Incidental Mutation 'R0383:St18'
| ID |
31042 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
St18
|
| Ensembl Gene |
ENSMUSG00000033740 |
| Gene Name |
suppression of tumorigenicity 18 |
| Synonyms |
Nzf3, Myt3 |
| MMRRC Submission |
038589-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R0383 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
1 |
| Chromosomal Location |
6557455-6931164 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 6873248 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Phenylalanine to Isoleucine
at position 328
(F328I)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000131417
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000043578]
[ENSMUST00000131494]
[ENSMUST00000139838]
[ENSMUST00000140079]
[ENSMUST00000150761]
[ENSMUST00000151281]
[ENSMUST00000163727]
|
| AlphaFold |
Q80TY4 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000043578
AA Change: F328I
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000042056
Gene: ENSMUSG00000033740
AA Change: F328I
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
188 |
198 |
N/A |
INTRINSIC |
|
Pfam:zf-C2HC
|
365 |
392 |
7.8e-15 |
PFAM |
|
Pfam:zf-C2HC
|
409 |
437 |
4.2e-17 |
PFAM |
|
Pfam:MYT1
|
476 |
713 |
1.3e-75 |
PFAM |
|
Pfam:zf-C2HC
|
721 |
749 |
4e-19 |
PFAM |
|
Pfam:zf-C2HC
|
765 |
793 |
1.7e-19 |
PFAM |
|
Pfam:zf-C2HC
|
813 |
841 |
1.1e-17 |
PFAM |
|
Pfam:zf-C2HC
|
866 |
893 |
9.1e-15 |
PFAM |
|
coiled coil region
|
918 |
987 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000131494
AA Change: F328I
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000117789
Gene: ENSMUSG00000033740
AA Change: F328I
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
188 |
198 |
N/A |
INTRINSIC |
|
Pfam:zf-C2HC
|
363 |
393 |
2.6e-17 |
PFAM |
|
Pfam:zf-C2HC
|
407 |
437 |
1e-18 |
PFAM |
|
Pfam:MYT1
|
476 |
714 |
1.5e-116 |
PFAM |
|
Pfam:zf-C2HC
|
719 |
749 |
1e-19 |
PFAM |
|
Pfam:zf-C2HC
|
763 |
793 |
1.3e-20 |
PFAM |
|
Pfam:zf-C2HC
|
811 |
841 |
8.9e-19 |
PFAM |
|
Pfam:zf-C2HC
|
864 |
894 |
1.3e-16 |
PFAM |
|
coiled coil region
|
918 |
987 |
N/A |
INTRINSIC |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000132207
AA Change: F78I
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000139838
|
| SMART Domains |
Protein: ENSMUSP00000118129
Gene: ENSMUSG00000033740
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
188 |
198 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000140079
AA Change: F328I
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000118322
Gene: ENSMUSG00000033740
AA Change: F328I
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
188 |
198 |
N/A |
INTRINSIC |
|
Pfam:zf-C2HC
|
363 |
393 |
2.6e-17 |
PFAM |
|
Pfam:zf-C2HC
|
407 |
437 |
1e-18 |
PFAM |
|
Pfam:MYT1
|
476 |
714 |
1.5e-116 |
PFAM |
|
Pfam:zf-C2HC
|
719 |
749 |
1e-19 |
PFAM |
|
Pfam:zf-C2HC
|
763 |
793 |
1.3e-20 |
PFAM |
|
Pfam:zf-C2HC
|
811 |
841 |
8.9e-19 |
PFAM |
|
Pfam:zf-C2HC
|
864 |
894 |
1.3e-16 |
PFAM |
|
coiled coil region
|
918 |
987 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000150761
AA Change: F328I
