Incidental Mutation 'IGL02716:Slc2a7'
ID304798
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Slc2a7
Ensembl Gene ENSMUSG00000062064
Gene Namesolute carrier family 2 (facilitated glucose transporter), member 7
SynonymsOTTMUSG00000010396
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.078) question?
Stock #IGL02716
Quality Score
Status
Chromosome4
Chromosomal Location150148972-150168482 bp(+) (GRCm38)
Type of Mutationsplice site
DNA Base Change (assembly) A to G at 150160010 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000059106 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000059893]
Predicted Effect probably benign
Transcript: ENSMUST00000059893
SMART Domains Protein: ENSMUSP00000059106
Gene: ENSMUSG00000062064

DomainStartEndE-ValueType
Pfam:MFS_1 22 319 2e-15 PFAM
Pfam:Sugar_tr 26 494 7.6e-120 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000133379
Coding Region Coverage
Validation Efficiency
MGI Phenotype FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] SLC2A7 belongs to a family of transporters that catalyze the uptake of sugars through facilitated diffusion (Li et al., 2004). This family of transporters shows conservation of 12 transmembrane helices as well as functionally significant amino acid residues (Joost and Thorens, 2001 [PubMed 11780753]).[supplied by OMIM, Mar 2008]
Allele List at MGI
Other mutations in this stock
Total: 58 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Acsl6 T C 11: 54,327,276 S212P probably benign Het
Ago2 C T 15: 73,111,727 R711Q possibly damaging Het
Akp3 A C 1: 87,125,479 D91A probably damaging Het
Arhgap12 T A 18: 6,111,857 Q169L possibly damaging Het
Aspm A G 1: 139,479,687 Y2104C probably damaging Het
Baz2b G A 2: 59,962,524 S420L possibly damaging Het
Cenpo T C 12: 4,215,390 N210S possibly damaging Het
Chadl T C 15: 81,695,915 N40D probably damaging Het
Crebbp T C 16: 4,114,878 E586G probably benign Het
Cts7 T A 13: 61,356,608 Q47L probably benign Het
Cyp2c40 C A 19: 39,807,536 D133Y possibly damaging Het
Dnah3 A T 7: 119,937,023 M3679K probably damaging Het
Dym T C 18: 75,286,683 Y642H probably damaging Het
Efr3b T C 12: 3,984,627 D65G probably damaging Het
Elmo1 T A 13: 20,449,502 F445I probably damaging Het
Epdr1 C T 13: 19,594,570 V119M probably benign Het
Epha4 G T 1: 77,380,965 R799S probably damaging Het
Esyt3 A T 9: 99,317,224 V778E probably damaging Het
F10 A T 8: 13,048,177 K127* probably null Het
Fcgbp G A 7: 28,101,434 E1302K probably damaging Het
Fer1l4 A G 2: 156,029,715 F1382L probably damaging Het
Fhad1 T C 4: 141,918,331 I318V possibly damaging Het
Fscn2 A T 11: 120,366,724 T304S probably benign Het
Gab1 A T 8: 80,769,694 L659Q probably damaging Het
Gm4845 A C 1: 141,256,838 noncoding transcript Het
Gm572 A G 4: 148,654,870 M52V probably benign Het
Hmgcr T C 13: 96,660,012 probably null Het
Kcnk5 T C 14: 20,181,428 T9A probably damaging Het
Krt87 A C 15: 101,434,604 F243V possibly damaging Het
Mast1 G T 8: 84,935,723 P52Q probably damaging Het
Mcf2l A T 8: 12,997,277 Q211L probably benign Het
Mtus2 C A 5: 148,236,310 P968T probably benign Het
