Mutagenetix > Incidental Mutation

Incidental Mutation 'R3749:Dnah8'

310120

Institutional Source

Beutler Lab

Gene Symbol

Dnah8

Ensembl Gene

ENSMUSG00000033826

Gene Name

dynein, axonemal, heavy chain 8

Synonyms

Dnahc8, P1-Loop, Hst6.7b

MMRRC Submission

040734-MU

Accession Numbers

Essential gene?

Possibly non essential (E-score: 0.423) question?

Stock #

R3749 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

30624354-30875264 bp(+) (GRCm38)

Type of Mutation

nonsense

DNA Base Change (assembly)

A to T at 30784174 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Lysine to Stop codon at position 3616 (K3616*)

Ref Sequence

ENSEMBL: ENSMUSP00000127878 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000170651]

AlphaFold

no structure available at present

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000083205

Predicted Effect

probably null
Transcript: ENSMUST00000170651
AA Change: K3616*

SMART Domains

Protein: ENSMUSP00000127878
Gene: ENSMUSG00000033826
AA Change: K3616*

Domain	Start	End	E-Value	Type
low complexity region	2	54	N/A	INTRINSIC
Pfam:DHC_N1	379	936	8.4e-159	PFAM
low complexity region	1069	1080	N/A	INTRINSIC
low complexity region	1224	1237	N/A	INTRINSIC
Pfam:DHC_N2	1509	1917	1.6e-134	PFAM
AAA	2082	2226	1.38e-1	SMART
AAA	2363	2516	2.04e-1	SMART
AAA	2689	2837	8.15e-2	SMART
Pfam:AAA_8	3022	3294	4e-72	PFAM
Pfam:MT	3306	3656	3.6e-48	PFAM
Pfam:AAA_9	3676	3901	6.7e-85	PFAM
Pfam:Dynein_heavy	4039	4728	8.4e-250	PFAM

Meta Mutation Damage Score

0.9712

Coding Region Coverage

1x: 99.2%
3x: 98.6%
10x: 97.3%
20x: 95.2%

Validation Efficiency

98% (50/51)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a heavy chain of an axonemal dynein involved in sperm and respiratory cilia motility. Axonemal dyneins generate force through hydrolysis of ATP and binding to microtubules. [provided by RefSeq, Jan 2012]

Allele List at MGI

Other mutations in this stock

Total: 51 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Adam12	T	C	7: 134,172,865	D5G	probably damaging	Het
Adam19	A	T	11: 46,137,610	D690V	probably benign	Het
Ankib1	G	T	5: 3,734,097	P293Q	probably damaging	Het
Arhgap19	T	A	19: 41,774,079	E461V	probably damaging	Het
Bckdk	C	A	7: 127,905,418	R105S	probably damaging	Het
Bub1b	T	A	2: 118,615,455	N319K	possibly damaging	Het
Ccdc40	T	C	11: 119,264,426	V1164A	probably benign	Het
Cfhr1	C	A	1: 139,557,634		probably null	Het
Colq	A	T	14: 31,549,453		probably benign	Het
Daam1	C	A	12: 71,971,166	D716E	probably damaging	Het
Dnah17	T	C	11: 118,082,916	S1935G	probably benign	Het
Faap24	A	T	7: 35,393,012	V160D	possibly damaging	Het
Gpc1	C	A	1: 92,857,582	C414*	probably null	Het
Igkv9-120	G	A	6: 68,050,001	A7T	probably benign	Het
Kcnu1	T	A	8: 25,886,770	C391S	probably null	Het
Lrba	T	G	3: 86,375,953	L1858R	probably damaging	Het
Lrp10	A	T	14: 54,469,266	N520I	possibly damaging	Het
March6	A	G	15: 31,462,014	V856A	probably benign	Het
Mfsd1	T	C	3: 67,582,953	S46P	probably benign	Het
Mme	T	A	3: 63,343,540	V334E	probably damaging	Het
Mroh2b	G	A	15: 4,952,246	W1513*	probably null	Het
Nuf2	T	A	1: 169,525,376	N20I	probably damaging	Het
Obsl1	T	C	1: 75,498,246	T642A	probably benign	Het
Olfm1	C	T	2: 28,208,088	T54I	probably damaging	Het
Olfr803	C	T	10: 129,691,961	V27I	probably benign	Het
Olfr95	G	A	17: 37,211,800	R18C	possibly damaging	Het
Osbpl7	T	C	11: 97,056,053	V223A	probably damaging	Het
Patj	A	G	4: 98,469,600	Y701C	probably damaging	Het
Pkdrej	T	A	15: 85,821,077	K219N	probably damaging	Het
Scn2a	T	G	2: 65,713,771	V832G	probably damaging	Het
Secisbp2l	C	T	2: 125,740,737	G933D	possibly damaging	Het
Slc25a25	G	T	2: 32,420,380	N122K	probably benign	Het
Slk	T	G	19: 47,619,809	D400E	possibly damaging	Het
Spon1	T	A	7: 114,016,791	V297E	possibly damaging	Het
Spon1	T	C	7: 113,766,384	L19P	probably damaging	Het
Supt16	A	G	14: 52,180,139	L306P	probably damaging	Het
Syne1	C	T	10: 5,052,267		probably benign	Het
Tas2r136	A	T	6: 132,777,237	F309Y	probably damaging	Het
Terb1	T	C	8: 104,496,834	D114G	probably damaging	Het
Tlr5	T	C	1: 182,974,439	I436T	probably benign	Het
Tpcn2	T	C	7: 145,255,523	H682R	probably damaging	Het
Tpi1	T	A	6: 124,812,791	S130C	probably damaging	Het
Ttn	G	A	2: 76,754,006	H22253Y	probably damaging	Het
Uggt2	A	T	14: 119,057,672	V38E	probably benign	Het
Vmn1r158	A	C	7: 22,790,214	L190W	probably damaging	Het
Vwa5b2	A	G	16: 20,598,326		probably benign	Het
Wnt2	T	C	6: 18,023,168	I161V	probably benign	Het
Zdhhc25	C	T	15: 88,601,023	S187L	probably benign	Het
Zfhx4	G	A	3: 5,243,165	E484K	possibly damaging	Het
Zkscan1	T	C	5: 138,101,441	S476P	probably damaging	Het
Zmynd8	A	G	2: 165,805,198	Y945H	probably damaging	Het

