Incidental Mutation 'R3916:Cadps'
| ID |
309772 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Cadps
|
| Ensembl Gene |
ENSMUSG00000054423 |
| Gene Name |
Ca2+-dependent secretion activator |
| Synonyms |
CAPS1 |
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R3916 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
14 |
| Chromosomal Location |
12372563-12823079 bp(-) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to T
at 12457702 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Alanine to Threonine
at position 1060
(A1060T)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000064706
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000067491]
[ENSMUST00000112657]
[ENSMUST00000112658]
[ENSMUST00000177814]
[ENSMUST00000224882]
|
| AlphaFold |
Q80TJ1 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000067491
AA Change: A1060T
PolyPhen 2
Score 0.003 (Sensitivity: 0.98; Specificity: 0.44)
|
| SMART Domains |
Protein: ENSMUSP00000064706
Gene: ENSMUSG00000054423
AA Change: A1060T
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
5 |
18 |
N/A |
INTRINSIC |
|
low complexity region
|
41 |
75 |
N/A |
INTRINSIC |
|
coiled coil region
|
93 |
121 |
N/A |
INTRINSIC |
|
C2
|
397 |
492 |
1.08e-2 |
SMART |
|
PH
|
520 |
624 |
1.78e-10 |
SMART |
|
low complexity region
|
772 |
783 |
N/A |
INTRINSIC |
|
DUF1041
|
833 |
948 |
6.21e-54 |
SMART |
|
low complexity region
|
1022 |
1045 |
N/A |
INTRINSIC |
|
low complexity region
|
1354 |
1361 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000112657
AA Change: A1053T
PolyPhen 2
Score 0.002 (Sensitivity: 0.99; Specificity: 0.30)
|
| SMART Domains |
Protein: ENSMUSP00000108276
Gene: ENSMUSG00000054423
AA Change: A1053T
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
5 |
18 |
N/A |
INTRINSIC |
|
low complexity region
|
41 |
75 |
N/A |
INTRINSIC |
|
coiled coil region
|
93 |
121 |
N/A |
INTRINSIC |
|
C2
|
397 |
492 |
1.08e-2 |
SMART |
|
PH
|
520 |
624 |
1.78e-10 |
SMART |
|
low complexity region
|
775 |
786 |
N/A |
INTRINSIC |
|
DUF1041
|
836 |
941 |
3.88e-55 |
SMART |
|
low complexity region
|
1015 |
1038 |
N/A |
INTRINSIC |
|
low complexity region
|
1347 |
1354 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000112658
AA Change: A1054T
PolyPhen 2
Score 0.002 (Sensitivity: 0.99; Specificity: 0.30)
|
| SMART Domains |
Protein: ENSMUSP00000108277
Gene: ENSMUSG00000054423
AA Change: A1054T
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
5 |
18 |
N/A |
INTRINSIC |
|
low complexity region
|
41 |
75 |
N/A |
INTRINSIC |
|
coiled coil region
|
93 |
121 |
N/A |
INTRINSIC |
|
C2
|
397 |
492 |
1.08e-2 |
SMART |
|
PH
|
520 |
624 |
1.78e-10 |
SMART |
|
low complexity region
|
776 |
787 |
N/A |
INTRINSIC |
|
DUF1041
|
837 |
942 |
3.88e-55 |
SMART |
|
low complexity region
|
1016 |
1039 |
N/A |
INTRINSIC |
|
low complexity region
|
1348 |
1355 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000177814
AA Change: A1055T
PolyPhen 2
Score 0.002 (Sensitivity: 0.99; Specificity: 0.30)
|
| SMART Domains |
Protein: ENSMUSP00000136076
Gene: ENSMUSG00000054423
AA Change: A1055T
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
5 |
18 |
N/A |