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000120298
Gene: ENSMUSG00000033740
AA Change: F328I
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
188 |
198 |
N/A |
INTRINSIC |
|
Pfam:zf-C2HC
|
363 |
393 |
2.6e-17 |
PFAM |
|
Pfam:zf-C2HC
|
407 |
437 |
1e-18 |
PFAM |
|
Pfam:MYT1
|
476 |
714 |
1.5e-116 |
PFAM |
|
Pfam:zf-C2HC
|
719 |
749 |
1e-19 |
PFAM |
|
Pfam:zf-C2HC
|
763 |
793 |
1.3e-20 |
PFAM |
|
Pfam:zf-C2HC
|
811 |
841 |
8.9e-19 |
PFAM |
|
Pfam:zf-C2HC
|
864 |
894 |
1.3e-16 |
PFAM |
|
coiled coil region
|
918 |
987 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000151281
AA Change: F328I
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000122055
Gene: ENSMUSG00000033740
AA Change: F328I
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
188 |
198 |
N/A |
INTRINSIC |
|
Pfam:zf-C2HC
|
363 |
393 |
2.6e-17 |
PFAM |
|
Pfam:zf-C2HC
|
407 |
437 |
1e-18 |
PFAM |
|
Pfam:MYT1
|
476 |
714 |
1.5e-116 |
PFAM |
|
Pfam:zf-C2HC
|
719 |
749 |
1e-19 |
PFAM |
|
Pfam:zf-C2HC
|
763 |
793 |
1.3e-20 |
PFAM |
|
Pfam:zf-C2HC
|
811 |
841 |
8.9e-19 |
PFAM |
|
Pfam:zf-C2HC
|
864 |
894 |
1.3e-16 |
PFAM |
|
coiled coil region
|
918 |
987 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000163727
AA Change: F328I
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000131417
Gene: ENSMUSG00000033740
AA Change: F328I
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
188 |
198 |
N/A |
INTRINSIC |
|
Pfam:zf-C2HC
|
365 |
392 |
7.8e-15 |
PFAM |
|
Pfam:zf-C2HC
|
409 |
437 |
4.2e-17 |
PFAM |
|
Pfam:MYT1
|
476 |
713 |
1.3e-75 |
PFAM |
|
Pfam:zf-C2HC
|
721 |
749 |
4e-19 |
PFAM |
|
Pfam:zf-C2HC
|
765 |
793 |
1.7e-19 |
PFAM |
|
Pfam:zf-C2HC
|
813 |
841 |
1.1e-17 |
PFAM |
|
Pfam:zf-C2HC
|
866 |
893 |
9.1e-15 |
PFAM |
|
coiled coil region
|
918 |
987 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 99.0%
- 3x: 97.9%
- 10x: 95.2%
- 20x: 88.6%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 88 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 5730455P16Rik |
G |
T |
11: 80,254,767 (GRCm39) |
Y351* |
probably null |
Het |
| Aadac |
G |
T |
3: 59,943,368 (GRCm39) |
R91L |
possibly damaging |
Het |
| Adgrg1 |
T |
A |
8: 95,738,370 (GRCm39) |
F621Y |
probably damaging |
Het |
| Ankmy1 |
G |
T |
1: 92,812,775 (GRCm39) |
D511E |
probably benign |
Het |
| Anks4b |
A |
T |
7: 119,782,097 (GRCm39) |
D376V |
probably damaging |
Het |
| Aox1 |
G |
T |
1: 58,100,400 (GRCm39) |
C399F |
probably benign |
Het |
| Arfgef1 |
C |
T |
1: 10,269,067 (GRCm39) |
|
probably null |
Het |
| Arhgef4 |
G |
A |
1: 34,849,614 (GRCm39) |
V546M |
probably damaging |
Het |
| Cab39 |
T |
A |
1: 85,765,020 (GRCm39) |
V98E |
probably damaging |
Het |
| Cacna1b |
T |
C |
2: 24,651,856 (GRCm39) |
N108D |
probably damaging |
Het |
| Car15 |
C |
A |
16: 17,654,617 (GRCm39) |
E134* |
probably null |
Het |
| Ccdc80 |
T |
G |
16: 44,915,732 (GRCm39) |
Y163D |
probably damaging |
Het |
| Cdcp3 |
A |
G |
7: 130,841,268 (GRCm39) |
M537V |
probably benign |
Het |
| Col22a1 |
C |
T |
15: 71,740,853 (GRCm39) |
G513D |
unknown |
Het |
| Col8a1 |
T |
C |
16: 57,452,805 (GRCm39) |
