181:Gm2035 UTSW 12 87919722 missense possibly damaging 0.49
R7183:Gm2035 UTSW 12 87919722 missense possibly damaging 0.49
R7184:Gm2035 UTSW 12 87919722 missense possibly damaging 0.49
R7653:Gm2035 UTSW 12 87919478 missense unknown
R8046:Gm2035 UTSW 12 87919565 missense probably benign 0.02
R8353:Gm2035 UTSW 12 87919553 missense probably benign
R8453:Gm2035 UTSW 12 87919553 missense probably benign
Posted On2015-04-16