Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02711:Ripor3'

304589

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Ripor3

Ensembl Gene

ENSMUSG00000074577

Gene Name

RIPOR family member 3

Synonyms

2310033K02Rik, Fam65c

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.069) question?

Stock #

IGL02711

Quality Score

Status

Chromosome

Chromosomal Location

167980164-168010618 bp(-) (GRCm38)

Type of Mutation

utr 5 prime

DNA Base Change (assembly)

T to G at 168006280 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000096672 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000099073]

AlphaFold

A1L3T7

Predicted Effect

probably benign
Transcript: ENSMUST00000099073

SMART Domains

Protein: ENSMUSP00000096672
Gene: ENSMUSG00000074577

Domain	Start	End	E-Value	Type
Pfam:PL48	19	363	3.5e-169	PFAM
low complexity region	414	423	N/A	INTRINSIC
low complexity region	445	455	N/A	INTRINSIC
low complexity region	496	513	N/A	INTRINSIC
low complexity region	582	602	N/A	INTRINSIC
SCOP:d1gw5a_	794	909	6e-7	SMART

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000123782

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000142374

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 41 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abcb1a	A	T	5: 8,723,245		probably null	Het
Adamts10	T	A	17: 33,538,272	M400K	probably damaging	Het
Adamts17	G	A	7: 67,052,040		probably benign	Het
Adh5	A	G	3: 138,454,673	K323E	probably damaging	Het
Angptl2	T	C	2: 33,228,243	W10R	probably benign	Het
Arhgap15	T	C	2: 44,116,662	F264L	possibly damaging	Het
Atp6v1g3	T	A	1: 138,283,681	L33Q	probably damaging	Het
Baz2b	A	T	2: 59,917,505		probably benign	Het
BC027072	T	C	17: 71,749,382	D1100G	probably benign	Het
Capn11	A	G	17: 45,632,415	F611S	probably damaging	Het
Cep152	T	A	2: 125,563,942	T1557S	possibly damaging	Het
Cep76	A	T	18: 67,638,336	S75R	probably benign	Het
Cps1	A	G	1: 67,212,517		probably benign	Het
Dbf4	G	T	5: 8,408,235	A199E	probably benign	Het
Gldc	C	T	19: 30,145,146		probably null	Het
Hspa14	G	A	2: 3,502,520	A117V	probably benign	Het
Igkv4-80	G	A	6: 69,016,817	P30L	probably damaging	Het
Itga2b	A	T	11: 102,465,725	W292R	possibly damaging	Het
Kansl1	A	T	11: 104,335,575	S982T	probably damaging	Het
Klhdc7b	A	T	15: 89,388,043	K1043*	probably null	Het
Kmt2a	A	T	9: 44,824,523		probably benign	Het
Krt86	T	C	15: 101,473,662	Y38H	probably damaging	Het
Lingo4	T	C	3: 94,403,393	I546T	probably benign	Het
Lrrk1	A	G	7: 66,330,767	S222P	probably damaging	Het
Lrrk2	T	C	15: 91,685,822	V178A	possibly damaging	Het
Maml2	T	C	9: 13,620,063	V191A	probably benign	Het
Msh3	T	C	13: 92,351,311	T133A	probably damaging	Het
Nck1	T	C	9: 100,508,620	D12G	probably damaging	Het
Nox4	T	C	7: 87,396,868	Y572H	probably damaging	Het
Nqo1	A	T	8: 107,392,931	L30Q	probably damaging	Het
Olfr994	A	T	2: 85,430,739	V30E	probably damaging	Het
Oxr1	A	G	15: 41,653,671		probably benign	Het
Pcdhb10	A	C	18: 37,412,726	D285A	possibly damaging	Het
Pclo	A	G	5: 14,522,308	N569S	unknown	Het
Ppfibp1	T	A	6: 147,026,238	Y794*	probably null	Het
Rpe65	C	A	3: 159,622,877	H441N	possibly damaging	Het
St14	A	G	9: 31,089,900	V845A	probably benign	Het
Tmem116	T	A	5: 121,487,741		probably benign	Het
Tnfrsf11b	A	T	15: 54,256,136	D147E	probably benign	Het
Ttn	C	A	2: 76,730,122	G27566*	probably null	Het
Zscan18	G	T	7: 12,775,117		probably benign	Het