D66G |
probably damaging |
Het |
| Crot |
C |
A |
5: 9,018,734 (GRCm39) |
S544I |
probably damaging |
Het |
| Cubn |
G |
T |
2: 13,435,770 (GRCm39) |
P1062Q |
probably damaging |
Het |
| Dcc |
A |
T |
18: 71,553,334 (GRCm39) |
V774E |
probably damaging |
Het |
| Dlgap5 |
T |
A |
14: 47,647,818 (GRCm39) |
M240L |
probably benign |
Het |
| Dlx4 |
A |
G |
11: 95,036,261 (GRCm39) |
V16A |
probably benign |
Het |
| Dnah17 |
G |
T |
11: 117,958,373 (GRCm39) |
H2703Q |
probably benign |
Het |
| Duox2 |
A |
G |
2: 122,122,291 (GRCm39) |
|
probably null |
Het |
| Fn1 |
C |
T |
1: 71,636,844 (GRCm39) |
V168I |
probably damaging |
Het |
| Fpr-rs4 |
A |
T |
17: 18,242,359 (GRCm39) |
D122V |
probably damaging |
Het |
| Gas2l2 |
A |
T |
11: 83,313,923 (GRCm39) |
I463N |
probably benign |
Het |
| Ggta1 |
G |
T |
2: 35,292,416 (GRCm39) |
P297Q |
probably damaging |
Het |
| Gpatch3 |
C |
A |
4: 133,305,457 (GRCm39) |
R231S |
probably damaging |
Het |
| Gpc1 |
T |
C |
1: 92,782,705 (GRCm39) |
Y151H |
probably damaging |
Het |
| Gpr141b |
A |
G |
13: 19,913,317 (GRCm39) |
|
noncoding transcript |
Het |
| Gtf2e2 |
T |
C |
8: 34,245,973 (GRCm39) |
W119R |
probably damaging |
Het |
| H2-M10.2 |
T |
C |
17: 36,595,253 (GRCm39) |
I304V |
probably benign |
Het |
| Helq |
T |
C |
5: 100,927,031 (GRCm39) |
K685R |
probably benign |
Het |
| Hps5 |
C |
T |
7: 46,418,712 (GRCm39) |
|
probably null |
Het |
| Iars1 |
T |
C |
13: 49,885,818 (GRCm39) |
C1186R |
probably damaging |
Het |
| Ift43 |
T |
C |
12: 86,208,795 (GRCm39) |
V158A |
possibly damaging |
Het |
| Ift70b |
A |
G |
2: 75,768,586 (GRCm39) |
Y56H |
probably damaging |
Het |
| Iqca1 |
A |
T |
1: 90,070,429 (GRCm39) |
I141N |
probably damaging |
Het |
| Kat6b |
A |
G |
14: 21,719,149 (GRCm39) |
N1276S |
probably benign |
Het |
| Kif19a |
A |
T |
11: 114,656,340 (GRCm39) |
M1L |
possibly damaging |
Het |
| Kif1b |
T |
G |
4: 149,286,969 (GRCm39) |
H1241P |
probably damaging |
Het |
| Kif26a |
T |
C |
12: 112,144,510 (GRCm39) |
V1588A |
possibly damaging |
Het |
| Klb |
T |
A |
5: 65,529,842 (GRCm39) |
|
probably null |
Het |
| Krtap26-1 |
A |
T |
16: 88,444,131 (GRCm39) |
Y163* |
probably null |
Het |
| Lefty1 |
G |
T |
1: 180,765,199 (GRCm39) |
E256* |
probably null |
Het |
| Lox |
T |
C |
18: 52,662,271 (GRCm39) |
N44S |
possibly damaging |
Het |
| Marf1 |
C |
T |
16: 13,960,398 (GRCm39) |
A549T |
probably damaging |
Het |
| Mctp1 |
A |
G |
13: 76,949,663 (GRCm39) |
Y565C |
probably damaging |
Het |
| Megf6 |
C |
T |
4: 154,349,783 (GRCm39) |
A961V |
probably benign |
Het |
| Mindy4 |
A |
G |
6: 55,253,619 (GRCm39) |
K496R |
probably benign |
Het |
| Nalcn |
A |
T |
14: 123,744,971 (GRCm39) |
H352Q |
probably benign |
Het |
| Ncoa5 |
T |
C |
2: 164,851,310 (GRCm39) |
I188V |
possibly damaging |
Het |
| Notum |
G |
T |
11: 120,545,282 (GRCm39) |
H426N |
probably benign |
Het |
| Or52r1 |
T |
A |
7: 102,536,458 (GRCm39) |
I301F |
possibly damaging |
Het |
| Orm2 |
A |
T |
4: 63,282,233 (GRCm39) |
D137V |
probably damaging |
Het |
| Pabpc2 |
G |
A |
18: 39,908,448 (GRCm39) |
G571D |
