Incidental Mutation 'IGL02726:Ifi44'
| ID |
305235 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Ifi44
|
| Ensembl Gene |
ENSMUSG00000028037 |
| Gene Name |
interferon-induced protein 44 |
| Synonyms |
A430056A10Rik, p44, MTAP44 |
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
IGL02726
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
3 |
| Chromosomal Location |
151436559-151455580 bp(-) (GRCm39) |
| Type of Mutation |
start gained |
| DNA Base Change (assembly) |
T to C
at 151455233 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000029671
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000029671]
|
| AlphaFold |
Q8BV66 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000029671
|
| SMART Domains |
Protein: ENSMUSP00000029671
Gene: ENSMUSG00000028037
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:TLD
|
26 |
147 |
2.8e-7 |
PFAM |
|
low complexity region
|
193 |
208 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000127733
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000133888
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000149919
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 44 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Anapc1 |
A |
T |
2: 128,501,705 (GRCm39) |
M779K |
probably benign |
Het |
| Art1 |
G |
A |
7: 101,759,955 (GRCm39) |
V85M |
probably damaging |
Het |
| Atad2b |
G |
T |
12: 5,024,003 (GRCm39) |
E43* |
probably null |
Het |
| Clec4a4 |
A |
T |
6: 122,967,338 (GRCm39) |
I5F |
probably damaging |
Het |
| Cr1l |
A |
T |
1: 194,812,188 (GRCm39) |
I45N |
probably damaging |
Het |
| Dmbt1 |
T |
A |
7: 130,676,140 (GRCm39) |
|
probably benign |
Het |
| Dnajb3 |
A |
T |
1: 88,133,372 (GRCm39) |
V10E |
probably damaging |
Het |
| Dnajc22 |
A |
T |
15: 98,998,881 (GRCm39) |
H22L |
probably damaging |
Het |
| Dnal4 |
A |
G |
15: 79,647,745 (GRCm39) |
V40A |
probably damaging |
Het |
| Dsg1b |
G |
A |
18: 20,532,542 (GRCm39) |
V529I |
probably benign |
Het |
| Elp1 |
T |
A |
4: 56,767,878 (GRCm39) |
|
probably null |
Het |
| Fam131c |
T |
A |
4: 141,110,113 (GRCm39) |
D170E |
probably benign |
Het |
| Got1 |
G |
A |
19: 43,488,851 (GRCm39) |
|
probably null |
Het |
| Herc1 |
T |
A |
9: 66,349,270 (GRCm39) |
V2043E |
probably benign |
Het |
| Hmcn1 |
A |
T |
1: 150,532,445 (GRCm39) |
Y3147* |
probably null |
Het |
| Il1b |
A |
T |
2: 129,209,242 (GRCm39) |
D129E |
probably damaging |
Het |
| Ino80 |
A |
T |
2: 119,272,964 (GRCm39) |
I504N |
probably damaging |
Het |
| Itpr2 |
A |
G |
6: 146,277,419 (GRCm39) |
I655T |
probably benign |
Het |
| Kcnk4 |
A |
G |
19: 6,904,457 (GRCm39) |
|
probably null |
Het |
| Mrgprb2 |
T |
A |
7: 48,202,618 (GRCm39) |
R36W |
probably damaging |
Het |
| Mslnl |
T |
C |
17: 25,963,077 (GRCm39) |
|
probably null |
Het |
| Or10ak14 |
T |
A |
4: 118,610,961 (GRCm39) |
Y260F |
probably benign |
Het |
| Or1e33 |
T |
C |
11: 73,738,691 (GRCm39) |
S87G |
probably benign |
Het |
| Or2ag1b |
A |
C |
7: 106,288,577 (GRCm39) |
Y120* |
probably null |
Het |
| Or8k16 |
G |
T |
2: 85,520,554 (GRCm39) |
L260F |
possibly damaging |
Het |
| Pcnx4 |
G |
T |
12: 72,620,986 (GRCm39) |
M935I |
probably benign |
Het |
| Pdgfra |
C |
T |
5: 75,355,618 (GRCm39) |
Q1043* |
probably null |
Het |
| Pf4 |
T |
C |
5: 90,920,523 (GRCm39) |
V28A |
probably benign |
Het |
| Piezo1 |
A |
G |
8: 123,213,894 (GRCm39) |
L1689P |
probably damaging |
Het |
| Ppa2 |
A |
G |
3: 133,076,222 (GRCm39) |
S284G |
possibly damaging |
Het |
| Pramel22 |
G |
T |
4: 143,381,955 (GRCm39) |
P247H |
probably damaging |
Het |
| Psd2 |
T |
C |
18: 36,120,355 (GRCm39) |
|
probably null |
Het |
| Rbm25 |
G |
T |
12: 83,719,626 (GRCm39) |
G549W |
probably damaging |
Het |
| Ryr2 |
T |
C |
13: 11,753,206 (GRCm39) |
D1705G |
probably damaging |
Het |
| Shf |
A |
T |
2: 122,189,969 (GRCm39) |
D96E |
probably damaging |
Het |
| Slc1a1 |
G |
A |
19: 28,889,169 (GRCm39) |
V481M |
probably benign |
Het |
| Slc4a9 |
T |
C |
18: 36,672,670 (GRCm39) |
V807A |
probably benign |
Het |
| Syne2 |
T |
A |
12: 76,062,356 (GRCm39) |
I4226N |
probably damaging |
Het |
| Tex56 |
A |
G |
13: 35,136,943 (GRCm39) |
|
probably benign |
Het |
| Tkfc |
A |
T |
