Incidental Mutation 'R3970:Zfp219'
| ID |
310939 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Zfp219
|
| Ensembl Gene |
ENSMUSG00000049295 |
| Gene Name |
zinc finger protein 219 |
| Synonyms |
2010302A17Rik |
| MMRRC Submission |
040938-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R3970 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
14 |
| Chromosomal Location |
52243534-52258190 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 52244421 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamine to Leucine
at position 541
(Q541L)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000153966
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000067549]
[ENSMUST00000093813]
[ENSMUST00000100639]
[ENSMUST00000166169]
[ENSMUST00000182061]
[ENSMUST00000226522]
[ENSMUST00000182760]
[ENSMUST00000182909]
[ENSMUST00000183208]
[ENSMUST00000226527]
[ENSMUST00000182905]
[ENSMUST00000228580]
[ENSMUST00000228747]
[ENSMUST00000226964]
[ENSMUST00000228162]
[ENSMUST00000226605]
[ENSMUST00000226554]
[ENSMUST00000228051]
|
| AlphaFold |
Q6IQX8 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000067549
AA Change: Q586L
PolyPhen 2
Score 0.031 (Sensitivity: 0.95; Specificity: 0.82)
|
| SMART Domains |
Protein: ENSMUSP00000068184
Gene: ENSMUSG00000049295
AA Change: Q586L
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
30 |
47 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
61 |
83 |
6.23e-2 |
SMART |
|
ZnF_C2H2
|
89 |
111 |
4.17e-3 |
SMART |
|
low complexity region
|
113 |
146 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
167 |
190 |
3.07e-1 |
SMART |
|
ZnF_C2H2
|
193 |
216 |
1.51e0 |
SMART |
|
low complexity region
|
229 |
276 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
277 |
299 |
8.47e-4 |
SMART |
|
ZnF_C2H2
|
305 |
327 |
1.38e-3 |
SMART |
|
low complexity region
|
331 |
350 |
N/A |
INTRINSIC |
|
low complexity region
|
354 |
379 |
N/A |
INTRINSIC |
|
low complexity region
|
427 |
441 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
501 |
523 |
3.63e-3 |
SMART |
|
ZnF_C2H2
|
529 |
551 |
1.58e-3 |
SMART |
|
low complexity region
|
560 |
570 |
N/A |
INTRINSIC |
|
low complexity region
|
594 |
611 |
N/A |
INTRINSIC |
|
low complexity region
|
637 |
648 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
650 |
672 |
2.82e0 |
SMART |
|
low complexity region
|
675 |
684 |
N/A |
INTRINSIC |
|
low complexity region
|
695 |
714 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000093813
|
| SMART Domains |
Protein: ENSMUSP00000091331
Gene: ENSMUSG00000004562
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
201 |
223 |
N/A |
INTRINSIC |
|
low complexity region
|
306 |
320 |
N/A |
INTRINSIC |
|
low complexity region
|
332 |
345 |
N/A |
INTRINSIC |
|
low complexity region
|
351 |
395 |
N/A |
INTRINSIC |
|
low complexity region
|
451 |
472 |
N/A |
INTRINSIC |
|
low complexity region
|
550 |
564 |
N/A |
INTRINSIC |
|
low complexity region
|
581 |
606 |
N/A |
INTRINSIC |
|
low complexity region
|
773 |
792 |
N/A |
INTRINSIC |
|
low complexity region
|
885 |
914 |
N/A |
INTRINSIC |
|
low complexity region
|
958 |
996 |
N/A |
INTRINSIC |
|
Pfam:RhoGEF
|
1087 |
1246 |
6.1e-9 |
PFAM |
|
PH
|
1264 |
1372 |
3.97e-8 |
SMART |
|
low complexity region
|
1403 |
1424 |
N/A |
INTRINSIC |
|
low complexity region
|
1478 |
1491 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000100639
|
| SMART Domains |
Protein: ENSMUSP00000098204
Gene: ENSMUSG00000004562
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
201 |
223 |
N/A |
INTRINSIC |