INTRINSIC |
|
low complexity region
|
41 |
75 |
N/A |
INTRINSIC |
|
coiled coil region
|
93 |
121 |
N/A |
INTRINSIC |
|
C2
|
397 |
492 |
1.08e-2 |
SMART |
|
PH
|
520 |
624 |
1.78e-10 |
SMART |
|
low complexity region
|
777 |
788 |
N/A |
INTRINSIC |
|
DUF1041
|
838 |
943 |
2.75e-55 |
SMART |
|
low complexity region
|
1017 |
1040 |
N/A |
INTRINSIC |
|
low complexity region
|
1349 |
1356 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000224106
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000224581
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000224882
|
| Meta Mutation Damage Score |
0.0604 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.4%
- 20x: 95.4%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a novel neural/endocrine-specific cytosolic and peripheral membrane protein required for the Ca2+-regulated exocytosis of secretory vesicles. The protein acts at a stage in exocytosis that follows ATP-dependent priming, which involves the essential synthesis of phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Alternative splicing has been observed at this locus and three variants, encoding distinct isoforms, are described. [provided by RefSeq, Aug 2008]
PHENOTYPE: Homozygous null mice display neonatal lethality, respiratory failure and abnormal adrenal gland physiology. Adult heterozygous null mice display abnormal adrenal gland physiology that is different from that seen in homozygous neonates. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 64 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4932414N04Rik |
T |
G |
2: 68,731,985 (GRCm38) |
F319V |
possibly damaging |
Het |
| Acad12 |
A |
G |
5: 121,599,214 (GRCm38) |
V498A |
probably damaging |
Het |
| Adam19 |
A |
G |
11: 46,060,935 (GRCm38) |
E37G |
probably benign |
Het |
| Anks3 |
A |
G |
16: 4,947,279 (GRCm38) |
Y423H |
probably damaging |
Het |
| Arfgef1 |
A |
T |
1: 10,189,443 (GRCm38) |
V600D |
probably benign |
Het |
| Arhgef18 |
T |
C |
8: 3,454,197 (GRCm38) |
F939L |
probably benign |
Het |
| Arhgef2 |
A |
G |
3: 88,633,033 (GRCm38) |
N127S |
probably damaging |
Het |
| Arid1b |
A |
G |
17: 5,342,653 (GRCm38) |
S2100G |
probably benign |
Het |
| Atp1b2 |
A |
G |
11: 69,603,075 (GRCm38) |
V93A |
probably damaging |
Het |
| Atrnl1 |
T |
C |
19: 57,935,652 (GRCm38) |
V1283A |
possibly damaging |
Het |
| Bpifb5 |
A |
C |
2: 154,228,181 (GRCm38) |
K184Q |
probably benign |
Het |
| Cant1 |
A |
G |
11: 118,408,746 (GRCm38) |
V259A |
probably damaging |
Het |
| Ccdc89 |
A |
G |
7: 90,426,825 (GRCm38) |
D81G |
probably damaging |
Het |
| Cd109 |
CATTTATTTATTTATTTATTTATTTATTTATTTAT |
CATTTATTTATTTATTTATTTATTTATTTATTTATTTAT |
9: 78,712,500 (GRCm38) |
|
probably benign |
Het |
| Cntnap4 |
C |
G |
8: 112,875,533 (GRCm38) |
P1190A |
probably benign |
Het |
| Colgalt2 |
T |
A |
1: 152,508,611 (GRCm38) |
Y567* |
probably null |
Het |
| Cyp4f18 |
A |
T |
8: 71,996,037 (GRCm38) |
F256Y |
probably benign |
Het |
| Ddx41 |
G |
A |
13: 55,534,480 (GRCm38) |
R205W |
possibly damaging |
Het |
| Dop1a |
G |
A |
9: 86,521,133 (GRCm38) |
R1462H |
probably damaging |
Het |
| Dync1i2 |
A |
G |
2: 71,249,372 (GRCm38) |
T377A |
