Mutagenetix > Incidental Mutation

Incidental Mutation 'R3904:Alms1'

309099

Institutional Source

Beutler Lab

Gene Symbol

Alms1

Ensembl Gene

ENSMUSG00000063810

Gene Name

ALMS1, centrosome and basal body associated

Synonyms

MMRRC Submission

040812-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R3904 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

85587531-85702753 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 85621678 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Aspartic acid to Glycine at position 1631 (D1631G)

Ref Sequence

ENSEMBL: ENSMUSP00000148796 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000072018] [ENSMUST00000213058]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000072018
AA Change: D1162G

PolyPhen 2 Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)

SMART Domains

Protein: ENSMUSP00000071904
Gene: ENSMUSG00000063810
AA Change: D1162G

Domain	Start	End	E-Value	Type
coiled coil region	10	39	N/A	INTRINSIC
low complexity region	67	80	N/A	INTRINSIC
low complexity region	98	119	N/A	INTRINSIC
Blast:MYSc	127	233	1e-21	BLAST
internal_repeat_3	408	511	2.48e-7	PROSPERO
internal_repeat_2	414	804	2.09e-12	PROSPERO
internal_repeat_1	438	834	4.54e-18	PROSPERO
internal_repeat_3	652	757	2.48e-7	PROSPERO
low complexity region	903	908	N/A	INTRINSIC
internal_repeat_1	916	1385	4.54e-18	PROSPERO
internal_repeat_2	1024	1390	2.09e-12	PROSPERO
low complexity region	1572	1586	N/A	INTRINSIC
low complexity region	2004	2017	N/A	INTRINSIC
low complexity region	2760	2773	N/A	INTRINSIC
low complexity region	2950	2968	N/A	INTRINSIC
low complexity region	3013	3030	N/A	INTRINSIC
Pfam:ALMS_motif	3125	3247	1.8e-42	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000213058
AA Change: D1631G

PolyPhen 2 Score 0.002 (Sensitivity: 0.99; Specificity: 0.30)

