Incidental Mutation 'R0387:Ly75'
| ID |
31322 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ly75
|
| Ensembl Gene |
ENSMUSG00000026980 |
| Gene Name |
lymphocyte antigen 75 |
| Synonyms |
DEC-205, CD205 |
| MMRRC Submission |
038593-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R0387 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
2 |
| Chromosomal Location |
60292103-60383303 bp(-) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 60306404 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Tyrosine to Phenylalanine
at position 1493
(Y1493F)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000028362
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000028362]
[ENSMUST00000112533]
|
| AlphaFold |
Q60767 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000028362
AA Change: Y1493F
PolyPhen 2
Score 0.204 (Sensitivity: 0.92; Specificity: 0.88)
|
| SMART Domains |
Protein: ENSMUSP00000028362
Gene: ENSMUSG00000026980
AA Change: Y1493F
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
27 |
N/A |
INTRINSIC |
|
RICIN
|
33 |
146 |
2.63e-17 |
SMART |
|
FN2
|
162 |
209 |
1.22e-23 |
SMART |
|
CLECT
|
216 |
341 |
7.36e-32 |
SMART |
|
CLECT
|
361 |
486 |
9.28e-29 |
SMART |
|
CLECT
|
501 |
624 |
1.11e-17 |
SMART |
|
CLECT
|
643 |
791 |
1.93e-26 |
SMART |
|
CLECT
|
811 |
932 |
7.94e-2 |
SMART |
|
CLECT
|
952 |
1091 |
5.81e-21 |
SMART |
|
CLECT
|
1104 |
1222 |
1.04e-22 |
SMART |
|
CLECT
|
1240 |
1382 |
3.48e-10 |
SMART |
|
CLECT
|
1395 |
1513 |
9.59e-22 |
SMART |
|
CLECT
|
1530 |
1661 |
7.79e-22 |
SMART |
|
transmembrane domain
|
1670 |
1692 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000112533
AA Change: Y1493F
PolyPhen 2
Score 0.123 (Sensitivity: 0.93; Specificity: 0.86)
|
| SMART Domains |
Protein: ENSMUSP00000108152
Gene: ENSMUSG00000026980
AA Change: Y1493F
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
27 |
N/A |
INTRINSIC |
|
RICIN
|
33 |
146 |
2.63e-17 |
SMART |
|
FN2
|
162 |
209 |
1.22e-23 |
SMART |
|
CLECT
|
216 |
341 |
7.36e-32 |
SMART |
|
CLECT
|
361 |
486 |
9.28e-29 |
SMART |
|
CLECT
|
501 |
624 |
1.11e-17 |
SMART |
|
CLECT
|
643 |
791 |
1.93e-26 |
SMART |
|
CLECT
|
811 |
932 |
7.94e-2 |
SMART |
|
CLECT
|
952 |
1091 |
5.81e-21 |
SMART |
|
CLECT
|
1104 |
1222 |
1.04e-22 |
SMART |
|
CLECT
|
1240 |
1382 |
3.48e-10 |
SMART |
|
CLECT
|
1395 |
1513 |
9.59e-22 |
SMART |
|
CLECT
|
1530 |
1661 |
7.79e-22 |
SMART |
|
transmembrane domain
|
1670 |
1692 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.0898 |
| Coding Region Coverage |
- 1x: 98.9%
- 3x: 97.7%
- 10x: 94.2%
- 20x: 85.0%
|
| Validation Efficiency |
99% (77/78) |
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a knock-out allele display abnormalities in CD8-positive T cell morphology and cytotoxic T cell physiology. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(7) : Targeted, knock-out(1) Targeted, other(1) Gene trapped(5)
|
| Other mutations in this stock |
