Incidental Mutation 'IGL02739:Fam169a'
ID305825
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Fam169a
Ensembl Gene ENSMUSG00000041817
Gene Namefamily with sequence similarity 169, member A
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.088) question?
Stock #IGL02739
Quality Score
Status
Chromosome13
Chromosomal Location97067286-97131013 bp(+) (GRCm38)
Type of Mutationsplice site
DNA Base Change (assembly) A to G at 97094055 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000126209 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000042517] [ENSMUST00000071118] [ENSMUST00000169863]
Predicted Effect probably benign
Transcript: ENSMUST00000042517
SMART Domains Protein: ENSMUSP00000043738
Gene: ENSMUSG00000041817

DomainStartEndE-ValueType
low complexity region 374 386 N/A INTRINSIC
low complexity region 602 619 N/A INTRINSIC
low complexity region 630 642 N/A INTRINSIC
low complexity region 650 663 N/A INTRINSIC
Predicted Effect probably benign
Transcript: ENSMUST00000071118
SMART Domains Protein: ENSMUSP00000132645
Gene: ENSMUSG00000057762

DomainStartEndE-ValueType
Pfam:MARVEL 19 132 2.2e-14 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000169863
SMART Domains Protein: ENSMUSP00000126209
Gene: ENSMUSG00000041817

DomainStartEndE-ValueType
low complexity region 374 386 N/A INTRINSIC
low complexity region 602 619 N/A INTRINSIC
low complexity region 630 642 N/A INTRINSIC
low complexity region 650 663 N/A INTRINSIC
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 40 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Aasdh A T 5: 76,878,517 C887S possibly damaging Het
Adamdec1 C A 14: 68,570,156 E352* probably null Het
Bglap2 A T 3: 88,378,012 probably null Het
Bsn A T 9: 108,112,546 H2002Q probably benign Het
Chtop T A 3: 90,502,250 Q165L possibly damaging Het
Clcn1 A T 6: 42,286,780 probably null Het
Ctsr T C 13: 61,161,844 T184A probably benign Het
Defb36 T C 2: 152,604,519 L11P unknown Het
Dock8 A G 19: 25,188,488 E1912G probably damaging Het
Dpp3 A G 19: 4,923,728 Y106H probably damaging Het
Epas1 A G 17: 86,805,282 T103A probably damaging Het
Epcam A T 17: 87,640,494 T131S probably benign Het
Gh T A 11: 106,301,733 probably benign Het
Kif20a A T 18: 34,628,943 K399* probably null Het
Lrp1b A G 2: 41,498,215 I466T probably damaging Het
Nlk A G 11: 78,574,851 V409A probably benign Het
Nomo1 A G 7: 46,044,307 probably null Het
Nr2c1 T A 10: 94,156,972 M16K probably damaging Het
Nxph2 A T 2: 23,399,900 Q88L probably benign Het
Olfr33 A G 7: 102,714,314 I33T possibly damaging Het
Pkdrej T A 15: 85,819,694 R680S probably benign Het
Pkhd1l1 A T 15: 44,540,950 N2325I probably benign Het
Pnliprp2 T C 19: 58,760,509 probably null Het
Ppp1r42 T A 1: 9,968,853 K347N probably benign Het
Prtg T C 9: 72,851,585 V407A possibly damaging Het
Psmb8 C A 17: 34,200,754 S194* probably null Het
Rnf214 T C 9: 45,869,474 I406V probably benign Het
Rreb1 C T 13: 37,893,821 S3L probably damaging Het
Sdad1 C T 5: 92,290,072 A539T probably benign Het
Sema3a A G 5: 13,451,161 Y57C probably damaging Het
Susd5 A G 9: 114,096,033 E328G possibly damaging Het
Syngr3 T C 17: 24,686,398 T175A probably damaging Het
Tcf20 T A 15: 82,856,080 Q390L probably damaging Het
Tex15 A G 8: 33,581,693 T2423A possibly damaging Het
Tlr1 T C 5: 64,927,126 N36S probably benign Het
Uchl4 C T 9: 64,235,537 T100M probably damaging Het
Uhrf1 A G 17: 56,305,129 K11R probably benign Het
Vps13b T A 15: 35,879,900 D3040E probably damaging Het
Wdr62 A T 7: 30,242,460 Y640* probably null Het
Zkscan17 T G 11: 59,503,526 E83A probably damaging Het
Other mutations in Fam169a
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01325:Fam169a APN 13 97122699 missense probably benign 0.00
IGL01380:Fam169a APN 13 97091951 missense probably damaging 0.97
IGL01761:Fam169a APN 13 97091918 missense possibly damaging 0.92
IGL02628:Fam169a APN 13 97111288 splice site probably benign
IGL03171:Fam169a APN 13 97110014 splice site probably benign
IGL03306:Fam169a APN 13 97106989 missense possibly damaging 0.66
IGL03377:Fam169a APN 13 97091873 missense probably benign 0.04
IGL02980:Fam169a UTSW 13 97113680 critical splice donor site probably null
R0282:Fam169a UTSW 13 97097715 splice site probably benign
R1319:Fam169a UTSW 13 97097562 missense probably damaging 1.00
R1468:Fam169a UTSW 13 97118530 missense probably benign 0.01
R1468:Fam169a UTSW 13 97118530 missense probably benign 0.01
R2037:Fam169a UTSW 13 97107092 missense probably benign 0.37
R2380:Fam169a UTSW 13 97118535 splice site probably benign
R3805:Fam169a UTSW 13 97097684 missense probably benign 0.00
R4434:Fam169a UTSW 13 97126740 missense probably damaging 1.00
R4435:Fam169a UTSW 13 97126740 missense probably damaging 1.00
R4437:Fam169a UTSW 13 97126740 missense probably damaging 1.00
R4590:Fam169a UTSW 13 97097585 missense probably benign 0.02
R4896:Fam169a UTSW 13 97097592 missense probably damaging 1.00
R5004:Fam169a UTSW 13 97097592 missense probably damaging 1.00
R5276:Fam169a UTSW 13 97118496 missense probably benign 0.01
R5370:Fam169a UTSW 13 97106962 missense probably damaging 1.00
R5687:Fam169a UTSW 13 97093618 missense probably damaging 1.00
R6151:Fam169a UTSW 13 97093630 missense probably damaging 1.00
R7711:Fam169a UTSW 13 97126688 nonsense probably null
R8322:Fam169a UTSW 13 97122752 missense probably benign 0.00
R8493:Fam169a UTSW 13 97122859 missense probably benign 0.00
R8698:Fam169a UTSW 13 97107070 missense probably damaging 1.00
R8794:Fam169a UTSW 13 97114120 missense possibly damaging 0.85
Posted On2015-04-16