Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02676:Vmn1r19'

303115

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn1r19

Ensembl Gene

ENSMUSG00000115799

Gene Name

vomeronasal 1 receptor 19

Synonyms

V1rc27

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.100) question?

Stock #

IGL02676

Quality Score

Status

Chromosome

Chromosomal Location

57403780-57406034 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 57405040 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Isoleucine to Phenylalanine at position 193 (I193F)

Ref Sequence

ENSEMBL: ENSMUSP00000087264 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000089830]

AlphaFold

Q8R2C7

Predicted Effect

possibly damaging
Transcript: ENSMUST00000089830
AA Change: I193F

PolyPhen 2 Score 0.936 (Sensitivity: 0.80; Specificity: 0.94)

SMART Domains

Protein: ENSMUSP00000087264
Gene: ENSMUSG00000115799
AA Change: I193F

Domain	Start	End	E-Value	Type
Pfam:V1R	28	293	6.6e-58	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 48 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Apc	G	A	18: 34,315,634	S1827N	probably damaging	Het
Atrnl1	T	A	19: 57,691,884	C739S	probably damaging	Het
Cep350	T	C	1: 155,862,231	E2622G	possibly damaging	Het
Chd5	C	T	4: 152,356,073		probably benign	Het
Chst11	T	A	10: 83,191,729	L330Q	probably damaging	Het
Clcnka	A	T	4: 141,392,783	V275E	probably damaging	Het
Clip4	G	A	17: 71,828,621	S456N	probably damaging	Het
Cmya5	A	T	13: 93,092,853	I1909N	probably damaging	Het
Cyp26b1	A	G	6: 84,576,644	I176T	probably damaging	Het
Dst	A	G	1: 34,307,587	R7717G	probably damaging	Het
Eml2	C	T	7: 19,184,921	R99*	probably null	Het
Fibin	T	C	2: 110,362,584	Q71R	probably benign	Het
Fsip2	T	G	2: 82,982,157	I2940S	possibly damaging	Het
Gabrb3	G	T	7: 57,591,364		probably benign	Het
Gfra1	G	A	19: 58,453,355	T48I	probably damaging	Het
Gm13083	T	C	4: 143,616,097	F258S	possibly damaging	Het
Gm6205	A	G	5: 94,683,871	T246A	possibly damaging	Het
Gm6483	C	T	8: 19,693,659		noncoding transcript	Het
Hdgfl1	G	A	13: 26,769,365	R242C	possibly damaging	Het
Hmcn1	T	C	1: 150,619,009	T4110A	probably benign	Het
Lama2	T	G	10: 27,118,493	M1807L	probably benign	Het
Larp4	T	C	15: 99,990,421	V113A	possibly damaging	Het
Mkx	T	C	18: 7,000,640	T101A	probably benign	Het
Nfe2l1	A	G	11: 96,827,665	F15L	probably damaging	Het
Nif3l1	G	A	1: 58,455,736		probably null	Het
Nop14	A	G	5: 34,639,221	V764A	probably damaging	Het
Nosip	C	A	7: 45,077,328	A259E	probably damaging	Het
Ntn5	T	C	7: 45,691,876		probably benign	Het
Olfr1016	T	C	2: 85,799,590	I227V	possibly damaging	Het
Phospho1	G	A	11: 95,830,888	G128D	probably damaging	Het
Ppp4r3a	G	A	12: 101,042,511	T703M	probably benign	Het
Prdm8	G	A	5: 98,186,559	E662K	probably damaging	Het
Ralgapa1	A	G	12: 55,676,417	S1775P	probably damaging	Het
Rapgef6	T	C	11: 54,649,346		probably benign	Het
Rasef	T	C	4: 73,759,729	T87A	possibly damaging	Het
Scrn3	A	G	2: 73,329,871	Q286R	probably benign	Het
Sema3d	A	T	5: 12,570,978	Q517L	probably benign	Het
Slc9a3r2	A	T	17: 24,641,956	V204E	probably damaging	Het
Taf6l	T	C	19: 8,775,049	Y425C	probably damaging	Het
Tbk1	T	C	10: 121,568,080	N254S	possibly damaging	Het
Tcf3	C	T	10: 80,421,091	G64R	probably damaging	Het
Tmco4	T	C	4: 139,023,069		probably null	Het
Trappc11	A	G	8: 47,493,413		probably benign	Het
Vmn2r14	G	A	5: 109,220,016	T370I	probably benign	Het
Vmn2r65	T	A	7: 84,940,173	H845L	possibly damaging	Het
Vmn2r98	A	T	17: 19,065,259	T114S	probably benign	Het
Zfp280d	A	T	9: 72,335,074	R661S	probably damaging	Het
Zranb1	T	C	7: 132,966,681	I356T	probably benign	Het

