Incidental Mutation 'IGL00233:Vmn1r231'
ID306851
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Vmn1r231
Ensembl Gene ENSMUSG00000050933
Gene Namevomeronasal 1 receptor 231
SynonymsV1re7
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.056) question?
Stock #IGL00233
Quality Score
Status
Chromosome17
Chromosomal Location20889716-20890651 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to T at 20890566 bp
ZygosityHeterozygous
Amino Acid Change Isoleucine to Asparagine at position 29 (I29N)
Ref Sequence ENSEMBL: ENSMUSP00000056228 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000061278]
Predicted Effect possibly damaging
Transcript: ENSMUST00000061278
AA Change: I29N

PolyPhen 2 Score 0.676 (Sensitivity: 0.86; Specificity: 0.92)
SMART Domains Protein: ENSMUSP00000056228
Gene: ENSMUSG00000050933
AA Change: I29N

DomainStartEndE-ValueType
Pfam:TAS2R 6 294 1.6e-13 PFAM
Pfam:V1R 36 297 1.6e-27 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000232004
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 34 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Aimp1 A T 3: 132,677,143 probably benign Het
Arpc5 A G 1: 152,768,907 I64V probably benign Het
C030048H21Rik G A 2: 26,256,620 R1227W probably damaging Het
Cacnb1 T C 11: 98,022,364 E21G possibly damaging Het
Catsper3 A G 13: 55,798,822 K111E possibly damaging Het
Cda T C 4: 138,367,846 Y33C probably damaging Het
Celsr3 A T 9: 108,848,925 R3118W probably damaging Het
Clvs1 G A 4: 9,281,939 G128R probably damaging Het
Col9a1 A G 1: 24,185,225 S163G unknown Het
Cyp4v3 T C 8: 45,307,003 D64G probably benign Het
Dst C A 1: 34,251,839 L837M probably damaging Het
Eif2ak4 T A 2: 118,464,055 I1349N probably damaging Het
Elob C A 17: 23,824,980 probably null Het
Glipr1 T A 10: 111,985,650 I216L probably benign Het
Gm3238 C T 10: 77,771,292 probably benign Het
Gm43638 C T 5: 87,460,399 R527H probably damaging Het
H2-M11 A G 17: 36,547,553 K80E probably benign Het
Htt A G 5: 34,896,026 probably null Het
Kif26a A G 12: 112,157,632 S224G probably damaging Het
Mgat5b T A 11: 116,931,662 M74K probably damaging Het
Ms4a7 A T 19: 11,322,360 V89D probably damaging Het
Nlrx1 G A 9: 44,264,068 T137I probably benign Het
Pcdhb12 A G 18: 37,436,982 T394A probably benign Het
Pkhd1l1 T C 15: 44,477,586 I151T probably damaging Het
Plcl1 T C 1: 55,406,536 V50A probably benign Het
Prkd2 T C 7: 16,865,862 F750S probably damaging Het
Psmd13 T C 7: 140,897,621 V311A probably damaging Het
Rec8 C T 14: 55,623,515 Q334* probably null Het
Rfx7 G A 9: 72,607,690 V157I probably damaging Het
Sele G A 1: 164,051,834 C312Y probably damaging Het
Sorcs3 A G 19: 48,748,319 T694A probably benign Het
Tma16 G T 8: 66,480,445 Q95K probably benign Het
Vmn1r191 T C 13: 22,178,720 D288G probably damaging Het
Vmn2r1 T A 3: 64,104,968 L750* probably null Het
Other mutations in Vmn1r231
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02124:Vmn1r231 APN 17 20890306 missense probably damaging 1.00
IGL02151:Vmn1r231 APN 17 20889735 missense probably benign 0.06
R0066:Vmn1r231 UTSW 17 20889736 missense probably benign 0.27
R0066:Vmn1r231 UTSW 17 20889736 missense probably benign 0.27
R0396:Vmn1r231 UTSW 17 20890399 missense probably damaging 0.98
R0427:Vmn1r231 UTSW 17 20890228 missense probably benign 0.05
R0470:Vmn1r231 UTSW 17 20890003 nonsense probably null
R0848:Vmn1r231 UTSW 17 20890171 missense probably damaging 1.00
R1692:Vmn1r231 UTSW 17 20890609 missense probably benign 0.02
R1987:Vmn1r231 UTSW 17 20889950 missense probably damaging 1.00
R1988:Vmn1r231 UTSW 17 20889950 missense probably damaging 1.00
R2105:Vmn1r231 UTSW 17 20890118 missense possibly damaging 0.66
R4440:Vmn1r231 UTSW 17 20890456 missense possibly damaging 0.48
R4634:Vmn1r231 UTSW 17 20890398 missense possibly damaging 0.46
R4646:Vmn1r231 UTSW 17 20890309 missense probably damaging 1.00
R4678:Vmn1r231 UTSW 17 20890227 missense possibly damaging 0.94
R4696:Vmn1r231 UTSW 17 20890639 missense possibly damaging 0.63
R4938:Vmn1r231 UTSW 17 20890351 missense possibly damaging 0.76
R5544:Vmn1r231 UTSW 17 20890578 missense probably damaging 1.00
R5942:Vmn1r231 UTSW 17 20890155 missense possibly damaging 0.83
R6053:Vmn1r231 UTSW 17 20889819 missense probably damaging 1.00
R6692:Vmn1r231 UTSW 17 20890483 missense possibly damaging 0.46
R6712:Vmn1r231 UTSW 17 20889730 missense possibly damaging 0.54
R7131:Vmn1r231 UTSW 17 20889878 missense possibly damaging 0.87
R7854:Vmn1r231 UTSW 17 20890632 missense probably damaging 0.98
R7937:Vmn1r231 UTSW 17 20890632 missense probably damaging 0.98
R8187:Vmn1r231 UTSW 17 20890631 missense probably benign 0.10
R8238:Vmn1r231 UTSW 17 20890378 missense probably benign 0.08
R8313:Vmn1r231 UTSW 17 20890027 missense probably benign 0.02
RF010:Vmn1r231 UTSW 17 20889993 missense probably damaging 0.99
Posted On2015-04-16