Incidental Mutation 'IGL02665:Gm5916'
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm5916
Ensembl Gene ENSMUSG00000091411
Gene Namepredicted gene 5916
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.121) question?
Stock #IGL02665
Quality Score
Chromosomal Location36119934-36128779 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to T at 36128666 bp
Amino Acid Change Phenylalanine to Isoleucine at position 9 (F9I)
Ref Sequence ENSEMBL: ENSMUSP00000125855 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000168452]
Predicted Effect possibly damaging
Transcript: ENSMUST00000168452
AA Change: F9I

PolyPhen 2 Score 0.663 (Sensitivity: 0.86; Specificity: 0.91)
SMART Domains Protein: ENSMUSP00000125855
Gene: ENSMUSG00000091411
AA Change: F9I

signal peptide 1 17 N/A INTRINSIC
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 23 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Cenpc1 T C 5: 86,046,403 N168S probably benign Het
Cep295 A G 9: 15,326,632 probably benign Het
Defb20 A G 2: 152,479,576 Y91C probably damaging Het
Dio2 T C 12: 90,729,653 D187G possibly damaging Het
Fat4 G A 3: 39,002,836 R4227Q probably benign Het
Fsip2 G A 2: 82,993,063 G6380D probably damaging Het
Havcr2 T A 11: 46,479,394 V216E probably benign Het
Hdac7 G A 15: 97,796,957 probably benign Het
Itgb8 T C 12: 119,166,865 probably benign Het
Kyat3 A G 3: 142,734,466 probably null Het
Lcn3 G A 2: 25,766,404 A99T possibly damaging Het
Lox T A 18: 52,525,244 probably benign Het
Lrrc7 A G 3: 158,161,105 S1000P probably damaging Het
Muc5ac T C 7: 141,791,086 F98S possibly damaging Het
Nsd1 T C 13: 55,296,183 Y1835H probably damaging Het
Pnpla3 A G 15: 84,171,205 D104G probably benign Het
Rab3ip T A 10: 116,937,548 Q120L probably benign Het
Ranbp6 T A 19: 29,812,901 Q17L possibly damaging Het
Serpinb9g T C 13: 33,495,103 C319R possibly damaging Het
Ska3 T C 14: 57,822,072 K99E probably damaging Het
Srcap T A 7: 127,540,903 S1330R probably damaging Het
Vmn2r82 T A 10: 79,379,371 M396K probably damaging Het
Vmn2r87 T G 10: 130,497,180 D67A probably benign Het
Other mutations in Gm5916
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01145:Gm5916 APN 9 36120702 missense unknown
IGL02103:Gm5916 APN 9 36128674 missense probably damaging 0.97
R5071:Gm5916 UTSW 9 36128668 missense probably benign 0.00
R5347:Gm5916 UTSW 9 36120716 missense probably benign 0.03
R6996:Gm5916 UTSW 9 36128639 missense probably benign 0.14
R7213:Gm5916 UTSW 9 36128650 missense possibly damaging 0.95
R7256:Gm5916 UTSW 9 36120989 missense possibly damaging 0.78
R7890:Gm5916 UTSW 9 36120995 missense possibly damaging 0.92
Posted On2015-04-16