Meta Mutation Damage Score

0.0898

Coding Region Coverage

1x: 99.2%
3x: 98.7%
10x: 97.6%
20x: 95.9%

Validation Efficiency

100% (39/39)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a protein containing a large tandem-repeat domain as well as additional low complexity regions. The encoded protein functions in microtubule organization, particularly in the formation and maintanance of cilia. Mutations in this gene cause Alstrom syndrome. There is a pseudogene for this gene located adjacent in the same region of chromosome 2. Alternative splice variants have been described but their full length nature has not been determined. [provided by RefSeq, Apr 2014]
PHENOTYPE: Homozygous null mice display obesity starting after puberty, hypogonadism, hyperinsulinemia, male-specific hyperglycemia, retinal dysfunction, and late-onset hearing loss. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 38 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1110002E22Rik	A	C	3: 138,066,639 (GRCm38)	I530L	probably benign	Het
5930422O12Rik	T	C	8: 33,429,439 (GRCm38)	S96P	probably damaging	Het
Acot4	A	G	12: 84,043,327 (GRCm38)		probably null	Het
Amd1	C	T	10: 40,290,457 (GRCm38)	R210H	probably benign	Het
Amt	C	T	9: 108,297,221 (GRCm38)	R62C	possibly damaging	Het
Anapc1	A	G	2: 128,642,519 (GRCm38)	F1175S	probably damaging	Het
Ano4	A	G	10: 89,025,005 (GRCm38)	F337S	probably damaging	Het
Bub1	A	C	2: 127,821,942 (GRCm38)	I207S	probably benign	Het
Cfap53	T	A	18: 74,307,374 (GRCm38)	L405M	probably damaging	Het
Col1a2	G	A	6: 4,518,822 (GRCm38)		probably benign	Het
Col6a1	C	T	10: 76,711,341 (GRCm38)	R730H	unknown	Het
Esp3	A	T	17: 40,635,929 (GRCm38)	T48S	possibly damaging	Het
Fam35a	A	G	14: 34,259,709 (GRCm38)	W491R	probably damaging	Het
Fmo1	G	T	1: 162,833,768 (GRCm38)	N315K	possibly damaging	Het
Gm595	T	C	X: 48,841,544 (GRCm38)	N649S	possibly damaging	Het
Impg1	A	G	9: 80,345,585 (GRCm38)	S438P	possibly damaging	Het
Jsrp1	T	A	10: 80,812,412 (GRCm38)	M1L	probably benign	Het
Klra14-ps	T	A	6: 130,152,549 (GRCm38)		noncoding transcript	Het
Mrm3	A	G	11: 76,244,286 (GRCm38)	M108V	probably benign	Het
Mtf2	T	A	5: 108,081,000 (GRCm38)	F61I	probably damaging	Het
Nat10	A	T	2: 103,726,247 (GRCm38)		probably benign	Het
Olfr1356	T	G	10: 78,847,298 (GRCm38)	I206L	probably benign	Het
Olfr1380	T	C	11: 49,564,758 (GRCm38)	I279T	possibly damaging	Het
Pcgf5	T	C	19: 36,440,095 (GRCm38)	I140T	probably damaging	Het
Pfpl	T	C	19: 12,430,437 (GRCm38)	L684P	probably benign	Het
Psmd10	T	C	X: 140,949,303 (GRCm38)	*152W	probably null	Het
Ptpn23	A	C	9: 110,389,245 (GRCm38)	M600R	probably benign	Het
Pxmp4	C	T	2: 154,588,049 (GRCm38)	R140H	probably damaging	Het
Rnf112	T	C	11: 61,450,385 (GRCm38)	E410G	probably damaging	Het
Samd9l	T	A	6: 3,376,830 (GRCm38)	K144*	probably null	Het
Slc46a3	C	T	5: 147,886,454 (GRCm38)	E193K	probably benign	Het
Snap23	A	C	2: 120,599,334 (GRCm38)	D209A	possibly damaging	Het
Tg	C	T	15: 66,766,162 (GRCm38)	Q656*	probably null	Het
Tshz2	A	G	2: 169,884,387 (GRCm38)	Y301C	probably damaging	Het
Ttn	T	A	2: 76,840,294 (GRCm38)		probably benign	Het
Unc80	C	T	1: 66,639,296 (GRCm38)	Q2011*	probably null	Het
Vwa3a	A	G	7: 120,758,876 (GRCm38)	T57A	probably benign	Het
Zfp518a	C	T	19: 40,914,920 (GRCm38)	Q1098*	probably null	Het