Other mutations in Dnah8

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00498:Dnah8	APN	17	30,677,176 (GRCm38)	missense	probably benign	0.06
IGL00508:Dnah8	APN	17	30,855,930 (GRCm38)	missense	probably damaging	1.00
IGL00547:Dnah8	APN	17	30,815,703 (GRCm38)	nonsense	probably null
IGL00551:Dnah8	APN	17	30,663,478 (GRCm38)	nonsense	probably null
IGL00732:Dnah8	APN	17	30,656,641 (GRCm38)	missense	probably damaging	1.00
IGL00775:Dnah8	APN	17	30,767,906 (GRCm38)	nonsense	probably null
IGL00840:Dnah8	APN	17	30,790,941 (GRCm38)	missense	probably damaging	1.00
IGL00845:Dnah8	APN	17	30,819,276 (GRCm38)	critical splice donor site	probably null
IGL00953:Dnah8	APN	17	30,706,457 (GRCm38)	nonsense	probably null
IGL00976:Dnah8	APN	17	30,851,710 (GRCm38)	missense	probably damaging	0.98
IGL01395:Dnah8	APN	17	30,636,005 (GRCm38)	missense	probably benign	0.06
IGL01467:Dnah8	APN	17	30,779,916 (GRCm38)	missense	probably damaging	1.00
IGL01469:Dnah8	APN	17	30,683,714 (GRCm38)	splice site	probably benign
IGL01515:Dnah8	APN	17	30,648,485 (GRCm38)	missense	probably benign
IGL01723:Dnah8	APN	17	30,708,471 (GRCm38)	missense	probably damaging	1.00
IGL01837:Dnah8	APN	17	30,751,591 (GRCm38)	critical splice donor site	probably null
IGL01921:Dnah8	APN	17	30,736,141 (GRCm38)	missense	probably benign
IGL01958:Dnah8	APN	17	30,855,895 (GRCm38)	splice site	probably benign
IGL01968:Dnah8	APN	17	30,656,598 (GRCm38)	nonsense	probably null
IGL02093:Dnah8	APN	17	30,717,880 (GRCm38)	missense	probably damaging	0.99
IGL02151:Dnah8	APN	17	30,648,417 (GRCm38)	missense	possibly damaging	0.50
IGL02182:Dnah8	APN	17	30,794,763 (GRCm38)	missense	possibly damaging	0.45
IGL02233:Dnah8	APN	17	30,706,513 (GRCm38)	critical splice donor site	probably null
IGL02236:Dnah8	APN	17	30,649,773 (GRCm38)	nonsense	probably null
IGL02259:Dnah8	APN	17	30,759,614 (GRCm38)	missense	probably benign
IGL02263:Dnah8	APN	17	30,729,165 (GRCm38)	missense	probably benign	0.00
IGL02303:Dnah8	APN	17	30,713,047 (GRCm38)	missense	probably benign	0.03
IGL02341:Dnah8	APN	17	30,747,257 (GRCm38)	missense	probably damaging	1.00
IGL02351:Dnah8	APN	17	30,767,811 (GRCm38)	missense	probably damaging	1.00
IGL02358:Dnah8	APN	17	30,767,811 (GRCm38)	missense	probably damaging	1.00
IGL02377:Dnah8	APN	17	30,794,796 (GRCm38)	missense	probably damaging	0.98
IGL02390:Dnah8	APN	17	30,830,845 (GRCm38)	missense	probably benign	0.01
IGL02392:Dnah8	APN	17	30,818,051 (GRCm38)	splice site	probably benign
IGL02414:Dnah8	APN	17	30,700,413 (GRCm38)	missense	probably benign
IGL02455:Dnah8	APN	17	30,672,334 (GRCm38)	missense	probably damaging	0.99
IGL02817:Dnah8	APN	17	30,668,295 (GRCm38)	missense	probably benign
IGL02831:Dnah8	APN	17	30,712,276 (GRCm38)	missense	probably benign	0.23
IGL02863:Dnah8	APN	17	30,769,697 (GRCm38)	missense	probably damaging	1.00
IGL02894:Dnah8	APN	17	30,721,110 (GRCm38)	nonsense	probably null
IGL02954:Dnah8	APN	17	30,704,835 (GRCm38)	missense	probably benign	0.30
IGL02964:Dnah8	APN	17	30,746,761 (GRCm38)	missense	probably damaging	1.00
IGL03080:Dnah8	APN	17	30,719,006 (GRCm38)	missense	probably benign	0.01
IGL03081:Dnah8	APN	17	30,686,373 (GRCm38)	splice site	probably benign
IGL03086:Dnah8	APN	17	30,742,780 (GRCm38)	missense	probably damaging	1.00
IGL03087:Dnah8	APN	17	30,784,144 (GRCm38)	missense	probably benign
IGL03176:Dnah8	APN	17	30,694,037 (GRCm38)	missense	probably benign
IGL03191:Dnah8	APN	17	30,726,830 (GRCm38)	missense	probably damaging	0.99
