Incidental Mutation 'IGL02701:Zmynd12'
ID 304150
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Zmynd12
Ensembl Gene ENSMUSG00000070806
Gene Name zinc finger, MYND domain containing 12
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.061) question?
Stock # IGL02701
Quality Score
Status
Chromosome 4
Chromosomal Location 119422814-119467444 bp(+) (GRCm38)
Type of Mutation splice site
DNA Base Change (assembly) G to T at 119444755 bp (GRCm38)
Zygosity Heterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000092414 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000094819]
AlphaFold A2BGJ5
Predicted Effect probably benign
Transcript: ENSMUST00000094819
SMART Domains Protein: ENSMUSP00000092414
Gene: ENSMUSG00000070806

DomainStartEndE-ValueType
Pfam:zf-MYND 17 54 1.2e-10 PFAM
low complexity region 70 87 N/A INTRINSIC
Blast:TPR 88 121 2e-14 BLAST
Pfam:TPR_8 130 157 3.9e-3 PFAM
Pfam:TPR_8 172 196 1.5e-2 PFAM
Blast:TPR 214 247 2e-13 BLAST
low complexity region 305 319 N/A INTRINSIC
Predicted Effect noncoding transcript
Transcript: ENSMUST00000129150
Predicted Effect noncoding transcript
Transcript: ENSMUST00000134147
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 39 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
1700015F17Rik A G 5: 5,466,623 probably null Het
4833423E24Rik A G 2: 85,484,169 L480P probably damaging Het
Arhgap21 A G 2: 20,892,091 C125R probably damaging Het
Blmh A G 11: 76,971,910 D383G probably benign Het
Brca1 T C 11: 101,525,235 E691G probably damaging Het
Chrm3 G A 13: 9,878,464 R179* probably null Het
Cnrip1 A G 11: 17,078,415 T116A probably benign Het
Csmd2 T C 4: 128,496,141 V2223A probably benign Het
Dalrd3 T A 9: 108,572,284 V143D possibly damaging Het
Ddx60 A T 8: 61,979,341 I886L probably damaging Het
Dennd4a T C 9: 64,897,353 F1325L possibly damaging Het
Dnmt3l A T 10: 78,055,022 T253S probably benign Het
Gde1 T A 7: 118,698,637 T9S probably damaging Het
Ggcx T A 6: 72,418,472 probably benign Het
Gm813 G A 16: 58,615,807 S51L probably benign Het
Hspg2 C T 4: 137,557,174 A3481V probably damaging Het
Igf1r T C 7: 68,201,249 Y931H possibly damaging Het
Ighv12-3 A C 12: 114,366,801 S25A probably damaging Het
Itga5 A C 15: 103,347,766 C920G probably damaging Het
Kmt5b A G 19: 3,796,681 D118G probably benign Het
Lrp1b T G 2: 41,246,017 N1647T possibly damaging Het
Lrrc71 T C 3: 87,741,772 E363G probably benign Het
Mapk1 A G 16: 17,015,906 Y41C probably benign Het
Mib1 T C 18: 10,747,357 V178A probably damaging Het
Olfr1022 A G 2: 85,869,458 I289V probably benign Het
Olfr159 A G 4: 43,770,366 I215T probably benign Het
Olfr472 A T 7: 107,903,442 T242S probably benign Het
Plb1 T C 5: 32,364,197 V1464A unknown Het
Plekhg5 T C 4: 152,103,022 S82P probably damaging Het
Plxna4 T C 6: 32,517,559 T41A probably benign Het
Ppip5k1 A C 2: 121,316,649 probably null Het
Rpl14 T C 9: 120,573,573 probably benign Het
Slc44a2 T C 9: 21,347,951 F554L probably benign Het
Slco1b2 T A 6: 141,685,545 V635E probably benign Het
Sv2a T A 3: 96,187,131 C261S probably damaging Het
Thbs2 T C 17: 14,683,361 I353V probably benign Het
Tspan4 G A 7: 141,492,028 V205M probably damaging Het
Vezf1 A T 11: 88,076,221 R93* probably null Het
Wwox T A 8: 114,706,368 V258D probably damaging Het
Other mutations in Zmynd12
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01603:Zmynd12 APN 4 119441920 critical splice donor site probably null
IGL02113:Zmynd12 APN 4 119433997 missense probably damaging 1.00
IGL03287:Zmynd12 APN 4 119453579 missense probably damaging 1.00
IGL03138:Zmynd12 UTSW 4 119422989 missense probably damaging 1.00
R4531:Zmynd12 UTSW 4 119422997 critical splice donor site probably null
R5078:Zmynd12 UTSW 4 119444850 missense probably damaging 1.00
R5687:Zmynd12 UTSW 4 119441901 missense probably damaging 0.96
R6995:Zmynd12 UTSW 4 119453575 missense probably benign 0.00
R7707:Zmynd12 UTSW 4 119444866 missense probably damaging 1.00
R8393:Zmynd12 UTSW 4 119448155 missense probably damaging 1.00
R8911:Zmynd12 UTSW 4 119437089 missense probably damaging 1.00
R8952:Zmynd12 UTSW 4 119444884 critical splice donor site probably null
X0019:Zmynd12 UTSW 4 119450368 missense probably benign 0.04
Z1176:Zmynd12 UTSW 4 119422877 unclassified probably benign
Posted On 2015-04-16