Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02701:Zmynd12'

304150

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Zmynd12

Ensembl Gene

ENSMUSG00000070806

Gene Name

zinc finger, MYND domain containing 12

Synonyms

Accession Numbers

Is this an essential gene?

Probably non essential (E-score: 0.061) question?

Stock #

IGL02701

Quality Score

Status

Chromosome

Chromosomal Location

119422814-119467444 bp(+) (GRCm38)

Type of Mutation

splice site

DNA Base Change (assembly)

G to T at 119444755 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000092414 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000094819]

AlphaFold

A2BGJ5

Predicted Effect

probably benign
Transcript: ENSMUST00000094819

SMART Domains

Protein: ENSMUSP00000092414
Gene: ENSMUSG00000070806

Domain	Start	End	E-Value	Type
Pfam:zf-MYND	17	54	1.2e-10	PFAM
low complexity region	70	87	N/A	INTRINSIC
Blast:TPR	88	121	2e-14	BLAST
Pfam:TPR_8	130	157	3.9e-3	PFAM
Pfam:TPR_8	172	196	1.5e-2	PFAM
Blast:TPR	214	247	2e-13	BLAST
low complexity region	305	319	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000129150

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000134147

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 39 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700015F17Rik	A	G	5: 5,466,623		probably null	Het
4833423E24Rik	A	G	2: 85,484,169	L480P	probably damaging	Het
Arhgap21	A	G	2: 20,892,091	C125R	probably damaging	Het
Blmh	A	G	11: 76,971,910	D383G	probably benign	Het
Brca1	T	C	11: 101,525,235	E691G	probably damaging	Het
Chrm3	G	A	13: 9,878,464	R179*	probably null	Het
Cnrip1	A	G	11: 17,078,415	T116A	probably benign	Het
Csmd2	T	C	4: 128,496,141	V2223A	probably benign	Het
Dalrd3	T	A	9: 108,572,284	V143D	possibly damaging	Het
Ddx60	A	T	8: 61,979,341	I886L	probably damaging	Het
Dennd4a	T	C	9: 64,897,353	F1325L	possibly damaging	Het
Dnmt3l	A	T	10: 78,055,022	T253S	probably benign	Het
Gde1	T	A	7: 118,698,637	T9S	probably damaging	Het
Ggcx	T	A	6: 72,418,472		probably benign	Het
Gm813	G	A	16: 58,615,807	S51L	probably benign	Het
Hspg2	C	T	4: 137,557,174	A3481V	probably damaging	Het
Igf1r	T	C	7: 68,201,249	Y931H	possibly damaging	Het
Ighv12-3	A	C	12: 114,366,801	S25A	probably damaging	Het
Itga5	A	C	15: 103,347,766	C920G	probably damaging	Het
Kmt5b	A	G	19: 3,796,681	D118G	probably benign	Het
Lrp1b	T	G	2: 41,246,017	N1647T	possibly damaging	Het
Lrrc71	T	C	3: 87,741,772	E363G	probably benign	Het
Mapk1	A	G	16: 17,015,906	Y41C	probably benign	Het
Mib1	T	C	18: 10,747,357	V178A	probably damaging	Het
Olfr1022	A	G	2: 85,869,458	I289V	probably benign	Het
Olfr159	A	G	4: 43,770,366	I215T	probably benign	Het
Olfr472	A	T	7: 107,903,442	T242S	probably benign	Het
Plb1	T	C	5: 32,364,197	V1464A	unknown	Het
Plekhg5	T	C	4: 152,103,022	S82P	probably damaging	Het
Plxna4	T	C	6: 32,517,559	T41A	probably benign	Het
Ppip5k1	A	C	2: 121,316,649		probably null	Het
Rpl14	T	C	9: 120,573,573		probably benign	Het
Slc44a2	T	C	9: 21,347,951	F554L	probably benign	Het
Slco1b2	T	A	6: 141,685,545	V635E	probably benign	Het
Sv2a	T	A	3: 96,187,131	C261S	probably damaging	Het
Thbs2	T	C	17: 14,683,361	I353V	probably benign	Het
Tspan4	G	A	7: 141,492,028	V205M	probably damaging	Het
Vezf1	A	T	11: 88,076,221	R93*	probably null	Het
Wwox	T	A	8: 114,706,368	V258D	probably damaging	Het

Other mutations in Zmynd12

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01603:Zmynd12	APN	4	119441920	critical splice donor site	probably null
IGL02113:Zmynd12	APN	4	119433997	missense	probably damaging	1.00
IGL03287:Zmynd12	APN	4	119453579	missense	probably damaging	1.00
IGL03138:Zmynd12	UTSW	4	119422989	missense	probably damaging	1.00
R4531:Zmynd12	UTSW	4	119422997	critical splice donor site	probably null
R5078:Zmynd12	UTSW	4	119444850	missense	probably damaging	1.00
R5687:Zmynd12	UTSW	4	119441901	missense	probably damaging	0.96
R6995:Zmynd12	UTSW	4	119453575	missense	probably benign	0.00
R7707:Zmynd12	UTSW	4	119444866	missense	probably damaging	1.00
R8393:Zmynd12	UTSW	4	119448155	missense	probably damaging	1.00
R8911:Zmynd12	UTSW	4	119437089	missense	probably damaging	1.00
R8952:Zmynd12	UTSW	4	119444884	critical splice donor site	probably null
X0019:Zmynd12	UTSW	4	119450368	missense	probably benign	0.04
Z1176:Zmynd12	UTSW	4	119422877	unclassified	probably benign

Posted On

2015-04-16