|
low complexity region
|
306 |
320 |
N/A |
INTRINSIC |
|
low complexity region
|
332 |
345 |
N/A |
INTRINSIC |
|
low complexity region
|
351 |
395 |
N/A |
INTRINSIC |
|
low complexity region
|
451 |
472 |
N/A |
INTRINSIC |
|
low complexity region
|
550 |
564 |
N/A |
INTRINSIC |
|
low complexity region
|
581 |
606 |
N/A |
INTRINSIC |
|
low complexity region
|
773 |
792 |
N/A |
INTRINSIC |
|
low complexity region
|
885 |
914 |
N/A |
INTRINSIC |
|
low complexity region
|
958 |
996 |
N/A |
INTRINSIC |
|
Pfam:RhoGEF
|
1087 |
1246 |
5.9e-9 |
PFAM |
|
PH
|
1264 |
1372 |
3.97e-8 |
SMART |
|
low complexity region
|
1430 |
1443 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000166169
AA Change: Q586L
PolyPhen 2
Score 0.031 (Sensitivity: 0.95; Specificity: 0.82)
|
| SMART Domains |
Protein: ENSMUSP00000126854
Gene: ENSMUSG00000049295
AA Change: Q586L
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
30 |
47 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
61 |
83 |
6.23e-2 |
SMART |
|
ZnF_C2H2
|
89 |
111 |
4.17e-3 |
SMART |
|
low complexity region
|
113 |
146 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
167 |
190 |
3.07e-1 |
SMART |
|
ZnF_C2H2
|
193 |
216 |
1.51e0 |
SMART |
|
low complexity region
|
229 |
276 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
277 |
299 |
8.47e-4 |
SMART |
|
ZnF_C2H2
|
305 |
327 |
1.38e-3 |
SMART |
|
low complexity region
|
331 |
350 |
N/A |
INTRINSIC |
|
low complexity region
|
354 |
379 |
N/A |
INTRINSIC |
|
low complexity region
|
427 |
441 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
501 |
523 |
3.63e-3 |
SMART |
|
ZnF_C2H2
|
529 |
551 |
1.58e-3 |
SMART |
|
low complexity region
|
560 |
570 |
N/A |
INTRINSIC |
|
low complexity region
|
594 |
611 |
N/A |
INTRINSIC |
|
low complexity region
|
637 |
648 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
650 |
672 |
2.82e0 |
SMART |
|
low complexity region
|
675 |
684 |
N/A |
INTRINSIC |
|
low complexity region
|
695 |
714 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000182061
|
| SMART Domains |
Protein: ENSMUSP00000138128
Gene: ENSMUSG00000004562
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
201 |
223 |
N/A |
INTRINSIC |
|
low complexity region
|
306 |
320 |
N/A |
INTRINSIC |
|
low complexity region
|
332 |
345 |
N/A |
INTRINSIC |
|
low complexity region
|
351 |
395 |
N/A |
INTRINSIC |
|
low complexity region
|
451 |
472 |
N/A |
INTRINSIC |
|
low complexity region
|
550 |
564 |
N/A |
INTRINSIC |
|
low complexity region
|
581 |
606 |
N/A |
INTRINSIC |
|
low complexity region
|
773 |
792 |
N/A |
INTRINSIC |
|
low complexity region
|
885 |
914 |
N/A |
INTRINSIC |
|
low complexity region
|
958 |
996 |
N/A |
INTRINSIC |
|
Pfam:RhoGEF
|
1087 |
1247 |
3.7e-9 |
PFAM |
|
PH
|
1264 |
1372 |
3.97e-8 |
SMART |
|
low complexity region
|
1430 |
1443 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000182217
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000182504
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000182931
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000182777
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000183213
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000182644
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000183022
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000226522
AA Change: Q586L
PolyPhen 2
Score 0.031 (Sensitivity: 0.95; Specificity: 0.82)
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000226474
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000182760
|