19: 10,573,576 (GRCm39) |
V254E |
possibly damaging |
Het |
| Ubr2 |
A |
C |
17: 47,283,847 (GRCm39) |
Y601D |
probably damaging |
Het |
| Ubr5 |
A |
C |
15: 38,000,806 (GRCm39) |
|
probably benign |
Het |
| Vmn1r27 |
A |
T |
6: 58,192,854 (GRCm39) |
I50K |
possibly damaging |
Het |
| Wdr55 |
A |
G |
18: 36,896,435 (GRCm39) |
E375G |
probably benign |
Het |
|
| Other mutations in Ifi44 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00858:Ifi44
|
APN |
3 |
151,455,217 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL01477:Ifi44
|
APN |
3 |
151,451,635 (GRCm39) |
splice site |
probably benign |
|
|
IGL01571:Ifi44
|
APN |
3 |
151,451,174 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL02165:Ifi44
|
APN |
3 |
151,455,067 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02238:Ifi44
|
APN |
3 |
151,438,019 (GRCm39) |
makesense |
probably null |
|
|
IGL02609:Ifi44
|
APN |
3 |
151,438,134 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02650:Ifi44
|
APN |
3 |
151,451,492 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02977:Ifi44
|
APN |
3 |
151,445,016 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0201:Ifi44
|
UTSW |
3 |
151,451,273 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0454:Ifi44
|
UTSW |
3 |
151,451,134 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R0763:Ifi44
|
UTSW |
3 |
151,455,135 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1640:Ifi44
|
UTSW |
3 |
151,438,171 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1747:Ifi44
|
UTSW |
3 |
151,454,922 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2278:Ifi44
|
UTSW |
3 |
151,438,025 (GRCm39) |
missense |
probably benign |
|
|
R3816:Ifi44
|
UTSW |
3 |
151,454,894 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4075:Ifi44
|
UTSW |
3 |
151,451,613 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4084:Ifi44
|
UTSW |
3 |
151,451,126 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4782:Ifi44
|
UTSW |
3 |
151,451,229 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5071:Ifi44
|
UTSW |
3 |
151,455,269 (GRCm39) |
start gained |
probably benign |
|
|
R5074:Ifi44
|
UTSW |
3 |
151,455,269 (GRCm39) |
start gained |
probably benign |
|
|
R6030:Ifi44
|
UTSW |
3 |
151,455,195 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6030:Ifi44
|
UTSW |
3 |
151,455,195 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6128:Ifi44
|
UTSW |
3 |
151,454,823 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6192:Ifi44
|
UTSW |
3 |
151,451,276 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R6434:Ifi44
|
UTSW |
3 |
151,454,826 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6536:Ifi44
|
UTSW |
3 |
151,438,126 (GRCm39) |
missense |
probably benign |
0.03 |
|
R6902:Ifi44
|
UTSW |
3 |
151,451,536 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R6946:Ifi44
|
UTSW |
3 |
151,451,536 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R7346:Ifi44
|
UTSW |
3 |
151,438,094 (GRCm39) |
missense |
probably benign |
|
|
R7608:Ifi44
|
UTSW |
3 |
151,438,045 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7704:Ifi44
|
UTSW |
3 |
151,438,061 (GRCm39) |
missense |
probably benign |
0.44 |
|
R7971:Ifi44
|
UTSW |
3 |
151,454,857 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R8255:Ifi44
|
UTSW |
3 |
151,451,619 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8428:Ifi44
|
UTSW |
3 |
151,444,978 (GRCm39) |
nonsense |
probably null |
|
|
R8940:Ifi44
|
UTSW |
3 |
151,454,946 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9087:Ifi44
|
UTSW |
3 |
151,451,517 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9259:Ifi44
|
UTSW |
3 |
151,454,875 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R9436:Ifi44
|
UTSW |
3 |
151,454,886 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9516:Ifi44
|
UTSW |
3 |
151,438,108 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9619:Ifi44
|
UTSW |
3 |
151,451,509 (GRCm39) |
missense |
probably damaging |
0.97 |
|
Z1176:Ifi44
|
UTSW |
3 |
151,438,090 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Ifi44
|
UTSW |
3 |
151,455,075 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Posted On |
2015-04-16 |
Incidental Mutation