IGL03210:Dnah8	APN	17	30,815,665 (GRCm38)	missense	probably damaging	0.96
IGL03252:Dnah8	APN	17	30,673,920 (GRCm38)	splice site	probably null
IGL03255:Dnah8	APN	17	30,741,381 (GRCm38)	missense	probably damaging	1.00
IGL03288:Dnah8	APN	17	30,672,349 (GRCm38)	missense	probably benign
IGL03348:Dnah8	APN	17	30,746,986 (GRCm38)	missense	probably damaging	0.99
Alternator	UTSW	17	30,765,635 (GRCm38)	missense	probably benign
armature	UTSW	17	30,708,390 (GRCm38)	missense	probably benign	0.02
Brush	UTSW	17	30,746,990 (GRCm38)	missense	probably damaging	1.00
Dynos	UTSW	17	30,715,509 (GRCm38)	missense	possibly damaging	0.84
joule	UTSW	17	30,713,098 (GRCm38)	critical splice donor site	probably null
solenoid	UTSW	17	30,741,178 (GRCm38)	missense	probably damaging	1.00
FR4340:Dnah8	UTSW	17	30,635,463 (GRCm38)	small deletion	probably benign
FR4737:Dnah8	UTSW	17	30,635,477 (GRCm38)	small deletion	probably benign
FR4737:Dnah8	UTSW	17	30,635,465 (GRCm38)	small deletion	probably benign
I2288:Dnah8	UTSW	17	30,663,454 (GRCm38)	missense	probably benign
P0029:Dnah8	UTSW	17	30,765,720 (GRCm38)	missense	probably damaging	1.00
PIT4812001:Dnah8	UTSW	17	30,708,445 (GRCm38)	missense	probably benign	0.04
R0016:Dnah8	UTSW	17	30,663,316 (GRCm38)	missense	probably benign
R0035:Dnah8	UTSW	17	30,683,621 (GRCm38)	splice site	probably benign
R0035:Dnah8	UTSW	17	30,683,621 (GRCm38)	splice site	probably benign
R0062:Dnah8	UTSW	17	30,765,711 (GRCm38)	missense	probably damaging	1.00
R0062:Dnah8	UTSW	17	30,765,711 (GRCm38)	missense	probably damaging	1.00
R0087:Dnah8	UTSW	17	30,755,119 (GRCm38)	missense	probably damaging	1.00
R0090:Dnah8	UTSW	17	30,784,090 (GRCm38)	missense	probably benign	0.20
R0119:Dnah8	UTSW	17	30,715,509 (GRCm38)	missense	possibly damaging	0.84
R0164:Dnah8	UTSW	17	30,748,665 (GRCm38)	missense	probably benign
R0164:Dnah8	UTSW	17	30,748,665 (GRCm38)	missense	probably benign
R0184:Dnah8	UTSW	17	30,683,683 (GRCm38)	missense	probably benign	0.04
R0240:Dnah8	UTSW	17	30,765,679 (GRCm38)	missense	probably damaging	0.98
R0240:Dnah8	UTSW	17	30,765,679 (GRCm38)	missense	probably damaging	0.98
R0241:Dnah8	UTSW	17	30,765,679 (GRCm38)	missense	probably damaging	0.98
R0241:Dnah8	UTSW	17	30,765,679 (GRCm38)	missense	probably damaging	0.98
R0265:Dnah8	UTSW	17	30,690,271 (GRCm38)	missense	probably benign
R0268:Dnah8	UTSW	17	30,769,707 (GRCm38)	missense	probably damaging	1.00
R0282:Dnah8	UTSW	17	30,736,156 (GRCm38)	missense	probably damaging	1.00
R0299:Dnah8	UTSW	17	30,715,509 (GRCm38)	missense	possibly damaging	0.84
R0334:Dnah8	UTSW	17	30,871,351 (GRCm38)	missense	probably damaging	0.99
R0393:Dnah8	UTSW	17	30,708,390 (GRCm38)	missense	probably benign	0.02
R0423:Dnah8	UTSW	17	30,701,981 (GRCm38)	missense	probably benign
R0470:Dnah8	UTSW	17	30,708,540 (GRCm38)	splice site	probably benign
R0477:Dnah8	UTSW	17	30,755,080 (GRCm38)	missense	probably damaging	1.00
R0490:Dnah8	UTSW	17	30,700,419 (GRCm38)	missense	probably benign
R0499:Dnah8	UTSW	17	30,715,509 (GRCm38)	missense	possibly damaging	0.84
R0582:Dnah8	UTSW	17	30,718,961 (GRCm38)	missense	probably benign	0.01
R0601:Dnah8	UTSW	17	30,708,358 (GRCm38)	missense	probably benign	0.06
R0646:Dnah8	UTSW	17	30,684,173 (GRCm38)	missense	probably damaging	0.97
R0665:Dnah8	UTSW	17	30,736,155 (GRCm38)	missense	probably damaging	0.99
R0800:Dnah8	UTSW	17	30,704,662 (GRCm38)	missense	probably benign
R0843:Dnah8	UTSW	17	30,813,095 (GRCm38)	missense	probably damaging	1.00
R0940:Dnah8	UTSW	17	30,803,243 (GRCm38)	missense	probably damaging	1.00