Other mutations in Vmn1r19

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00948:Vmn1r19	APN	6	57405262	missense	probably benign	0.03
IGL01287:Vmn1r19	APN	6	57405194	missense	probably damaging	1.00
IGL01516:Vmn1r19	APN	6	57404872	missense	probably benign	0.03
IGL01895:Vmn1r19	APN	6	57405260	missense	probably benign	0.02
IGL03040:Vmn1r19	APN	6	57405362	missense	unknown
IGL03087:Vmn1r19	APN	6	57404491	missense	probably benign	0.01
PIT4802001:Vmn1r19	UTSW	6	57405052	missense	probably damaging	1.00
R0319:Vmn1r19	UTSW	6	57404615	missense	possibly damaging	0.93
R1368:Vmn1r19	UTSW	6	57404671	missense	probably benign	0.01
R1997:Vmn1r19	UTSW	6	57405048	missense	probably damaging	1.00
R2920:Vmn1r19	UTSW	6	57404924	missense	probably benign	0.03
R3857:Vmn1r19	UTSW	6	57405113	missense	possibly damaging	0.68
R4090:Vmn1r19	UTSW	6	57404735	missense	probably damaging	1.00
R4547:Vmn1r19	UTSW	6	57404789	missense	possibly damaging	0.56
R4823:Vmn1r19	UTSW	6	57405234	nonsense	probably null
R4951:Vmn1r19	UTSW	6	57404942	missense	probably benign	0.36
R5077:Vmn1r19	UTSW	6	57405041	missense	probably benign	0.00
R5459:Vmn1r19	UTSW	6	57404490	nonsense	probably null
R5625:Vmn1r19	UTSW	6	57405296	missense	probably damaging	1.00
R5690:Vmn1r19	UTSW	6	57404795	missense	probably benign	0.10
R5761:Vmn1r19	UTSW	6	57405353	missense	unknown
R6124:Vmn1r19	UTSW	6	57404617	missense	probably benign	0.02
R6373:Vmn1r19	UTSW	6	57405332	missense	unknown
R6476:Vmn1r19	UTSW	6	57404593	missense	probably damaging	0.99
R6938:Vmn1r19	UTSW	6	57405007	missense	possibly damaging	0.94
R7027:Vmn1r19	UTSW	6	57404490	nonsense	probably null
R7359:Vmn1r19	UTSW	6	57405095	missense	probably damaging	0.99
R7568:Vmn1r19	UTSW	6	57404828	missense	possibly damaging	0.69
R7893:Vmn1r19	UTSW	6	57404679	missense	probably damaging	1.00
R8481:Vmn1r19	UTSW	6	57404947	missense	probably damaging	0.99
R8487:Vmn1r19	UTSW	6	57405181	missense	probably benign	0.03
R8812:Vmn1r19	UTSW	6	57404451	start gained	probably benign
R8907:Vmn1r19	UTSW	6	57405006	missense	probably benign
R8976:Vmn1r19	UTSW	6	57404734	missense	probably benign	0.01
R9277:Vmn1r19	UTSW	6	57405337	missense	unknown

Posted On

2015-04-16