Mutagenetix > Incidental Mutation

Incidental Mutation 'R3879:Gm9894'

308692

Institutional Source

Beutler Lab

Gene Symbol

Gm9894

Ensembl Gene

ENSMUSG00000052909

Gene Name

predicted gene 9894

Synonyms

MMRRC Submission

040793-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.099) question?

Stock #

R3879 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

67912366-67913184 bp(-) (GRCm39)

Type of Mutation

exon

DNA Base Change (assembly)

T to C at 67912916 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Gene Model

predicted gene model for transcript(s):

AlphaFold

no structure available at present

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000171257

SMART Domains

Protein: ENSMUSP00000125787
Gene: ENSMUSG00000052909

Domain	Start	End	E-Value	Type
KRAB	5	65	9.53e-30	SMART
ZnF_C2H2	109	132	7.15e-2	SMART
ZnF_C2H2	138	160	8.34e-3	SMART
ZnF_C2H2	166	188	5.4e1	SMART
ZnF_C2H2	194	216	9.96e-1	SMART
ZnF_C2H2	222	244	1.18e-2	SMART
ZnF_C2H2	278	300	2.57e-3	SMART
ZnF_C2H2	306	328	5.26e1	SMART

Meta Mutation Damage Score

0.0869

Coding Region Coverage

1x: 99.2%
3x: 98.6%
10x: 97.4%
20x: 95.5%

Validation Efficiency

95% (38/40)

Allele List at MGI

Other mutations in this stock

Total: 33 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4933434E20Rik	T	C	3: 89,970,561 (GRCm39)		probably benign	Het
Aass	G	A	6: 23,122,520 (GRCm39)	H68Y	probably damaging	Het
Abcc8	T	A	7: 45,754,051 (GRCm39)	K1588N	possibly damaging	Het
Calcoco1	T	C	15: 102,615,823 (GRCm39)	D601G	probably damaging	Het
Ccdc175	C	A	12: 72,182,792 (GRCm39)	R409I	probably damaging	Het
Ccnl1	A	G	3: 65,856,179 (GRCm39)	V242A	possibly damaging	Het
Clasp2	T	C	9: 113,719,029 (GRCm39)	F705L	probably damaging	Het
Cyp46a1	A	G	12: 108,324,389 (GRCm39)	T389A	probably benign	Het
Eps8	A	G	6: 137,504,360 (GRCm39)		probably benign	Het
Kcnd3	C	T	3: 105,566,082 (GRCm39)	A421V	probably damaging	Het
Nup153	A	T	13: 46,837,436 (GRCm39)	V1262E	probably damaging	Het
Nup210l	A	G	3: 90,092,780 (GRCm39)	T1245A	probably damaging	Het
Or10ad1b	C	T	15: 98,125,085 (GRCm39)	C147Y	probably damaging	Het
Or5b121	A	G	19: 13,507,613 (GRCm39)	Y236C	probably damaging	Het
Pcif1	G	A	2: 164,727,878 (GRCm39)	G189D	probably benign	Het
Pdzd2	A	G	15: 12,375,594 (GRCm39)	S1514P	probably damaging	Het
Pigu	A	T	2: 155,141,063 (GRCm39)	F276I	probably damaging	Het
Pramex1	T	C	X: 134,514,194 (GRCm39)	H365R	probably benign	Het
Psmd9	C	T	5: 123,372,653 (GRCm39)		probably benign	Het
Rasgrp2	A	T	19: 6,463,920 (GRCm39)	Q539H	probably benign	Het
Rgs22	T	G	15: 36,107,051 (GRCm39)	I112L	possibly damaging	Het
Slc26a9	A	T	1: 131,696,969 (GRCm39)	T786S	probably benign	Het
Sned1	A	G	1: 93,192,752 (GRCm39)		probably benign	Het
St7l	G	A	3: 104,833,763 (GRCm39)	V475I	probably damaging	Het
Tnfrsf11a	C	T	1: 105,737,085 (GRCm39)	T64I	probably damaging	Het
Top3a	A	G	11: 60,634,765 (GRCm39)	V713A	possibly damaging	Het
Trim16	G	A	11: 62,731,433 (GRCm39)	G348S	probably damaging	Het
Tshz3	C	T	7: 36,470,962 (GRCm39)	Q984*	probably null	Het
Ttn	A	G	2: 76,566,406 (GRCm39)		probably null	Het
Ubfd1	T	A	7: 121,667,999 (GRCm39)		probably benign	Het
Zfp37	A	T	4: 62,109,572 (GRCm39)	Y497*	probably null	Het
Zfp462	G	A	4: 55,060,095 (GRCm39)	C1207Y	probably damaging	Het
Zfp607b	A	G	7: 27,403,476 (GRCm39)	E644G	possibly damaging	Het

Other mutations in Gm9894

Allele	Source	Chr	Coord	Type	Predicted Effect
IGL00473:Gm9894	APN	13	67,913,236 (GRCm39)	exon	noncoding transcript
IGL02474:Gm9894	APN	13	67,913,213 (GRCm39)	exon	noncoding transcript
R0412:Gm9894	UTSW	13	67,913,145 (GRCm39)	exon	noncoding transcript
R1170:Gm9894	UTSW	13	67,912,820 (GRCm39)	exon	noncoding transcript
R1604:Gm9894	UTSW	13	67,913,008 (GRCm39)	exon	noncoding transcript
R1617:Gm9894	UTSW	13	67,920,845 (GRCm39)	critical splice donor site	noncoding transcript
R1961:Gm9894	UTSW	13	67,912,034 (GRCm39)	exon	noncoding transcript
R4450:Gm9894	UTSW	13	67,913,199 (GRCm39)	exon	noncoding transcript
R4666:Gm9894	UTSW	13	67,913,213 (GRCm39)	exon	noncoding transcript
R6020:Gm9894	UTSW	13	67,911,954 (GRCm39)	exon	noncoding transcript

Predicted Primers

PCR Primer
(F):5'- CTCCAGTATGAGCTATTTTGTGTTC -3'
(R):5'- GGCCTTTGATTGTAACTCACTC -3'

Sequencing Primer
(F):5'- TCCATAAAGGTTACACTTGTAGGG -3'
(R):5'- TCCTACAAGTGTGAAGACTCTGGC -3'

Posted On

2015-04-17