Other mutations in Alms1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00227:Alms1	APN	6	85,677,964 (GRCm38)	missense	probably damaging	1.00
IGL00331:Alms1	APN	6	85,641,371 (GRCm38)	missense	possibly damaging	0.94
IGL00658:Alms1	APN	6	85,628,961 (GRCm38)	missense	probably damaging	1.00
IGL00835:Alms1	APN	6	85,622,134 (GRCm38)	missense	probably damaging	1.00
IGL00930:Alms1	APN	6	85,601,310 (GRCm38)	missense	probably damaging	0.98
IGL01446:Alms1	APN	6	85,696,701 (GRCm38)	missense	probably damaging	1.00
IGL01448:Alms1	APN	6	85,677,899 (GRCm38)	missense	possibly damaging	0.93
IGL01563:Alms1	APN	6	85,627,983 (GRCm38)	missense	probably damaging	1.00
IGL01632:Alms1	APN	6	85,627,946 (GRCm38)	missense	probably benign	0.07
IGL01651:Alms1	APN	6	85,656,476 (GRCm38)	missense	probably benign	0.05
IGL01670:Alms1	APN	6	85,678,150 (GRCm38)	missense	probably benign	0.00
IGL01716:Alms1	APN	6	85,628,094 (GRCm38)	missense	probably benign	0.01
IGL01719:Alms1	APN	6	85,628,094 (GRCm38)	missense	probably benign	0.01
IGL01720:Alms1	APN	6	85,628,094 (GRCm38)	missense	probably benign	0.01
IGL01723:Alms1	APN	6	85,628,094 (GRCm38)	missense	probably benign	0.01
IGL01877:Alms1	APN	6	85,622,411 (GRCm38)	missense	possibly damaging	0.55
IGL01919:Alms1	APN	6	85,628,004 (GRCm38)	missense	possibly damaging	0.77
IGL01976:Alms1	APN	6	85,622,665 (GRCm38)	missense	possibly damaging	0.73
IGL02003:Alms1	APN	6	85,622,223 (GRCm38)	missense	possibly damaging	0.54
IGL02069:Alms1	APN	6	85,628,823 (GRCm38)	missense	probably benign	0.12
IGL02070:Alms1	APN	6	85,651,403 (GRCm38)	missense	possibly damaging	0.74
IGL02079:Alms1	APN	6	85,628,634 (GRCm38)	missense	probably damaging	0.98
IGL02081:Alms1	APN	6	85,620,303 (GRCm38)	missense	possibly damaging	0.55
IGL02379:Alms1	APN	6	85,629,633 (GRCm38)	missense	probably damaging	0.98
IGL02412:Alms1	APN	6	85,628,872 (GRCm38)	missense	possibly damaging	0.91
IGL02606:Alms1	APN	6	85,599,967 (GRCm38)	missense	probably benign
IGL02636:Alms1	APN	6	85,628,654 (GRCm38)	missense	probably benign	0.28
IGL02702:Alms1	APN	6	85,599,849 (GRCm38)	missense	probably benign	0.12
IGL02815:Alms1	APN	6	85,667,957 (GRCm38)	critical splice donor site	probably null
IGL02926:Alms1	APN	6	85,641,450 (GRCm38)	missense	probably damaging	1.00
IGL02945:Alms1	APN	6	85,620,933 (GRCm38)	missense	probably damaging	0.96
IGL02959:Alms1	APN	6	85,629,052 (GRCm38)	nonsense	probably null
IGL03124:Alms1	APN	6	85,678,419 (GRCm38)	missense	probably benign	0.03
IGL03199:Alms1	APN	6	85,622,497 (GRCm38)	missense	possibly damaging	0.68
IGL03209:Alms1	APN	6	85,599,973 (GRCm38)	splice site	probably benign
IGL03247:Alms1	APN	6	85,678,597 (GRCm38)	missense	possibly damaging	0.85
ares	UTSW	6	85,621,275 (GRCm38)	nonsense	probably null
ares2	UTSW	6	85,677,990 (GRCm38)	nonsense	probably null
butterball	UTSW	6	85,696,771 (GRCm38)	missense	probably damaging	0.99
earthquake	UTSW	6	85,628,735 (GRCm38)	nonsense	probably null
fatty	UTSW	6	85,627,934 (GRCm38)	nonsense	probably null
gut_check	UTSW	6	85,620,369 (GRCm38)	nonsense	probably null
portly	UTSW	6	85,619,712 (GRCm38)	missense	probably benign	0.00