Mylk2 T C 2: 152,922,153 *614R probably null Het
Myo15b A T 11: 115,883,709 E2049V probably benign Het
Myo6 A T 9: 80,269,694 H581L probably damaging Het
Numb A T 12: 83,801,208 S241T possibly damaging Het
Olfr1265 G T 2: 90,037,794 V292L probably benign Het
Olfr1283 A T 2: 111,368,781 I50F probably benign Het
Olfr338 A G 2: 36,377,343 D189G possibly damaging Het
Phldb2 A G 16: 45,801,590 S676P probably damaging Het
Rttn G A 18: 89,048,417 E1196K possibly damaging Het
Skiv2l2 T G 13: 112,883,146 D810A probably benign Het
Slc13a3 G A 2: 165,406,715 P548S unknown Het
Slc37a1 T C 17: 31,328,161 S261P possibly damaging Het
Spryd3 T A 15: 102,133,461 Y42F possibly damaging Het
Srrm3 A G 5: 135,854,433 probably null Het
Stambp G A 6: 83,556,390 T297I probably damaging Het
Sypl T A 12: 32,967,669 Y129N probably damaging Het
Syt14 G A 1: 192,980,535 P368S possibly damaging Het
Tas2r122 T C 6: 132,711,264 D222G probably damaging Het
Tead2 C A 7: 45,232,296 Y79* probably null Het
Tmem251 A G 12: 102,744,829 T104A probably benign Het
Uso1 T C 5: 92,173,935 V229A probably damaging Het
Vmn1r238 A G 18: 3,123,124 S97P probably damaging Het
Vmn2r82 T A 10: 79,377,844 V88D probably benign Het
Vps29 A G 5: 122,362,066 T85A probably benign Het
Wdr90 T A 17: 25,857,220 S500C probably damaging Het
Zfp958 G A 8: 4,625,967 probably null Het
Other mutations in Slc2a7
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01302:Slc2a7 APN 4 150157564 missense probably damaging 1.00
IGL01990:Slc2a7 APN 4 150154684 missense possibly damaging 0.89
IGL02480:Slc2a7 APN 4 150160112 missense possibly damaging 0.93
IGL02607:Slc2a7 APN 4 150154705 missense probably benign
IGL02861:Slc2a7 APN 4 150168379 missense probably benign 0.16
IGL03343:Slc2a7 APN 4 150168340 missense probably damaging 1.00
R0116:Slc2a7 UTSW 4 150168264 missense probably benign 0.31
R0302:Slc2a7 UTSW 4 150149521 missense probably damaging 0.99
R0309:Slc2a7 UTSW 4 150158071 splice site probably benign
R0367:Slc2a7 UTSW 4 150166366 missense probably benign 0.03
R1485:Slc2a7 UTSW 4 150166396 missense probably damaging 1.00
R1542:Slc2a7 UTSW 4 150168471 missense probably damaging 1.00
R1544:Slc2a7 UTSW 4 150154686 missense probably damaging 1.00
R3973:Slc2a7 UTSW 4 150158210 splice site probably null
R4399:Slc2a7 UTSW 4 150158550 missense probably damaging 1.00
R4467:Slc2a7 UTSW 4 150163274 missense possibly damaging 0.95
R4712:Slc2a7 UTSW 4 150168469 missense probably benign 0.00
R5066:Slc2a7 UTSW 4 150160116 missense probably damaging 1.00
R5510:Slc2a7 UTSW 4 150160094 missense probably benign 0.00
R5995:Slc2a7 UTSW 4 150168340 missense probably damaging 1.00
R6017:Slc2a7 UTSW 4 150165172 missense probably damaging 0.99
R6062:Slc2a7 UTSW 4 150168427 missense probably benign
R6185:Slc2a7 UTSW 4 150148993 missense probably benign 0.00
R6730:Slc2a7 UTSW 4 150158148 missense probably damaging 1.00
R7753:Slc2a7 UTSW 4 150154684 missense possibly damaging 0.89
R8145:Slc2a7 UTSW 4 150168361 missense probably damaging 1.00
R8203:Slc2a7 UTSW 4 150158558 nonsense probably null
R8512:Slc2a7 UTSW 4 150163295 missense probably benign 0.23
Posted On2015-04-16