R0964:Dnah8	UTSW	17	30,673,920 (GRCm38)	splice site	probably null
R1102:Dnah8	UTSW	17	30,854,764 (GRCm38)	splice site	probably null
R1137:Dnah8	UTSW	17	30,855,936 (GRCm38)	missense	probably damaging	1.00
R1342:Dnah8	UTSW	17	30,721,000 (GRCm38)	missense	probably damaging	0.99
R1375:Dnah8	UTSW	17	30,737,295 (GRCm38)	missense	probably damaging	1.00
R1377:Dnah8	UTSW	17	30,840,622 (GRCm38)	nonsense	probably null
R1464:Dnah8	UTSW	17	30,695,173 (GRCm38)	missense	possibly damaging	0.81
R1464:Dnah8	UTSW	17	30,695,173 (GRCm38)	missense	possibly damaging	0.81
R1470:Dnah8	UTSW	17	30,747,277 (GRCm38)	nonsense	probably null
R1470:Dnah8	UTSW	17	30,747,277 (GRCm38)	nonsense	probably null
R1497:Dnah8	UTSW	17	30,752,075 (GRCm38)	missense	probably damaging	1.00
R1513:Dnah8	UTSW	17	30,673,888 (GRCm38)	missense	probably benign
R1541:Dnah8	UTSW	17	30,747,247 (GRCm38)	missense	probably damaging	1.00
R1563:Dnah8	UTSW	17	30,635,664 (GRCm38)	missense	probably benign	0.07
R1634:Dnah8	UTSW	17	30,713,098 (GRCm38)	critical splice donor site	probably null
R1670:Dnah8	UTSW	17	30,725,124 (GRCm38)	missense	probably damaging	1.00
R1710:Dnah8	UTSW	17	30,854,940 (GRCm38)	missense	probably damaging	1.00
R1743:Dnah8	UTSW	17	30,769,651 (GRCm38)	missense	probably benign	0.28
R1761:Dnah8	UTSW	17	30,779,916 (GRCm38)	missense	probably damaging	1.00
R1785:Dnah8	UTSW	17	30,722,937 (GRCm38)	missense	probably damaging	0.98
R1804:Dnah8	UTSW	17	30,708,407 (GRCm38)	missense	probably benign	0.00
R1808:Dnah8	UTSW	17	30,684,186 (GRCm38)	missense	probably damaging	1.00
R1824:Dnah8	UTSW	17	30,731,180 (GRCm38)	missense	possibly damaging	0.67
R1836:Dnah8	UTSW	17	30,874,927 (GRCm38)	missense	possibly damaging	0.94
R1935:Dnah8	UTSW	17	30,635,505 (GRCm38)	missense	unknown
R1935:Dnah8	UTSW	17	30,726,896 (GRCm38)	splice site	probably benign
R1940:Dnah8	UTSW	17	30,731,207 (GRCm38)	missense	probably damaging	1.00
R1946:Dnah8	UTSW	17	30,712,385 (GRCm38)	missense	probably benign	0.00
R2025:Dnah8	UTSW	17	30,731,159 (GRCm38)	missense	probably damaging	0.99
R2038:Dnah8	UTSW	17	30,758,281 (GRCm38)	missense	probably damaging	1.00
R2042:Dnah8	UTSW	17	30,635,658 (GRCm38)	missense	probably benign	0.01
R2148:Dnah8	UTSW	17	30,737,258 (GRCm38)	missense	probably damaging	1.00
R2177:Dnah8	UTSW	17	30,653,393 (GRCm38)	missense	probably benign
R2180:Dnah8	UTSW	17	30,840,647 (GRCm38)	missense	probably benign	0.00
R2262:Dnah8	UTSW	17	30,673,835 (GRCm38)	missense	probably damaging	1.00
R2263:Dnah8	UTSW	17	30,673,835 (GRCm38)	missense	probably damaging	1.00
R2328:Dnah8	UTSW	17	30,794,744 (GRCm38)	missense	probably damaging	1.00
R2357:Dnah8	UTSW	17	30,771,872 (GRCm38)	missense	probably benign
R2357:Dnah8	UTSW	17	30,874,935 (GRCm38)	missense	probably benign	0.00
R2360:Dnah8	UTSW	17	30,677,204 (GRCm38)	missense	probably benign	0.22
R2496:Dnah8	UTSW	17	30,851,731 (GRCm38)	missense	probably damaging	1.00
R2497:Dnah8	UTSW	17	30,741,365 (GRCm38)	nonsense	probably null
R2509:Dnah8	UTSW	17	30,775,045 (GRCm38)	missense	probably benign	0.02
R3114:Dnah8	UTSW	17	30,833,568 (GRCm38)	missense	probably benign	0.04
R3708:Dnah8	UTSW	17	30,739,657 (GRCm38)	missense	probably damaging	0.98
R3720:Dnah8	UTSW	17	30,854,898 (GRCm38)	missense	probably damaging	1.00
R3722:Dnah8	UTSW	17	30,854,898 (GRCm38)	missense	probably damaging	1.00
R3727:Dnah8	UTSW	17	30,739,648 (GRCm38)	nonsense	probably null
R3747:Dnah8	UTSW	17	30,784,174 (GRCm38)	nonsense	probably null
R3748:Dnah8	UTSW	17	30,784,174 (GRCm38)	nonsense	probably null
