Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02736:Antxrl'

305682

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Antxrl

Ensembl Gene

ENSMUSG00000047441

Gene Name

anthrax toxin receptor-like

Synonyms

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

IGL02736

Quality Score

Status

Chromosome

Chromosomal Location

34052707-34076405 bp(+) (GRCm38)

Type of Mutation

unclassified

DNA Base Change (assembly)

A to G at 34056618 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000153806 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000058725] [ENSMUST00000178958] [ENSMUST00000226211] [ENSMUST00000227979]

AlphaFold

Q8BVM2

Predicted Effect

probably benign
Transcript: ENSMUST00000058725

SMART Domains

Protein: ENSMUSP00000052816
Gene: ENSMUSG00000047441

Domain	Start	End	E-Value	Type
signal peptide	1	27	N/A	INTRINSIC
VWA	74	248	2.9e-19	SMART
Pfam:Anth_Ig	249	351	6.7e-41	PFAM
low complexity region	370	381	N/A	INTRINSIC
low complexity region	392	461	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000178958

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000215823

Predicted Effect

probably benign
Transcript: ENSMUST00000226211

Predicted Effect

probably benign
Transcript: ENSMUST00000227979

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 38 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2010300C02Rik	T	C	1: 37,637,873	E76G	probably damaging	Het
9430007A20Rik	G	A	4: 144,528,637	R209K	probably benign	Het
A830018L16Rik	G	A	1: 11,972,051	A416T	probably benign	Het
Akap12	A	G	10: 4,355,637	I816V	probably benign	Het
Atp1a3	G	A	7: 24,980,109	T920I	probably damaging	Het
Cd22	C	T	7: 30,878,045		probably null	Het
Cntn3	T	A	6: 102,203,939	N765I	probably damaging	Het
Crebbp	G	A	16: 4,154,910	P307S	probably benign	Het
Dapk2	T	A	9: 66,268,916	M333K	probably benign	Het
Decr1	T	A	4: 15,930,952	T127S	probably benign	Het
Dnmbp	A	T	19: 43,849,770		probably benign	Het
Erbin	A	G	13: 103,839,395	S664P	probably damaging	Het
Hectd4	G	T	5: 121,342,719	C2941F	possibly damaging	Het
Ighv1-4	A	G	12: 114,487,252	Y79H	probably benign	Het
Matn3	T	A	12: 8,955,422	D277E	possibly damaging	Het
Mgarp	C	A	3: 51,396,445	A36S	possibly damaging	Het
Mycbp2	A	G	14: 103,114,242		probably benign	Het
Nynrin	G	A	14: 55,870,909	A1158T	probably damaging	Het
Olfr427	T	G	1: 174,099,647	I63S	probably damaging	Het
Olfr729	G	A	14: 50,148,424	A150V	probably benign	Het
Palm2	C	A	4: 57,709,721	A222E	probably damaging	Het
Pkd1l2	T	C	8: 117,040,666	D1295G	probably benign	Het
Ppig	A	G	2: 69,736,094	I171M	probably damaging	Het
Ptprs	A	T	17: 56,458,248	V12E	possibly damaging	Het
Rnf123	G	A	9: 108,068,302	R390*	probably null	Het
Rpgrip1l	T	A	8: 91,263,591	Q741L	possibly damaging	Het
Slco6d1	T	C	1: 98,428,311	V157A	possibly damaging	Het
Sox6	A	C	7: 115,580,640	D302E	probably damaging	Het
Spata3	T	C	1: 86,024,435	V136A	probably damaging	Het
St6galnac6	G	A	2: 32,614,971	R129H	probably benign	Het
Tmem184c	A	T	8: 77,597,846	D338E	probably damaging	Het
Tmem67	A	G	4: 12,045,789		probably null	Het
Ttn	A	T	2: 76,878,270		probably benign	Het
Usp16	T	C	16: 87,464,835	V113A	possibly damaging	Het
Utrn	A	G	10: 12,421,640	Y675H	probably damaging	Het
Zc3h4	T	A	7: 16,417,383	Y117*	probably null	Het
Zc3h7b	A	T	15: 81,791,974	M694L	probably benign	Het
Zfp345	A	T	2: 150,474,554	Y45N	probably damaging	Het

Other mutations in Antxrl

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01344:Antxrl	APN	14	34075597	missense	probably benign	0.01
IGL01632:Antxrl	APN	14	34067947	missense	probably damaging	0.99
IGL02379:Antxrl	APN	14	34056535	splice site	probably null
IGL02381:Antxrl	APN	14	34056611	splice site	probably null
R0631:Antxrl	UTSW	14	34058801	critical splice donor site	probably null
R1190:Antxrl	UTSW	14	34069250	missense	probably benign	0.00
R1406:Antxrl	UTSW	14	34073042	missense	possibly damaging	0.53
R1406:Antxrl	UTSW	14	34073042	missense	possibly damaging	0.53
R1454:Antxrl	UTSW	14	34060949	missense	probably damaging	0.99
R1469:Antxrl	UTSW	14	34067431	intron	probably benign
R1638:Antxrl	UTSW	14	34070496	critical splice donor site	probably null
R1996:Antxrl	UTSW	14	34075829	missense	probably benign	0.01
R2174:Antxrl	UTSW	14	34060400	missense	probably damaging	1.00
R2421:Antxrl	UTSW	14	34071689	intron	probably benign
R3850:Antxrl	UTSW	14	34067381	missense	probably benign	0.00
R4178:Antxrl	UTSW	14	34054971	splice site	probably null
R4434:Antxrl	UTSW	14	34071617	intron	probably benign
R4603:Antxrl	UTSW	14	34075835	missense	possibly damaging	0.72
R4769:Antxrl	UTSW	14	34073070	missense	possibly damaging	0.53
R6003:Antxrl	UTSW	14	34075635	missense	possibly damaging	0.72
R6047:Antxrl	UTSW	14	34053476	intron	probably benign
R6228:Antxrl	UTSW	14	34056599	missense	probably damaging	1.00
R6363:Antxrl	UTSW	14	34069287	missense	probably damaging	1.00
R6525:Antxrl	UTSW	14	34060406	missense	probably damaging	1.00
R6800:Antxrl	UTSW	14	34065907	missense	probably damaging	1.00
R6933:Antxrl	UTSW	14	34075771	missense	possibly damaging	0.53
R7086:Antxrl	UTSW	14	34065916	missense	probably benign	0.26
R7257:Antxrl	UTSW	14	34065849	missense	probably benign	0.03
R7315:Antxrl	UTSW	14	34071547	missense	unknown
R7981:Antxrl	UTSW	14	34065881	missense	probably damaging	0.99
R9070:Antxrl	UTSW	14	34071714	nonsense	probably null
R9097:Antxrl	UTSW	14	34071703	missense	probably benign	0.33
X0028:Antxrl	UTSW	14	34053915	critical splice donor site	probably null
Z1088:Antxrl	UTSW	14	34067971	missense	probably damaging	1.00
Z1177:Antxrl	UTSW	14	34067930	frame shift	probably null

Posted On

2015-04-16