probably damaging |
Het |
| F2 |
G |
A |
2: 91,625,488 (GRCm38) |
T600M |
probably damaging |
Het |
| Fam91a1 |
C |
T |
15: 58,430,734 (GRCm38) |
H308Y |
probably damaging |
Het |
| Fkbp2 |
C |
A |
19: 6,978,557 (GRCm38) |
|
probably null |
Het |
| Gabarapl2 |
T |
A |
8: 111,952,396 (GRCm38) |
F115L |
probably benign |
Het |
| Heatr3 |
T |
G |
8: 88,150,371 (GRCm38) |
|
probably null |
Het |
| Ifi204 |
T |
G |
1: 173,755,775 (GRCm38) |
K292N |
possibly damaging |
Het |
| Itpkc |
A |
T |
7: 27,228,303 (GRCm38) |
I62N |
probably benign |
Het |
| Kcnab1 |
G |
A |
3: 65,304,164 (GRCm38) |
|
probably null |
Het |
| Krt88 |
G |
A |
15: 101,452,928 (GRCm38) |
|
probably null |
Het |
| Larp4 |
C |
T |
15: 99,990,403 (GRCm38) |
T107I |
probably benign |
Het |
| Lmo7 |
T |
C |
14: 101,929,342 (GRCm38) |
|
probably benign |
Het |
| Lrrc37a |
T |
C |
11: 103,455,518 (GRCm38) |
Y3174C |
possibly damaging |
Het |
| Lyzl4 |
T |
A |
9: 121,583,035 (GRCm38) |
D105V |
probably damaging |
Het |
| Mst1 |
A |
G |
9: 108,084,295 (GRCm38) |
I575V |
probably benign |
Het |
| Myh7 |
C |
A |
14: 54,974,046 (GRCm38) |
E1555D |
probably damaging |
Het |
| Nwd1 |
T |
A |
8: 72,667,811 (GRCm38) |
C608* |
probably null |
Het |
| Obox3 |
C |
A |
7: 15,627,226 (GRCm38) |
C38F |
probably benign |
Het |
| P4ha2 |
A |
G |
11: 54,126,248 (GRCm38) |
D441G |
probably benign |
Het |
| Pcdhb14 |
A |
T |
18: 37,448,545 (GRCm38) |
I235F |
possibly damaging |
Het |
| Rasgrf2 |
A |
G |
13: 92,030,788 (GRCm38) |
V259A |
probably damaging |
Het |
| Scn1a |
T |
C |
2: 66,277,613 (GRCm38) |
T1590A |
probably damaging |
Het |
| Sdk1 |
T |
A |
5: 142,051,244 (GRCm38) |
D817E |
probably damaging |
Het |
| Sema3b |
A |
G |
9: 107,600,458 (GRCm38) |
F482S |
probably damaging |
Het |
| Slc35a5 |
G |
C |
16: 45,158,158 (GRCm38) |
|
probably benign |
Het |
| Slc6a3 |
A |
G |
13: 73,562,308 (GRCm38) |
I346V |
probably benign |
Het |
| Slu7 |
G |
T |
11: 43,440,684 (GRCm38) |
|
probably null |
Het |
| Spns1 |
A |
T |
7: 126,371,539 (GRCm38) |
|
probably null |
Het |
| Supv3l1 |
T |
C |
10: 62,449,420 (GRCm38) |
D89G |
possibly damaging |
Het |
| Taf1c |
G |
A |
8: 119,600,505 (GRCm38) |
R412W |
probably damaging |
Het |
| Tctn3 |
T |
A |
19: 40,607,649 (GRCm38) |
T305S |
possibly damaging |
Het |
| Tekt1 |
A |
G |
11: 72,345,748 (GRCm38) |
I296T |
possibly damaging |
Het |
| Tet2 |
T |
C |
3: 133,486,055 (GRCm38) |
K873E |
possibly damaging |
Het |
| Thada |
G |
A |
17: 84,441,782 (GRCm38) |
A587V |
possibly damaging |
Het |
| Tmprss15 |
T |
A |
16: 78,985,996 (GRCm38) |
N712Y |
probably damaging |
Het |
| Tnks |
A |
G |
8: 34,853,361 (GRCm38) |
S719P |
probably damaging |
Het |
| Tnrc6a |
A |
C |
7: 123,181,384 (GRCm38) |
Q1332H |
probably damaging |
Het |
| Trpv3 |
A |
G |
11: 73,283,734 (GRCm38) |
D309G |
possibly damaging |
Het |
| Tti2 |
A |
G |
8: 31,153,519 (GRCm38) |
K221E |
possibly damaging |
Het |
| Uba5 |
A |
T |
9: 104,054,190 (GRCm38) |
C227S |
probably damaging |
Het |
| Ugcg |
C |
T |
4: 59,207,798 (GRCm38) |
P46S |
probably benign |
Het |
| Unc80 |
T |
C |
1: 66,677,495 (GRCm38) |
C2925R |
probably benign |
Het |
| Vmn2r83 |
G |
A |