R3787:Dnah8	UTSW	17	30,755,041 (GRCm38)	missense	probably damaging	1.00
R3790:Dnah8	UTSW	17	30,854,898 (GRCm38)	missense	probably damaging	1.00
R3804:Dnah8	UTSW	17	30,670,647 (GRCm38)	missense	probably benign	0.00
R3857:Dnah8	UTSW	17	30,663,422 (GRCm38)	missense	probably damaging	0.96
R3898:Dnah8	UTSW	17	30,854,898 (GRCm38)	missense	probably damaging	1.00
R3899:Dnah8	UTSW	17	30,854,898 (GRCm38)	missense	probably damaging	1.00
R3938:Dnah8	UTSW	17	30,854,937 (GRCm38)	missense	probably damaging	1.00
R3943:Dnah8	UTSW	17	30,694,065 (GRCm38)	splice site	probably benign
R4091:Dnah8	UTSW	17	30,769,839 (GRCm38)	missense	probably damaging	1.00
R4291:Dnah8	UTSW	17	30,748,559 (GRCm38)	missense	probably benign
R4326:Dnah8	UTSW	17	30,752,092 (GRCm38)	missense	probably benign	0.04
R4346:Dnah8	UTSW	17	30,725,098 (GRCm38)	missense	possibly damaging	0.92
R4429:Dnah8	UTSW	17	30,752,146 (GRCm38)	missense	probably damaging	1.00
R4457:Dnah8	UTSW	17	30,813,151 (GRCm38)	missense	probably benign
R4475:Dnah8	UTSW	17	30,656,985 (GRCm38)	missense	probably benign	0.12
R4565:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R4566:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R4568:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R4573:Dnah8	UTSW	17	30,700,406 (GRCm38)	missense	probably benign	0.00
R4580:Dnah8	UTSW	17	30,662,052 (GRCm38)	missense	probably benign	0.00
R4585:Dnah8	UTSW	17	30,751,567 (GRCm38)	missense	probably benign	0.01
R4611:Dnah8	UTSW	17	30,684,237 (GRCm38)	missense	probably damaging	1.00
R4720:Dnah8	UTSW	17	30,683,634 (GRCm38)	missense	probably benign	0.08
R4721:Dnah8	UTSW	17	30,725,166 (GRCm38)	missense	probably damaging	1.00
R4727:Dnah8	UTSW	17	30,851,747 (GRCm38)	missense	probably damaging	1.00
R4731:Dnah8	UTSW	17	30,775,061 (GRCm38)	missense	probably null	0.02
R4732:Dnah8	UTSW	17	30,775,061 (GRCm38)	missense	probably null	0.02
R4733:Dnah8	UTSW	17	30,775,061 (GRCm38)	missense	probably null	0.02
R4798:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R4814:Dnah8	UTSW	17	30,767,924 (GRCm38)	missense	probably damaging	1.00
R4892:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R4894:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R4900:Dnah8	UTSW	17	30,746,975 (GRCm38)	missense	probably damaging	1.00
R4901:Dnah8	UTSW	17	30,840,714 (GRCm38)	critical splice donor site	probably null
R4913:Dnah8	UTSW	17	30,819,139 (GRCm38)	missense	probably damaging	0.99
R4931:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R4932:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R4933:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R4942:Dnah8	UTSW	17	30,729,142 (GRCm38)	missense	probably benign
R4969:Dnah8	UTSW	17	30,723,014 (GRCm38)	missense	probably damaging	1.00
R4975:Dnah8	UTSW	17	30,656,985 (GRCm38)	missense	probably benign	0.12
R4977:Dnah8	UTSW	17	30,663,301 (GRCm38)	missense	probably benign	0.00
R5001:Dnah8	UTSW	17	30,787,185 (GRCm38)	missense	probably damaging	1.00
R5011:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R5013:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R5014:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R5024:Dnah8	UTSW	17	30,736,096 (GRCm38)	missense	probably damaging	1.00
R5075:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R5075:Dnah8	UTSW	17	30,800,531 (GRCm38)	missense	probably damaging	1.00
R5075:Dnah8	UTSW	17	30,739,757 (GRCm38)	critical splice donor site	probably null
R5112:Dnah8	UTSW	17	30,731,038 (GRCm38)	missense	probably benign	0.02