replete	UTSW	6	85,629,208 (GRCm38)	missense	possibly damaging	0.87
PIT4468001:Alms1	UTSW	6	85,624,719 (GRCm38)	critical splice donor site	probably null
R0003:Alms1	UTSW	6	85,629,210 (GRCm38)	missense	possibly damaging	0.90
R0095:Alms1	UTSW	6	85,620,253 (GRCm38)	missense	possibly damaging	0.90
R0110:Alms1	UTSW	6	85,620,369 (GRCm38)	nonsense	probably null
R0114:Alms1	UTSW	6	85,619,803 (GRCm38)	missense	probably benign	0.00
R0153:Alms1	UTSW	6	85,641,381 (GRCm38)	missense	possibly damaging	0.94
R0217:Alms1	UTSW	6	85,622,930 (GRCm38)	missense	probably damaging	0.99
R0328:Alms1	UTSW	6	85,610,814 (GRCm38)	splice site	probably null
R0410:Alms1	UTSW	6	85,587,803 (GRCm38)	missense	unknown
R0469:Alms1	UTSW	6	85,620,369 (GRCm38)	nonsense	probably null
R0491:Alms1	UTSW	6	85,702,600 (GRCm38)	missense	probably damaging	0.98
R0510:Alms1	UTSW	6	85,620,369 (GRCm38)	nonsense	probably null
R0522:Alms1	UTSW	6	85,621,615 (GRCm38)	missense	probably benign
R0525:Alms1	UTSW	6	85,587,760 (GRCm38)	missense	unknown
R0611:Alms1	UTSW	6	85,678,671 (GRCm38)	missense	possibly damaging	0.61
R0637:Alms1	UTSW	6	85,623,033 (GRCm38)	missense	possibly damaging	0.85
R0718:Alms1	UTSW	6	85,621,821 (GRCm38)	missense	probably benign	0.00
R0831:Alms1	UTSW	6	85,628,520 (GRCm38)	missense	probably benign	0.00
R1318:Alms1	UTSW	6	85,628,549 (GRCm38)	missense	possibly damaging	0.62
R1340:Alms1	UTSW	6	85,667,957 (GRCm38)	critical splice donor site	probably null
R1561:Alms1	UTSW	6	85,629,052 (GRCm38)	nonsense	probably null
R1648:Alms1	UTSW	6	85,678,402 (GRCm38)	missense	probably damaging	0.99
R1697:Alms1	UTSW	6	85,622,454 (GRCm38)	missense	possibly damaging	0.94
R1699:Alms1	UTSW	6	85,622,880 (GRCm38)	missense	possibly damaging	0.46
R1715:Alms1	UTSW	6	85,629,052 (GRCm38)	nonsense	probably null
R1723:Alms1	UTSW	6	85,628,753 (GRCm38)	missense	probably damaging	1.00
R1734:Alms1	UTSW	6	85,641,550 (GRCm38)	critical splice donor site	probably null
R1758:Alms1	UTSW	6	85,628,505 (GRCm38)	missense	probably damaging	0.99
R1804:Alms1	UTSW	6	85,621,275 (GRCm38)	nonsense	probably null
R1835:Alms1	UTSW	6	85,678,503 (GRCm38)	missense	possibly damaging	0.94
R1836:Alms1	UTSW	6	85,678,503 (GRCm38)	missense	possibly damaging	0.94
R2077:Alms1	UTSW	6	85,622,309 (GRCm38)	missense	possibly damaging	0.93
R2246:Alms1	UTSW	6	85,622,967 (GRCm38)	missense	possibly damaging	0.91
R2254:Alms1	UTSW	6	85,619,848 (GRCm38)	missense	probably damaging	1.00
R2280:Alms1	UTSW	6	85,677,973 (GRCm38)	missense	probably damaging	0.99
R2516:Alms1	UTSW	6	85,667,963 (GRCm38)	splice site	probably benign
R2519:Alms1	UTSW	6	85,667,963 (GRCm38)	splice site	probably benign
R2566:Alms1	UTSW	6	85,622,482 (GRCm38)	missense	possibly damaging	0.84
R2850:Alms1	UTSW	6	85,667,963 (GRCm38)	splice site	probably benign
R2850:Alms1	UTSW	6	85,621,299 (GRCm38)	missense	probably benign	0.00
R2932:Alms1	UTSW	6	85,620,562 (GRCm38)	missense	possibly damaging	0.89
R2944:Alms1	UTSW	6	85,628,391 (GRCm38)	missense	probably damaging	1.00
R2980:Alms1	UTSW	6	85,628,835 (GRCm38)	missense	probably damaging	1.00
R3084:Alms1	UTSW	6	85,678,140 (GRCm38)	missense	probably benign
