Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL00233:Vmn1r191'

306832

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn1r191

Ensembl Gene

ENSMUSG00000095916

Gene Name

vomeronasal 1 receptor 191

Synonyms

V1rh15

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.153) question?

Stock #

IGL00233

Quality Score

Status

Chromosome

Chromosomal Location

22362856-22363752 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 22362890 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Aspartic acid to Glycine at position 288 (D288G)

Ref Sequence

ENSEMBL: ENSMUSP00000072206 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000072369]

AlphaFold

Q8K4D0

Predicted Effect

probably damaging
Transcript: ENSMUST00000072369
AA Change: D288G

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000072206
Gene: ENSMUSG00000095916
AA Change: D288G

Domain	Start	End	E-Value	Type
transmembrane domain	12	34	N/A	INTRINSIC
Pfam:V1R	35	291	4.4e-33	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000120067

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 34 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Aimp1	A	T	3: 132,382,904 (GRCm39)		probably benign	Het
Arpc5	A	G	1: 152,644,658 (GRCm39)	I64V	probably benign	Het
C030048H21Rik	G	A	2: 26,146,632 (GRCm39)	R1227W	probably damaging	Het
Cacnb1	T	C	11: 97,913,190 (GRCm39)	E21G	possibly damaging	Het
Catsper3	A	G	13: 55,946,635 (GRCm39)	K111E	possibly damaging	Het
Cda	T	C	4: 138,095,157 (GRCm39)	Y33C	probably damaging	Het
Celsr3	A	T	9: 108,726,124 (GRCm39)	R3118W	probably damaging	Het
Clvs1	G	A	4: 9,281,939 (GRCm39)	G128R	probably damaging	Het
Col9a1	A	G	1: 24,224,306 (GRCm39)	S163G	unknown	Het
Cyp4v3	T	C	8: 45,760,040 (GRCm39)	D64G	probably benign	Het
Dst	C	A	1: 34,290,920 (GRCm39)	L837M	probably damaging	Het
Eif2ak4	T	A	2: 118,294,536 (GRCm39)	I1349N	probably damaging	Het
Elob	C	A	17: 24,043,954 (GRCm39)		probably null	Het
Glipr1	T	A	10: 111,821,555 (GRCm39)	I216L	probably benign	Het
Gm3238	C	T	10: 77,607,126 (GRCm39)		probably benign	Het
Gm43638	C	T	5: 87,608,258 (GRCm39)	R527H	probably damaging	Het
H2-M11	A	G	17: 36,858,445 (GRCm39)	K80E	probably benign	Het
Htt	A	G	5: 35,053,370 (GRCm39)		probably null	Het
Kif26a	A	G	12: 112,124,066 (GRCm39)	S224G	probably damaging	Het
Mgat5b	T	A	11: 116,822,488 (GRCm39)	M74K	probably damaging	Het
Ms4a7	A	T	19: 11,299,724 (GRCm39)	V89D	probably damaging	Het
Nlrx1	G	A	9: 44,175,365 (GRCm39)	T137I	probably benign	Het
Pcdhb12	A	G	18: 37,570,035 (GRCm39)	T394A	probably benign	Het
Pkhd1l1	T	C	15: 44,340,982 (GRCm39)	I151T	probably damaging	Het
Plcl1	T	C	1: 55,445,695 (GRCm39)	V50A	probably benign	Het
Prkd2	T	C	7: 16,599,787 (GRCm39)	F750S	probably damaging	Het
Psmd13	T	C	7: 140,477,534 (GRCm39)	V311A	probably damaging	Het
Rec8	C	T	14: 55,860,972 (GRCm39)	Q334*	probably null	Het
Rfx7	G	A	9: 72,514,972 (GRCm39)	V157I	probably damaging	Het
Sele	G	A	1: 163,879,403 (GRCm39)	C312Y	probably damaging	Het
Sorcs3	A	G	19: 48,736,758 (GRCm39)	T694A	probably benign	Het
Tma16	G	T	8: 66,933,097 (GRCm39)	Q95K	probably benign	Het
Vmn1r231	A	T	17: 21,110,828 (GRCm39)	I29N	possibly damaging	Het
Vmn2r1	T	A	3: 64,012,389 (GRCm39)	L750*	probably null	Het

Other mutations in Vmn1r191

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01645:Vmn1r191	APN	13	22,363,614 (GRCm39)	missense	probably benign	0.03
IGL02224:Vmn1r191	APN	13	22,363,068 (GRCm39)	missense	probably damaging	1.00
IGL02321:Vmn1r191	APN	13	22,363,068 (GRCm39)	nonsense	probably null
IGL02516:Vmn1r191	APN	13	22,363,710 (GRCm39)	missense	probably benign	0.38
IGL02602:Vmn1r191	APN	13	22,363,635 (GRCm39)	missense	probably damaging	1.00
IGL02630:Vmn1r191	APN	13	22,363,431 (GRCm39)	missense	possibly damaging	0.95
IGL03077:Vmn1r191	APN	13	22,363,316 (GRCm39)	missense	probably benign	0.07
IGL03380:Vmn1r191	APN	13	22,363,055 (GRCm39)	missense	probably damaging	0.99
R0571:Vmn1r191	UTSW	13	22,363,217 (GRCm39)	missense	probably damaging	0.96
R0981:Vmn1r191	UTSW	13	22,363,389 (GRCm39)	missense	probably benign	0.00
R1672:Vmn1r191	UTSW	13	22,363,262 (GRCm39)	missense	probably benign	0.01
R1955:Vmn1r191	UTSW	13	22,362,985 (GRCm39)	missense	possibly damaging	0.79
R1969:Vmn1r191	UTSW	13	22,362,952 (GRCm39)	missense	possibly damaging	0.71
R5059:Vmn1r191	UTSW	13	22,363,163 (GRCm39)	missense	probably damaging	1.00
R6484:Vmn1r191	UTSW	13	22,362,918 (GRCm39)	missense	probably benign	0.00
R6736:Vmn1r191	UTSW	13	22,363,720 (GRCm39)	missense	probably benign	0.14
R7063:Vmn1r191	UTSW	13	22,362,864 (GRCm39)	missense	probably benign	0.08
R7475:Vmn1r191	UTSW	13	22,362,942 (GRCm39)	missense	probably benign	0.00
R9699:Vmn1r191	UTSW	13	22,363,355 (GRCm39)	missense	probably benign	0.25

Posted On

2015-04-16