Incidental Mutation 'IGL02687:Gm7995'
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm7995
Ensembl Gene ENSMUSG00000094157
Gene Namepredicted gene 7995
Accession Numbers
Is this an essential gene? Not available question?
Stock #IGL02687
Quality Score
Chromosomal Location42310210-42325394 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to G at 42311405 bp
Amino Acid Change Isoleucine to Valine at position 81 (I81V)
Ref Sequence ENSEMBL: ENSMUSP00000087222 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000089789]
Predicted Effect probably damaging
Transcript: ENSMUST00000089789
AA Change: I81V

PolyPhen 2 Score 0.979 (Sensitivity: 0.75; Specificity: 0.96)
SMART Domains Protein: ENSMUSP00000087222
Gene: ENSMUSG00000094157
AA Change: I81V

Pfam:Takusan 3 86 2.4e-35 PFAM
coiled coil region 101 134 N/A INTRINSIC
Predicted Effect unknown
Transcript: ENSMUST00000171967
AA Change: I80V
SMART Domains Protein: ENSMUSP00000132956
Gene: ENSMUSG00000094157
AA Change: I80V

Pfam:Takusan 5 85 2.5e-27 PFAM
coiled coil region 100 133 N/A INTRINSIC
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 28 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Abca9 A G 11: 110,114,232 V1315A probably damaging Het
Adam2 A T 14: 66,069,190 C117S probably damaging Het
Arpp21 T A 9: 112,065,815 R792* probably null Het
Atp13a3 A G 16: 30,337,551 M938T probably damaging Het
Atp6v0a2 C T 5: 124,714,142 T545M possibly damaging Het
BC051019 T C 7: 109,716,352 D84G possibly damaging Het
Bdkrb1 T A 12: 105,604,832 L219H probably damaging Het
Cdc45 C T 16: 18,798,729 M200I probably benign Het
Cfap46 T C 7: 139,607,201 D2415G probably damaging Het
Csgalnact2 T C 6: 118,124,415 probably null Het
Cyp4a29 T C 4: 115,251,200 C374R probably damaging Het
Dgkb C A 12: 38,630,629 P776Q possibly damaging Het
Duox1 A T 2: 122,336,415 K1005M probably damaging Het
Dusp6 C A 10: 99,266,182 F343L probably damaging Het
Espl1 C T 15: 102,313,178 probably benign Het
Filip1l T C 16: 57,571,127 S455P probably benign Het
Lingo4 T C 3: 94,402,097 L114P probably damaging Het
Mfsd6 A G 1: 52,708,675 S344P probably damaging Het
Mpc1 G A 17: 8,297,143 S162N probably benign Het
Myh11 T A 16: 14,212,618 K1143* probably null Het
Nek10 T C 14: 14,840,570 L152P probably damaging Het
Olfr598 C T 7: 103,329,400 R305* probably null Het
Olfr815 T C 10: 129,902,102 M203V probably benign Het
Olfr995 T A 2: 85,438,586 N191Y possibly damaging Het
Rab11a A G 9: 64,726,698 I119T probably damaging Het
Spata31d1d T A 13: 59,727,864 H619L possibly damaging Het
Ulk4 A T 9: 121,192,662 V661E possibly damaging Het
Vmn1r199 T C 13: 22,382,791 V85A possibly damaging Het
Other mutations in Gm7995
AlleleSourceChrCoordTypePredicted EffectPPH Score
R4883:Gm7995 UTSW 14 42311426 missense probably damaging 1.00
R5273:Gm7995 UTSW 14 42311456 missense probably damaging 1.00
R6490:Gm7995 UTSW 14 42311370 missense probably benign 0.39
R7448:Gm7995 UTSW 14 42310345 missense
R7505:Gm7995 UTSW 14 42310357 missense
R7647:Gm7995 UTSW 14 42311351 missense possibly damaging 0.89
Posted On2015-04-16