Total: 79 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca15 |
T |
G |
7: 120,332,852 (GRCm38) |
|
probably null |
Het |
| Abcc9 |
T |
A |
6: 142,639,504 (GRCm38) |
K825* |
probably null |
Het |
| Afp |
T |
C |
5: 90,497,291 (GRCm38) |
C189R |
probably damaging |
Het |
| Akap9 |
T |
C |
5: 3,951,678 (GRCm38) |
|
probably benign |
Het |
| Alpk3 |
A |
T |
7: 81,104,227 (GRCm38) |
T1652S |
possibly damaging |
Het |
| Atg4b |
C |
A |
1: 93,786,556 (GRCm38) |
Q354K |
probably benign |
Het |
| Atxn2 |
T |
C |
5: 121,802,143 (GRCm38) |
S388P |
possibly damaging |
Het |
| C2cd3 |
T |
A |
7: 100,422,507 (GRCm38) |
|
probably benign |
Het |
| Cacna2d2 |
C |
A |
9: 107,513,881 (GRCm38) |
T403K |
probably damaging |
Het |
| Cap2 |
C |
T |
13: 46,560,516 (GRCm38) |
H79Y |
probably damaging |
Het |
| Car10 |
G |
T |
11: 93,583,021 (GRCm38) |
|
probably null |
Het |
| Ccno |
T |
C |
13: 112,989,867 (GRCm38) |
L290P |
probably damaging |
Het |
| Cfap69 |
T |
C |
5: 5,589,303 (GRCm38) |
K624E |
probably damaging |
Het |
| Ctnna3 |
A |
G |
10: 64,586,130 (GRCm38) |
M568V |
probably benign |
Het |
| Cyp1b1 |
C |
A |
17: 79,713,774 (GRCm38) |
V180L |
probably benign |
Het |
| Cyp2u1 |
G |
T |
3: 131,295,552 (GRCm38) |
|
probably null |
Het |
| Dcp1a |
T |
C |
14: 30,519,679 (GRCm38) |
|
probably null |
Het |
| Dnm1 |
C |
T |
2: 32,320,581 (GRCm38) |
G1S |
possibly damaging |
Het |
| Dnmt1 |
A |
G |
9: 20,918,213 (GRCm38) |
L698P |
probably damaging |
Het |
| Dock10 |
C |
A |
1: 80,540,276 (GRCm38) |
C1327F |
probably damaging |
Het |
| Dph3b-ps |
A |
G |
13: 106,546,855 (GRCm38) |
|
noncoding transcript |
Het |
| Dpyd |
G |
A |
3: 119,427,226 (GRCm38) |
D949N |
probably benign |
Het |
| Dync2li1 |
A |
G |
17: 84,655,340 (GRCm38) |
K345E |
possibly damaging |
Het |
| Eml2 |
T |
A |
7: 19,182,259 (GRCm38) |
|
probably null |
Het |
| Exoc7 |
A |
G |
11: 116,294,401 (GRCm38) |
|
probably benign |
Het |
| Faah |
A |
T |
4: 116,005,692 (GRCm38) |
C113* |
probably null |
Het |
| Fcf1 |
T |
A |
12: 84,973,002 (GRCm38) |
D16E |
probably benign |
Het |
| Fcgbp |
T |
C |
7: 28,091,454 (GRCm38) |
|
probably benign |
Het |
| Ghr |
A |
G |
15: 3,319,891 (GRCm38) |
S602P |
probably benign |
Het |
| Gm10334 |
A |
G |
6: 41,443,369 (GRCm38) |
I141T |
possibly damaging |
Het |
| Gm5114 |
T |
C |
7: 39,408,809 (GRCm38) |
D462G |
probably benign |
Het |
| Gm8186 |
T |
A |
17: 26,099,026 (GRCm38) |
S66C |
probably damaging |
Het |
| Gorab |
C |
T |
1: 163,396,834 (GRCm38) |
V133M |
probably benign |
Het |
| Gria1 |
G |
A |
11: 57,309,884 (GRCm38) |
|
probably null |
Het |
| Grik1 |
T |
A |
16: 88,034,350 (GRCm38) |
|
probably benign |
Het |
| Gtf3c1 |
A |
G |
7: 125,681,104 (GRCm38) |
L378P |
probably damaging |
Het |
| Htr5b |
A |
T |
1: 121,527,546 (GRCm38) |
V215D |
probably damaging |
Het |
| Htra1 |
A |
G |
7: 130,979,478 (GRCm38) |
T319A |
probably damaging |
Het |
| Idh2 |
C |
T |
