Incidental Mutation 'IGL02654:Anxa13'
ID302289
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Anxa13
Ensembl Gene ENSMUSG00000055114
Gene Nameannexin A13
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.125) question?
Stock #IGL02654
Quality Score
Status
Chromosome15
Chromosomal Location58341874-58364148 bp(-) (GRCm38)
Type of Mutationsplice site
DNA Base Change (assembly) A to G at 58342001 bp
ZygosityHeterozygous
Amino Acid Change
Gene Model predicted gene model for transcript(s): [ENSMUST00000068515]
Predicted Effect noncoding transcript
Transcript: ENSMUST00000068515
SMART Domains Protein: ENSMUSP00000065295
Gene: ENSMUSG00000055114

DomainStartEndE-ValueType
ANX 27 79 1.07e-23 SMART
ANX 99 151 8.37e-26 SMART
low complexity region 192 203 N/A INTRINSIC
ANX 250 302 1.65e-24 SMART
Predicted Effect noncoding transcript
Transcript: ENSMUST00000227274
Coding Region Coverage
Validation Efficiency
MGI Phenotype FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. The specific function of this gene has not yet been determined; however, it is associated with the plasma membrane of undifferentiated, proliferating endothelial cells and differentiated villus enterocytes. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Allele List at MGI
Other mutations in this stock
Total: 34 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Abcb4 T C 5: 8,927,826 I468T possibly damaging Het
Arhgef33 A G 17: 80,370,311 Y429C probably damaging Het
BC024978 A G 7: 27,203,873 E289G probably damaging Het
Bdh1 T C 16: 31,456,615 probably benign Het
C77080 C T 4: 129,222,319 G851R probably damaging Het
Dennd4a A G 9: 64,910,191 probably benign Het
Dld G T 12: 31,333,917 H396N probably benign Het
Dsg1b T C 18: 20,409,262 V942A probably damaging Het
Eln A T 5: 134,717,054 probably benign Het
Fat3 G A 9: 15,996,975 T2577M possibly damaging Het
Gad1 A T 2: 70,572,781 K73M possibly damaging Het
Gipc1 T C 8: 83,663,151 V253A probably damaging Het
Gm21671 T A 5: 25,953,207 H49L probably benign Het
Gtpbp10 A C 5: 5,543,372 probably benign Het
Hgf A T 5: 16,561,051 T62S probably benign Het
Hivep1 T C 13: 42,157,685 S1134P probably damaging Het
Hnrnpc A G 14: 52,084,117 L80S probably damaging Het
Kif20a G A 18: 34,632,023 R770H probably damaging Het
Lcat T C 8: 105,939,769 T374A possibly damaging Het
Mlana A G 19: 29,704,618 probably null Het
Nynrin A G 14: 55,863,259 I169V possibly damaging Het
Olfr697 A T 7: 106,741,348 Y195* probably null Het
P3h3 A G 6: 124,845,265 V585A possibly damaging Het
Pcdhb17 T A 18: 37,486,561 M468K probably benign Het
Prl8a2 T G 13: 27,352,797 I134S possibly damaging Het
Rev3l T C 10: 39,862,734 V2828A probably damaging Het
Rhbdd1 G T 1: 82,342,783 V163F probably benign Het
Rrp1 A G 10: 78,412,939 V5A probably benign Het
Sephs1 A T 2: 4,884,555 N48I probably benign Het
Vmn1r71 A G 7: 10,748,315 Y149H probably benign Het
Wiz T C 17: 32,359,350 D396G probably damaging Het
Xirp2 A G 2: 67,514,671 S2419G possibly damaging Het
Zfp128 A G 7: 12,884,679 T35A possibly damaging Het
Zmym2 T A 14: 56,911,315 F362Y probably damaging Het
Other mutations in Anxa13
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01417:Anxa13 APN 15 58356194 exon noncoding transcript
IGL02192:Anxa13 APN 15 58348780 exon noncoding transcript
R1572:Anxa13 UTSW 15 58348807 splice site noncoding transcript
R1973:Anxa13 UTSW 15 58356181 exon noncoding transcript
R1988:Anxa13 UTSW 15 58341948 exon noncoding transcript
R1989:Anxa13 UTSW 15 58341948 exon noncoding transcript
R2916:Anxa13 UTSW 15 58345080 intron noncoding transcript
R4504:Anxa13 UTSW 15 58356203 exon noncoding transcript
R5832:Anxa13 UTSW 15 58341993 splice site noncoding transcript
R6526:Anxa13 UTSW 15 58344957 exon noncoding transcript
Posted On2015-04-16