R3086:Alms1	UTSW	6	85,678,140 (GRCm38)	missense	probably benign
R3122:Alms1	UTSW	6	85,667,963 (GRCm38)	splice site	probably benign
R3404:Alms1	UTSW	6	85,667,963 (GRCm38)	splice site	probably benign
R3405:Alms1	UTSW	6	85,667,963 (GRCm38)	splice site	probably benign
R3804:Alms1	UTSW	6	85,619,647 (GRCm38)	missense	probably damaging	1.00
R4014:Alms1	UTSW	6	85,678,352 (GRCm38)	missense	probably benign	0.41
R4056:Alms1	UTSW	6	85,587,803 (GRCm38)	missense	unknown
R4067:Alms1	UTSW	6	85,621,289 (GRCm38)	missense	probably damaging	1.00
R4110:Alms1	UTSW	6	85,620,888 (GRCm38)	missense	probably benign	0.00
R4111:Alms1	UTSW	6	85,620,888 (GRCm38)	missense	probably benign	0.00
R4112:Alms1	UTSW	6	85,620,888 (GRCm38)	missense	probably benign	0.00
R4194:Alms1	UTSW	6	85,677,990 (GRCm38)	nonsense	probably null
R4464:Alms1	UTSW	6	85,620,021 (GRCm38)	missense	possibly damaging	0.66
R4539:Alms1	UTSW	6	85,620,478 (GRCm38)	missense	possibly damaging	0.78
R4554:Alms1	UTSW	6	85,624,617 (GRCm38)	missense	probably benign
R4696:Alms1	UTSW	6	85,620,522 (GRCm38)	missense	probably damaging	1.00
R4825:Alms1	UTSW	6	85,678,245 (GRCm38)	missense	probably damaging	0.99
R4921:Alms1	UTSW	6	85,628,546 (GRCm38)	missense	probably benign	0.13
R5030:Alms1	UTSW	6	85,627,964 (GRCm38)	missense	probably damaging	0.98
R5051:Alms1	UTSW	6	85,627,934 (GRCm38)	nonsense	probably null
R5085:Alms1	UTSW	6	85,620,732 (GRCm38)	missense	possibly damaging	0.55
R5141:Alms1	UTSW	6	85,621,432 (GRCm38)	missense	probably benign	0.01
R5233:Alms1	UTSW	6	85,656,371 (GRCm38)	splice site	probably null
R5310:Alms1	UTSW	6	85,615,368 (GRCm38)	missense	possibly damaging	0.79
R5344:Alms1	UTSW	6	85,696,789 (GRCm38)	missense	probably benign	0.04
R5394:Alms1	UTSW	6	85,623,088 (GRCm38)	missense	probably benign	0.01
R5460:Alms1	UTSW	6	85,696,731 (GRCm38)	missense	probably benign	0.08
R5558:Alms1	UTSW	6	85,641,329 (GRCm38)	nonsense	probably null
R5650:Alms1	UTSW	6	85,620,271 (GRCm38)	missense	probably damaging	1.00
R5667:Alms1	UTSW	6	85,696,771 (GRCm38)	missense	probably damaging	0.99
R5671:Alms1	UTSW	6	85,629,208 (GRCm38)	missense	possibly damaging	0.87
R5688:Alms1	UTSW	6	85,599,895 (GRCm38)	missense	possibly damaging	0.92
R5815:Alms1	UTSW	6	85,622,838 (GRCm38)	missense	probably damaging	0.99
R5892:Alms1	UTSW	6	85,620,903 (GRCm38)	missense	probably damaging	0.99
R5947:Alms1	UTSW	6	85,619,712 (GRCm38)	missense	probably benign	0.00
R6031:Alms1	UTSW	6	85,622,955 (GRCm38)	missense	probably damaging	1.00
R6031:Alms1	UTSW	6	85,622,955 (GRCm38)	missense	probably damaging	1.00
R6144:Alms1	UTSW	6	85,623,074 (GRCm38)	missense	probably damaging	0.98
R6258:Alms1	UTSW	6	85,628,735 (GRCm38)	nonsense	probably null
R6260:Alms1	UTSW	6	85,628,735 (GRCm38)	nonsense	probably null
R6455:Alms1	UTSW	6	85,696,657 (GRCm38)	missense	probably damaging	0.99
R6569:Alms1	UTSW	6	85,641,339 (GRCm38)	missense	probably benign	0.07
R6637:Alms1	UTSW	6	85,619,734 (GRCm38)	missense	possibly damaging	0.78
R6866:Alms1	UTSW	6	85,621,098 (GRCm38)	missense	possibly damaging	0.85
R6918:Alms1	UTSW	6	85,622,661 (GRCm38)	missense	possibly damaging	0.87