probably damaging |
Het |
| Pabpc4 |
A |
G |
4: 123,191,735 (GRCm39) |
N599S |
probably damaging |
Het |
| Pak1ip1 |
T |
C |
13: 41,166,080 (GRCm39) |
V335A |
probably benign |
Het |
| Pcdhb11 |
A |
C |
18: 37,556,446 (GRCm39) |
D592A |
probably damaging |
Het |
| Pmch |
C |
A |
10: 87,927,120 (GRCm39) |
T41K |
possibly damaging |
Het |
| Polb |
G |
T |
8: 23,130,011 (GRCm39) |
S187* |
probably null |
Het |
| Pter |
G |
T |
2: 13,005,753 (GRCm39) |
G309* |
probably null |
Het |
| Ptprg |
T |
C |
14: 12,219,024 (GRCm38) |
V406A |
possibly damaging |
Het |
| Ranbp3l |
A |
T |
15: 9,063,184 (GRCm39) |
E467V |
possibly damaging |
Het |
| Rif1 |
T |
A |
2: 51,975,153 (GRCm39) |
M354K |
probably damaging |
Het |
| Ripk4 |
C |
T |
16: 97,549,312 (GRCm39) |
C248Y |
probably damaging |
Het |
| Slc6a15 |
T |
C |
10: 103,253,914 (GRCm39) |
W617R |
probably damaging |
Het |
| Smyd5 |
C |
T |
6: 85,417,155 (GRCm39) |
Q178* |
probably null |
Het |
| Supt20 |
T |
A |
3: 54,610,570 (GRCm39) |
L124* |
probably null |
Het |
| Tarbp1 |
T |
A |
8: 127,174,223 (GRCm39) |
H861L |
probably benign |
Het |
| Tars1 |
A |
G |
15: 11,390,411 (GRCm39) |
M356T |
probably benign |
Het |
| Tbc1d10a |
A |
G |
11: 4,162,819 (GRCm39) |
T221A |
probably damaging |
Het |
| Tead3 |
A |
G |
17: 28,553,672 (GRCm39) |
|
probably null |
Het |
| Tprg1 |
A |
G |
16: 25,240,985 (GRCm39) |
T254A |
probably damaging |
Het |
| Trank1 |
C |
A |
9: 111,220,545 (GRCm39) |
N2427K |
probably benign |
Het |
| Tufm |
T |
C |
7: 126,089,036 (GRCm39) |
S380P |
probably damaging |
Het |
| Tyrobp |
C |
T |
7: 30,114,042 (GRCm39) |
R68C |
probably damaging |
Het |
| Ubl4b |
T |
C |
3: 107,462,143 (GRCm39) |
E39G |
possibly damaging |
Het |
| Uggt2 |
A |
T |
14: 119,286,863 (GRCm39) |
F661I |
probably damaging |
Het |
| Upf3b |
A |
G |
X: 36,368,120 (GRCm39) |
I144T |
probably benign |
Het |
| Usp54 |
A |
T |
14: 20,611,320 (GRCm39) |
D1165E |
probably benign |
Het |
| Vmn2r81 |
C |
T |
10: 79,129,281 (GRCm39) |
T724I |
possibly damaging |
Het |
| Vsig1 |
A |
G |
X: 139,837,062 (GRCm39) |
I247M |
possibly damaging |
Het |
| Zfp110 |
C |
A |
7: 12,583,187 (GRCm39) |
L612I |
probably benign |
Het |
| Zfp318 |
C |
A |
17: 46,724,222 (GRCm39) |
T2075K |
probably damaging |
Het |
| Zfp37 |
A |
G |
4: 62,110,122 (GRCm39) |
M1T |
probably null |
Het |
| Zfp605 |
T |
A |
5: 110,276,720 (GRCm39) |
C613S |
probably damaging |
Het |
| Zfp729a |
G |
A |
13: 67,769,792 (GRCm39) |
P146S |
possibly damaging |
Het |
| Zfp85 |
T |
C |
13: 67,896,791 (GRCm39) |
N427S |
probably benign |
Het |
|
| Other mutations in St18 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00089:St18
|
APN |
1 |
6,872,796 (GRCm39) |
missense |
probably benign |
0.07 |
|
IGL00840:St18
|
APN |
1 |
6,903,818 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01016:St18
|
APN |
1 |
6,914,547 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01116:St18
|
APN |
1 |
6,872,856 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL01719:St18
|
APN |
1 |
6,916,020 (GRCm39) |
splice site |
probably benign |
|
|
IGL01885:St18
|
APN |
