Incidental Mutation 'IGL02662:Gm11397'
ID302582
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm11397
Ensembl Gene ENSMUSG00000071452
Gene Namepredicted gene 11397
Synonyms
Accession Numbers
Is this an essential gene? Possibly non essential (E-score: 0.298) question?
Stock #IGL02662
Quality Score
Status
Chromosome13
Chromosomal Location33395761-33405285 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to G at 33404530 bp
ZygosityHeterozygous
Amino Acid Change Asparagine to Serine at position 366 (N366S)
Ref Sequence ENSEMBL: ENSMUSP00000049819 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000050276]
Predicted Effect possibly damaging
Transcript: ENSMUST00000050276
AA Change: N366S

PolyPhen 2 Score 0.513 (Sensitivity: 0.88; Specificity: 0.90)
SMART Domains Protein: ENSMUSP00000049819
Gene: ENSMUSG00000071452
AA Change: N366S

DomainStartEndE-ValueType
SERPIN 13 377 1.3e-164 SMART
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 38 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Adcy8 A G 15: 64,746,895 probably null Het
Ap5z1 G A 5: 142,476,889 probably null Het
Cdhr5 T G 7: 141,274,503 I120L possibly damaging Het
Chd5 C T 4: 152,372,131 S975F probably damaging Het
Cts3 G T 13: 61,568,057 Q132K probably damaging Het
Cylc2 T A 4: 51,216,698 probably benign Het
Defb39 A G 8: 19,052,875 V68A probably benign Het
Dgki A G 6: 36,862,486 probably benign Het
Dhtkd1 G A 2: 5,899,972 P867L probably damaging Het
Gata5 C T 2: 180,327,751 probably benign Het
Glt28d2 T A 3: 85,872,116 I17F probably damaging Het
Gstm2 T C 3: 107,985,062 Y82C possibly damaging Het
Hs6st1 T A 1: 36,103,812 L276* probably null Het
Iqgap1 T C 7: 80,743,079 D712G probably benign Het
Kdm4c T C 4: 74,404,821 S997P probably damaging Het
Ksr1 G A 11: 79,036,725 T289I probably damaging Het
Lingo4 T C 3: 94,401,817 probably benign Het
Ncapd2 A G 6: 125,176,731 S674P probably damaging Het
Nek1 G A 8: 61,104,184 V841I probably benign Het
Olfr1104 T C 2: 87,022,002 T181A probably benign Het
Olfr514 T C 7: 108,825,745 T85A probably benign Het
Pigx A G 16: 32,087,383 V40A probably damaging Het
Pla2g2d T G 4: 138,778,695 M5R possibly damaging Het
Ppa2 G T 3: 133,367,883 R234I probably damaging Het
Rbms1 A C 2: 60,762,306 L221R probably damaging Het
Rnasel C A 1: 153,754,111 N124K probably damaging Het
Sigirr T A 7: 141,094,794 probably benign Het
Tas2r136 A T 6: 132,777,708 V152E probably damaging Het
Tlnrd1 C T 7: 83,882,819 V135M possibly damaging Het
Tlnrd1 A G 7: 83,882,536 L229S probably damaging Het
Top1mt A G 15: 75,668,705 V239A probably damaging Het
Tpd52 A T 3: 8,944,715 probably null Het
Trim16 T A 11: 62,840,557 L331Q possibly damaging Het
Ttll4 A G 1: 74,687,231 probably null Het
Vmn1r27 T A 6: 58,215,287 D244V probably damaging Het
Vmn2r72 A C 7: 85,738,183 D724E probably benign Het
Zfp563 T C 17: 33,102,279 W18R probably damaging Het
Zswim8 T C 14: 20,713,074 V347A probably benign Het
Other mutations in Gm11397
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02206:Gm11397 APN 13 33404199 missense probably damaging 0.99
R0017:Gm11397 UTSW 13 33404511 missense probably damaging 0.99
R1343:Gm11397 UTSW 13 33404485 missense possibly damaging 0.47
R1757:Gm11397 UTSW 13 33399353 missense probably benign 0.00
R1886:Gm11397 UTSW 13 33404220 missense possibly damaging 0.56
R5559:Gm11397 UTSW 13 33404318 missense probably benign
R5681:Gm11397 UTSW 13 33395829 missense probably damaging 0.98
R6189:Gm11397 UTSW 13 33404444 missense probably benign
R7585:Gm11397 UTSW 13 33404316 missense probably benign 0.43
R7746:Gm11397 UTSW 13 33397858 missense probably damaging 0.98
Posted On2015-04-16