Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02683:Zfp664'

303458

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Zfp664

Ensembl Gene

ENSMUSG00000079215

Gene Name

zinc finger protein 664

Synonyms

D930038J03Rik

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

IGL02683

Quality Score

Status

Chromosome

Chromosomal Location

124939758-124965694 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 124963386 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Valine to Alanine at position 260 (V260A)

Ref Sequence

ENSEMBL: ENSMUSP00000107048 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000111417]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000111417
AA Change: V260A

PolyPhen 2 Score 0.030 (Sensitivity: 0.95; Specificity: 0.82)

SMART Domains

Protein: ENSMUSP00000107048
Gene: ENSMUSG00000079215
AA Change: V260A

Domain	Start	End	E-Value	Type
ZnF_C2H2	3	25	2.57e-3	SMART
ZnF_C2H2	31	53	7.55e-1	SMART
ZnF_C2H2	59	81	5.99e-4	SMART
ZnF_C2H2	87	109	3.21e-4	SMART
ZnF_C2H2	115	137	4.54e-4	SMART
ZnF_C2H2	143	165	4.79e-3	SMART
ZnF_C2H2	171	193	8.34e-3	SMART
ZnF_C2H2	199	221	6.23e-2	SMART
ZnF_C2H2	227	249	7.9e-4	SMART

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000130616

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000134463

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000134473

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000141533

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 43 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Aars1	T	C	8: 111,779,163 (GRCm39)		probably benign	Het
Abhd3	A	G	18: 10,658,790 (GRCm39)	S215P	probably damaging	Het
Adam20	G	A	8: 41,248,621 (GRCm39)	V244M	probably damaging	Het
Akr1c21	A	C	13: 4,626,312 (GRCm39)	D112A	probably damaging	Het
Ano6	A	T	15: 95,846,193 (GRCm39)	Y498F	probably damaging	Het
Aspscr1	T	C	11: 120,592,052 (GRCm39)	F263S	probably damaging	Het
Capn11	A	G	17: 45,964,517 (GRCm39)	F100S	probably damaging	Het
Cd63	T	C	10: 128,746,299 (GRCm39)	C9R	probably damaging	Het
Cenpj	T	C	14: 56,790,409 (GRCm39)	K547E	possibly damaging	Het
Clasp1	A	G	1: 118,466,996 (GRCm39)	D793G	probably benign	Het
Cmya5	G	A	13: 93,227,505 (GRCm39)	Q2528*	probably null	Het
Crybg1	A	G	10: 43,865,212 (GRCm39)	S1422P	possibly damaging	Het
Csgalnact1	C	A	8: 68,854,144 (GRCm39)	G219V	probably damaging	Het
Dnal1	G	A	12: 84,185,128 (GRCm39)	G178D	probably damaging	Het
E2f7	T	C	10: 110,618,320 (GRCm39)	M795T	probably benign	Het
Glipr1l2	T	C	10: 111,919,381 (GRCm39)	V34A	probably benign	Het
Gsdmc2	C	T	15: 63,705,261 (GRCm39)	V151M	probably damaging	Het
Htr7	T	C	19: 35,937,762 (GRCm39)	T448A	probably benign	Het
Kcnj5	T	C	9: 32,229,076 (GRCm39)	T41A	possibly damaging	Het
Kcnt1	T	C	2: 25,790,937 (GRCm39)	M12T	possibly damaging	Het
Kif1c	G	A	11: 70,617,278 (GRCm39)	A871T	possibly damaging	Het
Map3k10	T	C	7: 27,358,362 (GRCm39)	K571R	probably damaging	Het
Med23	C	A	10: 24,746,615 (GRCm39)	A45E	probably benign	Het
Nudt5	C	A	2: 5,868,412 (GRCm39)	S103R	probably damaging	Het
Or9m1	T	A	2: 87,733,448 (GRCm39)	T191S	possibly damaging	Het
Parp3	A	G	9: 106,350,384 (GRCm39)	S369P	possibly damaging	Het
Plxna4	A	T	6: 32,494,541 (GRCm39)	L25Q	probably benign	Het
Pon2	A	G	6: 5,269,062 (GRCm39)	V204A	probably damaging	Het
Ppfia1	A	G	7: 144,067,095 (GRCm39)	M463T	probably damaging	Het
Ppp1r14d	T	C	2: 119,049,303 (GRCm39)	E95G	probably damaging	Het
Pramel18	T	C	4: 101,767,551 (GRCm39)	S267P	probably benign	Het
Prrc2a	A	G	17: 35,374,969 (GRCm39)	V1227A	probably benign	Het
Rabgap1	T	A	2: 37,392,951 (GRCm39)	W536R	probably damaging	Het
Slco6d1	A	G	1: 98,408,397 (GRCm39)	N431S	probably benign	Het
Spen	C	T	4: 141,198,956 (GRCm39)	V3224I	probably benign	Het
Srrm1	G	A	4: 135,052,415 (GRCm39)	P658L	unknown	Het
Ssh2	A	G	11: 77,289,082 (GRCm39)	D88G	probably damaging	Het
Stat5b	T	G	11: 100,695,772 (GRCm39)	K70T	probably benign	Het
Tex44	A	G	1: 86,355,465 (GRCm39)	D458G	probably benign	Het
Tut1	T	A	19: 8,942,622 (GRCm39)	C570S	probably benign	Het
Usp42	T	C	5: 143,701,101 (GRCm39)	E974G	possibly damaging	Het
Vezf1	A	T	11: 87,967,153 (GRCm39)	Q310L	probably benign	Het
Vmn2r83	A	T	10: 79,327,115 (GRCm39)	R574S	probably benign	Het

Other mutations in Zfp664

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01556:Zfp664	APN	5	124,963,252 (GRCm39)	nonsense	probably null
R0394:Zfp664	UTSW	5	124,963,129 (GRCm39)	nonsense	probably null
R0629:Zfp664	UTSW	5	124,962,659 (GRCm39)	missense	probably damaging	0.99
R1400:Zfp664	UTSW	5	124,963,217 (GRCm39)	missense	unknown
R6052:Zfp664	UTSW	5	124,963,250 (GRCm39)	missense	unknown
R6058:Zfp664	UTSW	5	124,963,042 (GRCm39)	nonsense	probably null
R6529:Zfp664	UTSW	5	124,963,352 (GRCm39)	missense	probably damaging	1.00
R7031:Zfp664	UTSW	5	124,963,070 (GRCm39)	missense	probably benign	0.06
R7752:Zfp664	UTSW	5	124,962,839 (GRCm39)	nonsense	probably null
R7901:Zfp664	UTSW	5	124,962,839 (GRCm39)	nonsense	probably null
R8434:Zfp664	UTSW	5	124,962,827 (GRCm39)	missense	possibly damaging	0.90
R8686:Zfp664	UTSW	5	124,963,133 (GRCm39)	missense	possibly damaging	0.61

Posted On

2015-04-16