R5121:Dnah8	UTSW	17	30,810,353 (GRCm38)	missense	probably benign	0.14
R5138:Dnah8	UTSW	17	30,765,597 (GRCm38)	missense	probably damaging	0.99
R5151:Dnah8	UTSW	17	30,712,295 (GRCm38)	missense	probably benign	0.06
R5191:Dnah8	UTSW	17	30,746,765 (GRCm38)	missense	probably damaging	1.00
R5238:Dnah8	UTSW	17	30,790,917 (GRCm38)	missense	probably damaging	1.00
R5260:Dnah8	UTSW	17	30,700,419 (GRCm38)	missense	probably benign
R5358:Dnah8	UTSW	17	30,746,954 (GRCm38)	missense	probably damaging	1.00
R5403:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R5404:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R5482:Dnah8	UTSW	17	30,800,547 (GRCm38)	missense	probably damaging	0.96
R5489:Dnah8	UTSW	17	30,790,956 (GRCm38)	missense	probably damaging	1.00
R5513:Dnah8	UTSW	17	30,752,916 (GRCm38)	missense	probably damaging	0.99
R5635:Dnah8	UTSW	17	30,706,386 (GRCm38)	missense	probably benign	0.00
R5640:Dnah8	UTSW	17	30,803,108 (GRCm38)	missense	probably damaging	1.00
R5649:Dnah8	UTSW	17	30,800,587 (GRCm38)	missense	probably benign	0.13
R5662:Dnah8	UTSW	17	30,737,333 (GRCm38)	missense	probably damaging	1.00
R5673:Dnah8	UTSW	17	30,803,261 (GRCm38)	missense	probably damaging	1.00
R5677:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R5699:Dnah8	UTSW	17	30,810,324 (GRCm38)	missense	probably benign	0.22
R5737:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R5738:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R5739:Dnah8	UTSW	17	30,719,007 (GRCm38)	missense	probably benign	0.00
R5766:Dnah8	UTSW	17	30,690,261 (GRCm38)	missense	probably benign	0.01
R5790:Dnah8	UTSW	17	30,875,004 (GRCm38)	missense	probably damaging	0.98
R5848:Dnah8	UTSW	17	30,728,191 (GRCm38)	missense	possibly damaging	0.69
R5854:Dnah8	UTSW	17	30,794,763 (GRCm38)	missense	possibly damaging	0.45
R5885:Dnah8	UTSW	17	30,794,717 (GRCm38)	missense	probably damaging	1.00
R5886:Dnah8	UTSW	17	30,794,717 (GRCm38)	missense	probably damaging	1.00
R5887:Dnah8	UTSW	17	30,794,717 (GRCm38)	missense	probably damaging	1.00
R5899:Dnah8	UTSW	17	30,656,685 (GRCm38)	missense	probably benign	0.32
R5979:Dnah8	UTSW	17	30,815,664 (GRCm38)	nonsense	probably null
R5986:Dnah8	UTSW	17	30,851,630 (GRCm38)	missense	possibly damaging	0.83
R5999:Dnah8	UTSW	17	30,663,305 (GRCm38)	missense	probably benign	0.32
R6042:Dnah8	UTSW	17	30,747,265 (GRCm38)	missense	probably damaging	1.00
R6175:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R6181:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R6237:Dnah8	UTSW	17	30,747,854 (GRCm38)	nonsense	probably null
R6239:Dnah8	UTSW	17	30,810,359 (GRCm38)	missense	probably damaging	0.99
R6337:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R6365:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R6416:Dnah8	UTSW	17	30,765,635 (GRCm38)	missense	probably benign
R6443:Dnah8	UTSW	17	30,771,885 (GRCm38)	missense	probably benign	0.10
R6478:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R6479:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R6480:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R6481:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R6533:Dnah8	UTSW	17	30,746,990 (GRCm38)	missense	probably damaging	1.00
R6606:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R6608:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R6610:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R6675:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R6723:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R6724:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R6754:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R6755:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R6759:Dnah8	UTSW	17	30,663,292 (GRCm38)	splice site	probably null