10: 79,478,910 (GRCm38) |
G331R |
probably benign |
Het |
| Xirp2 |
G |
T |
2: 67,511,422 (GRCm38) |
V1336F |
probably benign |
Het |
| Zbed5 |
T |
C |
5: 129,902,277 (GRCm38) |
Y356H |
possibly damaging |
Het |
|
| Other mutations in Cadps |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00926:Cadps
|
APN |
14 |
12,491,795 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL00990:Cadps
|
APN |
14 |
12,715,374 (GRCm38) |
missense |
possibly damaging |
0.56 |
|
IGL01071:Cadps
|
APN |
14 |
12,509,091 (GRCm38) |
splice site |
probably null |
|
|
IGL01339:Cadps
|
APN |
14 |
12,486,543 (GRCm38) |
missense |
possibly damaging |
0.58 |
|
IGL01518:Cadps
|
APN |
14 |
12,522,352 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01560:Cadps
|
APN |
14 |
12,491,792 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01598:Cadps
|
APN |
14 |
12,522,202 (GRCm38) |
critical splice donor site |
probably null |
|
|
IGL01603:Cadps
|
APN |
14 |
12,454,154 (GRCm38) |
splice site |
probably benign |
|
|
IGL01836:Cadps
|
APN |
14 |
12,522,311 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01839:Cadps
|
APN |
14 |
12,467,184 (GRCm38) |
splice site |
probably benign |
|
|
IGL01932:Cadps
|
APN |
14 |
12,373,609 (GRCm38) |
utr 3 prime |
probably benign |
|
|
IGL02172:Cadps
|
APN |
14 |
12,705,681 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02175:Cadps
|
APN |
14 |
12,467,092 (GRCm38) |
missense |
probably damaging |
0.96 |
|
IGL02212:Cadps
|
APN |
14 |
12,522,345 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
IGL02351:Cadps
|
APN |
14 |
12,597,380 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL02358:Cadps
|
APN |
14 |
12,597,380 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL02499:Cadps
|
APN |
14 |
12,822,725 (GRCm38) |
nonsense |
probably null |
|
|
IGL02505:Cadps
|
APN |
14 |
12,449,759 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02591:Cadps
|
APN |
14 |
12,473,465 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02592:Cadps
|
APN |
14 |
12,473,465 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02671:Cadps
|
APN |
14 |
12,491,824 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02956:Cadps
|
APN |
14 |
12,418,047 (GRCm38) |
splice site |
probably benign |
|
|
IGL03029:Cadps
|
APN |
14 |
12,376,675 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03216:Cadps
|
APN |
14 |
12,439,944 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03282:Cadps
|
APN |
14 |
12,465,856 (GRCm38) |
splice site |
probably benign |
|
|
turbo
|
UTSW |
14 |
12,491,800 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0241:Cadps
|
UTSW |
14 |
12,376,675 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0241:Cadps
|
UTSW |
14 |
12,376,675 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0420:Cadps
|
UTSW |
14 |
12,491,800 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1180:Cadps
|
UTSW |
14 |
12,457,836 (GRCm38) |
splice site |
probably benign |
|
|
R1398:Cadps
|
UTSW |
14 |
12,449,822 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1678:Cadps
|
UTSW |
14 |
12,517,802 (GRCm38) |
critical splice donor site |
probably null |
|
|
R1792:Cadps
|
UTSW |
14 |