7: 80,098,257 (GRCm38) |
A232T |
probably damaging |
Het |
| Klrb1a |
A |
C |
6: 128,609,734 (GRCm38) |
H189Q |
possibly damaging |
Het |
| Lhfp |
A |
G |
3: 53,043,328 (GRCm38) |
T8A |
probably benign |
Het |
| Mfsd5 |
T |
C |
15: 102,281,096 (GRCm38) |
I301T |
possibly damaging |
Het |
| Mlkl |
C |
T |
8: 111,333,350 (GRCm38) |
E135K |
probably damaging |
Het |
| Mrgprx2 |
A |
C |
7: 48,499,160 (GRCm38) |
M1R |
probably null |
Het |
| Mroh2a |
G |
C |
1: 88,246,042 (GRCm38) |
A871P |
probably damaging |
Het |
| Mtbp |
A |
G |
15: 55,611,029 (GRCm38) |
I280V |
possibly damaging |
Het |
| Myo5c |
A |
T |
9: 75,285,021 (GRCm38) |
|
probably benign |
Het |
| Nos3 |
A |
G |
5: 24,367,585 (GRCm38) |
K174R |
probably damaging |
Het |
| Oas2 |
A |
T |
5: 120,745,672 (GRCm38) |
|
probably benign |
Het |
| Olfr889 |
T |
A |
9: 38,115,770 (GRCm38) |
|
probably null |
Het |
| Pi4kb |
G |
C |
3: 94,984,740 (GRCm38) |
E256Q |
probably benign |
Het |
| Pik3c2a |
T |
A |
7: 116,373,744 (GRCm38) |
I739F |
probably damaging |
Het |
| Pla2r1 |
T |
A |
2: 60,432,601 (GRCm38) |
K1031N |
probably benign |
Het |
| Plk4 |
A |
T |
3: 40,812,884 (GRCm38) |
|
probably benign |
Het |
| Polq |
G |
T |
16: 37,089,317 (GRCm38) |
E2354D |
probably damaging |
Het |
| Polq |
T |
C |
16: 37,029,430 (GRCm38) |
C349R |
probably damaging |
Het |
| Prss22 |
A |
G |
17: 23,993,929 (GRCm38) |
L278P |
probably damaging |
Het |
| Ptprk |
G |
A |
10: 28,354,629 (GRCm38) |
V239I |
possibly damaging |
Het |
| Raph1 |
T |
G |
1: 60,510,496 (GRCm38) |
|
probably benign |
Het |
| Rif1 |
GCCACCA |
GCCA |
2: 52,110,324 (GRCm38) |
|
probably benign |
Het |
| Ripor3 |
C |
T |
2: 167,983,772 (GRCm38) |
W755* |
probably null |
Het |
| Rnd3 |
G |
T |
2: 51,148,231 (GRCm38) |
D77E |
probably damaging |
Het |
| Ryr1 |
T |
C |
7: 29,083,367 (GRCm38) |
|
probably benign |
Het |
| Serpinb1a |
C |
T |
13: 32,848,738 (GRCm38) |
V63I |
probably benign |
Het |
| Six1 |
T |
G |
12: 73,046,041 (GRCm38) |
Y129S |
probably damaging |
Het |
| Spata31d1a |
G |
A |
13: 59,703,501 (GRCm38) |
T271I |
probably damaging |
Het |
| Stab1 |
T |
C |
14: 31,148,101 (GRCm38) |
D1387G |
probably benign |
Het |
| Stra6 |
T |
A |
9: 58,153,183 (GRCm38) |
M625K |
probably benign |
Het |
| Syne1 |
T |
C |
10: 5,351,029 (GRCm38) |
S900G |
probably benign |
Het |
| Tdpoz4 |
A |
C |
3: 93,796,700 (GRCm38) |
K101N |
probably benign |
Het |
| Tigd2 |
T |
C |
6: 59,211,158 (GRCm38) |
Y337H |
probably benign |
Het |
| Tnxb |
A |
G |
17: 34,683,574 (GRCm38) |
I1134V |
probably benign |
Het |
| Tspyl5 |
A |
G |
15: 33,686,935 (GRCm38) |
I288T |
probably damaging |
Het |
| Ulk1 |
A |
G |
5: 110,788,797 (GRCm38) |
V61A |
possibly damaging |
Het |
| Xxylt1 |
A |
G |
16: 30,957,376 (GRCm38) |
Y381H |
probably benign |
Het |
| Zcchc9 |
T |
A |
13: 91,800,947 (GRCm38) |
M12L |
probably benign |
Het |
| Zfp106 |
T |
C |
2: 120,528,472 (GRCm38) |
|
probably null |
Het |