1 |
6,914,596 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02486:St18
|
APN |
1 |
6,890,307 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02611:St18
|
APN |
1 |
6,839,114 (GRCm39) |
splice site |
probably benign |
|
|
IGL02742:St18
|
APN |
1 |
6,872,540 (GRCm39) |
splice site |
probably benign |
|
|
IGL02953:St18
|
APN |
1 |
6,914,337 (GRCm39) |
splice site |
probably benign |
|
|
IGL02999:St18
|
APN |
1 |
6,887,829 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL03092:St18
|
APN |
1 |
6,839,118 (GRCm39) |
splice site |
probably benign |
|
|
Smallish
|
UTSW |
1 |
6,925,697 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL03055:St18
|
UTSW |
1 |
6,872,959 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0089:St18
|
UTSW |
1 |
6,919,172 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0257:St18
|
UTSW |
1 |
6,890,186 (GRCm39) |
missense |
probably benign |
0.04 |
|
R0588:St18
|
UTSW |
1 |
6,887,962 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0989:St18
|
UTSW |
1 |
6,898,105 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1068:St18
|
UTSW |
1 |
6,865,786 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1311:St18
|
UTSW |
1 |
6,915,868 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1530:St18
|
UTSW |
1 |
6,915,793 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R1723:St18
|
UTSW |
1 |
6,880,909 (GRCm39) |
splice site |
probably benign |
|
|
R1926:St18
|
UTSW |
1 |
6,872,913 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1927:St18
|
UTSW |
1 |
6,872,936 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2035:St18
|
UTSW |
1 |
6,872,552 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2091:St18
|
UTSW |
1 |
6,898,195 (GRCm39) |
missense |
probably benign |
0.08 |
|
R2139:St18
|
UTSW |
1 |
6,880,839 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R2261:St18
|
UTSW |
1 |
6,915,796 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R2300:St18
|
UTSW |
1 |
6,925,626 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2322:St18
|
UTSW |
1 |
6,914,348 (GRCm39) |
nonsense |
probably null |
|
|
R2846:St18
|
UTSW |
1 |
6,915,811 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R3738:St18
|
UTSW |
1 |
6,925,697 (GRCm39) |
critical splice donor site |
probably null |
|
|
R3739:St18
|
UTSW |
1 |
6,925,697 (GRCm39) |
critical splice donor site |
probably null |
|
|
R3772:St18
|
UTSW |
1 |
6,914,553 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3805:St18
|
UTSW |
1 |
6,872,577 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3953:St18
|
UTSW |
1 |
6,873,117 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4034:St18
|
UTSW |
1 |
6,925,697 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4036:St18
|
UTSW |
1 |
6,898,010 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4407:St18
|
UTSW |
1 |
6,898,061 (GRCm39) |
missense |
probably benign |
0.29 |
|
R4527:St18
|
UTSW |
1 |
6,925,647 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4740:St18
|
UTSW |
1 |
6,887,828 (GRCm39) |
missense |
probably benign |
|
|
R4838:St18
|
UTSW |
1 |