12,449,802 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R1863:Cadps
|
UTSW |
14 |
12,505,796 (GRCm38) |
missense |
probably benign |
0.09 |
|
R1863:Cadps
|
UTSW |
14 |
12,449,802 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R1918:Cadps
|
UTSW |
14 |
12,546,372 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1920:Cadps
|
UTSW |
14 |
12,465,859 (GRCm38) |
missense |
possibly damaging |
0.64 |
|
R1921:Cadps
|
UTSW |
14 |
12,465,859 (GRCm38) |
missense |
possibly damaging |
0.64 |
|
R1922:Cadps
|
UTSW |
14 |
12,465,859 (GRCm38) |
missense |
possibly damaging |
0.64 |
|
R1925:Cadps
|
UTSW |
14 |
12,705,726 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1966:Cadps
|
UTSW |
14 |
12,822,450 (GRCm38) |
nonsense |
probably null |
|
|
R2013:Cadps
|
UTSW |
14 |
12,522,337 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2228:Cadps
|
UTSW |
14 |
12,465,935 (GRCm38) |
missense |
probably benign |
0.05 |
|
R2331:Cadps
|
UTSW |
14 |
12,603,692 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3436:Cadps
|
UTSW |
14 |
12,616,158 (GRCm38) |
splice site |
probably null |
|
|
R3853:Cadps
|
UTSW |
14 |
12,509,090 (GRCm38) |
splice site |
probably benign |
|
|
R3893:Cadps
|
UTSW |
14 |
12,488,883 (GRCm38) |
utr 3 prime |
probably benign |
|
|
R3917:Cadps
|
UTSW |
14 |
12,457,702 (GRCm38) |
missense |
probably benign |
0.00 |
|
R3953:Cadps
|
UTSW |
14 |
12,505,937 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3966:Cadps
|
UTSW |
14 |
12,522,161 (GRCm38) |
splice site |
probably null |
|
|
R4024:Cadps
|
UTSW |
14 |
12,705,539 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4079:Cadps
|
UTSW |
14 |
12,457,702 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4230:Cadps
|
UTSW |
14 |
12,488,987 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R4333:Cadps
|
UTSW |
14 |
12,467,031 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4410:Cadps
|
UTSW |
14 |
12,822,323 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R4586:Cadps
|
UTSW |
14 |
12,505,808 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4685:Cadps
|
UTSW |
14 |
12,467,139 (GRCm38) |
missense |
possibly damaging |
0.77 |
|
R4698:Cadps
|
UTSW |
14 |
12,705,654 (GRCm38) |
missense |
possibly damaging |
0.90 |
|
R4855:Cadps
|
UTSW |
14 |
12,822,449 (GRCm38) |
missense |
unknown |
|
|
R4898:Cadps
|
UTSW |
14 |
12,411,588 (GRCm38) |
missense |
possibly damaging |
0.86 |
|
R4908:Cadps
|
UTSW |
14 |
12,536,386 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5208:Cadps
|
UTSW |
14 |
12,457,711 (GRCm38) |
missense |
possibly damaging |
0.68 |
|
R5297:Cadps
|
UTSW |
14 |
12,822,345 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5328:Cadps
|
UTSW |
14 |
12,457,790 (GRCm38) |
missense |
probably benign |
0.31 |
|
R5408:Cadps
|
UTSW |
14 |
12,705,759 (GRCm38) |
missense |
possibly damaging |
0.87 |
|
R5529:Cadps
|
UTSW |
14 |
12,454,285 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5567:Cadps
|
UTSW |
14 |
12,473,497 (GRCm38) |
missense |
possibly damaging |
0.49 |
|
R5570:Cadps
|
UTSW |
14 |
12,473,497 (GRCm38) |
missense |
possibly damaging |
0.49 |
|
R5727:Cadps
|
UTSW |
14 |
12,486,525 (GRCm38) |
nonsense |
probably null |
