Incidental Mutation 'IGL02641:Vmn1r202'
| ID |
301722 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Vmn1r202
|
| Ensembl Gene |
ENSMUSG00000094379 |
| Gene Name |
vomeronasal 1 receptor 202 |
| Synonyms |
V1ri7 |
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.088)
|
| Stock # |
IGL02641
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
13 |
| Chromosomal Location |
22685507-22686415 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to G
at 22686274 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Leucine
at position 48
(I48L)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000154314
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000078642]
[ENSMUST00000228020]
|
| AlphaFold |
Q8R259 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000078642
AA Change: I48L
PolyPhen 2
Score 0.336 (Sensitivity: 0.90; Specificity: 0.89)
|
| SMART Domains |
Protein: ENSMUSP00000077711
Gene: ENSMUSG00000094379
AA Change: I48L
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:TAS2R
|
5 |
301 |
2.2e-11 |
PFAM |
|
Pfam:V1R
|
35 |
300 |
5.6e-44 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000228020
AA Change: I48L
PolyPhen 2
Score 0.336 (Sensitivity: 0.90; Specificity: 0.89)
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 30 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 3100002H09Rik |
A |
T |
4: 124,504,510 (GRCm39) |
M14K |
unknown |
Het |
| Arhgap24 |
T |
C |
5: 103,040,386 (GRCm39) |
V441A |
probably damaging |
Het |
| Cdv3 |
G |
T |
9: 103,241,223 (GRCm39) |
Q115K |
probably damaging |
Het |
| Clstn1 |
G |
T |
4: 149,713,968 (GRCm39) |
G207C |
probably null |
Het |
| Col28a1 |
A |
T |
6: 8,014,794 (GRCm39) |
Y870* |
probably null |
Het |
| Creb3 |
A |
C |
4: 43,563,311 (GRCm39) |
H136P |
probably benign |
Het |
| Dcaf17 |
G |
A |
2: 70,912,375 (GRCm39) |
C320Y |
probably damaging |
Het |
| Fbl |
T |
C |
7: 27,874,471 (GRCm39) |
S66P |
probably damaging |
Het |
| Fgfrl1 |
C |
A |
5: 108,853,731 (GRCm39) |
S279R |
probably damaging |
Het |
| Gdpgp1 |
C |
T |
7: 79,888,796 (GRCm39) |
R276* |
probably null |
Het |
| Hcfc2 |
A |
G |
10: 82,538,383 (GRCm39) |
Y140C |
probably damaging |
Het |
| Ighg3 |
A |
G |
12: 113,323,818 (GRCm39) |
I190T |
unknown |
Het |
| Itgav |
T |
C |
2: 83,598,689 (GRCm39) |
|
probably benign |
Het |
| Lce1c |
C |
A |
3: 92,587,845 (GRCm39) |
|
probably benign |
Het |
| Ldoc1 |
G |
A |
X: 60,753,419 (GRCm39) |
C35Y |
probably damaging |
Het |
| Lrp10 |
T |
A |
14: 54,706,068 (GRCm39) |
C419* |
probably null |
Het |
| Micall2 |
T |
C |
5: 139,705,094 (GRCm39) |
D80G |
probably damaging |
Het |
| Or5b21 |
T |
A |
19: 12,839,566 (GRCm39) |
C142* |
probably null |
Het |
| Pde3b |
C |
T |
7: 114,130,052 (GRCm39) |
T869I |
probably damaging |
Het |
| Pip5k1c |
C |
A |
10: 81,153,155 (GRCm39) |
|
probably null |
Het |
| Pkhd1 |
G |
A |
1: 20,628,976 (GRCm39) |
T657I |
possibly damaging |
Het |
| Pnisr |
A |
G |
4: 21,860,908 (GRCm39) |
N197S |
probably benign |
Het |
| Rpl21-ps4 |
G |
A |
14: 11,227,661 (GRCm38) |
|
noncoding transcript |
Het |
| Rtn4rl1 |
A |
C |
11: 75,156,650 (GRCm39) |
T361P |
probably damaging |
Het |
| Spaca9 |
C |
A |
2: 28,585,963 (GRCm39) |
E34* |
probably null |
Het |
| Trip10 |
T |
A |
17: 57,569,411 (GRCm39) |
D478E |
probably benign |
Het |
| Tsc22d2 |
A |
G |
3: 58,323,576 (GRCm39) |
D156G |
probably damaging |
Het |
| Ufc1 |
T |
C |
1: 171,117,764 (GRCm39) |
D50G |
probably damaging |
Het |
| Vmn2r111 |
A |
T |
17: 22,792,205 (GRCm39) |
V17E |
possibly damaging |
Het |
| Vps13a |
T |
A |
19: 16,676,185 (GRCm39) |
M1263L |
probably benign |
Het |
|
| Other mutations in Vmn1r202 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01472:Vmn1r202
