Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02715:Aig1'

304732

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Aig1

Ensembl Gene

ENSMUSG00000019806

Gene Name

androgen-induced 1

Synonyms

1500031O19Rik, CGI-103

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

IGL02715

Quality Score

Status

Chromosome

Chromosomal Location

13522798-13744724 bp(-) (GRCm39)

Type of Mutation

critical splice donor site (2 bp from exon)

DNA Base Change (assembly)

A to G at 13744360 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000125366 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000019942] [ENSMUST00000105534] [ENSMUST00000162610]

AlphaFold

Q9D8B1

Predicted Effect

probably null
Transcript: ENSMUST00000019942

SMART Domains

Protein: ENSMUSP00000019942
Gene: ENSMUSG00000019806

Domain	Start	End	E-Value	Type
Pfam:Far-17a_AIG1	12	219	5.6e-77	PFAM

Predicted Effect

probably null
Transcript: ENSMUST00000105534

SMART Domains

Protein: ENSMUSP00000101174
Gene: ENSMUSG00000019806

Domain	Start	End	E-Value	Type
Pfam:Far-17a_AIG1	12	178	3.4e-59	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000161729

Predicted Effect

probably null
Transcript: ENSMUST00000162610

SMART Domains

Protein: ENSMUSP00000125366
Gene: ENSMUSG00000019806

Domain	Start	End	E-Value	Type
Pfam:Far-17a_AIG1	12	219	5.4e-74	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000162869

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000220029

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 45 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4933427D14Rik	T	C	11: 72,089,714 (GRCm39)	I57V	probably damaging	Het
Abce1	T	A	8: 80,416,990 (GRCm39)	E340D	probably damaging	Het
Agbl2	C	T	2: 90,636,212 (GRCm39)	R583W	probably damaging	Het
Atpsckmt	A	G	15: 31,606,149 (GRCm39)	T36A	probably benign	Het
Brd3	C	A	2: 27,344,495 (GRCm39)	A412S	possibly damaging	Het
C3	A	G	17: 57,511,158 (GRCm39)		probably benign	Het
Ccdc127	A	G	13: 74,504,893 (GRCm39)	E147G	probably benign	Het
Chrna4	A	G	2: 180,671,374 (GRCm39)		probably benign	Het
Cnn2	T	C	10: 79,829,323 (GRCm39)	L151P	probably damaging	Het
Col11a1	G	T	3: 113,923,058 (GRCm39)	M7I	probably benign	Het
Cstdc4	T	C	16: 36,008,315 (GRCm39)	I67T	possibly damaging	Het
Fastkd1	A	G	2: 69,542,469 (GRCm39)		probably null	Het
Fcho2	A	G	13: 98,932,843 (GRCm39)	M53T	probably damaging	Het
Fmnl2	T	C	2: 52,962,222 (GRCm39)	Y236H	possibly damaging	Het
G6bos	A	G	17: 35,284,537 (GRCm39)		probably null	Het
Gramd1a	C	T	7: 30,835,279 (GRCm39)	G436D	probably damaging	Het
Hivep2	A	G	10: 14,007,131 (GRCm39)	Y1243C	probably benign	Het
Lrit2	A	G	14: 36,794,505 (GRCm39)	D523G	probably benign	Het
Lrrc2	A	C	9: 110,799,182 (GRCm39)	D177A	probably damaging	Het
Lyst	T	A	13: 13,848,905 (GRCm39)		probably null	Het
Mrgpra6	A	T	7: 46,838,396 (GRCm39)		probably benign	Het
Myh6	T	C	14: 55,184,365 (GRCm39)		probably benign	Het
Myzap	C	A	9: 71,422,397 (GRCm39)	E392*	probably null	Het
Ndst3	G	A	3: 123,340,410 (GRCm39)		probably benign	Het
Nlrc5	C	A	8: 95,201,296 (GRCm39)	P130H	probably damaging	Het
Obscn	T	C	11: 58,971,137 (GRCm39)	T2526A	probably benign	Het
Or1e26	T	A	11: 73,479,947 (GRCm39)	I206F	probably benign	Het
Pcnt	C	A	10: 76,204,556 (GRCm39)		probably benign	Het
Pfpl	T	A	19: 12,407,145 (GRCm39)	C465*	probably null	Het
Pkd1l3	T	A	8: 110,353,458 (GRCm39)	C680S	probably damaging	Het
Ppp1r10	G	T	17: 36,241,604 (GRCm39)	G793V	unknown	Het
Prss27	A	T	17: 24,263,953 (GRCm39)	D213V	possibly damaging	Het
Sh2d5	T	C	4: 137,984,018 (GRCm39)		probably benign	Het
Spata31d1a	T	C	13: 59,851,549 (GRCm39)	D193G	probably benign	Het
Sptan1	T	C	2: 29,868,588 (GRCm39)	V66A	probably benign	Het
Synpr	T	C	14: 13,608,618 (GRCm38)	S133P	probably damaging	Het
Tagln3	T	C	16: 45,544,588 (GRCm39)	N28D	probably benign	Het
Tfrc	A	G	16: 32,443,189 (GRCm39)	T494A	probably benign	Het
Tmem38a	T	C	8: 73,333,512 (GRCm39)	I77T	possibly damaging	Het
Tmem42	C	A	9: 122,851,295 (GRCm39)	T86N	probably damaging	Het
Ttc8	T	A	12: 98,910,179 (GRCm39)		probably benign	Het
Tub	G	A	7: 108,628,517 (GRCm39)	V342I	probably benign	Het
Vmn2r103	A	T	17: 20,014,218 (GRCm39)	I337F	probably damaging	Het
Xkr7	A	G	2: 152,896,277 (GRCm39)	E377G	probably damaging	Het
Zfp292	C	T	4: 34,819,542 (GRCm39)	G260D	probably damaging	Het

Other mutations in Aig1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL02343:Aig1	APN	10	13,744,418 (GRCm39)	missense	probably damaging	0.99
R0697:Aig1	UTSW	10	13,705,069 (GRCm39)	missense	probably benign	0.01
R1699:Aig1	UTSW	10	13,744,366 (GRCm39)	missense	possibly damaging	0.85
R1761:Aig1	UTSW	10	13,566,328 (GRCm39)	missense	probably damaging	1.00
R3934:Aig1	UTSW	10	13,677,656 (GRCm39)	missense	probably damaging	1.00
R4397:Aig1	UTSW	10	13,528,726 (GRCm39)	missense	probably benign	0.00
R4736:Aig1	UTSW	10	13,677,674 (GRCm39)	missense	probably damaging	0.97
R4767:Aig1	UTSW	10	13,677,602 (GRCm39)	missense	probably damaging	1.00
R5081:Aig1	UTSW	10	13,677,644 (GRCm39)	missense	probably benign	0.01
R5907:Aig1	UTSW	10	13,677,528 (GRCm39)	intron	probably benign
R7944:Aig1	UTSW	10	13,744,417 (GRCm39)	missense	probably damaging	1.00
R9105:Aig1	UTSW	10	13,529,339 (GRCm39)	missense	probably benign	0.10
R9270:Aig1	UTSW	10	13,529,505 (GRCm39)	splice site	probably null
R9381:Aig1	UTSW	10	13,523,417 (GRCm39)	missense	probably benign	0.39
R9778:Aig1	UTSW	10	13,528,757 (GRCm39)	critical splice acceptor site	probably null
X0018:Aig1	UTSW	10	13,566,268 (GRCm39)	nonsense	probably null

Posted On

2015-04-16