| Zfp74 |
T |
A |
7: 29,934,754 (GRCm38) |
T510S |
probably benign |
Het |
| Zfp808 |
A |
G |
13: 62,169,478 (GRCm38) |
T14A |
probably damaging |
Het |
|
| Other mutations in Ly75 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00561:Ly75
|
APN |
2 |
60,376,077 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01072:Ly75
|
APN |
2 |
60,354,496 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01409:Ly75
|
APN |
2 |
60,321,692 (GRCm38) |
splice site |
probably null |
|
|
IGL01432:Ly75
|
APN |
2 |
60,376,007 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01626:Ly75
|
APN |
2 |
60,301,015 (GRCm38) |
missense |
probably benign |
0.13 |
|
IGL01690:Ly75
|
APN |
2 |
60,338,311 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01862:Ly75
|
APN |
2 |
60,299,172 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01982:Ly75
|
APN |
2 |
60,311,764 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02075:Ly75
|
APN |
2 |
60,352,356 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL02338:Ly75
|
APN |
2 |
60,354,452 (GRCm38) |
missense |
probably benign |
0.04 |
|
IGL02364:Ly75
|
APN |
2 |
60,358,507 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02456:Ly75
|
APN |
2 |
60,293,781 (GRCm38) |
missense |
probably benign |
0.09 |
|
IGL02474:Ly75
|
APN |
2 |
60,383,182 (GRCm38) |
missense |
probably null |
1.00 |
|
IGL02608:Ly75
|
APN |
2 |
60,321,900 (GRCm38) |
missense |
probably benign |
0.41 |
|
IGL02986:Ly75
|
APN |
2 |
60,308,191 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03015:Ly75
|
APN |
2 |
60,376,160 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03049:Ly75
|
APN |
2 |
60,352,070 (GRCm38) |
missense |
probably damaging |
0.99 |
|
euphues
|
UTSW |
2 |
60,299,045 (GRCm38) |
critical splice donor site |
probably null |
|
|
four_score
|
UTSW |
2 |
60,311,771 (GRCm38) |
missense |
possibly damaging |
0.75 |
|
lyly
|
UTSW |
2 |
60,327,873 (GRCm38) |
missense |
possibly damaging |
0.49 |
|
Witty
|
UTSW |
2 |
60,354,500 (GRCm38) |
missense |
probably damaging |
1.00 |
|
D605:Ly75
|
UTSW |
2 |
60,352,352 (GRCm38) |
critical splice donor site |
probably null |
|
|
R0046:Ly75
|
UTSW |
2 |
60,339,457 (GRCm38) |
intron |
probably benign |
|
|
R0055:Ly75
|
UTSW |
2 |
60,321,918 (GRCm38) |
missense |
probably benign |
0.01 |
|
R0055:Ly75
|
UTSW |
2 |
60,321,918 (GRCm38) |
missense |
probably benign |
0.01 |
|
R0071:Ly75
|
UTSW |
2 |
60,321,819 (GRCm38) |
missense |
probably benign |
0.01 |
|
R0071:Ly75
|
UTSW |
2 |
60,321,819 (GRCm38) |
missense |
probably benign |
0.01 |
|
R0285:Ly75
|
UTSW |
2 |
60,318,319 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0492:Ly75
|
UTSW |
2 |
60,308,276 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0688:Ly75
|
UTSW |
2 |
60,316,221 (GRCm38) |
missense |
probably benign |
0.41 |
|
R1367:Ly75
|
UTSW |
2 |
60,293,758 (GRCm38) |
splice site |
probably null |
|
|
R1463:Ly75
|
UTSW |
2 |
60,368,757 (GRCm38) |