| SMART Domains |
Protein: ENSMUSP00000138125
Gene: ENSMUSG00000004562
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
201 |
223 |
N/A |
INTRINSIC |
|
low complexity region
|
306 |
320 |
N/A |
INTRINSIC |
|
low complexity region
|
332 |
345 |
N/A |
INTRINSIC |
|
low complexity region
|
351 |
395 |
N/A |
INTRINSIC |
|
low complexity region
|
451 |
472 |
N/A |
INTRINSIC |
|
low complexity region
|
550 |
564 |
N/A |
INTRINSIC |
|
low complexity region
|
581 |
606 |
N/A |
INTRINSIC |
|
low complexity region
|
782 |
801 |
N/A |
INTRINSIC |
|
low complexity region
|
894 |
923 |
N/A |
INTRINSIC |
|
low complexity region
|
967 |
1005 |
N/A |
INTRINSIC |
|
Pfam:RhoGEF
|
1096 |
1256 |
5.9e-9 |
PFAM |
|
PH
|
1273 |
1381 |
3.97e-8 |
SMART |
|
low complexity region
|
1412 |
1433 |
N/A |
INTRINSIC |
|
low complexity region
|
1487 |
1500 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000182828
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000182909
|
| SMART Domains |
Protein: ENSMUSP00000138635
Gene: ENSMUSG00000004562
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
201 |
223 |
N/A |
INTRINSIC |
|
low complexity region
|
306 |
320 |
N/A |
INTRINSIC |
|
low complexity region
|
332 |
345 |
N/A |
INTRINSIC |
|
low complexity region
|
351 |
395 |
N/A |
INTRINSIC |
|
low complexity region
|
451 |
472 |
N/A |
INTRINSIC |
|
low complexity region
|
550 |
564 |
N/A |
INTRINSIC |
|
low complexity region
|
581 |
606 |
N/A |
INTRINSIC |
|
low complexity region
|
773 |
792 |
N/A |
INTRINSIC |
|
low complexity region
|
885 |
914 |
N/A |
INTRINSIC |
|
low complexity region
|
958 |
996 |
N/A |
INTRINSIC |
|
Pfam:RhoGEF
|
1087 |
1247 |
3.9e-9 |
PFAM |
|
PH
|
1264 |
1372 |
3.97e-8 |
SMART |
|
low complexity region
|
1403 |
1424 |
N/A |
INTRINSIC |
|
low complexity region
|
1478 |
1491 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000183208
|
| SMART Domains |
Protein: ENSMUSP00000138354
Gene: ENSMUSG00000004562
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
201 |
223 |
N/A |
INTRINSIC |
|
low complexity region
|
306 |
320 |
N/A |
INTRINSIC |
|
low complexity region
|
332 |
345 |
N/A |
INTRINSIC |
|
low complexity region
|
351 |
395 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000182667
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000226527
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000182905
|
| SMART Domains |
Protein: ENSMUSP00000138797
Gene: ENSMUSG00000004562
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
201 |
223 |
N/A |
INTRINSIC |
|
low complexity region
|
306 |
320 |
N/A |
INTRINSIC |
|
low complexity region
|
332 |
345 |
N/A |
INTRINSIC |
|
low complexity region
|
351 |
395 |
N/A |
INTRINSIC |
|
low complexity region
|
451 |
472 |
N/A |
INTRINSIC |
|
low complexity region
|
550 |
564 |
N/A |
INTRINSIC |
|
low complexity region
|
581 |
606 |
N/A |
INTRINSIC |
|
low complexity region
|
773 |
792 |
N/A |
INTRINSIC |
|
low complexity region
|
885 |
914 |
N/A |
INTRINSIC |
|
low complexity region
|
958 |
996 |
N/A |
INTRINSIC |
|
SCOP:d1kz7a1
|
1073 |
1162 |
4e-7 |
SMART |
|
Blast:RhoGEF
|
1087 |
1157 |
1e-8 |
BLAST |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000228580
AA Change: Q541L
PolyPhen 2
Score 0.052 (Sensitivity: 0.94; Specificity: 0.83)
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000228747
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000226964
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000228162
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000226605
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000226554