6,873,129 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5182:St18
|
UTSW |
1 |
6,887,877 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5186:St18
|
UTSW |
1 |
6,872,541 (GRCm39) |
splice site |
probably null |
|
|
R5354:St18
|
UTSW |
1 |
6,914,395 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5423:St18
|
UTSW |
1 |
6,872,840 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R5724:St18
|
UTSW |
1 |
6,841,174 (GRCm39) |
missense |
probably benign |
0.13 |
|
R6182:St18
|
UTSW |
1 |
6,914,342 (GRCm39) |
splice site |
probably null |
|
|
R6491:St18
|
UTSW |
1 |
6,898,209 (GRCm39) |
nonsense |
probably null |
|
|
R6503:St18
|
UTSW |
1 |
6,865,621 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7037:St18
|
UTSW |
1 |
6,873,260 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R7098:St18
|
UTSW |
1 |
6,898,066 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7132:St18
|
UTSW |
1 |
6,929,351 (GRCm39) |
missense |
|
|
|
R7144:St18
|
UTSW |
1 |
6,903,818 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7150:St18
|
UTSW |
1 |
6,873,243 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7334:St18
|
UTSW |
1 |
6,872,783 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7502:St18
|
UTSW |
1 |
6,898,194 (GRCm39) |
missense |
probably benign |
0.09 |
|
R7729:St18
|
UTSW |
1 |
6,872,761 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7848:St18
|
UTSW |
1 |
6,927,669 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8088:St18
|
UTSW |
1 |
6,898,229 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8299:St18
|
UTSW |
1 |
6,873,216 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8338:St18
|
UTSW |
1 |
6,879,516 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8690:St18
|
UTSW |
1 |
6,872,788 (GRCm39) |
missense |
probably benign |
|
|
R8753:St18
|
UTSW |
1 |
6,916,015 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8808:St18
|
UTSW |
1 |
6,880,826 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8880:St18
|
UTSW |
1 |
6,865,619 (GRCm39) |
nonsense |
probably null |
|
|
R9055:St18
|
UTSW |
1 |
6,873,206 (GRCm39) |
nonsense |
probably null |
|
|
R9292:St18
|
UTSW |
1 |
6,898,106 (GRCm39) |
missense |
probably benign |
0.32 |
|
R9322:St18
|
UTSW |
1 |
6,865,747 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9530:St18
|
UTSW |
1 |
6,872,997 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9603:St18
|
UTSW |
1 |
6,915,811 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9611:St18
|
UTSW |
1 |
6,873,147 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9639:St18
|
UTSW |
1 |
6,929,246 (GRCm39) |
missense |
|
|
|
R9644:St18
|
UTSW |
1 |
6,929,276 (GRCm39) |
missense |
|
|
|
R9740:St18
|
UTSW |
1 |
6,873,287 (GRCm39) |
nonsense |
probably null |
|
|
R9750:St18
|
UTSW |
1 |
6,873,216 (GRCm39) |
missense |
probably benign |
0.01 |
|
| Predicted Primers |
PCR Primer
(F):5'- GGCAATGGCTCCAACTCATCAGAAG -3'
(R):5'- TGCAAAGGAAGGAATCGTCTGTCTC -3'
Sequencing Primer
(F):5'- ACCCTTGGTTGTGAAAGCCC -3'
(R):5'- taCATTAAGTTGTCAAAACGCTAATC -3'
|
| Posted On |
2013-04-24 |
Incidental Mutation