Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02683:Tex44'

303434

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Tex44

Ensembl Gene

ENSMUSG00000036574

Gene Name

testis expressed 44

Synonyms

1700019O17Rik

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.055) question?

Stock #

IGL02683

Quality Score

Status

Chromosome

Chromosomal Location

86354051-86355771 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 86355465 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Aspartic acid to Glycine at position 458 (D458G)

Ref Sequence

ENSEMBL: ENSMUSP00000136430 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000046004] [ENSMUST00000212541]

AlphaFold

Q9DA60

Predicted Effect

probably benign
Transcript: ENSMUST00000046004
AA Change: D458G

PolyPhen 2 Score 0.010 (Sensitivity: 0.96; Specificity: 0.77)

SMART Domains

Protein: ENSMUSP00000136430
Gene: ENSMUSG00000036574
AA Change: D458G

Domain	Start	End	E-Value	Type
internal_repeat_1	60	129	5.56e-9	PROSPERO
Pfam:DUF4678	147	529	4.3e-99	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000212541

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 43 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Aars1	T	C	8: 111,779,163 (GRCm39)		probably benign	Het
Abhd3	A	G	18: 10,658,790 (GRCm39)	S215P	probably damaging	Het
Adam20	G	A	8: 41,248,621 (GRCm39)	V244M	probably damaging	Het
Akr1c21	A	C	13: 4,626,312 (GRCm39)	D112A	probably damaging	Het
Ano6	A	T	15: 95,846,193 (GRCm39)	Y498F	probably damaging	Het
Aspscr1	T	C	11: 120,592,052 (GRCm39)	F263S	probably damaging	Het
Capn11	A	G	17: 45,964,517 (GRCm39)	F100S	probably damaging	Het
Cd63	T	C	10: 128,746,299 (GRCm39)	C9R	probably damaging	Het
Cenpj	T	C	14: 56,790,409 (GRCm39)	K547E	possibly damaging	Het
Clasp1	A	G	1: 118,466,996 (GRCm39)	D793G	probably benign	Het
Cmya5	G	A	13: 93,227,505 (GRCm39)	Q2528*	probably null	Het
Crybg1	A	G	10: 43,865,212 (GRCm39)	S1422P	possibly damaging	Het
Csgalnact1	C	A	8: 68,854,144 (GRCm39)	G219V	probably damaging	Het
Dnal1	G	A	12: 84,185,128 (GRCm39)	G178D	probably damaging	Het
E2f7	T	C	10: 110,618,320 (GRCm39)	M795T	probably benign	Het
Glipr1l2	T	C	10: 111,919,381 (GRCm39)	V34A	probably benign	Het
Gsdmc2	C	T	15: 63,705,261 (GRCm39)	V151M	probably damaging	Het
Htr7	T	C	19: 35,937,762 (GRCm39)	T448A	probably benign	Het
Kcnj5	T	C	9: 32,229,076 (GRCm39)	T41A	possibly damaging	Het
Kcnt1	T	C	2: 25,790,937 (GRCm39)	M12T	possibly damaging	Het
Kif1c	G	A	11: 70,617,278 (GRCm39)	A871T	possibly damaging	Het
Map3k10	T	C	7: 27,358,362 (GRCm39)	K571R	probably damaging	Het
Med23	C	A	10: 24,746,615 (GRCm39)	A45E	probably benign	Het
Nudt5	C	A	2: 5,868,412 (GRCm39)	S103R	probably damaging	Het
Or9m1	T	A	2: 87,733,448 (GRCm39)	T191S	possibly damaging	Het
Parp3	A	G	9: 106,350,384 (GRCm39)	S369P	possibly damaging	Het
Plxna4	A	T	6: 32,494,541 (GRCm39)	L25Q	probably benign	Het
Pon2	A	G	6: 5,269,062 (GRCm39)	V204A	probably damaging	Het
Ppfia1	A	G	7: 144,067,095 (GRCm39)	M463T	probably damaging	Het
Ppp1r14d	T	C	2: 119,049,303 (GRCm39)	E95G	probably damaging	Het
Pramel18	T	C	4: 101,767,551 (GRCm39)	S267P	probably benign	Het
Prrc2a	A	G	17: 35,374,969 (GRCm39)	V1227A	probably benign	Het
Rabgap1	T	A	2: 37,392,951 (GRCm39)	W536R	probably damaging	Het
Slco6d1	A	G	1: 98,408,397 (GRCm39)	N431S	probably benign	Het
Spen	C	T	4: 141,198,956 (GRCm39)	V3224I	probably benign	Het
Srrm1	G	A	4: 135,052,415 (GRCm39)	P658L	unknown	Het
Ssh2	A	G	11: 77,289,082 (GRCm39)	D88G	probably damaging	Het
Stat5b	T	G	11: 100,695,772 (GRCm39)	K70T	probably benign	Het
Tut1	T	A	19: 8,942,622 (GRCm39)	C570S	probably benign	Het
Usp42	T	C	5: 143,701,101 (GRCm39)	E974G	possibly damaging	Het
Vezf1	A	T	11: 87,967,153 (GRCm39)	Q310L	probably benign	Het
Vmn2r83	A	T	10: 79,327,115 (GRCm39)	R574S	probably benign	Het
Zfp664	T	C	5: 124,963,386 (GRCm39)	V260A	probably benign	Het

Other mutations in Tex44

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL02579:Tex44	APN	1	86,354,169 (GRCm39)	missense	probably benign	0.00
R0589:Tex44	UTSW	1	86,355,453 (GRCm39)	missense	probably damaging	1.00
R1077:Tex44	UTSW	1	86,354,777 (GRCm39)	missense	probably benign	0.00
R1468:Tex44	UTSW	1	86,354,834 (GRCm39)	missense	probably benign	0.16
R1468:Tex44	UTSW	1	86,354,834 (GRCm39)	missense	probably benign	0.16
R1483:Tex44	UTSW	1	86,354,908 (GRCm39)	missense	probably damaging	0.99
R1485:Tex44	UTSW	1	86,355,640 (GRCm39)	missense	possibly damaging	0.72
R1527:Tex44	UTSW	1	86,355,368 (GRCm39)	missense	probably benign	0.01
R2058:Tex44	UTSW	1	86,354,728 (GRCm39)	missense	probably damaging	1.00
R2126:Tex44	UTSW	1	86,354,811 (GRCm39)	missense	probably benign	0.04
R4394:Tex44	UTSW	1	86,355,489 (GRCm39)	missense	probably benign	0.16
R4524:Tex44	UTSW	1	86,355,298 (GRCm39)	missense	probably benign	0.03
R6191:Tex44	UTSW	1	86,354,306 (GRCm39)	unclassified	probably benign
R6658:Tex44	UTSW	1	86,354,751 (GRCm39)	missense	probably benign	0.01
R6731:Tex44	UTSW	1	86,354,207 (GRCm39)	missense	probably benign	0.04
R7526:Tex44	UTSW	1	86,354,237 (GRCm39)	missense	probably benign	0.33
R7625:Tex44	UTSW	1	86,354,459 (GRCm39)	nonsense	probably null
R8251:Tex44	UTSW	1	86,354,936 (GRCm39)	missense	probably benign	0.05
R8446:Tex44	UTSW	1	86,354,696 (GRCm39)	missense	possibly damaging	0.92
R9369:Tex44	UTSW	1	86,355,383 (GRCm39)	missense	probably damaging	1.00
R9625:Tex44	UTSW	1	86,354,253 (GRCm39)	missense	unknown

Posted On

2015-04-16