Other mutations in Ripor3

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01356:Ripor3	APN	2	167993575	missense	probably benign	0.05
IGL01621:Ripor3	APN	2	167997252	missense	probably damaging	0.97
IGL01819:Ripor3	APN	2	167980843	missense	probably damaging	0.99
IGL01891:Ripor3	APN	2	167983151	missense	possibly damaging	0.95
IGL02110:Ripor3	APN	2	167994706	missense	possibly damaging	0.95
IGL02270:Ripor3	APN	2	167993496	missense	probably damaging	0.97
IGL02403:Ripor3	APN	2	167989330	missense	probably damaging	1.00
IGL02445:Ripor3	APN	2	167992762	splice site	probably benign
IGL02447:Ripor3	APN	2	167992830	missense	probably damaging	0.99
IGL03187:Ripor3	APN	2	167985668	missense	possibly damaging	0.64
IGL03304:Ripor3	APN	2	167980928	splice site	probably benign
R0062:Ripor3	UTSW	2	167984438	splice site	probably benign
R0062:Ripor3	UTSW	2	167984438	splice site	probably benign
R0233:Ripor3	UTSW	2	167992598	missense	probably damaging	1.00
R0233:Ripor3	UTSW	2	167992598	missense	probably damaging	1.00
R0387:Ripor3	UTSW	2	167983772	nonsense	probably null
R1457:Ripor3	UTSW	2	167992653	missense	probably damaging	1.00
R1481:Ripor3	UTSW	2	168000377	missense	possibly damaging	0.95
R1619:Ripor3	UTSW	2	167980845	missense	probably damaging	0.96
R2358:Ripor3	UTSW	2	167983865	splice site	probably benign
R2431:Ripor3	UTSW	2	167989795	missense	probably benign	0.06
R2943:Ripor3	UTSW	2	167983761	missense	possibly damaging	0.46
R3000:Ripor3	UTSW	2	167991180	missense	probably damaging	1.00
R3730:Ripor3	UTSW	2	167992819	missense	probably damaging	1.00
R3731:Ripor3	UTSW	2	167992819	missense	probably damaging	1.00
R4084:Ripor3	UTSW	2	167984466	missense	possibly damaging	0.55
R4796:Ripor3	UTSW	2	167981340	missense	probably damaging	0.97
R4854:Ripor3	UTSW	2	167992813	missense	probably benign	0.05
R4934:Ripor3	UTSW	2	167982816	missense	probably benign
R4968:Ripor3	UTSW	2	167985117	missense	probably benign	0.41
R5662:Ripor3	UTSW	2	167993556	missense	probably benign	0.01
R5739:Ripor3	UTSW	2	167981283	missense	probably damaging	1.00
R5888:Ripor3	UTSW	2	167997287	missense	probably damaging	1.00
R6844:Ripor3	UTSW	2	167993333	splice site	probably null
R6969:Ripor3	UTSW	2	167985737	missense	probably benign	0.01
R6994:Ripor3	UTSW	2	167997266	missense	probably damaging	0.99
R7609:Ripor3	UTSW	2	167984570	missense	possibly damaging	0.86
R7818:Ripor3	UTSW	2	167989426	missense	probably benign	0.09
R8329:Ripor3	UTSW	2	167983199	missense	possibly damaging	0.89
R9120:Ripor3	UTSW	2	167980915	missense	possibly damaging	0.79
R9130:Ripor3	UTSW	2	167981347	nonsense	probably null
R9408:Ripor3	UTSW	2	167989318	missense	probably benign	0.09
R9550:Ripor3	UTSW	2	167980887	missense	probably benign	0.23
R9660:Ripor3	UTSW	2	167989726	missense	probably damaging	0.97

Posted On

2015-04-16