R7121:Alms1	UTSW	6	85,624,622 (GRCm38)	missense	probably damaging	1.00
R7179:Alms1	UTSW	6	85,621,369 (GRCm38)	missense	probably benign	0.09
R7334:Alms1	UTSW	6	85,641,450 (GRCm38)	missense	probably damaging	0.99
R7376:Alms1	UTSW	6	85,622,106 (GRCm38)	missense	probably benign	0.10
R7394:Alms1	UTSW	6	85,622,223 (GRCm38)	missense	possibly damaging	0.54
R7413:Alms1	UTSW	6	85,628,306 (GRCm38)	missense	probably benign	0.03
R7511:Alms1	UTSW	6	85,609,425 (GRCm38)	missense	unknown
R7542:Alms1	UTSW	6	85,629,362 (GRCm38)	missense	possibly damaging	0.62
R7562:Alms1	UTSW	6	85,620,412 (GRCm38)	missense	probably damaging	1.00
R7575:Alms1	UTSW	6	85,622,159 (GRCm38)	missense	possibly damaging	0.49
R7577:Alms1	UTSW	6	85,615,320 (GRCm38)	missense	probably benign	0.09
R7618:Alms1	UTSW	6	85,678,417 (GRCm38)	missense	probably benign	0.07
R7653:Alms1	UTSW	6	85,620,595 (GRCm38)	missense	possibly damaging	0.47
R7672:Alms1	UTSW	6	85,615,351 (GRCm38)	missense	probably damaging	1.00
R7807:Alms1	UTSW	6	85,622,976 (GRCm38)	missense	possibly damaging	0.91
R7815:Alms1	UTSW	6	85,615,358 (GRCm38)	missense	probably benign	0.42
R7849:Alms1	UTSW	6	85,621,497 (GRCm38)	missense	possibly damaging	0.48
R7944:Alms1	UTSW	6	85,641,380 (GRCm38)	missense	probably benign	0.03
R7954:Alms1	UTSW	6	85,621,162 (GRCm38)	missense	probably damaging	0.98
R7971:Alms1	UTSW	6	85,628,679 (GRCm38)	missense	probably benign
R8048:Alms1	UTSW	6	85,641,334 (GRCm38)	missense	probably benign	0.13
R8223:Alms1	UTSW	6	85,643,240 (GRCm38)	nonsense	probably null
R8332:Alms1	UTSW	6	85,620,579 (GRCm38)	missense	probably benign	0.05
R8374:Alms1	UTSW	6	85,608,991 (GRCm38)	missense	probably benign	0.41
R8470:Alms1	UTSW	6	85,641,375 (GRCm38)	missense	probably damaging	0.99
R8755:Alms1	UTSW	6	85,621,574 (GRCm38)	missense	probably benign	0.01
R8979:Alms1	UTSW	6	85,621,027 (GRCm38)	missense	probably damaging	0.98
R9044:Alms1	UTSW	6	85,696,753 (GRCm38)	missense	probably damaging	0.98
R9057:Alms1	UTSW	6	85,609,832 (GRCm38)	missense	unknown
R9224:Alms1	UTSW	6	85,621,788 (GRCm38)	missense	possibly damaging	0.69
R9259:Alms1	UTSW	6	85,667,891 (GRCm38)	missense	possibly damaging	0.94
R9401:Alms1	UTSW	6	85,678,019 (GRCm38)	nonsense	probably null
R9459:Alms1	UTSW	6	85,627,964 (GRCm38)	missense	probably damaging	0.98
R9633:Alms1	UTSW	6	85,623,143 (GRCm38)	missense	probably damaging	0.99
R9716:Alms1	UTSW	6	85,601,252 (GRCm38)	missense	possibly damaging	0.84
R9730:Alms1	UTSW	6	85,629,438 (GRCm38)	missense	probably benign	0.00
R9790:Alms1	UTSW	6	85,619,443 (GRCm38)	missense	probably benign	0.04
R9791:Alms1	UTSW	6	85,619,443 (GRCm38)	missense	probably benign	0.04
R9802:Alms1	UTSW	6	85,629,238 (GRCm38)	missense	possibly damaging	0.61
X0013:Alms1	UTSW	6	85,656,455 (GRCm38)	missense	probably damaging	1.00
X0025:Alms1	UTSW	6	85,620,210 (GRCm38)	missense	probably damaging	0.96
Z1176:Alms1	UTSW	6	85,678,418 (GRCm38)	missense	probably benign	0.41

Predicted Primers

PCR Primer
(F):5'- AAATCAGTAGGCTCTGGCTC -3'
(R):5'- ACTCGGCTGTCTGGCAATTC -3'

Sequencing Primer
(F):5'- TGGGGCACAAATAGTCTCCTC -3'
(R):5'- TGTCTGGCAATTCAGCAAAGC -3'

Posted On

2015-04-17