Incidental Mutation 'IGL02677:Csnka2ip'
ID 303199
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Csnka2ip
Ensembl Gene ENSMUSG00000068167
Gene Name casein kinase 2, alpha prime interacting protein
Synonyms Ckt2
Accession Numbers
Essential gene? Probably non essential (E-score: 0.147) question?
Stock # IGL02677
Quality Score
Chromosome 16
Chromosomal Location 64298173-64422694 bp(-) (GRCm39)
Type of Mutation missense
DNA Base Change (assembly) A to G at 64298675 bp (GRCm39)
Zygosity Heterozygous
Amino Acid Change Leucine to Proline at position 119 (L119P)
Ref Sequence ENSEMBL: ENSMUSP00000086692 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000089279] [ENSMUST00000209382]
AlphaFold Q8CH19
Predicted Effect probably damaging
Transcript: ENSMUST00000089279
AA Change: L119P

PolyPhen 2 Score 0.993 (Sensitivity: 0.70; Specificity: 0.97)
SMART Domains Protein: ENSMUSP00000086692
Gene: ENSMUSG00000068167
AA Change: L119P

low complexity region 164 182 N/A INTRINSIC
low complexity region 186 201 N/A INTRINSIC
Predicted Effect unknown
Transcript: ENSMUST00000209382
AA Change: L563P
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 48 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
4931406B18Rik G T 7: 43,150,519 (GRCm39) Y84* probably null Het
Adam5 A G 8: 25,302,395 (GRCm39) probably benign Het
Aipl1 T C 11: 71,920,222 (GRCm39) E282G possibly damaging Het
Akp3 A G 1: 87,052,994 (GRCm39) D61G probably damaging Het
Anpep A G 7: 79,488,478 (GRCm39) S451P probably damaging Het
Ddx19a T C 8: 111,716,241 (GRCm39) E53G probably benign Het
Ddx50 C T 10: 62,452,072 (GRCm39) R116Q unknown Het
Ddx60 A T 8: 62,441,166 (GRCm39) E1078D probably damaging Het
Dpy19l1 T C 9: 24,396,368 (GRCm39) D116G probably damaging Het
Dsg4 A G 18: 20,597,933 (GRCm39) T668A possibly damaging Het
Dspp A G 5: 104,323,843 (GRCm39) T329A possibly damaging Het
Eftud2 T C 11: 102,737,440 (GRCm39) T554A probably damaging Het
Enpp1 T C 10: 24,555,083 (GRCm39) probably benign Het
Ext2 A T 2: 93,537,590 (GRCm39) F599I probably damaging Het
Fahd1 A T 17: 25,068,504 (GRCm39) I191N probably damaging Het
Fcrl2 A T 3: 87,166,694 (GRCm39) S100T probably benign Het
Fras1 T A 5: 96,692,883 (GRCm39) C181S probably damaging Het
Garre1 T A 7: 33,941,834 (GRCm39) probably benign Het
Gcnt4 A G 13: 97,083,741 (GRCm39) I346V probably benign Het
Gfra1 G A 19: 58,441,787 (GRCm39) T48I probably damaging Het
Kcnma1 A G 14: 23,513,224 (GRCm39) Y392H probably damaging Het
Klc2 T C 19: 5,161,696 (GRCm39) Y298C probably damaging Het
Lamb3 G A 1: 193,021,830 (GRCm39) V1011I probably benign Het
Ldb1 T C 19: 46,024,594 (GRCm39) probably benign Het
Mcph1 A G 8: 18,675,609 (GRCm39) K11E probably damaging Het
Myc A G 15: 61,861,513 (GRCm39) H374R probably damaging Het
Myom1 A G 17: 71,391,344 (GRCm39) Y853C probably damaging Het
Or4k38 A T 2: 111,166,147 (GRCm39) I92N probably damaging Het
Pakap C T 4: 57,856,263 (GRCm39) P572S probably benign Het
Pclo A G 5: 14,726,943 (GRCm39) probably benign Het
Pde3a G A 6: 141,350,898 (GRCm39) probably benign Het
Per1 T C 11: 68,997,486 (GRCm39) V887A probably benign Het
Prokr1 G A 6: 87,565,350 (GRCm39) probably benign Het
Rb1cc1 A G 1: 6,319,643 (GRCm39) I1021V probably benign Het
Ryr1 T C 7: 28,810,033 (GRCm39) E344G probably benign Het
Sec24c A T 14: 20,739,710 (GRCm39) D529V probably damaging Het
Slc1a6 T C 10: 78,624,898 (GRCm39) V101A probably damaging Het
Srrm1 G A 4: 135,052,415 (GRCm39) P658L unknown Het
Tap2 G A 17: 34,431,021 (GRCm39) V374M probably benign Het
Tex15 T A 8: 34,061,108 (GRCm39) D179E probably benign Het
Tmem8b T C 4: 43,686,092 (GRCm39) L241P probably damaging Het
Tmprss11g T C 5: 86,640,149 (GRCm39) D160G probably benign Het
Trim30a C T 7: 104,085,120 (GRCm39) C30Y probably damaging Het
Ttn A G 2: 76,601,840 (GRCm39) probably benign Het
Ush2a A G 1: 188,466,882 (GRCm39) R2849G probably damaging Het
Usp5 A G 6: 124,796,389 (GRCm39) V570A probably damaging Het
Vipr1 T C 9: 121,489,349 (GRCm39) probably benign Het
Zc2hc1c A C 12: 85,336,850 (GRCm39) D169A probably benign Het
Other mutations in Csnka2ip
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02039:Csnka2ip APN 16 64,298,957 (GRCm39) missense probably damaging 0.99
G1Funyon:Csnka2ip UTSW 16 64,299,354 (GRCm39) missense unknown
R0593:Csnka2ip UTSW 16 64,298,975 (GRCm39) missense probably damaging 0.99
R1075:Csnka2ip UTSW 16 64,298,310 (GRCm39) nonsense probably null
R1698:Csnka2ip UTSW 16 64,298,422 (GRCm39) nonsense probably null
R1815:Csnka2ip UTSW 16 64,298,855 (GRCm39) missense probably benign
R6446:Csnka2ip UTSW 16 64,299,744 (GRCm39) nonsense probably null
R6709:Csnka2ip UTSW 16 64,298,932 (GRCm39) missense possibly damaging 0.92
R6937:Csnka2ip UTSW 16 64,299,058 (GRCm39) utr 5 prime probably benign
R6999:Csnka2ip UTSW 16 64,298,933 (GRCm39) missense unknown
R7013:Csnka2ip UTSW 16 64,298,780 (GRCm39) missense unknown
R7103:Csnka2ip UTSW 16 64,299,120 (GRCm39) missense unknown
R7395:Csnka2ip UTSW 16 64,299,803 (GRCm39) missense
R7816:Csnka2ip UTSW 16 64,299,852 (GRCm39) unclassified probably benign
R8301:Csnka2ip UTSW 16 64,299,354 (GRCm39) missense unknown
R8416:Csnka2ip UTSW 16 64,300,295 (GRCm39) missense
R8946:Csnka2ip UTSW 16 64,300,667 (GRCm39) splice site probably benign
R9203:Csnka2ip UTSW 16 64,298,630 (GRCm39) missense unknown
R9479:Csnka2ip UTSW 16 64,298,262 (GRCm39) missense unknown
R9774:Csnka2ip UTSW 16 64,299,093 (GRCm39) missense unknown
R9799:Csnka2ip UTSW 16 64,298,672 (GRCm39) missense unknown
Posted On 2015-04-16