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000228051
|
| Meta Mutation Damage Score |
0.0898 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.1%
- 20x: 94.4%
|
| Validation Efficiency |
96% (53/55) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 54 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2510039O18Rik |
T |
C |
4: 148,029,779 (GRCm39) |
M583T |
probably damaging |
Het |
| Actn4 |
T |
C |
7: 28,661,457 (GRCm39) |
K51R |
probably benign |
Het |
| Adamts15 |
T |
C |
9: 30,821,898 (GRCm39) |
Y513C |
probably benign |
Het |
| Akap13 |
T |
A |
7: 75,219,699 (GRCm39) |
L34* |
probably null |
Het |
| Akap6 |
A |
T |
12: 53,188,236 (GRCm39) |
K1883N |
probably damaging |
Het |
| Ano1 |
T |
C |
7: 144,161,700 (GRCm39) |
N749D |
probably benign |
Het |
| Armcx6 |
G |
T |
X: 133,650,505 (GRCm39) |
H109N |
possibly damaging |
Het |
| Camk4 |
T |
A |
18: 33,312,634 (GRCm39) |
I258N |
possibly damaging |
Het |
| Cdhr2 |
A |
T |
13: 54,874,271 (GRCm39) |
N781I |
probably damaging |
Het |
| Cherp |
T |
C |
8: 73,223,795 (GRCm39) |
H196R |
possibly damaging |
Het |
| Chia1 |
T |
G |
3: 106,028,951 (GRCm39) |
|
probably null |
Het |
| Col11a1 |
A |
T |
3: 113,890,838 (GRCm39) |
T392S |
unknown |
Het |
| Commd9 |
C |
A |
2: 101,727,486 (GRCm39) |
N93K |
probably benign |
Het |
| Csf2rb |
T |
C |
15: 78,225,667 (GRCm39) |
V286A |
probably benign |
Het |
| Dnah17 |
G |
A |
11: 117,931,984 (GRCm39) |
|
probably benign |
Het |
| E2f1 |
C |
G |
2: 154,405,942 (GRCm39) |
G144R |
probably damaging |
Het |
| Fcho2 |
A |
T |
13: 98,871,564 (GRCm39) |
S551T |
probably benign |
Het |
| Flna |
A |
T |
X: 73,279,273 (GRCm39) |
V1253E |
probably damaging |
Het |
| Gm12185 |
A |
T |
11: 48,798,172 (GRCm39) |
C774S |
probably benign |
Het |
| Gm14401 |
T |
C |
2: 176,778,789 (GRCm39) |
Y292H |
possibly damaging |
Het |
| Insyn2b |
A |
T |
11: 34,369,739 (GRCm39) |
Q481L |
probably damaging |
Het |
| Kif5c |
A |
G |
2: 49,578,756 (GRCm39) |
E128G |
probably damaging |
Het |
| Lama3 |
A |
T |
18: 12,713,398 (GRCm39) |
K3230M |
probably damaging |
Het |
| Myof |
C |
T |
19: 37,889,711 (GRCm39) |
V1287M |
probably damaging |
Het |
| Myof |
T |
G |
19: 38,011,058 (GRCm39) |
D60A |
possibly damaging |
Het |
| Myrf |
A |
G |
19: 10,200,601 (GRCm39) |
L332P |
probably damaging |
Het |
| Nampt |
T |
A |
12: 32,883,095 (GRCm39) |
D93E |
probably benign |
Het |
| Narf |
A |
T |
11: 121,129,247 (GRCm39) |
E10D |
possibly damaging |
Het |
| Nlrp6 |
C |
A |
7: 140,501,568 (GRCm39) |
A45E |
probably damaging |
Het |
| Obscn |
G |
A |
11: 58,942,488 (GRCm39) |
P4898L |
probably damaging |
Het |
| Or8c11 |
T |
C |
9: 38,289,222 (GRCm39) |
V15A |
probably damaging |
Het |
| Pabpc5 |
A |
G |
X: 118,838,321 (GRCm39) |
E212G |
probably benign |
Het |
| Pcdh8 |
C |
T |
14: 80,007,706 (GRCm39) |
G286S |
possibly damaging |
Het |
| Pcdha2 |
C |
A |
18: 37,073,750 (GRCm39) |
Y460* |
probably null |
Het |
| Pcdhga4 |
G |
T |
18: 37,820,654 (GRCm39) |
L734F |
possibly damaging |
Het |
| Pecr |
G |
A |
1: 72,315,468 (GRCm39) |
T94I |
probably damaging |
Het |
| Piezo2 |
A |
T |
18: 63,144,767 (GRCm39) |
V2776E |
probably damaging |
Het |
| Pign |
A |
C |
1: 105,583,728 (GRCm39) |
S125A |
probably damaging |
Het |
| Pik3r2 |
G |
A |
8: 71,223,065 (GRCm39) |
R452C |
probably benign |
Het |
| Pkd1l1 |
C |
T |
11: 8,824,218 (GRCm39) |
E1566K |
probably damaging |
Het |
| Plcb2 |
A |
G |
2: 118,546,171 (GRCm39) |
|
probably benign |
Het |
| Ppl |
T |
C |
16: 4,918,196 (GRCm39) |