R6765:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R6766:Dnah8	UTSW	17	30,748,568 (GRCm38)	missense	probably benign	0.00
R6778:Dnah8	UTSW	17	30,635,666 (GRCm38)	missense	probably benign	0.00
R6781:Dnah8	UTSW	17	30,765,724 (GRCm38)	frame shift	probably null
R6788:Dnah8	UTSW	17	30,648,465 (GRCm38)	missense	probably benign	0.14
R6814:Dnah8	UTSW	17	30,762,679 (GRCm38)	missense	probably damaging	1.00
R6825:Dnah8	UTSW	17	30,741,173 (GRCm38)	missense	probably damaging	1.00
R6838:Dnah8	UTSW	17	30,710,551 (GRCm38)	missense	probably damaging	1.00
R6872:Dnah8	UTSW	17	30,762,679 (GRCm38)	missense	probably damaging	1.00
R6877:Dnah8	UTSW	17	30,746,959 (GRCm38)	missense	probably damaging	1.00
R6944:Dnah8	UTSW	17	30,794,659 (GRCm38)	missense	probably benign	0.09
R6982:Dnah8	UTSW	17	30,767,925 (GRCm38)	missense	probably benign	0.03
R6984:Dnah8	UTSW	17	30,739,738 (GRCm38)	missense	probably damaging	1.00
R6987:Dnah8	UTSW	17	30,662,091 (GRCm38)	missense	possibly damaging	0.95
R6988:Dnah8	UTSW	17	30,643,275 (GRCm38)	missense	probably damaging	1.00
R7099:Dnah8	UTSW	17	30,704,724 (GRCm38)	missense	possibly damaging	0.93
R7106:Dnah8	UTSW	17	30,741,178 (GRCm38)	missense	probably damaging	1.00
R7112:Dnah8	UTSW	17	30,871,392 (GRCm38)	missense	possibly damaging	0.79
R7146:Dnah8	UTSW	17	30,769,644 (GRCm38)	missense	possibly damaging	0.90
R7146:Dnah8	UTSW	17	30,644,617 (GRCm38)	missense	probably benign	0.01
R7309:Dnah8	UTSW	17	30,875,014 (GRCm38)	missense	probably damaging	1.00
R7324:Dnah8	UTSW	17	30,784,125 (GRCm38)	missense	probably benign	0.01
R7373:Dnah8	UTSW	17	30,767,965 (GRCm38)	critical splice donor site	probably null
R7423:Dnah8	UTSW	17	30,704,769 (GRCm38)	missense	possibly damaging	0.86
R7430:Dnah8	UTSW	17	30,706,389 (GRCm38)	missense	probably damaging	0.98
R7450:Dnah8	UTSW	17	30,787,191 (GRCm38)	missense	probably damaging	0.99
R7580:Dnah8	UTSW	17	30,775,103 (GRCm38)	missense	probably damaging	0.98
R7604:Dnah8	UTSW	17	30,813,095 (GRCm38)	missense	probably damaging	1.00
R7635:Dnah8	UTSW	17	30,785,107 (GRCm38)	missense	probably damaging	1.00
R7646:Dnah8	UTSW	17	30,649,677 (GRCm38)	missense	probably benign	0.00
R7685:Dnah8	UTSW	17	30,657,973 (GRCm38)	missense	probably damaging	1.00
R7793:Dnah8	UTSW	17	30,855,944 (GRCm38)	missense	probably benign	0.20
R7827:Dnah8	UTSW	17	30,760,867 (GRCm38)	frame shift	probably null
R7866:Dnah8	UTSW	17	30,874,927 (GRCm38)	missense	possibly damaging	0.94
R7877:Dnah8	UTSW	17	30,663,374 (GRCm38)	missense	probably benign
R7891:Dnah8	UTSW	17	30,712,289 (GRCm38)	missense	probably benign	0.09
R7977:Dnah8	UTSW	17	30,744,524 (GRCm38)	missense	probably damaging	1.00
R7987:Dnah8	UTSW	17	30,744,524 (GRCm38)	missense	probably damaging	1.00
R8025:Dnah8	UTSW	17	30,741,337 (GRCm38)	nonsense	probably null
R8076:Dnah8	UTSW	17	30,784,153 (GRCm38)	missense	possibly damaging	0.94
R8170:Dnah8	UTSW	17	30,673,823 (GRCm38)	missense	probably damaging	1.00
R8199:Dnah8	UTSW	17	30,871,419 (GRCm38)	missense	probably benign	0.06
R8253:Dnah8	UTSW	17	30,760,867 (GRCm38)	frame shift	probably null
R8270:Dnah8	UTSW	17	30,840,713 (GRCm38)	missense	probably damaging	1.00
R8291:Dnah8	UTSW	17	30,765,727 (GRCm38)	missense	probably damaging	1.00