critical splice donor site |
probably null |
|
|
R1581:Ly75
|
UTSW |
2 |
60,327,893 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1663:Ly75
|
UTSW |
2 |
60,314,234 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1818:Ly75
|
UTSW |
2 |
60,311,777 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1881:Ly75
|
UTSW |
2 |
60,349,940 (GRCm38) |
missense |
probably benign |
0.00 |
|
R2244:Ly75
|
UTSW |
2 |
60,349,913 (GRCm38) |
missense |
probably benign |
0.01 |
|
R2905:Ly75
|
UTSW |
2 |
60,334,554 (GRCm38) |
missense |
probably benign |
0.00 |
|
R3967:Ly75
|
UTSW |
2 |
60,327,873 (GRCm38) |
missense |
possibly damaging |
0.49 |
|
R3968:Ly75
|
UTSW |
2 |
60,327,873 (GRCm38) |
missense |
possibly damaging |
0.49 |
|
R4039:Ly75
|
UTSW |
2 |
60,352,995 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4406:Ly75
|
UTSW |
2 |
60,354,550 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4526:Ly75
|
UTSW |
2 |
60,330,773 (GRCm38) |
missense |
probably benign |
0.09 |
|
R4647:Ly75
|
UTSW |
2 |
60,308,278 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4795:Ly75
|
UTSW |
2 |
60,349,940 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4796:Ly75
|
UTSW |
2 |
60,349,940 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4962:Ly75
|
UTSW |
2 |
60,352,125 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4979:Ly75
|
UTSW |
2 |
60,375,894 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5072:Ly75
|
UTSW |
2 |
60,375,963 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5288:Ly75
|
UTSW |
2 |
60,303,641 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5373:Ly75
|
UTSW |
2 |
60,311,771 (GRCm38) |
missense |
possibly damaging |
0.75 |
|
R5374:Ly75
|
UTSW |
2 |
60,311,771 (GRCm38) |
missense |
possibly damaging |
0.75 |
|
R5384:Ly75
|
UTSW |
2 |
60,334,487 (GRCm38) |
nonsense |
probably null |
|
|
R5385:Ly75
|
UTSW |
2 |
60,303,641 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5395:Ly75
|
UTSW |
2 |
60,365,111 (GRCm38) |
missense |
probably benign |
0.41 |
|
R5531:Ly75
|
UTSW |
2 |
60,365,145 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R5662:Ly75
|
UTSW |
2 |
60,352,381 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5667:Ly75
|
UTSW |
2 |
60,308,311 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5668:Ly75
|
UTSW |
2 |
60,354,500 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5671:Ly75
|
UTSW |
2 |
60,308,311 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5677:Ly75
|
UTSW |
2 |
60,299,082 (GRCm38) |
missense |
probably benign |
0.00 |
|
R5764:Ly75
|
UTSW |
2 |
60,318,439 (GRCm38) |
missense |
probably benign |
|
|
R5896:Ly75
|
UTSW |
2 |
60,383,146 (GRCm38) |
missense |
probably benign |
|
|
R6025:Ly75
|
UTSW |
2 |
60,375,962 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6113:Ly75
|
UTSW |
2 |
60,368,873 (GRCm38) |
missense |
probably benign |
0.04 |
|
R6448:Ly75
|
UTSW |
2 |
60,299,045 (GRCm38) |