|
probably null |
Het |
| Pramel4 |
A |
T |
4: 143,795,044 (GRCm39) |
N477I |
possibly damaging |
Het |
| Psd |
C |
T |
19: 46,312,845 (GRCm39) |
R175H |
probably benign |
Het |
| Sema3g |
T |
C |
14: 30,948,478 (GRCm39) |
|
probably null |
Het |
| Sf3b1 |
G |
A |
1: 55,051,341 (GRCm39) |
R196* |
probably null |
Het |
| Slc26a4 |
G |
T |
12: 31,578,686 (GRCm39) |
H656N |
probably damaging |
Het |
| Slc6a7 |
A |
C |
18: 61,136,417 (GRCm39) |
L328R |
possibly damaging |
Het |
| Stab2 |
T |
C |
10: 86,714,750 (GRCm39) |
T139A |
probably damaging |
Het |
| Tiam2 |
T |
A |
17: 3,479,106 (GRCm39) |
I613N |
probably damaging |
Het |
| Tlk1 |
A |
G |
2: 70,546,996 (GRCm39) |
V695A |
probably damaging |
Het |
| Trpc2 |
A |
G |
7: 101,733,531 (GRCm39) |
D160G |
probably damaging |
Het |
| Uhrf2 |
T |
C |
19: 30,057,315 (GRCm39) |
V491A |
probably damaging |
Het |
| Vwa7 |
G |
A |
17: 35,236,684 (GRCm39) |
A84T |
probably damaging |
Het |
|
| Other mutations in Zfp219 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL02134:Zfp219
|
APN |
14 |
52,246,758 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Bart
|
UTSW |
14 |
52,244,163 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Bert
|
UTSW |
14 |
52,244,395 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0019:Zfp219
|
UTSW |
14 |
52,246,485 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0103:Zfp219
|
UTSW |
14 |
52,244,163 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0811:Zfp219
|
UTSW |
14 |
52,244,395 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0812:Zfp219
|
UTSW |
14 |
52,244,395 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1677:Zfp219
|
UTSW |
14 |
52,246,512 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1773:Zfp219
|
UTSW |
14 |
52,244,563 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1921:Zfp219
|
UTSW |
14 |
52,245,691 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2929:Zfp219
|
UTSW |
14 |
52,246,436 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4485:Zfp219
|
UTSW |
14 |
52,244,841 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5020:Zfp219
|
UTSW |
14 |
52,247,112 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5206:Zfp219
|
UTSW |
14 |
52,247,022 (GRCm39) |
missense |
probably benign |
0.40 |
|
R5244:Zfp219
|
UTSW |
14 |
52,245,999 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R5907:Zfp219
|
UTSW |
14 |
52,244,606 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R6903:Zfp219
|
UTSW |
14 |
52,244,118 (GRCm39) |
missense |
probably benign |
0.31 |
|
R7409:Zfp219
|
UTSW |
14 |
52,244,570 (GRCm39) |
nonsense |
probably null |
|
|
R8725:Zfp219
|
UTSW |
14 |
52,244,899 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R8937:Zfp219
|
UTSW |
14 |
52,244,224 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9135:Zfp219
|
UTSW |
14 |
52,244,598 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9157:Zfp219
|
UTSW |
14 |
52,246,200 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9203:Zfp219
|
UTSW |
14 |
52,246,405 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9297:Zfp219
|
UTSW |
14 |
52,246,494 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9313:Zfp219
|
UTSW |
14 |
52,246,200 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9717:Zfp219
|
UTSW |
14 |
52,247,049 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- ATGCAAGGCCATGAGCTCAG -3'
(R):5'- TGTCCACACTGCGACTATGC -3'
Sequencing Primer
(F):5'- TCAGGAGCTCCAGTGGCAAAG -3'
(R):5'- ACTATGCAGGTACCCAGTCG -3'
|
| Posted On |
2015-04-29 |
Incidental Mutation