R8334:Dnah8	UTSW	17	30,769,831 (GRCm38)	missense	probably benign	0.12
R8348:Dnah8	UTSW	17	30,673,840 (GRCm38)	missense	probably benign
R8348:Dnah8	UTSW	17	30,736,147 (GRCm38)	missense	probably damaging	0.96
R8354:Dnah8	UTSW	17	30,643,260 (GRCm38)	missense	probably benign	0.17
R8355:Dnah8	UTSW	17	30,695,178 (GRCm38)	missense	possibly damaging	0.89
R8439:Dnah8	UTSW	17	30,760,867 (GRCm38)	frame shift	probably null
R8448:Dnah8	UTSW	17	30,673,840 (GRCm38)	missense	probably benign
R8459:Dnah8	UTSW	17	30,725,247 (GRCm38)	critical splice donor site	probably null
R8462:Dnah8	UTSW	17	30,656,629 (GRCm38)	missense	probably damaging	1.00
R8506:Dnah8	UTSW	17	30,721,134 (GRCm38)	missense	probably benign
R8524:Dnah8	UTSW	17	30,715,498 (GRCm38)	missense	possibly damaging	0.95
R8555:Dnah8	UTSW	17	30,721,110 (GRCm38)	nonsense	probably null
R8698:Dnah8	UTSW	17	30,875,035 (GRCm38)	missense	probably damaging	1.00
R8719:Dnah8	UTSW	17	30,741,315 (GRCm38)	missense	probably damaging	0.97
R8778:Dnah8	UTSW	17	30,760,867 (GRCm38)	frame shift	probably null
R8781:Dnah8	UTSW	17	30,725,104 (GRCm38)	missense	probably damaging	1.00
R8821:Dnah8	UTSW	17	30,794,738 (GRCm38)	missense	probably damaging	1.00
R8864:Dnah8	UTSW	17	30,762,642 (GRCm38)	missense	possibly damaging	0.95
R8885:Dnah8	UTSW	17	30,708,312 (GRCm38)	missense	possibly damaging	0.83
R8983:Dnah8	UTSW	17	30,851,654 (GRCm38)	missense	probably damaging	0.98
R8994:Dnah8	UTSW	17	30,790,833 (GRCm38)	missense	probably benign	0.05
R9031:Dnah8	UTSW	17	30,737,427 (GRCm38)	missense	probably damaging	1.00
R9068:Dnah8	UTSW	17	30,756,755 (GRCm38)	missense	possibly damaging	0.63
R9225:Dnah8	UTSW	17	30,635,673 (GRCm38)	missense	probably benign	0.01
R9280:Dnah8	UTSW	17	30,785,097 (GRCm38)	missense	possibly damaging	0.52
R9291:Dnah8	UTSW	17	30,725,125 (GRCm38)	missense	probably damaging	1.00
R9314:Dnah8	UTSW	17	30,771,883 (GRCm38)	missense	probably benign
R9347:Dnah8	UTSW	17	30,708,359 (GRCm38)	missense	probably benign	0.00
R9393:Dnah8	UTSW	17	30,653,387 (GRCm38)	missense	possibly damaging	0.53
R9415:Dnah8	UTSW	17	30,810,323 (GRCm38)	missense	probably benign	0.02
R9458:Dnah8	UTSW	17	30,830,803 (GRCm38)	missense	probably damaging	1.00
R9465:Dnah8	UTSW	17	30,760,867 (GRCm38)	frame shift	probably null
R9518:Dnah8	UTSW	17	30,760,867 (GRCm38)	frame shift	probably null
R9524:Dnah8	UTSW	17	30,760,867 (GRCm38)	frame shift	probably null
R9564:Dnah8	UTSW	17	30,713,047 (GRCm38)	missense	probably benign	0.07
R9587:Dnah8	UTSW	17	30,760,867 (GRCm38)	frame shift	probably null
R9599:Dnah8	UTSW	17	30,760,867 (GRCm38)	frame shift	probably null
R9641:Dnah8	UTSW	17	30,713,055 (GRCm38)	missense	probably benign	0.13
R9674:Dnah8	UTSW	17	30,779,138 (GRCm38)	missense	possibly damaging	0.84
R9679:Dnah8	UTSW	17	30,818,141 (GRCm38)	missense	probably benign
R9789:Dnah8	UTSW	17	30,761,130 (GRCm38)	critical splice donor site	probably null
RF027:Dnah8	UTSW	17	30,635,476 (GRCm38)	frame shift	probably null
X0001:Dnah8	UTSW	17	30,748,680 (GRCm38)	missense	probably damaging	1.00
X0013:Dnah8	UTSW	17	30,819,186 (GRCm38)	missense	possibly damaging	0.71
Z1176:Dnah8	UTSW	17	30,648,540 (GRCm38)	missense	probably benign
Z1177:Dnah8	UTSW	17	30,713,095 (GRCm38)	missense	probably null	1.00
Z1177:Dnah8	UTSW	17	30,694,033 (GRCm38)	missense	probably benign

Predicted Primers

PCR Primer
(F):5'- AACATGTCCCTGCTGCAGAG -3'
(R):5'- TCCTGGTGAACGGTGAACTG -3'

Sequencing Primer
(F):5'- CCCTGCTGCAGAGCTTGAAAATG -3'
(R):5'- CGGTGAACTGAAACATCGC -3'

Posted On

2015-04-17