Incidental Mutation 'IGL02702:Prelid3a'
ID304185
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Prelid3a
Ensembl Gene ENSMUSG00000024530
Gene NamePRELI domain containing 3A
SynonymsA230074A19Rik, Slmo1
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.208) question?
Stock #IGL02702
Quality Score
Status
Chromosome18
Chromosomal Location67464849-67480581 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) T to A at 67473794 bp
ZygosityHeterozygous
Amino Acid Change Aspartic acid to Glutamic Acid at position 85 (D85E)
Ref Sequence ENSEMBL: ENSMUSP00000025411 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000025411]
Predicted Effect probably damaging
Transcript: ENSMUST00000025411
AA Change: D85E

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
SMART Domains Protein: ENSMUSP00000025411
Gene: ENSMUSG00000024530
AA Change: D85E

DomainStartEndE-ValueType
Pfam:PRELI 15 170 1.7e-52 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 34 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Abtb1 C T 6: 88,838,138 V337I probably benign Het
Adam11 G A 11: 102,777,038 V750I probably benign Het
Alms1 T C 6: 85,599,849 V129A probably benign Het
Cacna1d T A 14: 30,123,533 K560* probably null Het
Cntn1 A G 15: 92,291,601 probably benign Het
Cpne2 T C 8: 94,570,023 V530A probably benign Het
Fbxo21 T C 5: 118,000,510 L507P probably damaging Het
Fndc4 T C 5: 31,293,735 K204R probably damaging Het
Gnrhr G T 5: 86,182,269 N297K possibly damaging Het
Grin2b A G 6: 135,739,132 F729S probably damaging Het
Hdac3 C A 18: 37,941,094 R359L probably benign Het
Met T C 6: 17,534,143 S662P possibly damaging Het
Mphosph9 T A 5: 124,259,989 E1081D probably damaging Het
Mycbp2 T G 14: 103,220,124 T1546P probably benign Het
Nlrp9a T A 7: 26,564,956 M767K possibly damaging Het
Olfm5 A G 7: 104,154,357 Y300H probably damaging Het
Olfr911-ps1 T A 9: 38,524,560 V276D probably damaging Het
Pcf11 A T 7: 92,661,618 N178K possibly damaging Het
Polr3a T C 14: 24,470,877 I571M probably benign Het
Ppef2 T A 5: 92,231,819 R557W probably benign Het
Rb1cc1 A G 1: 6,240,023 E215G probably damaging Het
Rbm12 C T 2: 156,095,560 probably benign Het
Recql4 C T 15: 76,707,285 G501R probably damaging Het
Sema3e T C 5: 14,233,726 probably benign Het
Shisa6 A C 11: 66,219,962 L318V probably damaging Het
Slu7 T C 11: 43,438,892 probably benign Het
Spink12 T C 18: 44,104,769 V38A probably benign Het
Syne2 A G 12: 76,097,924 D1549G probably damaging Het
Tet1 A G 10: 62,879,752 V88A possibly damaging Het
Tmem200a C T 10: 25,993,603 G256D probably damaging Het
Ttn G T 2: 76,884,491 probably benign Het
Ugt2b34 T C 5: 86,892,891 I391V probably benign Het
Zfp292 A T 4: 34,809,415 L1215I probably benign Het
Zfp410 C A 12: 84,325,776 N125K probably damaging Het
Other mutations in Prelid3a
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL03059:Prelid3a APN 18 67476839 nonsense probably null
R2294:Prelid3a UTSW 18 67472871 missense probably damaging 1.00
R4112:Prelid3a UTSW 18 67472897 missense probably damaging 1.00
R4113:Prelid3a UTSW 18 67472897 missense probably damaging 1.00
R5553:Prelid3a UTSW 18 67477023 missense probably damaging 1.00
R5951:Prelid3a UTSW 18 67464941 missense probably benign
Posted On2015-04-16