Incidental Mutation 'IGL02679:Spata21'
ID303316
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Spata21
Ensembl Gene ENSMUSG00000045004
Gene Namespermatogenesis associated 21
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.076) question?
Stock #IGL02679
Quality Score
Status
Chromosome4
Chromosomal Location141088333-141112760 bp(+) (GRCm38)
Type of Mutationunclassified
DNA Base Change (assembly) T to C at 141111265 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000115949 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000051907] [ENSMUST00000102487] [ENSMUST00000148204]
Predicted Effect noncoding transcript
Transcript: ENSMUST00000039939
SMART Domains Protein: ENSMUSP00000035712
Gene: ENSMUSG00000040842

DomainStartEndE-ValueType
Pfam:SUZ 36 87 7.7e-19 PFAM
Pfam:SUZ-C 99 132 2.2e-15 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000051907
SMART Domains Protein: ENSMUSP00000053080
Gene: ENSMUSG00000045004

DomainStartEndE-ValueType
low complexity region 21 34 N/A INTRINSIC
low complexity region 245 251 N/A INTRINSIC
low complexity region 319 335 N/A INTRINSIC
SCOP:d1mr8a_ 428 494 7e-13 SMART
PDB:2RRT|A 432 494 2e-7 PDB
low complexity region 524 540 N/A INTRINSIC
Predicted Effect noncoding transcript
Transcript: ENSMUST00000094549
SMART Domains Protein: ENSMUSP00000092128
Gene: ENSMUSG00000040842

DomainStartEndE-ValueType
Pfam:SUZ 37 88 7.9e-19 PFAM
Pfam:SUZ-C 100 133 2.2e-15 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000102487
SMART Domains Protein: ENSMUSP00000099545
Gene: ENSMUSG00000040842

DomainStartEndE-ValueType
low complexity region 2 16 N/A INTRINSIC
Pfam:SUZ 56 107 1.4e-17 PFAM
Pfam:SUZ-C 120 151 1.1e-12 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000148204
SMART Domains Protein: ENSMUSP00000115949
Gene: ENSMUSG00000040842

DomainStartEndE-ValueType
Pfam:SUZ 50 101 1.7e-18 PFAM
Pfam:SUZ-C 113 146 1.3e-14 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000181353
Predicted Effect noncoding transcript
Transcript: ENSMUST00000181450
SMART Domains Protein: ENSMUSP00000138075
Gene: ENSMUSG00000097620

DomainStartEndE-ValueType
low complexity region 22 28 N/A INTRINSIC
Predicted Effect noncoding transcript
Transcript: ENSMUST00000187076
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 47 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
4930442H23Rik T A 10: 81,182,979 probably benign Het
Adam5 A T 8: 24,806,526 Y302N probably damaging Het
Ankrd34c A T 9: 89,730,079 Y70N probably damaging Het
Asph G A 4: 9,601,349 P190S possibly damaging Het
Atp6v1h T C 1: 5,124,302 C235R probably damaging Het
Brwd1 A G 16: 96,002,823 L2049P probably benign Het
Capn2 T A 1: 182,472,584 I614F probably benign Het
Ccdc126 T A 6: 49,334,061 M1K probably null Het
Cdh9 T C 15: 16,832,230 I401T probably damaging Het
Cep57l1 T C 10: 41,729,386 E121G probably damaging Het
Cfap46 A G 7: 139,614,470 I2276T probably damaging Het
Cnnm3 T C 1: 36,520,158 S490P probably benign Het
D430041D05Rik C T 2: 104,230,305 V731I possibly damaging Het
Fgf3 C A 7: 144,840,750 N100K probably damaging Het
Gas7 G A 11: 67,675,727 probably null Het
Gfm1 C T 3: 67,474,767 P725S possibly damaging Het
Gimap4 T A 6: 48,690,495 C61* probably null Het
Greb1 C T 12: 16,708,723 R664Q probably damaging Het
Kpnb1 T A 11: 97,177,260 I295F possibly damaging Het
Lamc3 A G 2: 31,945,398 E1577G probably benign Het
Lrrk1 C T 7: 66,274,872 V235M probably damaging Het
Mipol1 T A 12: 57,306,043 V56E possibly damaging Het
Mycbp2 T C 14: 103,205,185 I1927V probably benign Het
Ncaph A T 2: 127,124,864 N223K possibly damaging Het
Nipbl A G 15: 8,295,553 M2542T probably benign Het
Nolc1 C A 19: 46,083,029 probably benign Het
Olfr16 G A 1: 172,957,176 C127Y probably damaging Het
Olfr555 A G 7: 102,659,177 M119V possibly damaging Het
Pkhd1l1 T C 15: 44,530,045 probably null Het
Ppat A T 5: 76,919,469 C306S probably benign Het
Ptpn13 A T 5: 103,569,454 M1821L possibly damaging Het
Rabl3 C T 16: 37,541,925 S42L probably damaging Het
Rbm12 C T 2: 156,095,560 probably benign Het
Rfx3 G A 19: 27,849,737 H150Y possibly damaging Het
Rngtt A G 4: 33,356,098 M312V possibly damaging Het
Slc10a2 T A 8: 5,098,499 T149S probably damaging Het
Stx8 G T 11: 67,969,772 W6C probably damaging Het
Tcn2 T C 11: 3,927,504 E48G possibly damaging Het
Tctex1d2 T C 16: 32,425,307 V107A possibly damaging Het
Tecpr1 A T 5: 144,206,546 N670K probably benign Het
Tldc1 A T 8: 119,772,410 D114E probably benign Het
Tmem255b G A 8: 13,457,055 M240I probably benign Het
Ubr4 G A 4: 139,459,134 E651K probably damaging Het
Ubr5 T C 15: 38,002,314 T1498A probably benign Het
Vmn2r95 G A 17: 18,443,854 C445Y probably damaging Het
Zfp429 T A 13: 67,399,736 probably benign Het
Zfp804b T G 5: 6,771,392 D557A possibly damaging Het
Other mutations in Spata21
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00502:Spata21 APN 4 141111364 unclassified probably null
R1772:Spata21 UTSW 4 141111296 missense possibly damaging 0.79
R1894:Spata21 UTSW 4 141111381 missense possibly damaging 0.53
R1950:Spata21 UTSW 4 141111405 missense probably damaging 0.99
R2015:Spata21 UTSW 4 141107329 nonsense probably null
R2093:Spata21 UTSW 4 141096966 missense probably benign 0.04
R2911:Spata21 UTSW 4 141103082 missense possibly damaging 0.46
R4809:Spata21 UTSW 4 141097120 critical splice donor site probably null
R4897:Spata21 UTSW 4 141104950 missense probably damaging 0.99
R4907:Spata21 UTSW 4 141097121 critical splice donor site probably null
R4921:Spata21 UTSW 4 141112091 missense probably damaging 1.00
R5269:Spata21 UTSW 4 141103021 missense probably damaging 1.00
R5380:Spata21 UTSW 4 141107185 missense probably damaging 1.00
R5602:Spata21 UTSW 4 141096899 missense probably benign
R6982:Spata21 UTSW 4 141096873 missense possibly damaging 0.71
R7503:Spata21 UTSW 4 141095303 missense probably benign 0.05
R7809:Spata21 UTSW 4 141104043 missense probably null 0.83
R8072:Spata21 UTSW 4 141112006 nonsense probably null
Z1177:Spata21 UTSW 4 141098002 missense probably damaging 1.00
Posted On2015-04-16