Incidental Mutation 'IGL02665:Gm5916'
ID302690
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm5916
Ensembl Gene ENSMUSG00000091411
Gene Namepredicted gene 5916
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.121) question?
Stock #IGL02665
Quality Score
Status
Chromosome9
Chromosomal Location36119934-36128779 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to T at 36128666 bp
ZygosityHeterozygous
Amino Acid Change Phenylalanine to Isoleucine at position 9 (F9I)
Ref Sequence ENSEMBL: ENSMUSP00000125855 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000168452]
Predicted Effect possibly damaging
Transcript: ENSMUST00000168452
AA Change: F9I

PolyPhen 2 Score 0.663 (Sensitivity: 0.86; Specificity: 0.91)
SMART Domains Protein: ENSMUSP00000125855
Gene: ENSMUSG00000091411
AA Change: F9I

DomainStartEndE-ValueType
signal peptide 1 17 N/A INTRINSIC
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 23 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Cenpc1 T C 5: 86,046,403 N168S probably benign Het
Cep295 A G 9: 15,326,632 probably benign Het
Defb20 A G 2: 152,479,576 Y91C probably damaging Het
Dio2 T C 12: 90,729,653 D187G possibly damaging Het
Fat4 G A 3: 39,002,836 R4227Q probably benign Het
Fsip2 G A 2: 82,993,063 G6380D probably damaging Het
Havcr2 T A 11: 46,479,394 V216E probably benign Het
Hdac7 G A 15: 97,796,957 probably benign Het
Itgb8 T C 12: 119,166,865 probably benign Het
Kyat3 A G 3: 142,734,466 probably null Het
Lcn3 G A 2: 25,766,404 A99T possibly damaging Het
Lox T A 18: 52,525,244 probably benign Het
Lrrc7 A G 3: 158,161,105 S1000P probably damaging Het
Muc5ac T C 7: 141,791,086 F98S possibly damaging Het
Nsd1 T C 13: 55,296,183 Y1835H probably damaging Het
Pnpla3 A G 15: 84,171,205 D104G probably benign Het
Rab3ip T A 10: 116,937,548 Q120L probably benign Het
Ranbp6 T A 19: 29,812,901 Q17L possibly damaging Het
Serpinb9g T C 13: 33,495,103 C319R possibly damaging Het
Ska3 T C 14: 57,822,072 K99E probably damaging Het
Srcap T A 7: 127,540,903 S1330R probably damaging Het
Vmn2r82 T A 10: 79,379,371 M396K probably damaging Het
Vmn2r87 T G 10: 130,497,180 D67A probably benign Het
Other mutations in Gm5916
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01145:Gm5916 APN 9 36120702 missense unknown
IGL02103:Gm5916 APN 9 36128674 missense probably damaging 0.97
R5071:Gm5916 UTSW 9 36128668 missense probably benign 0.00
R5347:Gm5916 UTSW 9 36120716 missense probably benign 0.03
R6996:Gm5916 UTSW 9 36128639 missense probably benign 0.14
R7213:Gm5916 UTSW 9 36128650 missense possibly damaging 0.95
R7256:Gm5916 UTSW 9 36120989 missense possibly damaging 0.78
R7890:Gm5916 UTSW 9 36120995 missense possibly damaging 0.92
Posted On2015-04-16