Incidental Mutation 'IGL00973:Tubb4b-ps1'
ID306627
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Tubb4b-ps1
Ensembl Gene ENSMUSG00000095159
Gene Nametubulin, beta 4B class IVB, pseudogene 1
SynonymsTubb2c-ps1, Tubb2c2, ENSMUSG00000056506
Accession Numbers
Is this an essential gene? Not available question?
Stock #IGL00973
Quality Score
Status
Chromosome5
Chromosomal Location7179365-7180699 bp(+) (GRCm38)
Type of Mutationintron
DNA Base Change (assembly) A to G at 7179408 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000143568 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000200317]
Predicted Effect noncoding transcript
Transcript: ENSMUST00000082917
Predicted Effect noncoding transcript
Transcript: ENSMUST00000179460
SMART Domains Protein: ENSMUSP00000136922
Gene: ENSMUSG00000095159

DomainStartEndE-ValueType
Tubulin 47 243 6.6e-61 SMART
Tubulin_C 245 382 4.17e-49 SMART
low complexity region 427 444 N/A INTRINSIC
Predicted Effect probably benign
Transcript: ENSMUST00000200317
SMART Domains Protein: ENSMUSP00000143568
Gene: ENSMUSG00000092094

DomainStartEndE-ValueType
ZnF_C2H2 56 80 2e-2 SMART
low complexity region 958 970 N/A INTRINSIC
low complexity region 1155 1179 N/A INTRINSIC
low complexity region 1196 1207 N/A INTRINSIC
low complexity region 1215 1234 N/A INTRINSIC
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 31 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Atp10a G T 7: 58,807,470 D906Y probably damaging Het
Cdh18 A G 15: 23,173,796 K32R probably damaging Het
Chtf18 G A 17: 25,722,116 A636V probably benign Het
Clcn6 A G 4: 148,013,788 probably benign Het
Dspp A C 5: 104,176,892 K374Q possibly damaging Het
Dusp27 T C 1: 166,099,458 S862G probably benign Het
Ehmt2 C T 17: 34,910,815 R962C probably damaging Het
Frrs1l T C 4: 56,972,369 K111E probably damaging Het
Galnt5 A G 2: 57,998,939 T184A probably benign Het
Glud1 C T 14: 34,319,942 T169I probably damaging Het
Hinfp T G 9: 44,298,139 D283A probably benign Het
Hmcn2 C T 2: 31,383,821 probably benign Het
Hs6st3 A T 14: 119,869,407 Y409F possibly damaging Het
Ighv15-2 A T 12: 114,564,870 V20D possibly damaging Het
Kif17 A G 4: 138,275,057 T91A probably benign Het
Mical3 T C 6: 120,934,924 probably benign Het
Myo1e C T 9: 70,338,787 T420M probably damaging Het
Olfr876 C A 9: 37,804,782 S290R probably damaging Het
Ovgp1 T A 3: 105,981,277 Y316* probably null Het
Plekha1 T A 7: 130,911,013 V313D probably damaging Het
Polr1e C A 4: 45,031,364 probably benign Het
Prdm15 A T 16: 97,806,167 probably benign Het
Ptpn4 T A 1: 119,741,371 M250L probably benign Het
Rtn1 A T 12: 72,408,511 L14Q probably benign Het
Sec24a T C 11: 51,729,577 probably null Het
Sox7 A G 14: 63,948,187 H224R probably benign Het
Sucla2 T C 14: 73,590,907 I318T possibly damaging Het
Ube2o T A 11: 116,541,205 K940M probably damaging Het
Usp20 A C 2: 31,004,950 N149T probably damaging Het
Utp6 C T 11: 79,955,705 W150* probably null Het
Wdr27 A C 17: 14,913,878 H475Q probably benign Het
Other mutations in Tubb4b-ps1
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01861:Tubb4b-ps1 APN 5 7179374 intron probably benign
IGL01980:Tubb4b-ps1 APN 5 7179843 intron probably benign
IGL02336:Tubb4b-ps1 APN 5 7179952 intron probably benign
IGL03152:Tubb4b-ps1 APN 5 7180001 intron probably benign
IGL03166:Tubb4b-ps1 APN 5 7179965 intron probably benign
IGL03279:Tubb4b-ps1 APN 5 7179630 intron probably benign
Posted On2015-04-16