critical splice donor site |
probably null |
|
|
R6601:Ly75
|
UTSW |
2 |
60,318,376 (GRCm38) |
missense |
probably benign |
0.11 |
|
R6745:Ly75
|
UTSW |
2 |
60,308,179 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6955:Ly75
|
UTSW |
2 |
60,327,873 (GRCm38) |
missense |
possibly damaging |
0.49 |
|
R6960:Ly75
|
UTSW |
2 |
60,306,405 (GRCm38) |
missense |
probably benign |
|
|
R7100:Ly75
|
UTSW |
2 |
60,306,434 (GRCm38) |
missense |
probably benign |
|
|
R7110:Ly75
|
UTSW |
2 |
60,376,184 (GRCm38) |
missense |
probably benign |
0.31 |
|
R7203:Ly75
|
UTSW |
2 |
60,323,852 (GRCm38) |
nonsense |
probably null |
|
|
R7291:Ly75
|
UTSW |
2 |
60,329,993 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R7308:Ly75
|
UTSW |
2 |
60,334,515 (GRCm38) |
missense |
probably benign |
0.04 |
|
R7447:Ly75
|
UTSW |
2 |
60,334,474 (GRCm38) |
nonsense |
probably null |
|
|
R7512:Ly75
|
UTSW |
2 |
60,334,563 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7595:Ly75
|
UTSW |
2 |
60,293,827 (GRCm38) |
missense |
probably benign |
0.01 |
|
R7976:Ly75
|
UTSW |
2 |
60,365,088 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8005:Ly75
|
UTSW |
2 |
60,332,934 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8171:Ly75
|
UTSW |
2 |
60,314,228 (GRCm38) |
missense |
possibly damaging |
0.51 |
|
R8392:Ly75
|
UTSW |
2 |
60,349,940 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8705:Ly75
|
UTSW |
2 |
60,318,385 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R8714:Ly75
|
UTSW |
2 |
60,334,485 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8798:Ly75
|
UTSW |
2 |
60,323,926 (GRCm38) |
missense |
probably benign |
0.32 |
|
R8799:Ly75
|
UTSW |
2 |
60,348,441 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8834:Ly75
|
UTSW |
2 |
60,331,089 (GRCm38) |
missense |
probably benign |
|
|
R8990:Ly75
|
UTSW |
2 |
60,358,559 (GRCm38) |
missense |
probably benign |
0.10 |
|
R9015:Ly75
|
UTSW |
2 |
60,316,098 (GRCm38) |
missense |
probably benign |
|
|
R9547:Ly75
|
UTSW |
2 |
60,330,725 (GRCm38) |
critical splice donor site |
probably null |
|
|
R9628:Ly75
|
UTSW |
2 |
60,327,941 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9659:Ly75
|
UTSW |
2 |
60,338,321 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9660:Ly75
|
UTSW |
2 |
60,323,840 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9747:Ly75
|
UTSW |
2 |
60,306,328 (GRCm38) |
critical splice donor site |
probably null |
|
|
X0025:Ly75
|
UTSW |
2 |
60,354,475 (GRCm38) |
missense |
probably damaging |
1.00 |
|
Z1177:Ly75
|
UTSW |
2 |
60,352,133 (GRCm38) |
missense |
possibly damaging |
0.65 |
|
Z1177:Ly75
|
UTSW |
2 |
60,350,004 (GRCm38) |
nonsense |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- GATGATACCACTTAGGGAACGCCAC -3'
(R):5'- AGGTCATGAGCAGTCCCTTCCTAC -3'
Sequencing Primer
(F):5'- caagaaggcagaggcagg -3'
(R):5'- GCGAATCGAGTTTCGAATGG -3'
|
| Posted On |
2013-04-24 |
Incidental Mutation