Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02726:Tex56'

305200

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Tex56

Ensembl Gene

ENSMUSG00000021415

Gene Name

testis expressed 56

Synonyms

4933417A18Rik

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.063) question?

Stock #

IGL02726

Quality Score

Status

Chromosome

Chromosomal Location

35108392-35139858 bp(+) (GRCm39)

Type of Mutation

intron

DNA Base Change (assembly)

A to G at 35136943 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000132701 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000021853] [ENSMUST00000160279] [ENSMUST00000160905] [ENSMUST00000164155]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000021853

SMART Domains

Protein: ENSMUSP00000021853
Gene: ENSMUSG00000021416

Domain	Start	End	E-Value	Type
Pfam:ACBP	1	42	3.4e-10	PFAM
Pfam:ECH_1	67	314	4.7e-41	PFAM
Pfam:ECH_2	72	316	1e-21	PFAM

Predicted Effect

unknown
Transcript: ENSMUST00000160279
AA Change: N227S

SMART Domains

Protein: ENSMUSP00000125324
Gene: ENSMUSG00000021415
AA Change: N227S

Domain	Start	End	E-Value	Type
Pfam:DUF4523	34	199	1.1e-89	PFAM

Predicted Effect

unknown
Transcript: ENSMUST00000160905
AA Change: N227S

SMART Domains

Protein: ENSMUSP00000125206
Gene: ENSMUSG00000021415
AA Change: N227S

Domain	Start	End	E-Value	Type
Pfam:DUF4523	34	199	9.5e-102	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000164155

SMART Domains

Protein: ENSMUSP00000132701
Gene: ENSMUSG00000021416

Domain	Start	End	E-Value	Type
Pfam:ACBP	1	45	4.4e-10	PFAM
Pfam:ECH	65	260	5.4e-36	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 44 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Anapc1	A	T	2: 128,501,705 (GRCm39)	M779K	probably benign	Het
Art1	G	A	7: 101,759,955 (GRCm39)	V85M	probably damaging	Het
Atad2b	G	T	12: 5,024,003 (GRCm39)	E43*	probably null	Het
Clec4a4	A	T	6: 122,967,338 (GRCm39)	I5F	probably damaging	Het
Cr1l	A	T	1: 194,812,188 (GRCm39)	I45N	probably damaging	Het
Dmbt1	T	A	7: 130,676,140 (GRCm39)		probably benign	Het
Dnajb3	A	T	1: 88,133,372 (GRCm39)	V10E	probably damaging	Het
Dnajc22	A	T	15: 98,998,881 (GRCm39)	H22L	probably damaging	Het
Dnal4	A	G	15: 79,647,745 (GRCm39)	V40A	probably damaging	Het
Dsg1b	G	A	18: 20,532,542 (GRCm39)	V529I	probably benign	Het
Elp1	T	A	4: 56,767,878 (GRCm39)		probably null	Het
Fam131c	T	A	4: 141,110,113 (GRCm39)	D170E	probably benign	Het
Got1	G	A	19: 43,488,851 (GRCm39)		probably null	Het
Herc1	T	A	9: 66,349,270 (GRCm39)	V2043E	probably benign	Het
Hmcn1	A	T	1: 150,532,445 (GRCm39)	Y3147*	probably null	Het
Ifi44	T	C	3: 151,455,233 (GRCm39)		probably benign	Het
Il1b	A	T	2: 129,209,242 (GRCm39)	D129E	probably damaging	Het
Ino80	A	T	2: 119,272,964 (GRCm39)	I504N	probably damaging	Het
Itpr2	A	G	6: 146,277,419 (GRCm39)	I655T	probably benign	Het
Kcnk4	A	G	19: 6,904,457 (GRCm39)		probably null	Het
Mrgprb2	T	A	7: 48,202,618 (GRCm39)	R36W	probably damaging	Het
Mslnl	T	C	17: 25,963,077 (GRCm39)		probably null	Het
Or10ak14	T	A	4: 118,610,961 (GRCm39)	Y260F	probably benign	Het
Or1e33	T	C	11: 73,738,691 (GRCm39)	S87G	probably benign	Het
Or2ag1b	A	C	7: 106,288,577 (GRCm39)	Y120*	probably null	Het
Or8k16	G	T	2: 85,520,554 (GRCm39)	L260F	possibly damaging	Het
Pcnx4	G	T	12: 72,620,986 (GRCm39)	M935I	probably benign	Het
Pdgfra	C	T	5: 75,355,618 (GRCm39)	Q1043*	probably null	Het
Pf4	T	C	5: 90,920,523 (GRCm39)	V28A	probably benign	Het
Piezo1	A	G	8: 123,213,894 (GRCm39)	L1689P	probably damaging	Het
Ppa2	A	G	3: 133,076,222 (GRCm39)	S284G	possibly damaging	Het
Pramel22	G	T	4: 143,381,955 (GRCm39)	P247H	probably damaging	Het
Psd2	T	C	18: 36,120,355 (GRCm39)		probably null	Het
Rbm25	G	T	12: 83,719,626 (GRCm39)	G549W	probably damaging	Het
Ryr2	T	C	13: 11,753,206 (GRCm39)	D1705G	probably damaging	Het
Shf	A	T	2: 122,189,969 (GRCm39)	D96E	probably damaging	Het
Slc1a1	G	A	19: 28,889,169 (GRCm39)	V481M	probably benign	Het
Slc4a9	T	C	18: 36,672,670 (GRCm39)	V807A	probably benign	Het
Syne2	T	A	12: 76,062,356 (GRCm39)	I4226N	probably damaging	Het
Tkfc	A	T	19: 10,573,576 (GRCm39)	V254E	possibly damaging	Het
Ubr2	A	C	17: 47,283,847 (GRCm39)	Y601D	probably damaging	Het
Ubr5	A	C	15: 38,000,806 (GRCm39)		probably benign	Het
Vmn1r27	A	T	6: 58,192,854 (GRCm39)	I50K	possibly damaging	Het
Wdr55	A	G	18: 36,896,435 (GRCm39)	E375G	probably benign	Het

Other mutations in Tex56

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01992:Tex56	APN	13	35,108,516 (GRCm39)	splice site	probably null
IGL03241:Tex56	APN	13	35,128,313 (GRCm39)	missense	probably damaging	0.98
R0324:Tex56	UTSW	13	35,108,596 (GRCm39)	missense	probably benign
R0394:Tex56	UTSW	13	35,116,636 (GRCm39)	splice site	probably benign
R0409:Tex56	UTSW	13	35,108,532 (GRCm39)	missense	probably benign	0.08
R1639:Tex56	UTSW	13	35,128,233 (GRCm39)	missense	possibly damaging	0.93
R1861:Tex56	UTSW	13	35,116,490 (GRCm39)	missense	possibly damaging	0.80
R2054:Tex56	UTSW	13	35,108,574 (GRCm39)	missense	probably damaging	0.99
R4625:Tex56	UTSW	13	35,116,448 (GRCm39)	missense	probably damaging	1.00
R4932:Tex56	UTSW	13	35,116,613 (GRCm39)	missense	possibly damaging	0.95
R5875:Tex56	UTSW	13	35,116,429 (GRCm39)	missense	probably damaging	0.99
R7837:Tex56	UTSW	13	35,128,359 (GRCm39)	missense	possibly damaging	0.85
R8836:Tex56	UTSW	13	35,116,526 (GRCm39)	missense	probably damaging	0.99
R9266:Tex56	UTSW	13	35,116,569 (GRCm39)	missense	possibly damaging	0.95

Posted On

2015-04-16