|
APN |
13 |
22,686,159 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL01516:Vmn1r202
|
APN |
13 |
22,685,632 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
IGL01722:Vmn1r202
|
APN |
13 |
22,685,890 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02863:Vmn1r202
|
APN |
13 |
22,685,640 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02876:Vmn1r202
|
APN |
13 |
22,685,640 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02891:Vmn1r202
|
APN |
13 |
22,685,640 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02943:Vmn1r202
|
APN |
13 |
22,686,364 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL03057:Vmn1r202
|
APN |
13 |
22,685,640 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03114:Vmn1r202
|
APN |
13 |
22,685,500 (GRCm39) |
utr 3 prime |
probably benign |
|
|
IGL03114:Vmn1r202
|
APN |
13 |
22,685,640 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03143:Vmn1r202
|
APN |
13 |
22,685,640 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03159:Vmn1r202
|
APN |
13 |
22,685,640 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03097:Vmn1r202
|
UTSW |
13 |
22,685,640 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0611:Vmn1r202
|
UTSW |
13 |
22,685,824 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1350:Vmn1r202
|
UTSW |
13 |
22,685,886 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1666:Vmn1r202
|
UTSW |
13 |
22,685,540 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1668:Vmn1r202
|
UTSW |
13 |
22,685,540 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1803:Vmn1r202
|
UTSW |
13 |
22,686,313 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2035:Vmn1r202
|
UTSW |
13 |
22,685,772 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2112:Vmn1r202
|
UTSW |
13 |
22,685,904 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R2145:Vmn1r202
|
UTSW |
13 |
22,685,953 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R3026:Vmn1r202
|
UTSW |
13 |
22,685,932 (GRCm39) |
missense |
probably benign |
0.03 |
|
R3808:Vmn1r202
|
UTSW |
13 |
22,686,070 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R4714:Vmn1r202
|
UTSW |
13 |
22,685,977 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5016:Vmn1r202
|
UTSW |
13 |
22,686,375 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5124:Vmn1r202
|
UTSW |
13 |
22,685,920 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6136:Vmn1r202
|
UTSW |
13 |
22,685,632 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R6365:Vmn1r202
|
UTSW |
13 |
22,686,374 (GRCm39) |
missense |
probably benign |
0.12 |
|
R6982:Vmn1r202
|
UTSW |
13 |
22,685,917 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7293:Vmn1r202
|
UTSW |
13 |
22,685,872 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7502:Vmn1r202
|
UTSW |
13 |
22,686,188 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7603:Vmn1r202
|
UTSW |
13 |
22,685,790 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7672:Vmn1r202
|
UTSW |
13 |
22,685,850 (GRCm39) |
missense |
probably benign |
0.45 |
|
R7822:Vmn1r202
|
UTSW |
13 |
22,686,241 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7954:Vmn1r202
|
UTSW |
13 |
22,685,871 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8026:Vmn1r202
|
UTSW |
13 |
22,686,314 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R8419:Vmn1r202
|
UTSW |
13 |
22,685,985 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9079:Vmn1r202
|
UTSW |
13 |
22,685,602 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9194:Vmn1r202
|
UTSW |
13 |
22,686,316 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
| Posted On |
2015-04-16 |
Incidental Mutation