Incidental Mutation 'IGL02664:Ppp1r32'
ID302682
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Ppp1r32
Ensembl Gene ENSMUSG00000035179
Gene Nameprotein phosphatase 1, regulatory subunit 32
SynonymsIIIG9L, 4930579J09Rik, IIIG9S, IIIG9
Accession Numbers
Is this an essential gene? Non essential (E-score: 0.000) question?
Stock #IGL02664
Quality Score
Status
Chromosome19
Chromosomal Location10474257-10482897 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to T at 10482291 bp
ZygosityHeterozygous
Amino Acid Change Serine to Arginine at position 17 (S17R)
Ref Sequence ENSEMBL: ENSMUSP00000035684 (fasta)
Predicted Effect probably damaging
Transcript: ENSMUST00000038842
AA Change: S17R

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 46 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Ablim2 A T 5: 35,849,516 D425V probably damaging Het
Afdn G T 17: 13,852,466 probably benign Het
Ap2a2 C T 7: 141,629,223 T776I probably benign Het
Apcdd1 T C 18: 62,951,820 probably benign Het
Bdp1 A T 13: 100,051,539 Y1513N probably benign Het
Btaf1 T C 19: 36,978,428 probably benign Het
C2cd3 A T 7: 100,419,715 M917L possibly damaging Het
Cmtm6 T C 9: 114,746,545 V174A probably benign Het
Cyp2d12 T A 15: 82,559,334 I448K probably benign Het
Ddb1 A G 19: 10,607,883 I101V probably benign Het
Dicer1 A G 12: 104,705,129 Y961H probably damaging Het
Dnaaf1 T G 8: 119,582,521 I116S probably damaging Het
Ecscr T A 18: 35,721,398 I5F possibly damaging Het
Eftud2 T C 11: 102,841,712 E691G probably damaging Het
Fat2 A G 11: 55,311,096 V384A probably damaging Het
Ftcd T C 10: 76,584,605 M391T probably damaging Het
Gab2 T G 7: 97,304,182 S587R probably damaging Het
Gm18856 G A 13: 13,965,224 probably benign Het
Herc2 A T 7: 56,135,678 R1559* probably null Het
Inpp5f G A 7: 128,664,014 R161H probably damaging Het
Iws1 A T 18: 32,070,164 D31V possibly damaging Het
Klhl2 A T 8: 64,752,767 Y373* probably null Het
Lce6a A T 3: 92,620,300 C67S possibly damaging Het
Lrba A G 3: 86,325,731 I800V possibly damaging Het
Mis18bp1 A C 12: 65,153,880 Y407* probably null Het
Mllt3 A C 4: 88,031,623 W29G probably damaging Het
Mon2 A G 10: 123,009,496 probably benign Het
Mtbp C T 15: 55,619,643 T372M probably benign Het
Nefm A T 14: 68,120,215 probably benign Het
Nf1 A T 11: 79,444,598 probably null Het
Nf1 G A 11: 79,444,599 probably null Het
Ntn1 T A 11: 68,385,469 I218F probably benign Het
Numa1 T G 7: 101,998,902 S613R possibly damaging Het
Olfr305 C T 7: 86,363,603 V245I possibly damaging Het
Pcsk5 A T 19: 17,456,770 D1411E probably damaging Het
Prl2b1 G T 13: 27,385,242 N124K possibly damaging Het
Rab15 T C 12: 76,804,451 I30M possibly damaging Het
Rnf215 G T 11: 4,140,307 V342L probably damaging Het
Spata5 A G 3: 37,436,665 D453G probably damaging Het
Togaram2 T A 17: 71,729,239 I908N probably damaging Het
Trim54 A G 5: 31,136,047 N205S probably damaging Het
Ttn G A 2: 76,867,451 T80I possibly damaging Het
Vmn2r106 G A 17: 20,268,082 T685I possibly damaging Het
Vwa5b2 T C 16: 20,595,313 probably benign Het
Zfat A T 15: 68,180,721 I401N probably damaging Het
Zfp40 G A 17: 23,176,986 S209F probably benign Het
Other mutations in Ppp1r32
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00959:Ppp1r32 APN 19 10477523 critical splice donor site probably null
IGL00979:Ppp1r32 APN 19 10474499 makesense probably null
IGL02405:Ppp1r32 APN 19 10474566 missense probably damaging 1.00
IGL03105:Ppp1r32 APN 19 10477020 splice site probably benign
R0255:Ppp1r32 UTSW 19 10475054 missense probably damaging 1.00
R0268:Ppp1r32 UTSW 19 10477085 missense possibly damaging 0.88
R1018:Ppp1r32 UTSW 19 10479460 splice site probably benign
R1559:Ppp1r32 UTSW 19 10481406 missense probably benign 0.01
R2384:Ppp1r32 UTSW 19 10481282 critical splice donor site probably null
R4362:Ppp1r32 UTSW 19 10475021 missense probably damaging 1.00
R4884:Ppp1r32 UTSW 19 10474501 makesense probably null
R5998:Ppp1r32 UTSW 19 10481352 missense possibly damaging 0.50
R6130:Ppp1r32 UTSW 19 10477764 missense probably benign 0.16
R6360:Ppp1r32 UTSW 19 10479481 missense probably damaging 1.00
R6388:Ppp1r32 UTSW 19 10482301 missense probably damaging 1.00
R6625:Ppp1r32 UTSW 19 10481736 missense probably damaging 0.97
R6754:Ppp1r32 UTSW 19 10477089 missense probably damaging 1.00
R7188:Ppp1r32 UTSW 19 10482338 missense probably benign 0.15
R7361:Ppp1r32 UTSW 19 10479579 missense probably damaging 1.00
R7679:Ppp1r32 UTSW 19 10482254 missense probably damaging 1.00
R8157:Ppp1r32 UTSW 19 10478265 missense probably damaging 1.00
Posted On2015-04-16