|
|
R5812:Cadps
|
UTSW |
14 |
12,376,685 (GRCm38) |
missense |
probably benign |
|
|
R6361:Cadps
|
UTSW |
14 |
12,491,778 (GRCm38) |
nonsense |
probably null |
|
|
R6767:Cadps
|
UTSW |
14 |
12,550,888 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6805:Cadps
|
UTSW |
14 |
12,467,103 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R6861:Cadps
|
UTSW |
14 |
12,522,401 (GRCm38) |
nonsense |
probably null |
|
|
R6883:Cadps
|
UTSW |
14 |
12,465,883 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R6887:Cadps
|
UTSW |
14 |
12,505,811 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6997:Cadps
|
UTSW |
14 |
12,505,793 (GRCm38) |
missense |
possibly damaging |
0.88 |
|
R7102:Cadps
|
UTSW |
14 |
12,603,738 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7120:Cadps
|
UTSW |
14 |
12,439,919 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R7143:Cadps
|
UTSW |
14 |
12,491,838 (GRCm38) |
missense |
probably benign |
0.02 |
|
R7290:Cadps
|
UTSW |
14 |
12,616,099 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7614:Cadps
|
UTSW |
14 |
12,454,260 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7674:Cadps
|
UTSW |
14 |
12,411,581 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R7715:Cadps
|
UTSW |
14 |
12,457,762 (GRCm38) |
missense |
probably benign |
0.01 |
|
R7801:Cadps
|
UTSW |
14 |
12,489,476 (GRCm38) |
critical splice donor site |
probably null |
|
|
R7814:Cadps
|
UTSW |
14 |
12,376,706 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R7915:Cadps
|
UTSW |
14 |
12,705,544 (GRCm38) |
missense |
possibly damaging |
0.84 |
|
R8087:Cadps
|
UTSW |
14 |
12,536,380 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8109:Cadps
|
UTSW |
14 |
12,488,975 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8485:Cadps
|
UTSW |
14 |
12,439,872 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9156:Cadps
|
UTSW |
14 |
12,705,676 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9158:Cadps
|
UTSW |
14 |
12,546,356 (GRCm38) |
missense |
probably benign |
0.10 |
|
R9312:Cadps
|
UTSW |
14 |
12,616,095 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9465:Cadps
|
UTSW |
14 |
12,489,002 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R9519:Cadps
|
UTSW |
14 |
12,546,290 (GRCm38) |
missense |
possibly damaging |
0.86 |
|
R9649:Cadps
|
UTSW |
14 |
12,597,418 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R9662:Cadps
|
UTSW |
14 |
12,411,567 (GRCm38) |
missense |
probably benign |
0.02 |
|
R9674:Cadps
|
UTSW |
14 |
12,454,291 (GRCm38) |
missense |
probably damaging |
1.00 |
|
X0018:Cadps
|
UTSW |
14 |
12,373,690 (GRCm38) |
missense |
probably damaging |
1.00 |
|
X0028:Cadps
|
UTSW |
14 |
12,467,118 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
Z1088:Cadps
|
UTSW |
14 |
12,467,113 (GRCm38) |
missense |
probably damaging |
0.96 |
|
Z1177:Cadps
|
UTSW |
14 |
12,465,880 (GRCm38) |
missense |
probably damaging |
0.99 |
|
| Predicted Primers |
PCR Primer
(F):5'- GTGGGTGTTAGACAAATCGTTAC -3'
(R):5'- GCCGCATCTACATTGTCACTG -3'
Sequencing Primer
(F):5'- GTCTTATAAACACGATGAATGCCAG -3'
(R):5'- CGCATCTACATTGTCACTGTGATGG -3'
|
| Posted On |
2015-04-17 |
Incidental Mutation